34
23
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T61147 |
Chitin synthase inhibitor 4
|
Antibiotic | Microbiology/Virology |
Chitin synthase inhibitor 4 是一种具有抗菌活性的几丁质合成酶(CHS)抑制剂。Chitin synthase inhibitor 4 是一种基于CHS 的化合物,是一种候选的杀菌剂。 | |||
T20019 |
Malachite green
Solid Green O,Solid Green Crystals O |
Others | Others |
Malachite green (Solid Green Crystals O) 是一种 N-甲基化二氨基三苯基甲烷染料,可用于着色。 | |||
T32668 |
Leucomalachite green
NSC36379,NSC 36379,隐色孔雀绿,NSC-36379 |
Others | Others |
Leucomalachite green (NSC-36379) 是孔雀石绿的主要代谢物,是潜在的致癌物、致畸物和诱变剂。它是一种三苯甲烷燃料,可用于检测血液。 | |||
T10789 |
Chitosan oligosaccharide
COS,壳聚糖低聚乳酸酯 |
AMPK | Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
Chitosan oligosaccharide (COS) 是 β-(1→4)-连接的 D-氨基葡萄糖的寡聚体,Chitosan oligosaccharide可激活 AMPK ,抑制NF-κB 和 MAPK在内的炎症信号通路。 | |||
TD0099 |
Malachite green oxalate
|
Apoptosis; Others; IκB/IKK; NF-κB | Apoptosis; NF-κB; Others |
Malachite green oxalate 是一种三苯基甲烷染料,可用于检测酶促反应中磷酸盐的释放。它也是一种选择性IKBKE 抑制剂,在体内外均表现出抗肿瘤活性。 | |||
T62475 | Chitin synthase inhibitor 7 | ||
Chitin synthase inhibitor 7 (compound 9c) 是一种 chitin synthase (CHS) 的有效抑制剂 (IC50: 0.37 nM)。Chitin synthase inhibitor 7 对耐药真菌具有广谱抗真菌作用。Chitin synthase inhibitor 7 能够用于研究真菌感染。 | |||
T79481 | Chitin synthase inhibitor 13 | ||
Chitin synthase inhibitor 13 (compound 12g) 为非竞争性几丁质合酶抑制剂,其IC50为106.7 μM,展现出广谱抗真菌活性。 | |||
T40466 |
Penta-N-acetylchitopentaose
|
||
Penta-N-acetylchitopentaose, a chemical compound, elicits the activation of plant defense systems. This compound also functions as a substrate for the Rhizobium leguminosarum nodulation protein NodL. | |||
T61398 |
Chitin synthase inhibitor 3
|
||
Chitin synthase inhibitor 3 (compound 2d) 是一种高效的chitin synthase抑制剂,具有0.16 mM的IC50值,并对candida albicans显示出1 μg/mL的MIC,表现出抗真菌活性。 | |||
T37567 |
4-Methylumbelliferyl β-D-N,N'-diacetylchitobioside
|
||
4-Methylumbelliferyl β-D-N,N'-diacetylchitobioside (4-μU-(GlcNAc)2) is a fluorogenic substrate for chitinases and chitobiosidases. 4-μU-(GlcNAc)2 is cleaved by chitinases and chitobiosidases to release the fluorescent moiety 4-μU. 4-μU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. | |||
T62246 | Chitin synthase inhibitor 8 | ||
Chitin synthase inhibitor 8 是一种 chitin synthase (CHS) 抑制剂,具有广谱抗真菌作用,能够用于真菌感染相关研究。 | |||
T62738 | Chitin synthase inhibitor 6 | ||
Chitin synthase inhibitor 6 (compound 9b) 是一种 chitin synthase (CHS) 的有效抑制剂 (IC50: 0.21 mM)。Chitin synthase inhibitor 6 对耐药真菌表现出广谱抗真菌效果,能够用于研究真菌感染。 | |||
T63353 | Chitin synthase inhibitor 11 | ||
Chitin synthase inhibitor 11 是一种高效的几丁质合酶 (CHS) 抑制剂,能够明显抑制 CHS 的活性 (IC50: 0.10 mM),具有广谱体外抑菌作用。Chitin synthase inhibitor 11 能够用于研究侵袭性真菌感染 (IFIs)。 | |||
T10788 | Chitinase-IN-2 | Others | Others |
Chitinase-IN-2 is an insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide. | |||
T62739 | Chitin synthase inhibitor 9 | ||
Chitin synthase inhibitor 9 是一种几丁质合成酶 (chitin synthase, CHS) 抑制剂,表现出广谱抗真菌效果。Chitin synthase inhibitor 9 能够用于进行真菌感染相关研究。 | |||
T78886 | Chitin synthase inhibitor 14 | ||
Chitin synthase inhibitor 14 (compound 4n),一种CHS抑制剂,展现出优异的抗真菌活性和对耐药真菌变异的有效抗性。 | |||
T74956 | Chitin synthase inhibitor 10 | ||
Chitin synthase inhibitor 10为一种高效的几丁质合酶(CHS)抑制剂,具有0.11 mM的IC50,表现出显著的CHS抑制活性。作为抗真菌剂,该化合物对包括C. albicans和C. neoformans在内的耐药真菌变体有效,适合用于侵袭性真菌感染(IFI)研究。 | |||
T37570 |
4-Methylumbelliferyl-β-D-N,N',N''-Triacetylchitotrioside
|
||
4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is a fluorogenic substrate for chitinases and chitotriosidases. 4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is cleaved by chitinases and chitotriosidases to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. ... | |||
