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Search Results for " semi-synthetic antibiotic "

37

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0234	Methicillin sodium salt Methicillin sodium,Meticillin sodium,甲氧西林钠	Antibacterial; Antibiotic	Microbiology/Virology
	Methicillin sodium salt 是β-内酰胺抗生素，抑制参与肽聚糖合成的青霉素结合蛋白。
T67977	Cefazaflur	Antibiotic	Microbiology/Virology
	Cefazaflur 是一种新型半合成头孢菌素衍生物，可被当一种抗菌剂。
T5024	Cefotiam Hexetil Hydrochloride 盐酸头孢替安酯,头孢替安海替酯盐酸盐	Antibacterial; Antibiotic	Microbiology/Virology
	Cefotiam hexetil hydrochloride 是一种可口服头孢菌素，是抗生素 cefotiam 的前药，但无抗菌作用。
T1405	Cefditoren pivoxil 头孢妥仑匹酯,ME 1207,Cefditoren pivaloyloxymethyl ester,Cefditoren pivoxyl	Antibacterial; Antibiotic	Microbiology/Virology
	Cefditoren pivoxil (ME 1207) 是一种半合成、广谱、β-内酰胺酶耐药的第三代头孢菌素抗生素，具有杀菌活性。
T20022	Cephalexin monohydrate Cephalexin hydrate,Cephacillin hydrate,Cefalexin hydrate	Antibiotic	Microbiology/Virology
	Cephalexin monohydrate (Cephalexin hydrate) 是一种可口服的半合成头孢菌素类抗生素，具有显著的抗菌活性，通过靶向青霉素结合蛋白 (PBPs)抑制细菌增殖。
T1143	Carbenicillin disodium BRL-2064,羧苄青霉素钠,Sodium carbenicillin	Cell wall; Antibacterial; Antibiotic	Immunology/Inflammation; Microbiology/Virology
	Carbenicillin disodium (BRL-2064) 作用于细菌细胞壁合成的最后阶段，是β-内酰胺青霉素衍生物。
T2211	Dihydrostreptomycin sulfate Dihydrostreptomycin sesquisulfate,双氢链霉索	Antibacterial; Antibiotic	Microbiology/Virology
	Dihydrostreptomycin sulfate (Dihydrostreptomycin sesquisulfate) 是一种氨基糖苷类抗生素，可研究牛、猪和羊的细菌性疾病。
T0868	Cefepime Dihydrochloride Monohydrate Cefepime HCl,头孢吡肟二盐酸盐一水合物	Antibacterial; Antibiotic; Antifection	Microbiology/Virology
	Cefepime Dihydrochloride Monohydrate (Cefepime HCl) 是一种广谱头孢菌素，对革兰氏阳性菌和革兰氏阴性菌有更高的覆盖率。
T1142	Clindamycin phosphate Clindamycin 2-phosphate,Clindamycin 2-dihydrogen phosphate,NSC 618653,U-28508,克林霉素磷酸酯	ribosome; Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Clindamycin phosphate (Clindamycin 2-dihydrogen phosphate) 是一种抗生素，抑制微生物的核糖体作用。可研究厌氧菌感染和原虫疾病。
T6448	Clindamycin hydrochloride 盐酸克林霉素,Sobelin HCl,Cleocin,Clindamycin HCl,Clinimycin HCl	Antibacterial; Antibiotic	Microbiology/Virology
	Clindamycin hydrochloride (Clinimycin HCl) 是一种半合成的林可胺类抗生素，作用于50S ribosomal 抑制蛋白质合成。
T0133	Cefdinir FK-482,头孢地尼,CI-983,PD 134393	Glutathione Peroxidase; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology
	Cefdinir (FK-482) 是头孢菌素类中的一种半合成广谱抗生素，对几种革兰氏阴性和革兰氏阳性细菌引起的感染有效。它可研究耳，鼻窦，喉咙和皮肤的常见细菌感染。
T1154	Rifaximin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifaximin 是一种胃肠道选择性抗生素，与细菌 DNA 依赖性 RNA 聚合酶的 β 亚基结合，抑制细菌 RNA 合成。与革兰氏阴性菌（MIC：8-50 毫克/毫升）相比，它对革兰氏阳性菌株（MIC：0.03-5 毫克/毫升）的敏感性更高。
T1616	Cefotiam hydrochloride 盐酸头孢替安,Pansporin,SCE-963 hydrochloride,Pansporine,头孢替安盐酸盐,Cefotiam dihydrochloride,Halospor	Antibacterial; Antibiotic	Microbiology/Virology
	Cefotiam hydrochloride (SCE-963 hydrochloride) 是一种肠外头孢菌素类广谱抗生素，对革兰氏阳性菌和革兰氏阴性菌有活性。
T6382	Amikacin disulfate 硫酸阿米卡星,Pierami,阿米卡星硫酸盐,BAY-416651 sulfate,BB-K8,Amikacin sulfate	Antibacterial; Antibiotic	Microbiology/Virology
	Amikacin disulfate (BAY-416651 sulfate) 是氨基糖苷类抗生素，也是卡那霉素的半合成类似物。它具有杀菌作用，直接作用于 30S 和 50S 细菌核糖体亚基，可抑制蛋白质合成。它对大多数革兰氏阴性细菌都有效。它还抑制易感诺卡氏菌和非结核分枝杆菌引起的感染。
T1631	Sulbactam CP45899,舒巴坦,舒巴坦酸	Antibacterial; Antibiotic	Microbiology/Virology
	Sulbactam (CP45899) 是一种竞争性、不可逆的 β-内酰胺酶抑制剂，抑制耐多药不动杆菌-鲍曼不动杆菌复合物。它具有抗菌活性。
T1224	Cefuroxime sodium Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin	Antibacterial; Antibiotic	Microbiology/Virology
	Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素，增加了对 β-内酰胺酶的稳定性。
T1063	Ticarcillin disodium Ticarpen,Ticarcillin disodium salt,替卡西林二钠	Antibacterial; Antibiotic	Microbiology/Virology
	Ticarcillin disodium (Ticarpen) 主要用于抗革兰氏阴性菌, 特别是绿脓杆菌, 也是少数可研究嗜麦芽感染的抗生素。
