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Search Results for " asl "

Targets Recommended: Fas/FasL

8

抑制剂 & 化合物

8

天然产物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T30159	ASL-7003 ASL 7003,ASL7003,
	ASL-7003 is a dopamine analog with cardian stimulating properties.
T3575	Acecainide hydrochloride ASL 601,NAPA	Others	Others
	Acecainide hydrochloride (NAPA) 是 PROCAINAMIDE 的主要代谢物。其抗心律失常作用可能导致肾衰竭时的心脏毒性。
T20458	Aspirin DL-lysine DL-Lysine acetylsalicylic acid salt,Aspegic,ASL,Aspisol
	Aspirin DL-lysine is a non-steroidal anti-inflammatory drug. It also may inhibit cancer growth. Aspirin DL-lysine is a water-soluble, injectable aspirin derivative.
T81852	Maslimomab
	Maslimomab为针对T细胞受体的鼠源性单克隆抗体，亦作为免疫抑制剂。
T80906	TYVPANASL TFA
	TYVPANASL TFA，一种由HER2/neu的9个氨基酸组成，可结合MHC I并与CD8 T细胞表位相关的化合物。该化合物可用于制备J-LEAPS疫苗。
T80907	TYVPANASL
	TYVPANASL为由HER2/neu的9个氨基酸组成的MHC I结合CD8 T细胞表位，可用于制备J-LEAPS疫苗。
T37039	Betulinic Aldehyde oxime
	Betulinic aldehyde oxime is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It is active againstE. aerogenes,E. coli,E. faecalis,P. aeruginosa,S. aureus, andC. albicans, as well asL. donovaniamastigotes, when used at a concentration of 50 μM.1,2Betulinic aldehyde oxime (50 μM) is cytotoxic to Huh7 hepatocellular carcinoma cells.2
T82972	Argininosuccinic acid disodium	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Argininosuccinic acid disodium 在尿素循环的第四步起关键作用，由ASL(精氨酸琥珀酸裂解酶)催化裂解生成精氨酸和富马酸。此外，该化合物能够降低GSH(还原型谷胱甘肽)浓度，并提升大脑皮层与纹状体中的活性氧产生。Argininosuccinic acid disodium 还可能导致脂质过氧化和蛋白质氧化，并在发育中的大鼠脑内触发氧化应激。

化合物

Cat.No: T30159

Synonym: ASL 7003,ASL7003,

Acecainide hydrochloride

Cat.No: T3575

Synonym: ASL 601,NAPA

Target: Others

Aspirin DL-lysine

Cat.No: T20458

Synonym: DL-Lysine acetylsalicylic acid salt,Aspegic,ASL,Aspisol

Cat.No: T81852

Cat.No: T80906

Cat.No: T80907

Betulinic Aldehyde oxime

Cat.No: T37039

Argininosuccinic acid disodium

Cat.No: T82972

Target: Reactive Oxygen Species

Cat. No.	Product Name	Target	Signaling Pathways
T1644	Dopamine hydrochloride 盐酸多巴胺,Dopamine HCl,ASL279	Ferroptosis; Dopamine Receptor; 5-HT Receptor; Endogenous Metabolite	Apoptosis; GPCR/G Protein; Metabolism; Neuroscience
	Dopamine hydrochloride (ASL279) 是在脑黑质、脑腹侧被盖区和下丘脑中产生的一种天然儿茶酚胺，由二羟基苯丙氨酸脱羧形成，是去甲肾上腺素和肾上腺素的前体。它通过 D2 多巴胺受体来诱导 VEGFR2 的内吞作用，有促进血管生成活性。
TN2130	Manghaslin 槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside	AChE; Glucosidase	Metabolism; Neuroscience
	Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) 是具有抗炎活性的黄酮苷，对 AChE 具有抑制活性，IC50=94.92 µM。
TN7129	Methyl maslinate 马斯里酸甲酯,Maslinic acid methyl ester,Crategolic acid methyl ester	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Methyl maslinate (Maslinic acid methyl ester) 是一种具有强心和抗心律失常特性的 β-肾上腺素受体拮抗剂。Methyl maslinate 可用于高血压研究。
T3772	Maslinic acid 2α-Hydroxyoleanoic Acid,山楂酸,2α-Hydroxyoleanolic acid,Crategolic acid	NF-κB; HIV Protease; DNA/RNA Synthesis; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Maslinic acid (Crategolic acid) 是一种 DNA 聚合酶 B 抑制剂，抑制 NF-κB p65的 DNA 结合活性并消除 IκB-α磷酸化。
TN6163	3-O-cis-p-Coumaroylmaslinic acid
	3-beta-O-(trans-p-Coumaroyl)maslinic acid shows antimicrobial activity on Gram-positive bacteria and yeasts.
TN6148	3-O-trans-p-Coumaroylmaslinic acid
	3-beta-O-(trans-p-Coumaroyl)maslinic acid is a DNA polymerase B" inhibitor. It shows antimicrobial activity on Gram-positive bacteria and yeasts.
TN5558	Jaslanceoside B
	Jaslanceoside B 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5558，CAS号为 188300-82-5。
T37977	Succinyladenosine
	Succinyladenosine is a biochemical marker of adenylosuccinase (ASL) deficiency. It is formed through the dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase [1].

