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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4413 |
Poseltinib
|
||
Poseltinib 是一种具有口服活性,选择性,不可逆的小分子Bruton 酪氨酸激酶 (BTK) 抑制剂,IC50为 1.95 nM,对BTK 的选择性分别是 BMX,TEC 和 TXK 的 0.3,2.3 和 2.4 倍。Poseltinib 可共价结合 BTK 的活性位点 (半胱氨酸 481 残基),并显示出对 B 细胞受体 (BCR),Fc 受体 (FcR),Toll 样受体 (TLR) 介导的信号传导的有效抑制。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3563 |
Caesalmin B
|
Antifection | Microbiology/Virology |
Caesalmin B shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro. | |||
TN4666 |
Norcaesalpinin E
|
Antifection | Microbiology/Virology |
Norcaesalpinin E shows antimalarial activity against the malaria parasite Plasmodium falciparum FCR-3/A2 clone in vitro, with an IC50 value of 0.090 microM. | |||
TN2747 |
2-Acetoxy-3-deacetoxycaesaldekarin E
|
Antifection | Microbiology/Virology |
2-Acetoxy-3-deacetoxycaesaldekarin E shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00800 |
CD32B/Fcgr2b Protein, Mouse, Recombinant (His)
Fc fragment of IgG, low affinity IIb, receptor (CD32),Ly-17,... |
Mouse | HEK293 Cells |
CD32B/Fcgr2b Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.7 kDa and the accession number is A0A0B4J1E6. | |||
TMPY-02906 |
CD16b Protein, Human, Recombinant (NA2,His)
CD16,FCRIIIb,FCR-10,FCG3,CD16b,Fc fragment... |
Human | CHO Cells |
CD16b Protein, Human, Recombinant (NA2,His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 22.2 kDa and the accession number is O75015.2. | |||
TMPY-00701 |
CD16b Protein, Human, Recombinant (NA2, His)
Fc gamma RIIIb,FCR-10,FCRIIIb,Fc γ RIIIb... |
Human | HEK293 Cells |
CD16b Protein, Human, Recombinant (NA2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.2 kDa and the accession number is O75015.2. | |||
TMPY-01964 |
CD16a Protein, Human, Recombinant (F176V, His)
FCGRIII,Fc gamma RIIIa,FCR-10,FCRIII,... |
Human | HEK293 Cells |
The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells. CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the... | |||
TMPK-01041 |
FcRH6 /FCRL6 Protein, Human, Recombinant (hFc)
Fc receptor-like 6,FcRL6,IFGP6,FLJ16056,FcR |
Human | HEK293 Cells |
A surprising number of Fc receptor (FcR) relatives have been recognized recently with the potential capacity to modulate innate and adaptive immune responses. The six human FcR homologs (FcRH1-6), which belong to a phylogenetically conserved gene family, have variable numbers of extracellular immunoglobulin domains of five different subtypes. All but one of these new receptors, FcRH6, are expressed on B cells at different stages in differentiation. | |||
TMPK-00618 |
FcRH5/FcRL5 Protein, Human, Recombinant (His)
FcR-like protein 5,CD307,BXMAS1,FcRH5,IFGP... |
Human | HEK293 Cells |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971. | |||
TMPY-01986 |
CD32B/Fcgr2b Protein, Mouse, Recombinant (His & Avi), Biotinylated
Fcgr2a,Fc fragment of IgG, low affinity IIb, receptor (CD32)... |
Mouse | HEK293 Cells |
CD32B/Fcgr2b Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.9 kDa and the accession number is A0A0B4J1E6. | |||
TMPK-01042 |
FcRH6/FCRL6 Protein, Human, Recombinant (His)
Fc receptor homolog 6,IFGP6,FcR-like protein 6,FLJ1... |
Human | HEK293 Cells |
Fc receptor-like 6 (FCRL6), the most recently characterized member of the FCRL family, is a cell surface glycoprotein with tyrosine-based regulatory potential. An extensive survey of human hematopoietic tissues disclosed that FCRL6 expression by NK- and T-cell subpopulations increases as a function of differentiation and is remarkably restricted to mature lymphocytes with cytotoxic capability. | |||
TMPY-01961 |
CD16b Protein, Human, Recombinant (NA2)
Fc γ RIIIb,Fc gamma RIIIb,CD16b,FCGR3,Fc fragment of IgG r... |
Human | E. coli |
CD16b Protein, Human, Recombinant (NA2) is expressed in E. coli expression system. The predicted molecular weight is 20 kDa and the accession number is O75015.2. | |||
TMPY-04827 |
CD16b Protein, Human, Recombinant (SH, His)
CD16b,FCRIII,FCG3,FCR-10,FCGR3,FCR |
Human | HEK293 Cells |
CD16b Protein, Human, Recombinant (SH, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.3 kDa and the accession number is A0A3B3ISU3. | |||
TMPY-05125 |
CD16b Protein, Human, Recombinant (NA2,His & Avi), Biotinylated
Fc γ RIIIb,Fc gamma RIIIb,CD16,CD16b,FCRIII,F... |
Human | HEK293 Cells |
CD16b Protein, Human, Recombinant (NA2,His & Avi), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.1 kDa and the accession number is O75015.2. | |||