T40327 |
Tetra-N-acetylchitotetraose
|
||
Tetra-N-acetylchitotetraose, a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia, stimulates plant defense systems. Moreover, it serves as a substrate for the CO deacetylase nodulation protein NodB in Rhizobium leguminosarum. | |||
T125643 |
7-Methylsudachitin
|
||
7-Methylsudachitin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125643,CAS号为 16520-78-8。 | |||
T37252 |
Chitoheptaose heptahydrochloride
|
||
Chitoheptaose heptahydrochloride is a chitosan oligosaccharide with antioxidant, anti-inflammatory, antiapoptotic, and cardioprotective properties. It effectively promotes the growth and photosynthesis parameters of wheat seedlings[1][2]. | |||
T62122 | Chitinase-IN-5 | ||
Chitinase-IN-5 (8i) 是一种几丁质酶OfChi-h 的有效抑制剂 (IC50: 0.051 μM),具有良好的杀虫作用。Chitinase-IN-5 能够用于研究绿色害虫防治和管理。 | |||
T73612 | Chitinase | ||
Chitinase 具有部分具有溶菌酶活性,广泛存在于细菌、真菌、动物和一些植物中。Chitinase 属于糖基水解酶家族大豆几丁质酶催化壳寡糖水解。 | |||
T62068 | Chitin synthase inhibitor 1 | ||
Chitin synthase inhibitor 1 是有效的、选择性的几丁质合酶 (CHS) 抑制剂,IC50值为0.12 mM。Chitin synthase inhibitor 1 强效抑制耐药真菌变体。 | |||
T40486 |
Hexa-N-acetylchitohexaose
N-Acetylchitohexaose |
Others | Others |
Hexa-N-acetylchitohexaose 可加强农作物的抗病性,可促使大豆木质化相关酶和抗氧化酶活性增加。Hexa-N-acetylchitohexaose 是溶菌酶的底物。Hexa-N-acetylchitohexaose 具有抗肿瘤活性,可抑制实体肿瘤生长。 | |||
T37850 |
Chitobiose Octaacetate
|
||
Chitobiose is a dimer of β-1,4 linked glucosamine units derived from chitin, which, in turn, is a long chain polymer of N-acetylglucosamine that is a primary component of fungal cell walls and arthropod exoskeletons. Chitobiose octaacetate is a form of chitobiose containing eight acetate groups. It is formed by the acetolysis of chitin. Chitobiose octaacetate can be used for the synthesis of chitobiose oxazoline and other chitin precursors. | |||
T75348 |
Malachite Green Carbinol base
|
||
Malachite Green Carbinol base (MGOH, MGCB) 是孔雀石绿(MG)的衍生物,无荧光。Malachite Green Carbinol base (MGOH, MGCB) 可作为 pH 调节剂,MGCB 分子在紫外光照射下释放 OH-,使 pH 值逐渐变化。MGCB 溶液在高压 UV 灯(500w, 50w /cm)照射下迅速由无色变为深绿色。 | |||
T63392 |
Chitin synthase inhibitor 5
|
||
Chitin synthase inhibitor 5 是一种几丁质合成酶的抑制剂 (IC50: 0.14 mM)。Chitin synthase inhibitor 5 表现出广谱的真菌抗活性,能够较好的抑制白色念珠菌、黄曲霉、烟毒念珠菌和新生念珠菌,能够用于研究真菌。 | |||
T10788L |
Chitinase-IN-2 hydrochloride
Chitinase-IN-2 hydrochloride (1579991-63-1 free base) |
Others | Others |
Chitinase-IN-2 hydrochloride 是昆虫几丁质酶抑制剂和N-乙酰氨基己糖苷酶抑制剂。 | |||
T61188 |
Chitin synthase inhibitor 2
|
||
Chitin synthase inhibitor 2 (compound 2b) is a highly potent inhibitor of chitin synthase, with an IC50 value of 0.09 mM and a K i value of 0.12 mM. This compound exhibits antimicrobial activities in vitro and demonstrates synergistic or additive effects when combined with fluconazole or polyoxin B [1]. | |||
T10787 |
Chitinase-IN-1
|
Others | Others |
Chitinase-IN-1 is an insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide. | |||
T63077 |
Chitin synthase inhibitor 12
|
||
Chitin synthase inhibitor 12 是一种几丁质合酶 (CHS) 抑制剂,具有优异的 CHS 抑制作用 (IC50: 0.16 mM)。Chitin synthase inhibitor 12 也是一种广谱抗真菌剂,对耐药真菌变体(如 C. albicans、C. neoformans)具有抗性。Chitin synthase inhibitor 12 能够用于研究侵袭性真菌感染 (IFIs)。 | |||
T62069 |
Chitinase-IN-4
|
||
Chitinase-IN-4 (compound 8f) 是一种有效的、选择性的 OfChi-h 抑制剂,其 IC50 值为 0.1 μM,具有良好的杀虫作用。 | |||
T23882 |
Chitinovorin B
|
||
Chitinovorin B is a beta-lactam antibiotic. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13708 |