天然产物

Dopamine hydrochloride

Cat.No: T1644

Synonym: 盐酸多巴胺,Dopamine HCl,ASL279

Target: Ferroptosis, Dopamine Receptor, 5-HT Receptor, Endogenous Metabolite

Cat.No: TN2130

Synonym: 槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside

Target: AChE, Glucosidase

Methyl maslinate

Cat.No: TN7129

Synonym: 马斯里酸甲酯,Maslinic acid methyl ester,Crategolic acid methyl ester

Target: Adrenergic Receptor

Cat.No: T3772

Synonym: 2α-Hydroxyoleanoic Acid,山楂酸,2α-Hydroxyoleanolic acid,Crategolic acid

Target: NF-κB, HIV Protease, DNA/RNA Synthesis, Antibacterial

3-O-cis-p-Coumaroylmaslinic acid

Cat.No: TN6163

3-O-trans-p-Coumaroylmaslinic acid

Cat.No: TN6148

Jaslanceoside B

Cat.No: TN5558

Succinyladenosine

Cat.No: T37977

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03172	Argininosuccinate lyase Protein, Human, Recombinant (His & GST) ASAL,argininosuccinate lyase,ASL	Human	Baculovirus Insect Cells
	The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established role in numerous physiological and pathological processes, but the specific cellular sources of NO in disease pathogenesis remain unclear, preventing the implementation of NO-related therapy. Argininosuccinate lyase (ASL) is the only enzyme able to produce arginine, the substrate ...
TMPY-02552	Adenylosuccinate Lyase Protein, Human, Recombinant (His) ASL,adenylosuccinate lyase,ASASE,AMPS	Human	E. coli
	Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine nucleotide cycle. The two substates of adenylosuccinate lyase (ADSL) are dephosphorylated derivatives of SAICA ribotide (SAICAR) and adenylosuccinate (S-AMP), which catalyzes an important reaction in the de novo pathway of purine biosynthesis. ADSL catalyzes two distinct reactions in the synthesis of purine nucleotide...
TMPH-02454	Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (E. coli, His)	MeV	E. coli
	Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is B8PZP3.
TMPH-00848	OASL Protein, Human, Recombinant (His)	Human	E. coli
	Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. OASL Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 65.1 kDa and the accession number is Q15646.
TMPH-02453	Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His)	MeV	Baculovirus Insect Cells
	Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 46.9 kDa and the accession number is B8PZP3.
TMPH-02452	Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His)	MeV	E. coli
	Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His) is expressed in E. coli expression system with N-10xHis and C-Avi tag. The predicted molecular weight is 61.8 kDa and the accession number is P69356.
TMPH-02527	ASS1 Protein, Mouse, Recombinant (His & Myc) Ass,Citrulline--aspartate ligase,Ass1,Argininosuccinate synt...	Mouse	E. coli
	One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. ASS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 5...

重组蛋白

Argininosuccinate lyase Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03172

Species: Human

Expression System: Baculovirus Insect Cells

Adenylosuccinate Lyase Protein, Human, Recombinant (His)

Cat.No: TMPY-02552

Species: Human

Expression System: E. coli

Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (E. coli, His)

Cat.No: TMPH-02454

Species: MeV

Expression System: E. coli

OASL Protein, Human, Recombinant (His)

Cat.No: TMPH-00848

Species: Human

Expression System: E. coli

Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His)

Cat.No: TMPH-02453

Species: MeV

Expression System: Baculovirus Insect Cells

Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His)

Cat.No: TMPH-02452

Species: MeV

Expression System: E. coli

ASS1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02527

Species: Mouse

Expression System: E. coli

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