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59

抑制剂 & 化合物

1

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Cat. No.	Product Name	Target	Signaling Pathways
T29719	AGM 1883 AGM1883,AGM-1883
	AGM 1883 is a biochemical.
T23753	Arctigenin mustard AgM
	Arctigenin mustard is a tumor-growth inhibiting substance.
T17110	TNP-470 AGM-1470	Others	Others
	TNP-470 is a methionine aminopeptidase-2 inhibitor. TNP-470 is also an angiogenesis inhibitor.
TP1560	c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm
	c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm a highly efficient, selective and short-acting peptide V2 receptor agonist (V2R), with EC50s of hV2R and rV2R being 0.25 and 0.05 nM, respectively.
TP1530L	YRGDS Fibronectin Fragment acetate YRGDS Fibronectin Fragment acetate(134282-68-1 free base)	Others	Others
	YRGDS Fibronectin Fragment acetate (YRGDS Fibronectin Fragment acetate (134282-68-1 free base))(134282-68-1 free base) 是一种纤连蛋白片段乙酸酯，是一种粘附肽，对凝血酶刺激的血小板具有很强的结合亲和力。它是由序列组成的 RGD。
T75888	PKA Inhibitor Fragment (6-22) amide TFA PKI-(6-22)-amide TFA,PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base)	PKA	Tyrosine Kinase/Adaptors
	PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) 是抑制高效 cAMP 依赖性蛋白激酶 A (PKA)抑制剂(Ki：2.8 nM)。PKA Inhibitor Fragment (6-22) amide TFA 可逆转小鼠低水平的吗啡缓解疼痛的作用。
TP2298L	transferrin fragment acetate	Others	Others
	transferrin fragment acetate 是动物血清中主要的铁结合蛋白，其铁结合位点和性质类似于乳铁蛋白1。
T21674L	PKA inhibitor fragment (6-22) amide Acetate PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base)	PKA	Tyrosine Kinase/Adaptors
	PKA inhibitor fragment (6-22) amide Acetate 是一种通过结合底物位点选择性抑制PKA 活性的合成肽(IC50 < 2 nM)。
TP1555L1	Fibronectin Active Fragment Control acetate Fibronectin Active Fragment Control acetate(97461-84-2 Free base)
	Fibronectin Active Fragment Control acetate 是纤连蛋白的活性片段，这是一种糖蛋白。
T76555	Rabies Virus Matrix Protein Fragment(RV-MAT)
	Rabies VirusMatrix ProteinFragment (RV-MAT)为多肽类化合物，靶向细胞表面乙酰胆碱受体(AChR)。
TP2216	alpha-1 antitrypsin fragment 235-243 [Homo sapiens]/[Papio hamadryas]/[Cercopithecus aethiops]	Others	Others
	Protease inhibitor
TP1056	Phosphorylase Kinase β-Subunit Fragment (420-436) Phosphorylase Kinase β-Subunit(420-436),Phosphorylase Kinase β-Subunit Fragment 420-436
	Phosphorylase Kinase β-Subunit Fragment (420-436) is a peptide fragment (430-436) derived from the β-Subunit of phosphorylase kinase. Phosphorylase kinase, a serine/threonine-specific protein kinase, plays a crucial role in the activation of glycogen phosphorylase for the release of glucose-1-phosphate from glycogen[1].
TP2269	MAP kinase fragment [Multiple species]	Others	Others
	This Mitogen-activated protein kinase (MAP kinase) fragment has a peptide sequence of Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu. The MAP kinases are serine/threonine-specific protein kinases belonging to the CMGC (CDK/MAPK/GSK3/CLK) kinase group.
T32520	Lac repressor fragment 33-38
	Lac repressor fragment 33-38 Lys-Arg-Glu-Lys-Val fragment from lac repressor.
TP2301	type II collagen fragment	Others	Others
	Type II collagen is composed of a triple helix of three identical α chains. These molecules associate to form a fibril that is stabilized by intermolecular crosslinks1. Damage to the fibrillar meshwork, made up of primarily type II collagen (z 90–95%), ma
TP1530	YRGDS Fibronectin Fragment
	This is a fibronectin fragment, an adhesion peptide that displays strong binding affinity to thrombin-stimulated platelets. It is RGD consisting of sequence.
T82403	Fibronectin Type III Connecting Segment Fragment 1-25
