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Search Results for " uida "

Targets Recommended: P-gp

14

抑制剂 & 化合物

1

天然产物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T11071	Dofequidar fumarate MS-209	P-gp	Membrane transporter/Ion channel; Neuroscience
	Dofequidar fumarate (MS-209) 是口服活性的喹啉化合物，通过抑制 ABCB1/P-gp 和 ABCC1/MDR 相关蛋白 1 来克服 MDR。
T6018	Zosuquidar trihydrochloride 唑喹达三盐酸盐,Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride	P-gp	Membrane transporter/Ion channel; Neuroscience
	Zosuquidar trihydrochloride (LY-335979 trihydrochloride) 是一种P-糖蛋白抑制剂，Ki 值为 59 nM。
T64133L	Laniquidar TFA Laniquidar TFA(197509-46-9 Free base),R101933	P-gp	Membrane transporter/Ion channel; Neuroscience
	Laniquidar TFA (R101933) 是一种新型口服非竞争性P-糖蛋白(P-gp)抑制剂，IC50 值为 0.51 μM。Laniquidar的生物利用度有限，可用于调节多药耐药性转运体。Laniquidar可用于研究急性髓性白血病(AML)和骨髓增生异常综合征(MDS)。
T8426	Encequidar HM30181,HM30181A	P-gp	Membrane transporter/Ion channel; Neuroscience
	Encequidar (HM30181A) 是一种选择性 P-糖蛋白抑制剂。
T11578L	Encequidar mesylate HM30181 mesylate,HM30181A mesylate	P-gp	Membrane transporter/Ion channel; Neuroscience
	Encequidar mesylate (HM30181A mesylate) 是竞争性有效的 P-糖蛋白抑制剂。
T6287	Tariquidar XR9576,他立喹达	P-gp	Membrane transporter/Ion channel; Neuroscience
	Tariquidar (XR9576) 是一种特异性有效的P-糖蛋白抑制剂，Kd 为 5.1 nM。
T68568	Encequidar, HCl
	Encequidar, also known as HM-30181, is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. Encequidar showed the highest potency (IC(50)=0.63nM) among several MDR1 inhibitors, including cycloporin A, XR9576, and GF120918, and effectively blocked transepithelial transport of paclitaxel in MDCK monolayers (IC(50)=35.4nM). Encequidar is currently under clinical trials.
T35064	Viquidacin NXL101,NXL-101,NXL 101
	Viquidacin ( NXL-101) is an oral/intravenous antibiotic that targets Gram-positive bacteria such as MRSA. In 2008, Novexel announced it had discontinued the development of Viquidacin (NXL 101).
T6018L	Zosuquidar
	Zosuquidar (LY335979) 是 P-糖蛋白 (P-glycoprotein) 抑制剂，Ki 值为 59 nM。Zosuquidar 具有抗肿瘤活性，可用于急性髓性白血病 (AML) 研究。
T64133	Laniquidar
	Laniquidar (R101933) 是第三代 P-glycoprotein (P-gp) 的非竞争性抑制剂 (IC50: 0.51 μM)，口服生物利用度有限。Laniquidar 能够用于急性髓细胞白血病 (AML) 和骨髓增生异常综合征 (MDS) 的研究，也能够用于调控多药耐药转运体。
T6287L	Tariquidar dimesylate D 06008,XR9576,D06008,XR 9576,Tariquidar dimesilate,XR-9576
	Tariquidar is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs.
TQ0043	Dofequidar MS-209	P-gp	Membrane transporter/Ion channel; Neuroscience
	Dofequidar (MS-209) is a quinoline compound that can reverse P-glycoprotein (P-gp)-mediated MDR.
T13087	Tariquidar methanesulfonate, hydrate XR9576 methanesulfonate, hydrate	Others	Others
	Tariquidar methanesulfonate, hydrate is a potent and specific P-glycoprotein (P-gp) inhibitor(Kd of 5.1 nM).
T72186	Tariquidar dihydrochloride XR9576 dihydrochloride
	Tariquidar dihydrochloride (XR9576 dihydrochloride) 是一种有效的特异性 P-glycoprotein(P-gp) 抑制剂，Kd 为 5.1 nM。

化合物

Dofequidar fumarate

Cat.No: T11071

Synonym: MS-209

Target: P-gp

Zosuquidar trihydrochloride

Cat.No: T6018

Synonym: 唑喹达三盐酸盐,Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride

Target: P-gp

Cat.No: T64133L

Synonym: Laniquidar TFA(197509-46-9 Free base),R101933

Target: P-gp

Cat.No: T8426

Synonym: HM30181,HM30181A

Target: P-gp

Encequidar mesylate

Cat.No: T11578L

Synonym: HM30181 mesylate,HM30181A mesylate

Target: P-gp

Cat.No: T6287

Synonym: XR9576,他立喹达

Target: P-gp

Encequidar, HCl

Cat.No: T68568

Cat.No: T35064

Synonym: NXL101,NXL-101,NXL 101

Cat.No: T6018L

Cat.No: T64133

Tariquidar dimesylate

Cat.No: T6287L

Synonym: D 06008,XR9576,D06008,XR 9576,Tariquidar dimesilate,XR-9576

Cat.No: TQ0043

Synonym: MS-209

Target: P-gp

Tariquidar methanesulfonate, hydrate

Cat.No: T13087

Synonym: XR9576 methanesulfonate, hydrate

Target: Others

Tariquidar dihydrochloride

Cat.No: T72186

Synonym: XR9576 dihydrochloride

Cat. No.	Product Name	Target	Signaling Pathways
T2S0605	Liquidambaric lactone	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Liquidambaric lactone 是一种分离自Euonymus grandiflorusWall 中的化合物。

天然产物

Liquidambaric lactone

Cat.No: T2S0605

Target: HIV Protease

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00787	GUSB Protein, E. coli, Recombinant (His) uidA,β-glucuronidase,Beta-glucuronidase,GUS	E. coli	E. coli
	Beta-D-glucuronidase from E.coli is a highly specific enzyme in hydrolyzing glucuronides. Beta-D-glucuronidase (GLUase) activity can be measured as the rate of production of fluorescent methylumbelliferone (MU), resulting from the hydrolysis of the substrate 4-methylumbelliferyl-β-d-glucuronide (MUGLU), which is an effective and rapid method for detection and verification of E. coli in food, water, and environmental samples. High purity recombinant beta-Glucuronidase is used in research, bioche...

重组蛋白

GUSB Protein, E. coli, Recombinant (His)

Cat.No: TMPJ-00787

Species: E. coli

Expression System: E. coli

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