首页工具

登录

搜索结果

Search Results for " plasmin "

35

抑制剂 & 化合物

1

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T78018	Plasminogen
	Plasminogen是一种可由尿激酶血浆蛋白原激活剂(uPA)或组织血浆蛋白原激活剂(tPA)裂解激活的分泌性蛋白，生成血浆蛋白，该酶可以广泛裂解纤维蛋白及其他ECM成分。作为促炎调节剂，Plasminogen能促进急性及糖尿病相关伤口愈合。该蛋白在伤口愈合、炎症和低纤溶酶原血症的研究中有重要应用。
T13408	ZK824190	Others; Serine Protease	Others; Proteases/Proteasome
	ZK824190 是具有口服活性尿激酶型纤溶酶原激活剂 (uPA) 选择性抑制剂，对 uPA，tPA 和 Plasmin 的IC50分别为 237，1600 和 1850 nM。ZK824190在多发性硬化症中有研究价值。
T8362	Benzamidine hydrochloride Benzamidine HCl,苄脒盐酸盐	Serine/threonin kinase; Serine Protease	Cell Cycle/Checkpoint; Metabolism; Proteases/Proteasome
	Benzamidine hydrochloride (Benzamidine HCl) 是可逆的胰蛋白酶样丝氨酸蛋白酶 (trypsin-like serine proteases) 竞争性抑制剂，对 uPA、类胰蛋白酶、胰蛋白酶和 Xa 因子作用的Ki 分别为 97 µM、20 µM、21 µM 和 110 µM。
T6370	AEBSF hydrochloride AEBSF HCl,Pefabloc SC	Thrombin; Serine Protease; Influenza Virus	Microbiology/Virology; Proteases/Proteasome
	AEBSF hydrochloride (Pefabloc SC) 是一种丝氨酸蛋白酶的不可逆抑制剂。
TP1792L	KKI-5 acetate(97145-43-2 free base)	Serine Protease	Proteases/Proteasome
	KKI-5 acetate(97145-43-2 free base) 是一种丝氨酸蛋白酶抑制剂，可抑制激肽释放酶和纤溶酶。 KKI 5 可能表现出抗癌化疗益处，也可用作血管性水肿的治疗方法。
T0372	Gabexate mesylate 甲磺酸加贝酯,FOY	Factor Xa; Serine Protease; Proteasome	Metabolism; Proteases/Proteasome; Ubiquitination
	Gabexate mesylate (FOY) 是一种非抗原的类胰蛋白酶丝氨酸蛋白酶抑制剂。
T13409	ZK824859	Others	Others
	ZK824859 is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).
T13409L	ZK824859 hydrochloride (2271122-53-1 free base) ZK824859 hydrochloride	Others	Others
	ZK824859 hydrochloride is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).
T9670L	Patamostat HCl Patamostat HCl（114568-26-2 Free base）	Serine Protease; Protease	Proteases/Proteasome
	Patamostat HCl 是一种具有高效性和选择性的小分子蛋白酶 (protease) 抑制剂，对胰蛋白酶，纤溶酶和凝血酶有抑制作用，IC50 值分别为 39 nM，950 nM 和 1.9 μM。Patamostat HCl 可用于研究急性胰腺炎。
T25811	Micropeptin 478B
	Micropeptin 478B is a plasmin inhibitor from the Cyanobacterium Microcystis aeruginosa.
T25810	Micropeptin 478A Micropeptin 478 A,Micropeptin 478-A
	Micropeptin 478A is a plasmin inhibitor from the Cyanobacterium Microcystis aeruginosa.
T38521	Patamostat mesylate E-3123 mesylate
	Patamostat mesylate (E-3123) is a highly potent protease inhibitor, displaying strong inhibitory activity against trypsin, plasmin, and thrombin, with IC 50 values of 39 nM, 950 nM, and 1.9 μM, respectively. This compound, Patamostat mesylate, shows promising potential in suppressing the pathogenesis and development of acute pancreatitis.
T38736	Nattokinase
	Nattokinase is a powerful fibrinolytic enzyme that effectively hydrolyzes fibrin and plasmin substrate, leading to the breakdown of blood clots. Its efficacy renders it valuable for cardiovascular disease studies.
T69500	YO-2
	YO-2 is a selective plasmin inhibitor. YO-2 induces thymocyte apoptosis via activation of caspase cascade.
T72736	Aeruginosin 98-B
	Aeruginosin 98-B为一种蛋白酶抑制剂，能够抑制胰蛋白酶、纤溶酶和凝血酶，其IC50值依次为0.6、7.0和10.0 μg/mL。
TP1013	N-CBZ-Phe-Arg-AMC Z-FR-AMC
	N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a substrate for serine proteases, including cathepsins, kallikrein and plasmin. Absorption/emission of substrate = 330/390 nm (weak fluorescence); absorption/emission of end product (AMC) = 342/441 nm (strong fluorescence).
T22451	UK-371804 HCl	Serine Protease	Proteases/Proteasome
	UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-fold versus plasmin and 4000-fold versus tPA).
T36225	N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)
	N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin.1,2,3Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to releasep-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasmin activity. 1.Jespersen, J., Gram, J., and Astrup, T.The autodigestion of human plasmin follows a bimolecular mode of reaction subject to product inhibitionThromb. Res.41(3)395-404(1986) 2.Kim, S.H., and Choi, N.S.Electrophoretic analysis of protease inhibitor...
T40614	LCKLSL
