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Targets Recommended: Mdm2 p53

18

抑制剂 & 化合物

7

天然产物

12

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T3184 Kevetrin hydrochloride

Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride

Mdm2; p53 Apoptosis
Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) 是一种小分子,是肿瘤抑制蛋白 p53 的激活剂,具有潜在的抗肿瘤活性。
T8987 Epiblastin A

Casein Kinase Metabolism; Stem Cells
Epiblastin A 是 ATP 竞争性的酪蛋白激酶 1 (CK1) 抑制剂,能够抑制 CK1α (IC50:8.9 µM)、 CK1δ (IC50:0.5 µM)、CK1 ɛ (IC50:4.7 µM)。它能够抑制 CK1 诱导外胚层干细胞重编程为胚胎干细胞。
T6721 Vinblastine

Microtubule Associated; AChR Cytoskeletal Signaling; Neuroscience
Vinblastine 抑制微管形成并抑制 nAChR 活性,IC50 为 8.9 μM,用于治疗某些类型的癌症。
T125427 Reblastatin

Reblastatin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125427,CAS号为 199333-57-8。
T29434 4-Desacetylvinblastine hydrazide

DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide

Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.
T37595 Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. aFGF (1-11) corresponds to amino acid residues 1-11 of the full length peptide.
T35769 Blasticidin A

Blasticidin A is a bacterial metabolite originally isolated from S. resistomycificus strain 2A-327. It inhibits aflatoxin production by A. parasiticus without affecting fungal growth (IC50s = 0.25 and 1.6 μM, respectively). Blasticidin A also decreases ribosomal protein levels and inhibits protein synthesis in S. cerevisiae.
T8680 FIBROBLAST GROWTH FACTOR, BASIC, HUMAN

FIBROBLAST GROWTH FACTOR, BASIC, HUMAN 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T8680,CAS号为 62031-54-3。
T81593 Osteoblast-Adhesive Peptide

Osteoblast-Adhesive Peptide是一种促进成骨细胞黏附的多肽,用于生物材料的化学修饰,具有牙科和骨科领域的潜在应用价值。
T37819 Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. It also shares sequence homology with the known neuropeptides neuromedin C , bombesin , neuromedin K , substance K , substance P , physalaemin, and eledoisin. aFGF (102-111) corresponds to amino acid residues 102-111 of the fulllength pept...
T18330 MC-Val-Cit-PAB-vinblastine

Others Others
MC-Val-Cit-PAB-vinblastine is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), featuring vinblastine (a microtubule protein inhibitor) connected through the MC-Val-Cit-PAB ADC linker.
T76321 Brain Derived Basic Fibroblast Growth Factor (1-24)

Brain Derived BasicFibroblast Growth Factor(1-24) (FGF basic 1-24) 是一种合成肽,表现出抗细菌和抗HBV 的活性。Brain Derived BasicFibroblast Growth Factor(1-24) 可用于感染性疾病和免疫性疾病的研究。
T37820 Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)

Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF. bFGF is a peptide produced in bovine brain that is protective in a rat model of pressure-induced retinal ischemia. bFGF (1-24) corresponds to amino acid residues 1-24 of the full length peptide.
T1880 P7C3

Others Others
P7C3 是一种 aminopropyl carbazole 类化合物,具有口服活性,可透过血脑屏障,具有神经保护作用。它可用于神经退行性疾病,如帕金森病的研究。
T20674 Kitazine

Ritacin-P,Ricide,EBP,Ritacin P

Kitazine is an organophosphorus chemical fungicide. It is mainly used to control rice blast and has a certain effect on rice Sclerotinia sclerotiorum, sheath blight, corn leaf spot, and spot disease.
T78576 Orysastrobin

Orysastrobin为一种QoI类杀菌剂,针对水稻叶瘟、穗瘟及纹枯病均展现出卓越防治效能。
T82025 Isotianil

Isotianil 是植物防御诱导剂,无直接抗菌效果,主要通过激活植物的典型防御反应来发挥作用。该化合物用于作为植物保护剂,防治稻瘟病。
T37865 9(S)-HOTrE

9(S)-HOTrE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on α-linolenic acid. 9(S)-HOTrE is predominantly localized in cellular ester lipids of Glechoma hederacea leaves and is partially released during artificial dehydration. The biological role of 9(S)-HOTrE in G. hederacea leaves is still undetermined, but it may play a role in natural senescence. 9(S)-HOTrE is an inhibitor of spore germination and germ tube elongation of rice blast fungus with ED50 valu...