Glycol chitosan
羟乙基脱乙酰壳多糖,乙二醇壳聚糖 |
Antibacterial | Microbiology/Virology |
Glycol chitosan 是具有亲水性乙二醇支链的壳聚糖衍生物。它抑制大肠杆菌,金黄色葡萄球菌和肠炎链球菌的生长,MIC 值分别为 4 μg/mL,32 μg/m L 和 <0.5 μg/mL。它可增强 Glycine max Harosoy 63W 细胞的膜通透性和渗漏。 | |||
T22291 |
Chitin
Chitin (From shrimp and crab shells) |
Others | Others |
Chitin 是一种大型的结构多糖,存在于真菌的细胞壁、昆虫的外骨骼以及鱼类和无脊椎动物的某些坚硬结构中。 | |||
T5729 |
L-quebrachitol
L-白雀木醇,(-)-白雀木醇 |
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
L-Quebrachitol 是一种从多种植物中分离得到的天然产物,能够触发 BMP-2 反应以及 Runx2、MAPK 和 Wnt/β-catenin 信号通路,诱导成骨细胞生成。 | |||
T1715 |
Chitosan (MW 150000)
壳聚糖,Chitosan,Poly(D-glucosamine),Deacetylated chitin |
Antibacterial; Antifungal | Microbiology/Virology |
Chitosan (MW 150000) (Deacetylated chitin) 是衍生自几丁质的聚阳离子线性多糖。它无毒,具有低致敏性,生物相容性和可生物降解性。它还具有抗肿瘤,抗细菌,抗真菌和抗氧化活性。 | |||
TN4610 |
N-Demethylechitamine
|
Others | Others |
N-Demethylechitamine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4610,CAS号为 60048-88-6。 | |||
T40487 |
N,N',N''-Triacetylchitotriose
|
||
N,N',N''-Triacetylchitotriose is a competitive inhibitor of lysozyme. | |||
TN2753 |
2-Deacetyltaxachitriene A
|
Others | Others |
2-Deacetyltaxachitriene A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2753,CAS号为 214769-96-7。 | |||
T38541 |
Chitobiose dihydrochloride
|
||
Chitobiose dihydrochloride is a chitosan oligosaccharide consisting of β-1,4-linked glucosamine units. | |||
T75645 | Echitamine chloride | ||
Echitamine chloride 是存在于 Alstonia scholaris 中的主要单萜吲哚生物碱,具有有效的抗肿瘤活性。Echitamine chloride 会诱导 DNA 片段化和细胞凋亡 (apoptosis)。Echitamine chloride 抑制胰腺脂肪酶 (pancreatic lipase),IC50为 10.92 µM。 | |||
T40436 |
N,N'-Diacetylchitobiose
|
||
N,N'-Diacetylchitobiose, a dimer of β(1,4) linked N-acetyl-D glucosamine, is derived from the hydrolysis of chitin. This compound serves as an alternative carbon source for E. coli. | |||
TN5102 |
Taxachitriene A
|
Others | Others |
Taxachitriene A is a natural product from the Chinese yew Taxus chinensis. | |||
T37253 |
Chitohexaose hexahydrochloride
|
||
Chitohexaose hexahydrochloride is a chitosan oligosaccharide compound that possesses anti-inflammatory properties. It exerts its anti-inflammatory effect by binding to the active sites of TLR4, thereby inhibiting inflammation induced by LPS. This compound has been supported by references [1] and [2]. | |||
T82509 |
Echitaminic acid
|
||
Echitaminic acid (compound 3) 是从印度尼西亚帝汶Alstonia sellers树干树皮中分离得到的生物碱。 | |||
T38561 |
Chitopentaose pentahydrochloride
|
||
Chitopentaose pentahydrochloride is an anti-inflammatory chitosan oligosaccharide that functions as a substrate for the gene encoding chitinase B (FjchiB). | |||
T38555 |
Chitotetraose tetrahydrochloride
|
||
Chitotetraose tetrahydrochloride is a short-chain chitin oligomer derived from arbuscular mycorrhizal (AM) fungi. This compound effectively activates the conserved symbiosis signaling pathway (CSSP) in actinorhizal plant species. | |||
TN2609 |
13-Deacetyltaxachitriene A
|
Others | Others |
13-Deacetyltaxachitriene A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2609,CAS号为 239800-99-8。 | |||
TN5103 |
Taxachitriene B
|
Others | Others |
Taxachitriene B is a natural product from the Chinese yew Taxus chinensis. | |||
TN3919 |
Echitoveniline
|
Others | Others |
Echitoveniline is a natural product from Alstonia venenata R.Br. | |||
T38557 |
Chitotriose trihydrochloride
|
||
Chitotriose trihydrochloride is an orally active chitooligosaccharide known for its antioxidant properties. It effectively inhibits the hydroxylation of benzoate to salicylate by H 2 O 2 in the presence of Cu 2+, with an IC 50 value of 80 μM. | |||