T26148	RU 25434 RU-25434,RU25434
	RU 25434 is a semi-synthetic aminoglycoside antibiotic.
T25965	Pirlimycin HCl U 57930E,Pirsue,U-57930E,U57930E,Pirlimycin hydrochloride
	Pirlimycin Hydrochloride, a Clindamycin analog, is a semi-synthetic lincosaminide antibiotic.
T25603	Laidlomycin phenylcarbamate
	Laidlomycin phenylcarbamate is a semi-synthetic polyether antibiotic.
T1070L	Cefmetazole Sodium, Cefmetazole,Cefmetazolum,Cefmetazolo
	Cefmetazole is a second-generation semi-synthetic β-lactam cephalosporin antibiotic with antimicrobial activity.
T24590	Paldimycin B Antibiotic 273 A1-beta
	Paldimycin B is a semi-synthetic antibiotic.
T24589	Paldimycin A Antibiotic 273 A1-alpha
	Paldimycin A is a semi-synthetic antibiotic from Streptomyces paulus.
T25424	Flopristin RPR-132552,RPR-132552A,RPR 132552,RPR 132552A
	Flopristin, a semi-synthetic antibiotic of the streptogramin A class, is a fluorinated derivative of pristinamycin IIB.
T26083	Rifametane Rifametanum
	Rifametane is a new semi-synthetic rifamycin, an antibiotic produced naturally by the bacterium Amycolatopsis rifamycinica.
T3052L	Sancycline HCl 6-Demethyl-6-deoxytetracycline,GS-2147,GS2147,GS 2147,NSC 51812 (as hydrochloride),Bonomycin
	Sancycline is a semi-synthetic tetracycline antibiotic that is more active than tetracycline against 339 strains of anaerobic bacteria (MIC90s = 1 and 32 μg/ml, respectively).
T21163	Cloxacillin Sodium BRL-1621 sodium salt,Ankerbin,Cloxapen,Austrastaph,BRL 1621 sodium salt
	Cloxacillin Sodium, a chlorinated derivative of Oxacillin, is a semi-synthetic antibiotic. Cloxacillin is used for the treatment of infections caused by species of staphylococci which produce beta-lactamase.
T69070	Cephradine sodium
	Cephradine sodium is the salt form of Cephradine (free base), a semi-synthetic cephalosporin antibiotic. Cefradin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Cefradin may interfere with autolysin inhibitors.
T68948	Detorubicin HCl
	Detorubicin is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin.
T74669	Gentamicin C1a
	Gentamicin C1a，作为半合成抗生素Etimicin的前体，显示出抗菌活性，并且是Gentamicin复合物中的主要成分。
T70621	Cefditoren Pivoxil HCl
	Cefditoren Pivoxil is a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefditoren pivoxil is a prodrug that is rapidly hydrolyzed by intestinal esterases during absorption to the microbiologically active cefditoren, an active aminothiazolyl cephalosporin. Cefditoren inactivates penicillin binding proteins (PBPs) thereby interfering with peptidoglycan synthesis and inhibiting bacterial cell wall synthesis.
T68909	Detorubicin Free Base
	Detorubicin Free Base is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin.
T69454	Cephradine dihydrate
	Cephradine dihydrate is the hydrate form of Cephradine (free base), a semi-synthetic cephalosporin antibiotic. Cefradin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Cefradin may interfere with autolysin inhibitors.
T75324	Azidocillin
	Azidocillin 是一种半合成青霉素，是一种具有口服活性的 β-内酰胺类抗生素 (antibiotic)。Azidocillin 具有叠氮化功能，并在细菌内 (bacteria) 保持靶向活性。Azidocillin 可用于研究牙科手术引起的骨炎，或中耳炎、肠球菌败血症和其他细菌感染性疾病。
T69873	Cefdinir monohydrate
	Cefdinir monohydrate is the salt form of Cefdinir (free base), a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidog...
TMIH-0530	Sulbactam-d2
	Sulbactam-d2 是 Sulbactam 的氘代化合物。Sulbactam 的 CAS 号为 68373-14-8。Sulbactam是一种竞争性、不可逆的 β-内酰胺酶抑制剂，抑制耐多药不动杆菌-鲍曼不动杆菌复合物。它具有抗菌活性。
T80731	Zifanocycline TFA KBP-7072 TFA
	Zifanocycline TFA (KBP-7072) 是一种半合成的氨基糖苷类抗生素，具有口服活性并能抑制细菌核糖体功能。它对广泛的革兰氏阳性菌和阴性菌示出了体外抗菌活性，包括多种耐药病原体。Zifanocycline TFA 适用于急性细菌性皮肤及皮肤结构感染、社区获得性细菌性肺炎和复杂的腹腔感染的研究。

