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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T82700 |
Cn2 toxin
β-Mammal toxin Cn2 |
||
Cn2 toxin为一β类毒素,具有与电压门控钠通道(Nav)的电压感应域结合的能力。 | |||
T11373 |
GCN2-IN-1
A-92 |
Others | Others |
GCN2-IN-1 (A-92) 是一种有效的一般性调控阻遏蛋白激酶 2 抑制剂,可作为化疗药物用于癌症治疗的研究。 | |||
T11374 |
GCN2-IN-6
|
Others; PERK | Apoptosis; Others |
GCN2-IN-6 经酶法和细胞分析证实,是一种口服有效GCN2抑制剂,IC50分别为1.8 nM 和9.3 nM。GCN2-IN-6 还是 eIF2α 激酶PERK 抑制剂,在酶法测定和细胞测定中的IC50分别为 0.26 nM 和 230 nM。 | |||
T7494 |
TCN238
TCN 238 |
GluR | Neuroscience |
TCN238 是一种可口服的代谢型谷氨酸受体 4 正变构调节剂,EC50值为 1 μM。 | |||
T11375 |
GCN2iB
|
Others; Autophagy | Autophagy; Others |
GCN2iB 是一种 ATP 竞争性的一般控制非抑制性 2 抑制剂,IC50 为 2.4 nM。 | |||
T69829 |
GCN2iB acetate
|
||
GCN2iB is a GCN2 inhibitor. GCN2iB may be useful for the treatment of cancer. The inhibition of GCN2 sensitizes cancer cells with low basal-level expression of asparagine synthetase (ASNS) to the antileukemic agent L-asparaginase (ASNase) in vitro and in vivo. | |||
T63699 |
GCN2-IN-7
|
||
GCN2-IN-7 是选择性的、口服具有活力的 general control nonderepressible 2(GCN2) 抑制剂,其 IC50 值为 5 nM,在体内表现出抗肿瘤效果。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00361 |
Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His)
Toxin 2,Beta-mammal toxin Cn2,Tox... |
Centruroides noxius | P. pastoris (Yeast) |
Mammal beta-toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the activation voltage to more negative potentials. This toxin is active against mammals. Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 9.6 kDa and the accession number is P01495. | |||
TMPY-01773 |
CNDP2 Protein, Human, Recombinant (His)
CNDP dipeptidase 2 (metallopeptidase M... |
Human | Baculovirus Insect Cells |
CNDP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.2 kDa and the accession number is CAC69883.1. | |||
TMPH-01199 |
CNDP2 Protein, Human, Recombinant (E. coli, His)
HEL-S-13,CPGL,Threonyl dipeptidase,PEPA,CNDP dipept... |
Human | E. coli |
CNDP2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPY-01739 |
CNDP2 Protein, Mouse, Recombinant (His)
C76600,Dip-2,Pep-1,Cn2,0610010E05... |
Mouse | Baculovirus Insect Cells |
CNDP2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.22 kDa and the accession number is Q9D1A2. | |||
TMPY-01003 |
TCN2 Protein, Human, Recombinant (His)
II,TC-2,D22S750,TC,TCII,TC2 |
Human | HEK293 Cells |
TCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P20062-1. | |||
TMPY-00873 |
Lipocalin-2/LCN2 Protein, Human, Recombinant (His)
MSFI,24p3,lipocalin 2,NGAL,Lipocalin-2... |
Human | HEK293 Cells |
Lipocalin-2/LCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P80188-1. | |||
TMPY-00988 |
Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)
24p3,lipocalin 2,AW212 |
Mouse | HEK293 Cells |
Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.3 kDa and the accession number is P11672. | |||
TMPY-02316 |
Lipocalin-2/LCN2 Protein, Rat, Recombinant (His)
lipocalin 2 |
Rat | Baculovirus Insect Cells |
Lipocalin-2/LCN2 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 21.9 kDa and the accession number is P30152. | |||
TMPJ-01163 |
CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)
CTGF,Connective tissue growth factor |
Human | HEK293 Cells |
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physio... | |||
TMPY-05203 |
Lipocalin-2/LCN2 Protein, Mouse, Recombinant
lipocalin 2,AW21222<... |
Mouse | HEK293 Cells |
Lipocalin-2/LCN2 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.9 kDa and the accession number is P11672. | |||
TMPJ-01113 |
RCN2 Protein, Human, Recombinant (His)
Reticulocalbin-2,ERC55,RCN2,E6BP |
Human | HEK293 Cells |
Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 cou... | |||
TMPK-01000 |
CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated
CTGF,CCN2,IBP-8,IGFBP8,Fisp12,CTG... |
Human | HEK293 Cells |
Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells. CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells wi... | |||
TMPJ-01162 |
CTGF/CCN2 Protein, Human, Recombinant (hFc)
IGFBP8,Connective tissue growth factor,Hypertrophic chondroc... |
Human | HEK293 Cells |
CTGF/CCN2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 67-81 KDa and the accession number is Q5M8T4. | |||
TMPK-00672 |
CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His)
CTGRP,CTGF,IBP-8,CCN2,NOV2,HCS |
Rhesus | HEK293 Cells |
Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells. CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His ta... | |||
TMPH-01069 |
CTGF/CCN2 Protein, Human, Recombinant (His)
Hypertrophic chondrocyte-specific protein 24,CC... |
Human | E. coli |
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. CTGF/CCN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.1 kDa and... | |||
TMPJ-01161 |
CTGF/CCN2 Protein, Human, Recombinant
IGFBP-8,CCN family member 2,IBP-8,Connecti... |
Human | HEK293 Cells |
CTGF/CCN2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-25 KDa and the accession number is Q5M8T4. | |||
TMPY-03697 |
SCN2B Protein, Human, Recombinant (His)
ATFB14,sodium channel, voltage gated, type II beta subunit,s... |
Human | HEK293 Cells |
SCN2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.7 kDa and the accession number is O60939. | |||
TMPH-02568 |
CTGF/CCN2 Protein, Mouse, Recombinant (GST)
betaIG-M2,Connective tissue growth factor,Protein F... |
Mouse | E. coli |
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. | |||
TMPY-02192 |
TCN2 Protein, Mouse, Recombinant (His)
Tcn-2,transcobalamin II,AW208754 |
Mouse | HEK293 Cells |
TCN2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is O88968. | |||
TMPY-03183 |
SCN2B Protein, Human, Recombinant (hFc)
sodium channel, voltage gated, type II beta subunit,sodium c... |
Human | HEK293 Cells |
SCN2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is O60939. |