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Search Results for " cyclo(pro-pro) "

9

抑制剂 & 化合物

18

天然产物

1

同位素

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Cat. No.	Product Name	Target	Signaling Pathways
T7511	Cyclo(his-pro)	NF-κB; Endogenous Metabolite	Metabolism; NF-κB
	Cyclo(his-pro) 是一种口服具有活力的，结构上与促甲状腺激素释放激素相关的环状二肽。它能够抑制NF-κB 核积累，也能够穿越脑血屏障并影响多种炎症和应激反应。
TN6672	Cyclo(L-Phe-L-Pro)	Free radical scavengers; COX; Antibacterial; Antifungal	Immunology/Inflammation; Microbiology/Virology; Neuroscience; oxidation-reduction
	Cyclo(L-Phe-L-Pro) 具有广谱抗菌和抗真菌活性。 Cyclo(L-Phe-L-Pro) 对耐甲氧西林金黄色葡萄球菌和棉子肠球菌具有活性。
TP1186	Cyclo(Phe-Pro) 六氢-3-(苯基甲基)吡咯并[1,2-A]吡嗪-1,4-二酮,A-64863,Cyclo(phenylalanylprolyl)	Others	Others
	Cyclo(Phe-Pro) (A-64863) 是创伤弧菌的群体感应分子，能够与 RIG-I 的特异性相互作用，阻碍 RIG-I 的多泛素化，并抑制 IRF-3 的激活和 I 型干扰素的产生。它提高 HCV 和流感病毒的易感性。
TP2333	cyclo(L-Pro-L-Tyr)	Others	Others
	cyclo(L-Pro-L-Tyr) 是真菌和细菌的次生代谢产物。
T125115	Cyclo(L-Leu-L-Pro)	Antifungal	Microbiology/Virology
	Cyclo(L-Leu-L-Pro) 是一种来自芝麻假单胞菌BC42的化合物，具有抗真菌活性，抑制真菌病原体，抑制黄曲霉增殖。Cyclo(L-Leu-L-Pro) 抑制分生孢子的萌发和分生孢子的形成，可用于农业生物防治。
T124635	Cyclo(L-Pro-L-Ile)
	Cyclo(L-Pro-L-Ile) 是一种来自苏云金芽孢杆菌双酮哌嗪，可诱发中度超敏反应，可用于研究松树枯萎病。
T125120	Cyclo(L-Pro-L-Val)	IκB/IKK; NOS; NF-κB; COX; Antibacterial	Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
	Cyclo(L-Pro-L-Val) 是从辣椒溶杆菌AZ2和白斑分枝杆菌果实中提取出的 2,5-二酮哌嗪，具有抗炎活性，对植物病原微生物 (如 R. fascians LMG 3605) 具有毒性活性，能抑制革兰氏阳性植物病原菌。Cyclo(L-Pro-L-Val) 以浓度依赖性方式显著抑制了IKKα、IKKβ、IκBα和NF-κB 的磷酸化以及iNOS 和COX-2的活化，是治疗炎症相关疾病的潜在治疗剂。
TP1186L	Cyclo(Phe-Pro) acetate(14705-60-3 free base) Cyclo(phenylalanylprolyl) acetate,A-64863 acetate	Others	Others
	Cyclo(Phe-Pro) acetate(14705-60-3 free base) 是一些细菌和真菌的次级代谢产物，也是由创伤弧菌产生的。
T80142	Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) c(GRGDSP)	Integrin	Cytoskeletal Signaling
	Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)（c(GRGDSP)）为RGD 抑制肽。该化合物作为合成的α5β1整联蛋白配体，能够竞争性阻断 invasin（Inv）与Caco-2细胞表面α5β1整联蛋白的相互结合。

化合物

Cyclo(his-pro)

Cat.No: T7511

Target: NF-κB, Endogenous Metabolite

Cyclo(L-Phe-L-Pro)

Cat.No: TN6672

Target: Free radical scavengers, COX, Antibacterial, Antifungal

Cyclo(Phe-Pro)

Cat.No: TP1186

Synonym: 六氢-3-(苯基甲基)吡咯并[1,2-A]吡嗪-1,4-二酮,A-64863,Cyclo(phenylalanylprolyl)