	Fibronectin Type III Connecting Segment Fragment 1-25，一种多肽，主要作用于黑色素瘤细胞的粘附，并在鸡的周围神经系统发育中扮演关键角色。
T22868	Influenza A virus fragment	Others	Others
	Influenza A virus fragment has the RNA sequence of Leu-Lys-Phe-Ala-Phe-Ser-Met-Met.
T76240	Urinary Trypsin Inhibitor Fragment
	Urinary Trypsin Inhibitor Fragment，一种通过蛋白水解生成的尿胰蛋白酶抑制剂片段，能通过有限蛋白水解抑制肿瘤细胞侵袭。
TP2255	heparin cofactor II precursor fragment [Homo sapiens]	Others	Others
	Heparin cofactor II precursor fragment [Homo sapiens] is a peptide with the sequence H2N-Tyr-Glu-Ile-Thr-Thr-Ile-His-Asn-Leu-Phe-Arg-OH, MW=1406.58.
TP2256	heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]	Others	Others
	Heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens] is a peptide with the sequence H2N-Phe-Thr-Val-Asp-Arg- Pro-Phe-Leu-Phe-Leu-Ile-Tyr-Glu-His-Arg-OH, MW=1953.25.
T80046	Myosin H Chain Fragment, mouse acetate
	MyosinH Chain Fragment, mouse acetate salt，一种α-肌球蛋白重链肽的肽段，用于诱导实验性自身免疫性心肌炎(EAM)的小鼠模型。
T76527	Hepatitis B Virus Receptor Binding Fragment
	Hepatitis B Virus Receptor Binding Fragment（hepatitis B peptide 4980）为一合成肽类似物，特异性结合Hep G2细胞。基于病毒中和粘附阻断理念，此Fragment可望激发保护性抗体生成，展现作为免疫原的巨大潜力。
TP2259	immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]	Others	Others
	Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule
T78571	Albiglutide fragment TFA GLP-1-Gly8 TFA,GLP-1 (7-36) analog TFA
	Albiglutide fragment (GLP-1 (7-36) analog) TFA为Albiglutide活性片段，代表胰高血糖素样肽-1(GLP-1)模拟物，属长效GLP-1受体激动剂。由GLP-1二聚体抗DPP-4特性与人白蛋白基因融合而成，本化合物在降低糖化血红蛋白(A1C)方面表现显著，主要应用于2型糖尿病(T2D)的相关研究。
T38743	Scrambled TRAP Fragment
	Scrambled TRAP Fragment is a variant of the TRAP Fragment compound, characterized by its random amino acid sequence. It is typically employed as a negative control due to its similarity in composition to the active fragment.
T81732	Myosin light chain kinase fragment 11-19 amide MLCK(11-19) amide
	Myosinlight chain kinase fragment 11-19 amide (MLCK(11-19) amide) 为MLCK专一性多肽抑制剂，具抑制低渗透压刺激下Ca2+入细胞的能力，并可应用于人类宫颈癌研究。
TP2281	p53 tumor suppressor fragment	Others	Others
	p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where i
TP1555	Fibronectin Active Fragment Control
	Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin
T78375	Myosin H Chain Fragment, mouse
	MyosinH Chain Fragment, mouse, 来自α-肌球蛋白重链肽的片段，旨在诱导实验性自身免疫性心肌炎(EAM)小鼠模型。
TP2260	Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens]	Others	Others
	Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] is a fragment (Gly-Val-Ala-Leu-His-Arg-Pro-Asp-Val-Tyr-Leu-Leu-Pro-Pro-Ala-Arg) on the human immunoglobulin micro heavy chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cell
TP2291	signal transducer and activator of transcription 6 fragment	Others	Others
	The signal transducer and activator of transcription 6 fragments is a peptide with the sequence H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH, MW= 1152.3.
T79149	Magmas-IN-1	Others	Others
	Magmas-IN-1（compound 9）为针对Magmas的小分子抑制剂（SMMI），后者是线粒体相关粒细胞-巨噬细胞集落刺激因子（GM-CSF）的信号分子，并参与骨髓细胞的GM-CSF诱导基因表达。Magmas-IN-1作用于Magmas，进而调控线粒体功能，并在4 μM浓度下可显著抑制酵母细胞的增殖。
TP2234	coagulation factor II (thrombin) B chain fragment [Homo sapiens]	Others	Others
	Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a serine protease that converts soluble
TP1120	Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP
	Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visual pigment Binding Protein peptide (IRBP 161-180) and can induce post-uv
TP2217	alpha-1 antitrypsin fragment	Others	Others