化合物

Kevetrin hydrochloride
Cat.No: T3184
Synonym: Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride
Target: Mdm2, p53
Epiblastin A
Cat.No: T8987
Synonym:
Target: Casein Kinase
Vinblastine
Cat.No: T6721
Synonym:
Target: Microtubule Associated, AChR
Reblastatin
Cat.No: T125427
Synonym:
Target:
4-Desacetylvinblastine hydrazide
Cat.No: T29434
Synonym: DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide
Target:
Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)
Cat.No: T37595
Synonym:
Target:
Blasticidin A
Cat.No: T35769
Synonym:
Target:
FIBROBLAST GROWTH FACTOR, BASIC, HUMAN
Cat.No: T8680
Synonym:
Target:
Osteoblast-Adhesive Peptide
Cat.No: T81593
Synonym:
Target:
Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)
Cat.No: T37819
Synonym:
Target:
MC-Val-Cit-PAB-vinblastine
Cat.No: T18330
Synonym:
Target: Others
Brain Derived Basic Fibroblast Growth Factor (1-24)
Cat.No: T76321
Synonym:
Target:
Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)
Cat.No: T37820
Synonym:
Target:
P7C3
Cat.No: T1880
Synonym:
Target: Others
Kitazine
Cat.No: T20674
Synonym: Ritacin-P,Ricide,EBP,Ritacin P
Target:
Orysastrobin
Cat.No: T78576
Synonym:
Target:
Isotianil
Cat.No: T82025
Synonym:
Target:
9(S)-HOTrE
Cat.No: T37865
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T1668 Vinblastine sulfate

硫酸长春碱,NSC49842,Vincaleukoblastine sulfate salt

Microtubule Associated; AChR; Autophagy Autophagy; Cytoskeletal Signaling; Neuroscience
Vinblastine sulfate (Vincaleukoblastine sulfate salt) 是对各种癌症类型有细胞毒性的生物碱。 它可以抑制微管的形成,也可以抑制 nAChR,IC50值为8.9 μM。
T64911 Blasticidin S HCl

Antibiotic Microbiology/Virology
Blasticidin S HCl 是从 Streptomyces griseochromogenes 中分离的肽基核苷类抗生素 (antibiotic),主要通过干扰核糖体中肽键的形成从而抑制原核细胞和真核细胞蛋白的合成。
T3022 Anhydrovinblastine

脱水长春碱,3',4'-Anhydrovinblastine

Others Others
3',4'-Anhydrovinblastine (3',4'-Anhydrovinblastine) 是一种提取自Catharanthus roseus 叶片的单萜吲哚生物碱。
TSP-41077145 Podoblastin A (D-mannitol)

Podoblastin A (D-mannitol) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 TSP-41077145。
T2762 Kasugamycin hydrochloride

Kasumin,盐酸春雷霉素

Antibacterial; Antibiotic; Antifungal Microbiology/Virology
Kasugamycin hydrochloride (Kasumin) 是一种能结合 30s 和 70s 核糖体,但不能结合 50s 亚基的抗生素。它模拟 mRNA 核苷酸以破坏 tRNA 结合并抑制经典翻译起始。
TN4757 Peucedanocoumarin III

Others Others
Peucedanocoumarin Ⅲ can induce rice resistance to blast disease.
T20612 4,5,6,7-Tetrachlorophthalide

KF 32,KF32,Rabcide,KF-32,Fthalide

4,5,6,7-Tetrachlorophthalide is a fungicide used for the control of rice blast. It has a role as a melanin synthesis inhibitor and an antifungal agrochemical.

天然产物

Vinblastine sulfate
Cat.No: T1668
Synonym: 硫酸长春碱,NSC49842,Vincaleukoblastine sulfate salt
Target: Microtubule Associated, AChR, Autophagy
Blasticidin S HCl
Cat.No: T64911
Synonym:
Target: Antibiotic
Anhydrovinblastine
Cat.No: T3022
Synonym: 脱水长春碱,3',4'-Anhydrovinblastine
Target: Others
Podoblastin A (D-mannitol)
Cat.No: TSP-41077145
Synonym:
Target:
Kasugamycin hydrochloride
Cat.No: T2762
Synonym: Kasumin,盐酸春雷霉素
Target: Antibacterial, Antibiotic, Antifungal
Peucedanocoumarin III
Cat.No: TN4757
Synonym:
Target: Others
4,5,6,7-Tetrachlorophthalide
Cat.No: T20612
Synonym: KF 32,KF32,Rabcide,KF-32,Fthalide
Target:
Cat. No. Product Name Species Expression System
TMPY-03947 CD48 Protein, Human, Recombinant (hFc)

BLAST,BLAST1,SLAMF2,hCD48,mCD48,Blast<...

