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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T2455	PFK-015 PFK15,PFK 015	Glucokinase; Autophagy	Autophagy; Metabolism
	PFK-015 (PFK15) 是一种有效的 PFKFB3 抑制剂，对重组PFKFB3的IC50为110 nM。它能抑制 Y 细胞中的 PFKFB3 活性，IC50为20 nM。
T1575	Nizatidine Axid,Acinon,尼扎替丁,Zanizal	AChE; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Nizatidine (Acinon) 是一种竞争性和可逆的组胺 H2 受体拮抗剂，具有抗酸活性，可用于胃溃疡的研究。
T72107	Werner syndrome RecQ helicase-IN-1	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Werner syndrome RecQ helicase-IN-1 是一种有效的 Werne r 综合征 RecQ DNA 解旋酶 (WRN) 抑制剂，可用研究像结肠癌和胃癌等癌症。
T18310	AZ1508 MC-Lys-MMETA	Others	Others
	AZ1508, a tubulin inhibitor[1], serves as a drug-linker conjugate for antibody-drug conjugates (ADC) targeting breast and stomach cancer treatment.
T71055	Albendazole-d7
	Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helminths, including liver flukes, tapeworms, and roundworms. It eliminates Trichostrongylus in the fourth stomach of cattle and sheep when orally administered at doses ranging from 2.5 to 10 mg/kg as well as other species in the fourth stomach and the small and large intestine. Alben...
T37594	Pericosine A
	Pericosine A is a fungal metabolite that has been found inP. byssoidesand has anticancer activity.1It inhibits the growth of a variety of cancer cells, including breast, colon, lung, ovary, stomach, and prostate cell lines (GI50s = 0.05-24.55 μM) and increases survival in a P388 mouse xenograft model when administered at a dose of 25 mg/kg. Pericosine A inhibits EGFR by 40 to 70% when used at a concentration of 100 μg/ml. It also reacts with organosulfur compounds in skunk spray to form stable t...

化合物

PFK-015

Cat.No: T2455

Synonym: PFK15,PFK 015

Target: Glucokinase, Autophagy

Nizatidine

Cat.No: T1575

Synonym: Axid,Acinon,尼扎替丁,Zanizal

Target: AChE, Histamine Receptor

Werner syndrome RecQ helicase-IN-1

Cat.No: T72107

Synonym:

Target: DNA/RNA Synthesis

AZ1508

Cat.No: T18310

Synonym: MC-Lys-MMETA

Cat. No.	Product Name	Target	Signaling Pathways
T5S0384	Rhapontin Ponticin,土大黄苷,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside	Apoptosis; Others	Apoptosis; Others
	Rhapontin (Ponticin) 是药用大黄的一种成分，可减轻KK/Ay 糖尿病小鼠肝脏脂肪变性，改善血糖和血脂，表明其具有显着的降糖作用，有望成为治疗2型糖尿病及其并发症的新药。
TN5952	2,3-Dihydro-3α-methoxynimbolide
	2,3-Dihydro-3α-methoxynimbolide induces apoptosis via both mitochondrial and death receptor pathways in stomach (AZ521) cancer cell line.