	Alpha-1 antitrypsin (A1AT) is known as a serum trypsin inhibitor and is a protease inhibitor belonging to the serpin superfamily. Alpha-1 antitrypsin is a single-chain glycoprotein consisting of 394 amino acids in the mature form and exhibits a number of
T80253	S3 Fragment
	S3 Fragment 是具有生物活性的肽，含有 ADF/cofilin 的特异性 N-端磷酸化位点，即 LIM 激酶（LIMK）的靶点。LIMK1 通过在 ADF/cofilin 的丝氨酸 3 位磷酸化来失活该蛋白，是肌动蛋白细胞骨架重要调控因子。该肽段包含 ADF/cofilin 丝氨酸 3 位点，作为 LIMK1 的有效竞争性抑制剂而被广泛研究。
TP2299	tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]	Others	Others
	Tumor protein p53 binding protein (53BP1) has been identified in a yeast two-hybrid screen as a protein that interacts with the central DNA–binding domain of p532. Similar to breast cancer susceptibility gene 13, 4 (BRCA1; 53BP1 enhances p53-dependent tra
TP2287	Rac GTPase fragment	Others	Others
	Rac GTPase fragment is a peptide with the sequence H2N-Val-Phe-Asp-Glu-Ala-Ile-Arg-Ala-Val-OH, MW= 1019.15. Rac is a subfamily of the Rho family of GTPases, small signaling G proteins (more specifically a GTPase).
TP2248	ferritin heavy chain fragment [Multiple species]	Others	Others
	Ferritin is a protein of 450 kDa consisting of 24 subunits that is present in every cell type. Invertebrates, these subunits are both the light (L) and the heavy (H) type with an apparent molecular weight of 19 kDA or 21 kDA respectively. The ferritin fou
T76566	Fsh receptor-binding inhibitor fragment(bi-10)
	FSHreceptor-binding inhibitor fragment(bi-10) 是一种有效的 FSH 拮抗剂。FSHreceptor-binding inhibitor fragment(bi-10) 阻断 FSH 与 FSHR 的结合，并在受体水平上改变 FSH 的作用。FSHreceptor-binding inhibitor fragment(bi-10) 导致小鼠排卵抑制和卵泡闭锁。FSHreceptor-binding inhibitor fragment(bi-10) 通过下调卵巢中 FSHR 和 ERβ的过度表达来抑制卵巢癌发生。
TP2298	transferrin fragment	Others	Others
	Transferrin is the principal iron-binding protein in animal serum and is analogous in its iron-binding site and properties to lactoferrin1. Human transferrin is a single-chain glycoprotein of molecular weight near 80,000. The molecule is arranged in two l
T71495	Monofluoromethylagmatine
	Monofluoromethylagmatine is an arginine decarboxylase inhibitor.
T131457	Entandrophragmin
	Entandrophragmin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131457。
T22865	immunoglobulin light chain variable region fragment [Homo sapiens]	Others	Others
	Immunoglobulin light chain variable region fragment [Homo sapiens] is a fragment (Phe-Thr-Leu-Lys-Ile-Ser-Arg) on the variable region of the human immunoglobulin light chain.
TP2237	Cytochrome c fragment (93-108)	Others	Others
	Cytochrome c fragment (93-108) is a peptide from Cytochrome c, which is a small heme protein found loosely associated with the inner membrane of the mitochondrion. Cytochromes c from certain eukaryotes, including plants and fungi but not higher animals, contains methylated lysine residues at specific positions1. Cytochrome c is a required cofactor for Apaf-1 function2.
T22575	Angiotensin Fragment 1-7 (acetate)	Others	Others
	Angiotensin Fragment 1-7 is a type 1 angiotensin II receptor agonist. In the renin-angiotensin system, angiotensin I is cleaved by the angiotensin-converting enzyme to form angiotensin II, which has effects on fluid and electrolyte, as well as homeostasis
T82060	Interleukin-6 fragment (human)
	Interleukin-6 fragment (human) 是一种多效性细胞因子，由淋巴细胞及非淋巴细胞产生。该分子的编码基因位于人类第7号染色体，长度大约为5 kb。Interleukin-6 fragment (human) 在免疫响应、急性相应、炎症过程、癌症治疗及血液造血方面均有重要的潜在应用。
TQ0004	Albiglutide Fragment	Others	Others
	Albiglutide fragment is a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).
T76458	P34cdc2 Kinase Fragment
	P34cdc2 Kinase Fragment，与酵母有丝分裂中DNA复制的完整度相关，并能磷酸化丝裂原激活蛋白MAP2，进而调节爪蟾卵母细胞减数分裂中的微管聚合活性。

