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Cat. No.	Product Name	Target	Signaling Pathways
T8452	Dantrolene	Others	Others
	Dantrolene 是一种肌肉松弛剂，是人红细胞谷胱甘肽还原酶的非竞争性抑制剂，其Ki 和IC50值分别为 111.6 μM 和 52.3 μM。它是兰尼碱受体拮抗剂及Ca2+信号稳定剂。它可用于研究恶性高热、亨廷顿病、肌肉痉挛和其他神经阻滞剂恶性综合征。
T3086	Mesoridazine Besylate Mesoridazine benzenesulfonate,Serentil,苯磺酸美索达嗪	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Mesoridazine Besylate (Serentil) 是一种哌啶类精神安定药，属于称为吩噻嗪类的药物，用于治疗精神分裂症。它是硫利达嗪的代谢物。
T7943	Fluphenazine decanoate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fluphenazine decanoate 是一种高度连续的多巴胺 D2受体阻滞剂，是一种长效吩噻嗪抗精神病药，用于精神分裂症的研究。
T1478	Ondansetron hydrochloride dihydrate 盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Ondansetron hydrochloride dihydrate (GR 38032) 是5- HT3受体拮抗剂，可治疗化疗后的恶心和呕吐，有抗焦虑和抗精神病作用。
T83648	Tenilapine	Others	Others
	Tenilapine 是一种神经安定化合物，可用于研究非典型抗精神病。
T11121	Duoperone	Others	Others
	Duoperone 是一种抗精神病药。Duoperone 在动物模型中显示出止吐活性。
T7561	Benzetimide hydrochloride 盐酸苄替米特,R4929	AChR	Neuroscience
	Benzetimide hydrochloride (R4929) 是毒蕈碱乙酰胆碱受体的拮抗剂，用于治疗神经安定药引起的帕金森症。
T6398	Azaperone R-1929,Fluoperidol,阿扎哌隆,Stresnil,NSC 170976,Suicalm	Others; Dopamine Receptor	GPCR/G Protein; Neuroscience; Others
	Azaperone (Fluoperidol) 是多巴胺拮抗剂，具有一些抗组胺和抗胆碱特性，具有止吐活性。
T14830	Bromperidol 溴哌利多,R-11333	5-HT Receptor	GPCR/G Protein; Neuroscience
	Bromperidol (R-11333) 是一种苯丁酮衍生物，是一种强效长效精神安定药。它被用作治疗精神分裂症的抗精神病药。
T0025	Haloperidol Aloperidin,氟哌啶醇,Serenace,Haldol	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Haloperidol (Serenace) 是一种安定药，是一种dopamine D2 receptor 拮抗剂。
T67811	Tefludazine
	Tefludazine 一种具有苯茚酮结构的新型神经抑制剂，是一种具有良好口服活性且与多巴胺和5-羟色胺受体有拮抗作用的化合物。Tefludazine 在小鼠、大鼠和狗的体外和体内测试模型中表现出强大的多巴胺（DA）拮抗活性。Tefludazine 是一种用来治疗精神类疾病的潜在化合物。
T0455	Clozapine 氯氮平,HF 1854,LX 100-129	Dopamine Receptor; Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	Clozapine (HF 1854) 是一种三环二苯二氮卓类药物，属于非典型抗精神病药物。它结合几种类型的中枢神经系统受体，并显示出独特的药理学特征。它是一种血清素拮抗剂，与 5-HT 2A/2C 受体亚型具有强结合力。它还对几种多巴胺能受体表现出很强的亲和力，但对多巴胺 D2 受体仅表现出较弱的拮抗作用，这种受体通常被认为可调节精神抑制活性。
T35315	Zoloperone Zoloperonum,LR511,LR 511,LR-511
	Zoloperone is a neuroleptic.
T34169	Prothipendyl
	Prothipendyl is a neuroleptic azaphenothiazine.
T34731	SU 23397 SU-23397,SU23397
	SU 23397 is a structurally unique neuroleptic agent.
T26360L	Benperidol Hydrochloride
	Benperidol Hydrochloride is a potent D2/D4 dopamine receptor antagonist, used as antipsychotic and neuroleptic.
T0445L1	Promethazine hibenzate D-08768,D08768,D 08768
	Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family.
T71926	Melperone hydrochloride
	Melperone hydrochloride is a butyrophenone neuroleptic and an inhibitor of the CYP2D6 catalyzed O-demethylation of venlafaxine.
T15104	Dexetimide (+)-Benzetimide,Dexbenzetimide,(S)-(+)-Dexetimide	Others	Others
	Dexetimide ((+)-Benzetimide) is a high-affinity antagonist of the muscarinic receptor. It is a persistent anticholinergic agent and can be used to treat neuroleptic-induced parkinsonism.
T34061	Picobenzide M 14012-4,MA 14012
	Picobenzide, also known as M-14012-4, is a neuroleptic agent,
T15743	Levomepromazine Methotrimeprazine	Others	Others
	Methotrimeprazine is an orally available neuroleptic agent. It is commonly used to relieve nausea and vomiting in palliative care settings. Levomepromazine has antagonist actions at multiple neurotransmitter receptor sites, including cholinergic, dopamine
T26472	A23887 A-23887,A 23887
	A23887 is a potentially neuroleptic tetracyclic spiro amine that has affinity for dopamine D-2 receptors.
T69825	Dexetimide HCl
	Dexetimide HCl is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.
T70425	Amiperone
	Amiperone is a neuroleptic drug. It prolonged the latency and reduced the frequency of the noise escape response rate in rats. It also inhibited lever-press response and reduced the shock-avoidance rate at very low dose levels in rats.
T15026	Cyamemazine	5-HT Receptor	GPCR/G Protein; Neuroscience
	Cyamemazine, contains the phenothiazine chromophore, is a neuroleptic agent used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki: 12 nM), 5-HT2A (Ki: 1.5 nM) and 5-HT2C (Ki: 75 nM) receptors antagonist with antipsychotic activity.
T78535	trans-Clopenthixol dihydrochloride (E)-Clopenthixol dihydrochloride	Parasite	Microbiology/Virology
	trans-Clopenthixol ((E)-Clopenthixol) diHCl为一种抗生素，具备抗菌性质但不具有镇静效果。该化合物能够用于抑制体外铜绿假单胞菌与恶性疟原虫。
T61006	Tropatepine
	Tropatepine 是具有口服活性的抗胆碱能毒蕈碱拮抗剂。Tropatepine 是一种抗帕金森病的药物，可用于研究由抗精神病药物所引起的锥体外系综合征。
T69129	Clozapine HCl
	Clozapine HCl is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a ...
T60943	Tiapride
	Tiapride 是一种非典型的抗精神病剂，不会引起强直性昏厥和镇静。Tiapride 是多巴胺 D2受体的选择性拮抗剂，其对 D1；D2；D3；D4 受体的 IC50值分别为 1440、45.8、>100 和 11.7 μM。