	LCKLSL, an N-terminal hexapeptide, acts as a competitive inhibitor of annexin A2 (AnxA2), effectively preventing the binding of tissue plasminogen activator (tPA) to AnxA2 while also inhibiting the generation of plasmin. In addition, LCKLSL exhibits anti-angiogenic properties.
T62731	ZK824190 hydrochloride
	ZK824190 hydrochloride 是一种选择性的、口服具有活力的尿激酶型纤溶酶原激活剂 (uPA) 抑制剂，能够作用于 uPA (IC50: 237 nM)、tPA (IC50: 1600 nM) 和 Plasmin (IC50: 1850 nM)。ZK824190 hydrochloride 能够用于研究多发性硬化症的研究
T37019	p-APMSF (hydrochloride)
	p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these proteases over bovine chymotrypsin and acetylcholinesterase.
T72113	6-Aminocaproic acid hydrochloride EACA hydrochloride,EACA hydrochloride ; Epsilon-Amino-n-caproic Acid hydrochloride ; 6-Aminohexanoic acid hydrochloride,6-Aminohexanoic acid hydrochloride,Epsilon-Amino-n-caproic Acid hydrochloride
	6-Aminocaproic acid hydrochloride，一种单氨基羧酸，作为有效及口服活性的纤溶酶和纤溶酶原抑制剂，具备显著的抗纤溶能力。通过竞争性结合纤溶酶原上的赖氨酸残基，6-Aminocaproic acid hydrochloride 阻止血块溶解，抑制纤溶酶生成，减少纤维蛋白溶解，用于出血性疾病研究。
TP1792	KKI-5
	KKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.
T6564L	Leupeptin Leupeptin Ac-LL,NK-381
	Leupeptin is a competitive protease inhibitor produced by actinomycetes. Leupeptin can inhibit cysteine, serine and threonine peptidases. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine p
T36962	MMP Inhibitor I (trifluoroacetate salt)
	MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 μM, respectively). It is selective for MMP-1, MMP-2, and MMP-3 over the proteases thermolysin, urease, trypsin, α-chymotrypsin, plasmin, and elastase at concentrations up to 4 mM.
T69294	UK‑396082
	UK-396082为一有效的TAFI抑制剂，能增进纤溶酶活性并促使ECM水平下降，适用于CKD研究。
T3359	Aprotinin 抑酶肽,抑肽酶,Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin	Others; Serine Protease; Influenza Virus; Proteasome	Microbiology/Virology; Others; Proteases/Proteasome; Ubiquitination
	Aprotinin (Traskolan) 是分离自牛肺的一种广谱丝氨酸蛋白酶抑制剂，可抑制多种不同酯酶和蛋白酶的活性。
TP2482	LCKLSL acetate LCKLSL acetate(533902-29-3 free base)	Annexin A	GPCR/G Protein
	LCKLSL acetate 是一种竞争性膜联蛋白 A2 (AnxA2) 抑制剂。 LCKLSL acetate 有效抑制组织纤溶酶原激活剂 (tPA) 与 AnxA2 的结合和纤溶酶的产生。 LCKLSL acetate 具有抗血管生成作用。
T69297	Leupeptin HCl
	Leupeptin is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine peptidases. Leupeptin is an organic compound produced by actinomycetes. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine proteinases (papain, cathepsin B (Ki = 4.1 nM), endoproteinase Lys-C). It does not inhibit α-chymotrypsin or thrombin. Leupeptin is a competitive transition state inhibitor and its inhibition may be relieved by...
T41085	UK122 UK122
	UK122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (uPA) with an IC50 value of 0.2 μM. It displays negligible to minimal inhibition towards tissue-type plasminogen activator (tPA), plasmin, thrombin, and trypsin (all IC50 >100 μM). Functioning as a 4-oxazolidinone analogue, UK122 is an anticancer agent that effectively inhibits cancer cell migration and invasion.
T35579	PKSI-527
	PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 μM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and λ-carrageenan ex vivo in human plasma. It also prolongs partial thromboplastin and euglobulin clot lysis times. In vivo, PKSI-527 (300 mg/kg per day) reduces hyperplasia, pannus formation, and infiltration of in...
T78015	LCKLSL hydrochloride
	LCKLSL hydrochloride为N端六肽，作为膜联蛋白A2（AnxA2）的竞争性抑制剂，有效阻止组织纤溶酶原激活物（tPA）与AnxA2结合。此化合物还能够抑制纤溶酶生成，并表现出抗血管生成活性。
T27698	JTV-803 mesylate JTV803,JTV 803,JTV-803
	JTV-803 is a factor Xa inhibitor. JTV-803 showed a competitive inhibitory effect on human factor Xa, with a K(i) value of 0.019 microM and IC(50) value of 0.081 microM. JTV-803 was 100 times more selective in inhibiting human factor Xa as compared to its
T73701	Urokinase (peptidolytic)
	Urokinase peptidolytic (Urokinase-type plasminogen activator) 是一种丝氨酸蛋白酶，是丝氨酸蛋白酶纤溶酶的一种非活性形式(酶原)。纤溶酶的激活可触发蛋白水解级联反应，进而参与血栓溶解或细胞外基质降解，涉及血管疾病和癌症相关研究。
T9670	Patamostat
	Patamostat (E-3123)是一种有效的蛋白酶抑制剂，对胰蛋白酶、纤溶酶和凝血酶具有显著抑制效果，其IC50值分别为39 nM、950 nM和1.9 μM。Patamostat可能在急性胰腺炎的发病机制和发展中发挥抑制作用。