Target: Others

cyclo(L-Pro-L-Tyr)

Cat.No: TP2333

Target: Others

Cyclo(L-Leu-L-Pro)

Cat.No: T125115

Target: Antifungal

Cyclo(L-Pro-L-Ile)

Cat.No: T124635

Cyclo(L-Pro-L-Val)

Cat.No: T125120

Target: IκB/IKK, NOS, NF-κB, COX, Antibacterial

Cyclo(Phe-Pro) acetate(14705-60-3 free base)

Cat.No: TP1186L

Synonym: Cyclo(phenylalanylprolyl) acetate,A-64863 acetate

Target: Others

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)

Cat.No: T80142

Synonym: c(GRGDSP)

Target: Integrin

Cat. No.	Product Name	Target	Signaling Pathways
TN6686	Cyclo(Pro-Pro)
	Cyclo(Pro-Pro) tasted bitter.Verpacamides A-D, a sequence of C11N5 diketopiperazines relating cyclo(Pro-Pro) to cyclo(Pro-Arg), from the marine sponge Axinella vaceleti is possible biogenetic precursors of pyrrole-2-aminoimidazole alkaloids.
TN6431	Cyclo(Pro-Ala)	Others	Others
	Cyclo(Pro-Ala) 是一种天然产品。
TMA2613	Cyclo(Pro-Leu) Cyclo-L-leu-L-pro,Cyclo-L-prolyl-L-leucine,Cyclo(leucyloprolyl)	Others	Others
	Cyclo(Pro-Leu) (Cyclo-L-prolyl-L-leucine) 是一种源自海洋的天然产物，具有盐水虾的杀伤力。
TN6675	Cyclo(Pro-Val) Cyclo(prolylvalyl)	Antibacterial; Antifungal	Microbiology/Virology
	Cyclo(Pro-Val) (Cyclo(prolylvalyl)) 是从海洋真菌中获得的，具有中等的抗真菌活性和较弱的抗肿瘤活性。 Cyclo(Pro-Val) 抑制枯草芽孢杆菌的生长，MIC 为 0.8 g/L。
TN6673	Cyclo(L-Phe-trans-4-hydroxy-L-Pro) L-Phe-trans-4-hydroxy-L-Pro,环(L-苯丙氨酰-反式-4-羟基-L-脯氨酸),Cyclo(L-phenylalanyl-trans-4-hydroxy-L-proline)	Others	Others
	Cyclo(L-Phe-trans-4-hydroxy-L-Pro) (Cyclo(L-phenylalanyl-trans-4-hydroxy-L-proline))是一种存在于Phellinus igniarius 中的天然产物。
T3208	Brevianamide F Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp)	BCRP; PI3K; Antibacterial	Membrane transporter/Ion channel; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Brevianamide F (Cyclo(L-Pro-L-Trp)) 是一种从Colletotrichum gloeosporioides 中分离得到的真菌毒素，属于天然存在的 2,5-二酮哌嗪类，具有抗菌活性。它具有PI3Kα抑制活性，IC50值为 4.8 µM。
TN6674	Cyclo-(Pro-Gly) Cyclo(Pro-Gly)
	Cyclo(Pro-Gly) is an active metabolite of piracetam-N-phenylacetyl-L-prolylglycine (GWS-111), it shows a greater resistance to an enzymatic effect than natural neuropeptides. Cyclo-(Gly-Pro) shows cytotoxicity at the concentration of 10 umol/L, it inhibit
TN6683	Cyclo(Pro-Trp)
	Cyclo(Pro-Trp) and cyclo(Phe-Pro) show broad spectrum antibacterial properties.
TN6678	Cyclo(Tyr-Pro)
	Cyclo(Tyr-Pro) shows antibacterial activity towards several marine bacterial species, it also shows weak antagonistic activity against VEGFR2 -CD. Cyclo(Tyr-Pro) and cyclo(Pro-Val) are toxic to both suspension cells and seedlings of Pinus thunbergii, whic
TN6445	Cyclo(Gly-L-Pro)
	Cyclo(Gly-(L)-Pro) shows immunostimulatory properties. Cyclo(Gly-l-Pro) exhibits potent inhibition of TNF-α release with the IC50 values of 4.5 ug/mL, respectively, it also exhibits significant diminution of IL-1β and IL-6 mRNA-expression levels and NO pr
TN6670	Cyclo(D-Val-L-Pro)
	Cyclo(D-Val-L-Pro) 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6670，CAS号为 27483-18-7。
TN6040	Cyclo(D-Phe-L-Pro)
	Cyclo(D-Phe-L-Pro) is a natural product from Phellinus igniarius.
TN6043	Cyclo(D-Leu-L-Pro)
	Cyclo(D-Leu-L-Pro) shows antitumour and antifungal activities.
T41332	Cyclo(D-Ala-L-Pro)
	Cyclo(D-Ala-L-Pro) 在生命科学相关研究中具有广泛的应用。
TN6041	Cyclo(L-Ala-L-Pro) Cyclo(alanylprolyl)
	Cyclo(L-Ala-L-Pro) and cyclo(L-Val-L-Pro) inhibit aflatoxin production of Aspergillus parasiticus and Aspergillus flavus in liquid medium at concentrations of several hundred uM without affecting fungal growth.
TN6671	Cyclo(L-Leu-trans-4-hydroxy-L-Pro)
	Cyclo(L-Leu-trans-4-hydroxy-L-Pro) is a natural product from Phellinus igniarius.
TN7380	Cyclo(Ser-Pro)	Others	Others