TN3917 |
Echitamine
|
Others | Others |
Echitamine chloride possesses anti-tumour activity in-vitro and in-vivo. | |||
TN3918 |
Echitovenidine
|
MAO | Metabolism; Neuroscience |
Echitovenidine shows monoamine oxidase inhibitor activity. | |||
T82737 |
Chitobiose
|
||
Chitobiose为壳寡糖,为β-1,4-氨基葡萄糖二聚体,具备口服活性及较高的抗氧化活性。 | |||
TN3103 |
5-Acetyltaxachitriene A
|
Others | Others |
5-Acetyltaxachitriene A is a natural product from Taxus mairei. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01290 |
CHIT1 Protein, Human, Recombinant (His)
chitinase 1 (chitotriosidase),CHIT |
Human | HEK293 Cells |
Chitotriosidase, also known as Chitinase-1 and CHIT1, is a member of the glycosyl hydrolase 18 family and Chitinase class II subfamily. It is a member of the mammalian chitinase family, structurally homologous to chitinases from other species, is synthesized and secreted by specifically activated macrophages. Chitotriosidase is a polymer of N-acetylglucosamine. Serum and plasma chitotriosidase activity is usually measured as the first step in diagnosis of Gaucher disease. Monitoring chitotriosid... | |||
TMPK-01127 |
AMCase/CHIA Protein, Mouse, Recombinant (His)
CHIT2,Chia1,AMCase,YNL,Acidic mammalian chit |
Mouse | HEK293 Cells |
Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. The expression of AMCase and CHIT-1 were differently modulated in HMMs at different stage of maturation. | |||
TMPK-01154 |
AMCase/CHIA Protein, Human, Recombinant (His)
YNL,AMCase,Chia1,CHIA,Acidic mammalian chitinase,EC... |
Human | HEK293 Cells |
Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. Despite that AMCase expression in the inflammation is under investigation, little is known regarding its regulation during macrophages'... | |||
TMPH-00051 |
Chitin deacetylase Protein, Amylomyces rouxii, Recombinant (His)
Chitin deacetylase,MrCDA,CDA |
Amylomyces rouxii | E. coli |
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitin deacetylase Protein, Amylomyces rouxii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is P50325. | |||
TMPH-03738 |
Endochitinase B Protein, Zea mays, Recombinant (His & Myc)
ChitB,CHIB,Endochitinase B,Seed chit |
Zea mays | E. coli |
Defense against chitin-containing fungal pathogens. | |||
TMPH-00187 |
Chitosanase Protein, Bacillus velezensis UCMB5033, Recombinant (His)
|
Bacillus velezensis UCMB5033 | E. coli |
N/A. Chitosanase Protein, Bacillus velezensis UCMB5033, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.4 kDa and the accession number is S6FZ94. | |||
TMPH-00135 |
Endochitinase Protein, Avena sativa, Recombinant (His)
|
Avena sativa | E. coli |
This protein functions as a defense against chitin-containing fungal pathogens. Endochitinase Protein, Avena sativa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.7 kDa and the accession number is P86181. | |||
TMPH-03708 |
Chitin-binding lectin Protein, Viscum album, Recombinant (His)
Chitin-binding lectin |
Viscum album | E. coli |
Chitin-binding lectin which is specific for N-acetylglucosamine oligomers. Chitin-binding lectin Protein, Viscum album, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 11.4 kDa and the accession number is P81859. | |||
TMPY-00603 |
YM1/Chitinase 3 Like 3 Protein, Mouse, Recombinant (His)
Ym1 |
Mouse | HEK293 Cells |
YM1/Chitinase 3 Like 3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.8 kDa and the accession number is O35744. |