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4

抑制剂 & 化合物

5

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T12201	Nebracetam hydrochloride WEB 1881 FU hydrochloride	AChR	Neuroscience
	Nebracetam hydrochloride (WEB 1881 FU hydrochloride) 是促智 M1-毒蕈碱的激动剂。它诱导细胞内 Ca2+ 浓度升高， EC50 为 1.59 mM。
T40413	SW157765	transporter	Metabolism
	SW157765 是一种选择性葡萄糖转运体 GLUT8（SLC2A8）抑制剂，是很多化合物的前药，以剂量依赖性方式选择性地抑制SW157765敏感细胞中荧光 2-脱氧葡萄糖（2DG）的摄取，可用于研究肺癌。
T77790	Phenylarsine oxide Oxophenylarsine
	Phenylarsine Oxide (Oxophenylarsine) 是膜透性酪氨酸磷酸酶抑制剂，IC50值为18 µM，能够刺激胰岛素抵抗性人体骨骼肌的2-脱氧葡萄糖转运。
T35683	2-deoxy-D-Glucose-13C6 2-deoxy-D-Glucose-13C6
	2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B oste...

化合物

Nebracetam hydrochloride

Cat.No: T12201

Synonym: WEB 1881 FU hydrochloride

Target: AChR

Cat.No: T40413

Target: transporter

Phenylarsine oxide

Cat.No: T77790

Synonym: Oxophenylarsine

2-deoxy-D-Glucose-13C6

Cat.No: T35683

Synonym: 2-deoxy-D-Glucose-13C6

Cat. No.	Product Name	Target	Signaling Pathways
T19117	3-Deoxyglucosone 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose	GPX; Glucagon Receptor	GPCR/G Protein; oxidation-reduction
	3-Deoxyglucosone(3-Deoxy-D-glucosone) 是美拉德反应和多元醇反应的中间体途径合成。3-Deoxyglucosone 与蛋白质氨基快速反应形成晚期糖基化末端蛋白 (AGEs)。3-Deoxyglucosone 可使谷胱甘肽过氧化物酶失活，可与低葡萄糖协同作用以增强 GLP-1 分泌，可以作为糖尿病生物学检测的标志物。
T6742	2-Deoxy-D-glucose 2-Deoxy-D-arabino-hexose,2-deoxyglucose,D-Arabino-2-deoxyhexose,Ba 2758,D-2-脱氧葡萄糖,NSC 15193,2-DG,2-脱氧-D-葡萄糖	Apoptosis; Hexokinase; HSV	Apoptosis; Metabolism; Microbiology/Virology
	2-Deoxy-D-glucose (2-DG) 是葡萄糖的类似物，是一种糖酵解抑制剂。2-Deoxy-D-glucose 具有抗病毒活性，还具有抑制细胞增殖、诱导细胞凋亡的活性。
T4514	N-Acetyl-D-Glucosamine N-乙酰-D-氨基葡萄糖,NAG,N-Acetyl-2-amino-2-deoxyglucose,Marine Sweet,N-Acetyl-2-amino-2-deoxy-D-glucose,N-乙酰氨基葡萄糖,GlcNAc	Endogenous Metabolite	Metabolism
	N-Acetyl-D-Glucosamine (NAG) 是葡萄糖的单糖衍生物。
T78496	2-Amino-2-deoxyglucose hydrochloride
	2-Amino-2-deoxyglucose hydrochloride 为盐酸己糖胺类化合物，适用于合成环丙烯修饰己糖胺衍生物（Ac4GlcNCyoc 及 Ac4GalNCyoc）。
T37232	(+)-Geodin
	(+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyglucose uptake by rat adipocytes.

天然产物

3-Deoxyglucosone

Cat.No: T19117

Synonym: 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose

Target: GPX, Glucagon Receptor

2-Deoxy-D-glucose

Cat.No: T6742

Synonym: 2-Deoxy-D-arabino-hexose,2-deoxyglucose,D-Arabino-2-deoxyhexose,Ba 2758,D-2-脱氧葡萄糖,NSC 15193,2-DG,2-脱氧-D-葡萄糖

Target: Apoptosis, Hexokinase, HSV

N-Acetyl-D-Glucosamine

Cat.No: T4514

Synonym: N-乙酰-D-氨基葡萄糖,NAG,N-Acetyl-2-amino-2-deoxyglucose,Marine Sweet,N-Acetyl-2-amino-2-deoxy-D-glucose,N-乙酰氨基葡萄糖,GlcNAc

Target: Endogenous Metabolite

2-Amino-2-deoxyglucose hydrochloride

Cat.No: T78496

Cat.No: T37232

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