化合物

Cat.No: T29719

Synonym: AGM1883,AGM-1883

Arctigenin mustard

Cat.No: T23753

Synonym: AgM

Cat.No: T17110

Synonym: AGM-1470

Target: Others

c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm

Cat.No: TP1560

YRGDS Fibronectin Fragment acetate

Cat.No: TP1530L

Synonym: YRGDS Fibronectin Fragment acetate(134282-68-1 free base)

Target: Others

PKA Inhibitor Fragment (6-22) amide TFA

Cat.No: T75888

Synonym: PKI-(6-22)-amide TFA,PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base)

Target: PKA

transferrin fragment acetate

Cat.No: TP2298L

Target: Others

PKA inhibitor fragment (6-22) amide Acetate

Cat.No: T21674L

Synonym: PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base)

Target: PKA

Fibronectin Active Fragment Control acetate

Cat.No: TP1555L1

Synonym: Fibronectin Active Fragment Control acetate(97461-84-2 Free base)

Rabies Virus Matrix Protein Fragment(RV-MAT)

Cat.No: T76555

alpha-1 antitrypsin fragment 235-243 [Homo sapiens]/[Papio hamadryas]/[Cercopithecus aethiops]

Cat.No: TP2216

Target: Others

Phosphorylase Kinase β-Subunit Fragment (420-436)

Cat.No: TP1056

Synonym: Phosphorylase Kinase β-Subunit(420-436),Phosphorylase Kinase β-Subunit Fragment 420-436

MAP kinase fragment [Multiple species]

Cat.No: TP2269

Target: Others

Lac repressor fragment 33-38

Cat.No: T32520

type II collagen fragment

Cat.No: TP2301

Target: Others

YRGDS Fibronectin Fragment

Cat.No: TP1530

Fibronectin Type III Connecting Segment Fragment 1-25

Cat.No: T82403

Influenza A virus fragment

Cat.No: T22868

Target: Others

Urinary Trypsin Inhibitor Fragment

Cat.No: T76240

heparin cofactor II precursor fragment [Homo sapiens]

Cat.No: TP2255

Target: Others

heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]

Cat.No: TP2256

Target: Others

Myosin H Chain Fragment, mouse acetate

Cat.No: T80046

Hepatitis B Virus Receptor Binding Fragment

Cat.No: T76527

immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]

Cat.No: TP2259

Target: Others

Albiglutide fragment TFA

Cat.No: T78571

Synonym: GLP-1-Gly8 TFA,GLP-1 (7-36) analog TFA

Scrambled TRAP Fragment

Cat.No: T38743

Myosin light chain kinase fragment 11-19 amide

Cat.No: T81732

Synonym: MLCK(11-19) amide

p53 tumor suppressor fragment

Cat.No: TP2281

Target: Others

Fibronectin Active Fragment Control

Cat.No: TP1555

Myosin H Chain Fragment, mouse

Cat.No: T78375

Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens]

Cat.No: TP2260

Target: Others

signal transducer and activator of transcription 6 fragment

Cat.No: TP2291

Target: Others

Cat.No: T79149

Target: Others

coagulation factor II (thrombin) B chain fragment [Homo sapiens]

Cat.No: TP2234

Target: Others

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)

Cat.No: TP1120

Synonym: IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP

alpha-1 antitrypsin fragment

Cat.No: TP2217

Target: Others

Cat.No: T80253

tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]

Cat.No: TP2299

Target: Others

Rac GTPase fragment

Cat.No: TP2287

Target: Others

ferritin heavy chain fragment [Multiple species]

Cat.No: TP2248

Target: Others

Fsh receptor-binding inhibitor fragment(bi-10)

Cat.No: T76566

transferrin fragment

Cat.No: TP2298

Target: Others

Monofluoromethylagmatine

Cat.No: T71495

Entandrophragmin

Cat.No: T131457

immunoglobulin light chain variable region fragment [Homo sapiens]

Cat.No: T22865

Target: Others

Cytochrome c fragment (93-108)

Cat.No: TP2237

Target: Others

Angiotensin Fragment 1-7 (acetate)

Cat.No: T22575

Target: Others

Interleukin-6 fragment (human)

Cat.No: T82060

Albiglutide Fragment

Cat.No: TQ0004

Target: Others

P34cdc2 Kinase Fragment

Cat.No: T76458

Cat. No.	Product Name	Target	Signaling Pathways
T4808	Agmatine sulfate Agmatine sulfate salt,硫酸胍基丁胺	Endogenous Metabolite; NO Synthase; Imidazoline Receptor	Immunology/Inflammation; Metabolism; Neuroscience
	Agmatine sulfate (Agmatine sulfate salt) 是咪唑啉受体的内源性激动剂和一氧化氮合酶抑制剂。它靶向神经递质系统，离子通道和一氧化氮合成。

天然产物

Agmatine sulfate

Cat.No: T4808

Synonym: Agmatine sulfate salt,硫酸胍基丁胺

Target: Endogenous Metabolite, NO Synthase, Imidazoline Receptor

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