化合物

Cat.No: T78018

Cat.No: T13408

Target: Others, Serine Protease

Benzamidine hydrochloride

Cat.No: T8362

Synonym: Benzamidine HCl,苄脒盐酸盐

Target: Serine/threonin kinase, Serine Protease

AEBSF hydrochloride

Cat.No: T6370

Synonym: AEBSF HCl,Pefabloc SC

Target: Thrombin, Serine Protease, Influenza Virus

KKI-5 acetate(97145-43-2 free base)

Cat.No: TP1792L

Target: Serine Protease

Gabexate mesylate

Cat.No: T0372

Synonym: 甲磺酸加贝酯,FOY

Target: Factor Xa, Serine Protease, Proteasome

Cat.No: T13409

Target: Others

ZK824859 hydrochloride (2271122-53-1 free base)

Cat.No: T13409L

Synonym: ZK824859 hydrochloride

Target: Others

Cat.No: T9670L

Synonym: Patamostat HCl（114568-26-2 Free base）

Target: Serine Protease, Protease

Micropeptin 478B

Cat.No: T25811

Micropeptin 478A

Cat.No: T25810

Synonym: Micropeptin 478 A,Micropeptin 478-A

Patamostat mesylate

Cat.No: T38521

Synonym: E-3123 mesylate

Cat.No: T38736

Cat.No: T69500

Aeruginosin 98-B

Cat.No: T72736

N-CBZ-Phe-Arg-AMC

Cat.No: TP1013

Synonym: Z-FR-AMC

Cat.No: T22451

Target: Serine Protease

N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)

Cat.No: T36225

Cat.No: T40614

ZK824190 hydrochloride

Cat.No: T62731

p-APMSF (hydrochloride)

Cat.No: T37019

6-Aminocaproic acid hydrochloride

Cat.No: T72113

Synonym: EACA hydrochloride,EACA hydrochloride ; Epsilon-Amino-n-caproic Acid hydrochloride ; 6-Aminohexanoic acid hydrochloride,6-Aminohexanoic acid hydrochloride,Epsilon-Amino-n-caproic Acid hydrochloride

Cat.No: TP1792

Cat.No: T6564L

Synonym: Leupeptin Ac-LL,NK-381

MMP Inhibitor I (trifluoroacetate salt)

Cat.No: T36962

Cat.No: T69294

Cat.No: T3359

Synonym: 抑酶肽,抑肽酶,Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin

Target: Others, Serine Protease, Influenza Virus, Proteasome

Cat.No: TP2482

Synonym: LCKLSL acetate(533902-29-3 free base)

Target: Annexin A

Cat.No: T69297

Cat.No: T41085

Synonym: UK122

Cat.No: T35579

LCKLSL hydrochloride

Cat.No: T78015

JTV-803 mesylate

Cat.No: T27698

Synonym: JTV803,JTV 803,JTV-803

Urokinase (peptidolytic)

Cat.No: T73701

Cat.No: T9670

Cat. No.	Product Name	Target	Signaling Pathways
T0881	6-Aminocaproic acid 氨基己酸,EACA,6-氨基己酸,6-Aminohexanoic acid,Epsilon-Amino-n-caproic Acid,(6-)ε-Aminocaproic acid	Others	Others
	6-Aminocaproic acid (EACA) 是一种单氨基羧酸，是一种有效的、具有口服活性的纤溶酶和纤溶酶原的抑制剂。它是一种有效的抗纤维蛋白溶解剂，能够竞争性结合纤溶酶原上的赖氨酸残基，防止血块溶解，并抑制纤溶酶的形成，减少纤维蛋白溶解。它可用于出血性疾病的研究。

天然产物

6-Aminocaproic acid

Cat.No: T0881

Synonym: 氨基己酸,EACA,6-氨基己酸,6-Aminohexanoic acid,Epsilon-Amino-n-caproic Acid,(6-)ε-Aminocaproic acid

Target: Others

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