Human HEK293 Cells
CD48 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is P09326-1.
TMPY-01372 CD48 Protein, Mouse, Recombinant (His)

MEM-102,BLAST-1,Bcm-1,CD48 molecule,AW610730,BL...

Mouse HEK293 Cells
CD48 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.7 kDa and the accession number is P18181.
TMPY-04208 CD48 Protein, Mouse, Recombinant (hFc)

MEM-102,Sgp-60,BLAST,AI449234,BLAST1,Bcm-1...

Mouse HEK293 Cells
CD48 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49 kDa and the accession number is Q18PH8.
TMPY-06299 CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated

CD48 molecule,Blast-1,hCD48,BCM1,MEM-102,mCD48,SLAM...

Human HEK293 Cells
CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 50.88 kDa and the accession number is P09326-1.
TMPY-00712 CD48 Protein, Human, Recombinant (His)

MEM-102,SLAMF2,BLAST,Blast-1,BLAST

Human HEK293 Cells
CD48 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.8 kDa and the accession number is P09326-1.
TMPY-06283 CD48 Protein, Human, Recombinant (His & Avi), Biotinylated

SLAMF2,BLAST,mCD48,hCD48,Blast-1,MEM-102,<...

Human HEK293 Cells
CD48 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.60 kDa and the accession number is P09326-1.
TMPY-06184 CD48 Protein, Mouse, Recombinant (His), Biotinylated

MEM-102,Bcm-1,AI449234,BCM1,Sgp-60,CD48 molecule,BLAST

Mouse HEK293 Cells
CD48 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.7 kDa and the accession number is P18181.
TMPJ-00130 SLAMF2 Protein, Human, Recombinant (hFc & His)

Leukocyte antigen MEM-102,CD48 antigen,CD48,BCM1 surface ant...

Human HEK293 Cells
CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cel...
TMPY-02293 CD23 Protein, Human, Recombinant (His)

MGC40078,CLEC6,MCL,BLAST-2,CD23A,IGEBF,FCE2,MPCL,CL...

Human HEK293 Cells
CD23 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.2 kDa and the accession number is P06734-1.
TMPJ-00128 SLAMF2 Protein, Mouse, Recombinant (His)

BCM1,SLAMF2,CD48,BLAST1,SLAM Family Member 2

Mouse HEK293 Cells
CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. Among dendritic cells (DC), CD48 is selectively expressed on circulating myeloid DC and resident bone marrow and thymus DC. CD2, 2B4, and heparan sulfate function as CD48 ligands. CD48 is competent to transduce signals and can also trigger signaling through CD2 or 2B4. C...
TMPJ-00579 Ameloblastin Protein, Human, Recombinant (His)

AMBN,Ameloblastin

Human HEK293 Cells
Ameloblastin (AMBN) is a member of the Ameloblastin family. AMBN is a secreted protein and is specially expressed in ameloblast, localizing to the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel Mutations of this protein may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. Ameloblastin may play an important role in the formation and mineralization of the enamel matrix. Biochemically, it is classified as an int...
TMPY-01586 ACPL2 Protein, Human, Recombinant (His)

ACPL2,UNQ37/PRO76,FLJ23751

Human HEK293 Cells
acid phosphatase-like protein 2, also known as ACPL2, is a secreted protein which belongs to thehistidine acid phosphatase family. A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological signal sequence trap in yeast cells was utilized to identify cDNA clones encoding putative secreted proteins. A second strategy utilized various algorithms that rec...

重组蛋白

CD48 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03947
Species: Human
Expression System: HEK293 Cells
CD48 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01372
Species: Mouse
Expression System: HEK293 Cells
CD48 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-04208
Species: Mouse
Expression System: HEK293 Cells
CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06299
Species: Human
Expression System: HEK293 Cells
CD48 Protein, Human, Recombinant (His)
Cat.No: TMPY-00712
Species: Human
Expression System: HEK293 Cells
CD48 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06283
Species: Human
Expression System: HEK293 Cells
CD48 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-06184
Species: Mouse
Expression System: HEK293 Cells
SLAMF2 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00130
Species: Human
Expression System: HEK293 Cells
CD23 Protein, Human, Recombinant (His)
Cat.No: TMPY-02293
Species: Human
Expression System: HEK293 Cells
SLAMF2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00128
Species: Mouse
Expression System: HEK293 Cells
Ameloblastin Protein, Human, Recombinant (His)
Cat.No: TMPJ-00579
Species: Human
Expression System: HEK293 Cells
ACPL2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01586
Species: Human
Expression System: HEK293 Cells
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