化合物

Methicillin sodium salt

Cat.No: T0234

Synonym: Methicillin sodium,Meticillin sodium,甲氧西林钠

Target: Antibacterial, Antibiotic

Cat.No: T67977

Target: Antibiotic

Cefotiam Hexetil Hydrochloride

Cat.No: T5024

Synonym: 盐酸头孢替安酯,头孢替安海替酯盐酸盐

Target: Antibacterial, Antibiotic

Cefditoren pivoxil

Cat.No: T1405

Synonym: 头孢妥仑匹酯,ME 1207,Cefditoren pivaloyloxymethyl ester,Cefditoren pivoxyl

Target: Antibacterial, Antibiotic

Cephalexin monohydrate

Cat.No: T20022

Synonym: Cephalexin hydrate,Cephacillin hydrate,Cefalexin hydrate

Target: Antibiotic

Carbenicillin disodium

Cat.No: T1143

Synonym: BRL-2064,羧苄青霉素钠,Sodium carbenicillin

Target: Cell wall, Antibacterial, Antibiotic

Dihydrostreptomycin sulfate

Cat.No: T2211

Synonym: Dihydrostreptomycin sesquisulfate,双氢链霉索

Target: Antibacterial, Antibiotic

Cefepime Dihydrochloride Monohydrate

Cat.No: T0868

Synonym: Cefepime HCl,头孢吡肟二盐酸盐一水合物

Target: Antibacterial, Antibiotic, Antifection

Clindamycin phosphate

Cat.No: T1142

Synonym: Clindamycin 2-phosphate,Clindamycin 2-dihydrogen phosphate,NSC 618653,U-28508,克林霉素磷酸酯