TMPY-05097 |
CD16b Protein, Human, Recombinant (NA1s, His)
Fc γ RIIIb,CD16,Fc fragment of IgG receptor IIIb,Fc gamma ... |
Human | HEK293 Cells |
CD16b Protein, Human, Recombinant (NA1s, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.4 kDa and the accession number is AAA35881.1. | |||
TMPY-06550 |
CD16b Protein, Human, Recombinant (NA1, His & Avi), Biotinylated
Fc fragment of IgG receptor IIIb,CD16,FCRIII,Fc gam... |
Human | HEK293 Cells |
CD16b Protein, Human, Recombinant (NA1, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.75 kDa and the accession number is AAA35881.1. | |||
TMPY-04328 |
CD16b Protein, Human, Recombinant (NA2), Biotinylated
CD16b,Fc fragment of IgG receptor IIIb,FCG3,FCRIII,... |
Human | E. coli |
CD16b Protein, Human, Recombinant (NA2), Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 20 kDa and the accession number is O75015.2. | |||
TMPY-05098 |
CD16b Protein, Human, Recombinant (NA2,His & Avi)
CD16,Fc gamma RIIIb,Fc fragment of IgG receptor IIIb,FCGR3,... |
Human | HEK293 Cells |
CD16b Protein, Human, Recombinant (NA2,His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24.1 kDa and the accession number is O75015.2. | |||
TMPK-01145 |
FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated
CD307,FcRL5,FcR-like protein 5,FCR |
Human | HEK293 Cells |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 94.19 kDa and the accession number is Q96RD9-1. | |||
TMPY-03064 |
Fc epsilon RI Protein, Mouse, Recombinant (hFc)
α polypeptide,FcERI,Fc ε RI,Fcr-5,alpha polypeptide... |
Mouse | HEK293 Cells |
Fc epsilon RI Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P20489. | |||
TMPK-00460 |
Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi), Biotinylated
CD16B,FcgRIIIB,FCG3B,FCGR3,Fc γ RIIIB/CD16b (NA2),CD16,F... |
Human | HEK293 Cells |
Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells wit... | |||
TMPK-00459 |
Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi)
FCGR3,FCGR3B,CD16B,Fc γ RIIIB/CD16b (NA2),CD16b (NA2),IGFR3,... |
Human | HEK293 Cells |
Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi ta... | |||
TMPK-01039 |
FcRH5/FcRL5 Protein, Mouse, Recombinant (His)
CD307e,FcRL5,BXMAS1MGC119592,IFGP5,FcRH5,B... |
Mouse | HEK293 Cells |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.7 kDa and the accession number is Q68SN8-1. | |||
TMPK-00619 |
FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
IFGP5,CD307,FCRH5MGC119593,FLJ00397,DKFZp667E2019,B... |
Human | HEK293 Cells |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971. | |||
TMPK-01115 |
Fc gamma RIII/CD16 Protein, Cynomolgus, Recombinant (His)
FcgRIII,FCR-10,FcRIII,IMD20,FCG3,CD16A,FCG... |
Cynomolgus | HEK293 Cells |
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set. | |||
TMPY-01965 |
CD16a Protein, Human, Recombinant (176 Phe, His & Avi)
IMD20,IGFR3,FCGR3,Fc fragment of IgG, low affinity IIIa, rec... |
Human | HEK293 Cells |
CD16a Protein, Human, Recombinant (176 Phe, His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.1 kDa and the accession number is P08637-1. | |||
TMPY-02816 |
CD16a Protein, Human, Recombinant (176 Phe, His)
IGFR3,CD16,FCR-10,FCRIIIA,CD16A,Fc γ RIII... |
Human | CHO Cells |
CD16a Protein, Human, Recombinant (176 Phe, His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P08637-1. | |||
TMPY-00763 |
CD16a Protein, Human, Recombinant (176F, His)
FCR-10,CD16A,IGFR3,Fc gamma RIIIa,Fc fragment of I... |
Human | HEK293 Cells |
CD16a Protein, Human, Recombinant (176F, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P08637-1. | |||
TMPJ-00610 |
hFcRL1 Protein, Mouse, Recombinant (His)
FcR-like protein 1,BXMAS1-like protein 1,mIFGP1,Fc ... |
Mouse | HEK293 Cells |
Mouse Fc receptor-like protein 1 (FCRL1) is a single-pass type I membrane protein. It is expressed in B-cells at the various stages of differentiation. Mouse FCRL1 consists of a 203 amino acid (aa) extracellular domain (ECD) with two Ig‑like domains, a 21 aa transmembrane segment, and a 103 aa cytoplasmic domain with two immunotyrosine activation motifs (ITAMs). FCRL1 is likely not a receptor for immunoglobulin. It may function as an activating coreceptor in B-cells and B-cells differentiation. | |||
TMPK-00791 |
Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi)
FCG3,IGFR3,FcgRIIIA,FCGR3,Fc γ RIIIA,FCGR3A,CD16,FcR |
Human | HEK293 Cells |
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is P08637-1. | |||
