抑制性免疫检查点蛋白

抑制性免疫检查点分子在维持免疫稳态中起着至关重要的作用：它们效应 T 细胞上的表达确保了效应 T 细胞反应的适当紧缩；它们在调节性 T (Treg) 细胞上的表达促进了Treg细胞的抑制功能。阻断共抑制分子已被证实可以增强宿主对各种癌症的免疫应答，在癌症治疗中表现出显著的临床效果。

Species：

Expression System：

Tag：

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPK-00622	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi) CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00622	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell ...
TMPK-00623	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00623	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell ...
TMPK-00624	CD200R1/CRTR2 Protein, Human, Recombinant (hFc) CD200R1/CRTR2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPK-00624	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell ...
TMPK-00644	CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
TMPK-00644	CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 ...
TMPK-00651	SLAMF6 Protein, Cynomolgus, Recombinant (His) SLAMF6 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPK-00651	SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobul...
TMPK-00653	B7-2 Protein, Cynomolgus, Recombinant (His) B7-2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPK-00653	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul...
TMPK-00662	PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated	Cynomolgus,Rhesus	HEK293 Cells
TMPK-00662	B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been ident...
TMPK-00688	PD-1 Protein, Canine, Recombinant (aa 25-170, hFc) PD-1 Protein, Canine, Recombinant (aa 25-170, hFc)	Canine	HEK293 Cells
TMPK-00688	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's resp...
TMPK-00733	CD200 Protein, Mouse, Recombinant (aa 31-232, His) CD200 Protein, Mouse, Recombinant (aa 31-232, His)	Mouse	HEK293 Cells
TMPK-00733	CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with...
TMPK-00813	FGL2 Protein, Mouse, Recombinant (His & Avi, Flag) FGL2 Protein, Mouse, Recombinant (His & Avi, Flag)	Mouse	HEK293 Cells
TMPK-00813	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immun...
TMPK-00814	FGL2 Protein, Mouse, Recombinant (His & Avi, Flag), Biotinylated FGL2 Protein, Mouse, Recombinant (His & Avi, Flag), Biotinylated	Mouse	HEK293 Cells
TMPK-00814	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immun...
TMPK-00875	CD96 Protein, Human, Recombinant (His & Avi), Biotinylated CD96 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00875	The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in ...
TMPK-00880	B7-2 Protein, Human, Recombinant (His & Avi) B7-2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00880	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul...
TMPK-00881	B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00881	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul...
TMPK-00882	B7-2 Protein, Human, Recombinant (hFc) B7-2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPK-00882	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul...
TMPK-00958	BTN1A1 Protein, Human, Recombinant (His & Avi) BTN1A1 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00958	Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD,BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving m...
TMPK-00968	FGL2 Protein, Human, Recombinant (His & Avi, Flag) FGL2 Protein, Human, Recombinant (His & Avi, Flag)	Human	HEK293 Cells
TMPK-00968	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immun...
TMPK-00969	FGL2 Protein, Human, Recombinant (His & Avi, Flag), Biotinylated FGL2 Protein, Human, Recombinant (His & Avi, Flag), Biotinylated	Human	HEK293 Cells
TMPK-00969	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immun...
TMPK-00970	FGL2 Protein, Human, Recombinant (hFc & Flag) FGL2 Protein, Human, Recombinant (hFc & Flag)	Human	HEK293 Cells
TMPK-00970	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immun...
TMPK-00985	FGL2 Protein, Rat, Recombinant (His & Avi, Flag), Biotinylated FGL2 Protein, Rat, Recombinant (His & Avi, Flag), Biotinylated	Rat	HEK293 Cells
TMPK-00985	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immun...