Target: ribosome, Antibacterial, Antibiotic, Parasite

Clindamycin hydrochloride

Cat.No: T6448

Synonym: 盐酸克林霉素,Sobelin HCl,Cleocin,Clindamycin HCl,Clinimycin HCl

Target: Antibacterial, Antibiotic

Cat.No: T0133

Synonym: FK-482,头孢地尼,CI-983,PD 134393

Target: Glutathione Peroxidase, Antibacterial, Antibiotic

Cat.No: T1154

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cefotiam hydrochloride

Cat.No: T1616

Synonym: 盐酸头孢替安,Pansporin,SCE-963 hydrochloride,Pansporine,头孢替安盐酸盐,Cefotiam dihydrochloride,Halospor

Target: Antibacterial, Antibiotic

Amikacin disulfate

Cat.No: T6382

Synonym: 硫酸阿米卡星,Pierami,阿米卡星硫酸盐,BAY-416651 sulfate,BB-K8,Amikacin sulfate

Target: Antibacterial, Antibiotic

Cat.No: T1631

Synonym: CP45899,舒巴坦,舒巴坦酸

Target: Antibacterial, Antibiotic

Cefuroxime sodium

Cat.No: T1224

Synonym: Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin

Target: Antibacterial, Antibiotic

Ticarcillin disodium

Cat.No: T1063

Synonym: Ticarpen,Ticarcillin disodium salt,替卡西林二钠

Target: Antibacterial, Antibiotic

Cat.No: T26148

Synonym: RU-25434,RU25434

Cat.No: T25965

Synonym: U 57930E,Pirsue,U-57930E,U57930E,Pirlimycin hydrochloride

Laidlomycin phenylcarbamate

Cat.No: T25603

Cat.No: T1070L

Synonym: Sodium, Cefmetazole,Cefmetazolum,Cefmetazolo

Cat.No: T24590

Synonym: Antibiotic 273 A1-beta

Cat.No: T24589

Synonym: Antibiotic 273 A1-alpha

Cat.No: T25424

Synonym: RPR-132552,RPR-132552A,RPR 132552,RPR 132552A

Cat.No: T26083

Synonym: Rifametanum

Cat.No: T3052L

Synonym: 6-Demethyl-6-deoxytetracycline,GS-2147,GS2147,GS 2147,NSC 51812 (as hydrochloride),Bonomycin

Cloxacillin Sodium

Cat.No: T21163

Synonym: BRL-1621 sodium salt,Ankerbin,Cloxapen,Austrastaph,BRL 1621 sodium salt

Cephradine sodium

Cat.No: T69070

Detorubicin HCl

Cat.No: T68948

Cat.No: T74669

Cefditoren Pivoxil HCl

Cat.No: T70621

Detorubicin Free Base

Cat.No: T68909

Cephradine dihydrate

Cat.No: T69454

Cat.No: T75324

Cefdinir monohydrate

Cat.No: T69873

Cat.No: TMIH-0530

Zifanocycline TFA

Cat.No: T80731

Synonym: KBP-7072 TFA

Cat. No.	Product Name	Target	Signaling Pathways
T1151	Roxithromycin Roxl-150,罗红霉素,RU-28965	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Roxithromycin (RU-28965) 是半合成的大环内酯类抗生素。
TQ0152	Dalfopristin RP54476,达福普汀	Antibacterial; Antibiotic	Microbiology/Virology
	Dalfopristin (RP54476) 是一种半合成的链霉素抗生素。 Quinupristin/Dalfopristin (Q/D) 用于治疗耐多药粪肠球菌感染。
T1419	Azithromycin hydrate CP-62993 dihydrate,阿奇霉素二水物,Azithromycin dihydrate,阿奇霉素二水合物	ribosome; Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Azithromycin hydrate (CP-62993 dihydrate) 是一种大环内酯抗生素，可研究细菌感染。

天然产物

Cat.No: T1151

Synonym: Roxl-150,罗红霉素,RU-28965

Target: ribosome, Antibacterial, Antibiotic

Cat.No: TQ0152

Synonym: RP54476,达福普汀

Target: Antibacterial, Antibiotic

Azithromycin hydrate

Cat.No: T1419

Synonym: CP-62993 dihydrate,阿奇霉素二水物,Azithromycin dihydrate,阿奇霉素二水合物

Target: ribosome, Antibacterial, Antibiotic, Autophagy

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