TMPY-01967 |
CD16a Protein, Human, Recombinant (176 Val, His & Avi)
IMD20,FCRIII,Fc gamma RIIIa,FCGRIII,FCR-1... |
Human | HEK293 Cells |
CD16a Protein, Human, Recombinant (176 Val, His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.6 kDa and the accession number is AAH17865.1. | |||
TMPY-01982 |
CD16a Protein, Human, Recombinant (176F, His & Avi), biotinylated
CD16A,FCG3,FCGRIII,FCR-10,FCRIIIA,Fc gamma... |
Human | HEK293 Cells |
CD16a Protein, Human, Recombinant (176F, His & Avi), biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.1 kDa and the accession number is P08637-1. | |||
TMPY-01981 |
CD16a Protein, Human, Recombinant (F176V, His & Avi), Biotinylated
IMD20,FCRIIIA,FCG3,Fc fragment of IgG, low affinity... |
Human | HEK293 Cells |
CD16a Protein, Human, Recombinant (F176V, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.6 kDa and the accession number is P08637-1. | |||
TMPK-00599 |
Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc)
FCGR3,IGFR3,FcR-10,Fc γ RIIIA/CD16a (V176) Domain 2... |
Human | HEK293 Cells |
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 35.29 kDa and the accession number is AAH17865. | |||
TMPK-00597 |
Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi)
CD16,FcRIII,IMD20,IGFR3,FCG3,Fc γ RIIIA,CD16A,FCGR3... |
Human | HEK293 Cells |
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is AAH17865. | |||
TMPK-00598 |
Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated
Fc gamma RIIIA,Fc γ RIIIA,FCGR3,FcRIII,FCG3,IGFR3,F... |
Human | HEK293 Cells |
The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. | |||
TMPK-00792 |
Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi), Biotinylated
FCGR3A,FcRIII,FCGR3,Fc γ RIIIA,CD16A,FcgRIIIA,IGFR3... |
Human | HEK293 Cells |
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (F176) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is P08637-1. | |||
TMPK-00240 |
Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi)
FcgRI,IGFR1,FCE1A,FCGR1A,Fc-γ RIA,Fc gamma RI,Fc-gamma RIA,F... |
Human | HEK293 Cells |
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 33.5 kDa and... | |||
TMPK-00241 |
Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi), Biotinylated
FcERI,CD64,FLJ18345,IGFR1,Fc gamma RI,Fcgr,Fcr,Fc γ... |
Human | HEK293 Cells |
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight i... | |||
TMPJ-00419 |
CD16b Protein, Human, Recombinant (hFc & His)
Fc-γ RIII-beta,FCG3,FcR-10,Fc-gamma RIII-β,FCGR3,FC... |
Human | HEK293 Cells |
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of infl... | |||
TMPY-03075 |
FcRH1/FCRL1 Protein, Mouse, Recombinant (His)
Fcrh1s,Bxmas1,A230020G22Rik,Ifgp1,Fcrh1l,B... |
Mouse | HEK293 Cells |
FcRH1/FCRL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.6 kDa and the accession number is Q8R4Y0-2. | |||
TMPY-04272 |
FcRH2/FCRL2 Protein, Human, Recombinant (His)
IFGP4,FCRH2,CD307b,SPAP1,SPAP1B,Fc receptor like 2,... |
Human | HEK293 Cells |
Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in CLL (B-cell chronic lymphocytic leukemia). | |||
TMPH-01330 |
FCRL3 Protein, Human, Recombinant (His)
|
Human | E. coli |
FCRL3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 67.4 kDa and the accession number is Q96P31. | |||
TMPY-01664 |
FcRH1/FCRL1 Protein, Human, Recombinant (His)
IFGP1,CD307a,FCRH1,IRTA5,Fc receptor like 1 |
Human | HEK293 Cells |
FcRH1/FCRL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.6 kDa and the accession number is Q96LA6-1. | |||
TMPJ-00605 |
GPVI Protein, Mouse, Recombinant (His)
Glycoprotein 6,GP6,glycoprotein VI (platelet),GPVI,GPIV,MGC1... |
Mouse | HEK293 Cells |
Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregation and thrombin generation. GPVI is also a secondary receptor required for platelet spreading on laminin. GPVI associates with the Fc receptor gamma -chain via charged aa in the TM domains of GPVI (arginine) and the FcR gamma (aspartic acid). Collagen binding by the GPVI Ig-like... | |||
TMPJ-00534 |
hFcgR4 Protein, Mouse, Recombinant (His)
Low Affinity Immunoglobulin γ Fc Region Receptor IV,FcgR4,Lo... |
Mouse | HEK293 Cells |
Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of sensory perception of pain, wound healing etc. Three groups are included for Fc γ receptors (FcR), and they are Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). Among these, CD64 possess high affinity even for monomeric IgG, while CD32 and CD16 display a relative lower affinity ... |