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Cat. No. Product Name Target Signaling Pathways
T0279 Metaraminol tartrate

重酒石酸间羟胺,Metaradrine tartrate,Metaraminol bitartrate

Adrenergic Receptor GPCR/G Protein; Neuroscience
Metaraminol tartrate (Metaradrine tartrate) 是一种 α-肾上腺素能 (α-adrenergic) 激动剂,是一种直接或间接影响肾上腺素受体的拟交感神经胺,其中 α 效应占主导地位,可作为血管加压剂。
T6888 Methylene Blue

亚甲蓝,methylthioninium chloride,CI-52015,Tetramethylthionine chloride,亚甲兰,Basic Blue 9

Guanylate cyclase; Microtubule Associated; NO Synthase; Parasite; Monoamine Oxidase Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Methylene Blue (Tetramethylthionine chloride) 是鸟苷酸环化酶,是单胺氧化酶 A 和 NO 合酶抑制剂。它有抗伤害感受、抗疟疾、抗抑郁和抗焦虑作用,可研究高铁血红蛋白血症、神经退行性疾病和异环磷酰胺引起的脑病。它是血管加压剂,用作色素内窥镜检查中的染料。
T0006 Methylene Blue trihydrate

碱性亚甲蓝三水合物,Methylthionine chloride,Basic blue 9,亚甲蓝三水合物,Methylene Blue

Guanylate cyclase; Microtubule Associated; NO Synthase; Parasite; Monoamine Oxidase Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Methylene Blue trihydrate (Basic blue 9) 是鸟苷酸环化酶,单胺氧化酶 A 和 NO 合酶抑制剂。它是血管加压药,在医疗中通常用作染料。它具有抗伤害感受,抗疟疾,抗抑郁和抗焦虑作用,可用于高铁血红蛋白血症,神经退行性疾病和异环磷酰胺引起的脑病的研究。
TP1927L1 d[Leu4,Lys8]-VP acetate

d[Leu4,Lys8]-VP acetate(42061-33-6 free base)

Vasopressin Receptor GPCR/G Protein
d[Leu4,Lys8]-VP acetate 是一种选择性加压素 V1b 受体激动剂。 大鼠、人和小鼠 V1b 受体的 Kis 分别为 0.16 nM、0.52 nM 和 0.1.38 nM。 d[Leu4,Lys8]-VP acetate 表现出较弱的抗利尿、血管加压和体外催产活性。
TP2082L d[Cha4]-AVP acetate(500170-27-4 free base)

Vasopressin Receptor GPCR/G Protein
d[Cha4]-AVP acetate(500170-27-4 free base) 是一种有效的选择性人血管加压素 V1B 受体激动剂(V1B、V1A、催产素和 V2 受体的 Ki 值分别为 1.2、151、240 和 750 nM)。刺激 ACTH 和皮质酮分泌,并在体内表现出微不足道的血管加压活性。
T12035 Midodrine D6 hydrochloride

盐酸米多君 D6

Others Others
Midodrine D6 hydrochloride is a vasopressor/antihypotensive agent.
T22572 Angiotensin 1/2 (1-7) amide

Others Others
Angiotensin I/II (1-7) amide is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse. Angiotensin I/II amide is an amide derivative of angiotensin II that is a powerful vasoco
T33384 Midodrine (R-isomer HCl)

ProAmatine,Midodrine,ST-1085,Gutron,Amatine

Midodrine is a vasopressor/antihypertensive agent for the treatment of symptomatic postural hypotension.
TP1927 d[Leu4,Lys8]-VP

Selective vasopressin V1B receptor agonist (Ki values are 0.16, 64, 100 and 3800 nM for V1B, oxytocin, V2 and V1A receptors respectively). Displays weak antidiuretic, vasopressor and in vitro oxytocic activities.
TP2082 d[Cha4]-AVP

Potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligible vasopressor activity in vivo.
TP2220 Angiotensin 1/2 (1-8) amide

Others Others
Angiotensin 1/2 (1-8) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide) is a peptide analog to angiotensin II that is used as a vasopressor agent in the treatment of certain types of shock and circulatory collapse. It is a potent vasoconstrictor and is us
T36771 11-deoxy Prostaglandin F1α

11-deoxy Prostaglandin F1α

11-deoxy PGF1α is a synthetic analog of PGF1α. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%. 11-deoxy PGF1α is also known to cause rat uterine contractions at a dose 0.3 times that of PGF1α. It also exhibits vasopressor and bronchoconstrictor activities at about half the potency of PGF2α in guinea pigs.
T75826 D[LEU4,LYS8]-VP TFA

D[LEU4,LYS8]-VP TFA 是血管加压素 V1b 受体的选择性激动剂,对大鼠,人类和小鼠 V1b 受体的 Ki 值分别为 0.16 nM,0.52 nM 和 1.38 nM。D[LEU4,LYS8]-VP TFA 具有较弱的抗利尿剂、升压药和体外催产素活性。
T75339 Methylene blue hydrate

亚甲蓝(Basic Blue 9)水合物,作为鸟苷酸环化酶(sGC)、单胺氧化酶A(MAO-A)及NO合酶(NOS)的抑制剂,常用于医疗作为血管加压剂及染料。该化合物通过影响一氧化氮合成酶/鸟苷酸环化酶信号通路,能够减少脉冲前抑制,同时作为一种氧化还原循环化合物,具有穿透血脑屏障的能力,并作为Tau蛋白聚集的抑制剂,有助于缓解脑水肿、减轻小胶质细胞活化和神经炎症。

化合物

Metaraminol tartrate
Cat.No: T0279
Synonym: 重酒石酸间羟胺,Metaradrine tartrate,Metaraminol bitartrate
Target: Adrenergic Receptor
Methylene Blue
Cat.No: T6888
Synonym: 亚甲蓝,methylthioninium chloride,CI-52015,Tetramethylthionine chloride,亚甲兰,Basic Blue 9
Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase
Methylene Blue trihydrate
Cat.No: T0006
Synonym: 碱性亚甲蓝三水合物,Methylthionine chloride,Basic blue 9,亚甲蓝三水合物,Methylene Blue
Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase
d[Leu4,Lys8]-VP acetate
Cat.No: TP1927L1
Synonym: d[Leu4,Lys8]-VP acetate(42061-33-6 free base)
Target: Vasopressin Receptor
d[Cha4]-AVP acetate(500170-27-4 free base)
Cat.No: TP2082L
Synonym:
Target: Vasopressin Receptor
Midodrine D6 hydrochloride
Cat.No: T12035
Synonym: 盐酸米多君 D6
Target: Others
Angiotensin 1/2 (1-7) amide
Cat.No: T22572
Synonym:
Target: Others
Midodrine (R-isomer HCl)
Cat.No: T33384
Synonym: ProAmatine,Midodrine,ST-1085,Gutron,Amatine
Target:
d[Leu4,Lys8]-VP
Cat.No: TP1927
Synonym:
Target:
d[Cha4]-AVP
Cat.No: TP2082
Synonym:
Target:
Angiotensin 1/2 (1-8) amide
Cat.No: TP2220
Synonym:
Target: Others
11-deoxy Prostaglandin F1α
Cat.No: T36771
Synonym: 11-deoxy Prostaglandin F1α
Target:
D[LEU4,LYS8]-VP TFA
Cat.No: T75826
Synonym:
Target:
Methylene blue hydrate
Cat.No: T75339
Synonym:
Target:
TargetMol Loading
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