T61171	Cyclo(his-pro) TFA	Others	Others
	Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the blood-brain barrier and impact various inflammatory and stress responses [1, 2].

天然产物

Cyclo(Pro-Pro)

Cat.No: TN6686

Cyclo(Pro-Ala)

Cat.No: TN6431

Target: Others

Cyclo(Pro-Leu)

Cat.No: TMA2613

Synonym: Cyclo-L-leu-L-pro,Cyclo-L-prolyl-L-leucine,Cyclo(leucyloprolyl)

Target: Others

Cyclo(Pro-Val)

Cat.No: TN6675

Synonym: Cyclo(prolylvalyl)

Target: Antibacterial, Antifungal

Cyclo(L-Phe-trans-4-hydroxy-L-Pro)

Cat.No: TN6673

Synonym: L-Phe-trans-4-hydroxy-L-Pro,环(L-苯丙氨酰-反式-4-羟基-L-脯氨酸),Cyclo(L-phenylalanyl-trans-4-hydroxy-L-proline)

Target: Others

Cat.No: T3208

Synonym: Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp)

Target: BCRP, PI3K, Antibacterial

Cyclo-(Pro-Gly)

Cat.No: TN6674

Synonym: Cyclo(Pro-Gly)

Cyclo(Pro-Trp)

Cat.No: TN6683

Cyclo(Tyr-Pro)

Cat.No: TN6678

Cyclo(Gly-L-Pro)

Cat.No: TN6445

Cyclo(D-Val-L-Pro)

Cat.No: TN6670

Cyclo(D-Phe-L-Pro)

Cat.No: TN6040

Cyclo(D-Leu-L-Pro)

Cat.No: TN6043

Cyclo(D-Ala-L-Pro)

Cat.No: T41332

Cyclo(L-Ala-L-Pro)

Cat.No: TN6041

Synonym: Cyclo(alanylprolyl)

Cyclo(L-Leu-trans-4-hydroxy-L-Pro)

Cat.No: TN6671

Cyclo(Ser-Pro)

Cat.No: TN7380

Target: Others

Cyclo(his-pro) TFA

Cat.No: T61171

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0171	Cyclo-(L-Pro-L-Ile)-d4 (rac)
	Cyclo-(L-Pro-L-Ile)-d4 (rac) 是 Cyclo-(L-Pro-L-Ile) (rac) 的氘代化合物。Cyclo-(L-Pro-L-Ile) (rac) 的 CAS 号为 57089-60-8。

同位素

Cyclo-(L-Pro-L-Ile)-d4 (rac)

Cat.No: TMIH-0171

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