化合物

Cat.No: T8452

Target: Others

Mesoridazine Besylate

Cat.No: T3086

Synonym: Mesoridazine benzenesulfonate,Serentil,苯磺酸美索达嗪

Target: Dopamine Receptor, 5-HT Receptor

Fluphenazine decanoate

Cat.No: T7943

Target: Dopamine Receptor

Ondansetron hydrochloride dihydrate

Cat.No: T1478

Synonym: 盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride

Target: 5-HT Receptor

Cat.No: T83648

Target: Others

Cat.No: T11121

Target: Others

Benzetimide hydrochloride

Cat.No: T7561

Synonym: 盐酸苄替米特,R4929

Target: AChR

Cat.No: T6398

Synonym: R-1929,Fluoperidol,阿扎哌隆,Stresnil,NSC 170976,Suicalm

Target: Others, Dopamine Receptor

Cat.No: T14830

Synonym: 溴哌利多,R-11333

Target: 5-HT Receptor

Cat.No: T0025

Synonym: Aloperidin,氟哌啶醇,Serenace,Haldol

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T67811

Cat.No: T0455

Synonym: 氯氮平,HF 1854,LX 100-129

Target: Dopamine Receptor, Adrenergic Receptor, AChR

Cat.No: T35315

Synonym: Zoloperonum,LR511,LR 511,LR-511

Cat.No: T34169

Cat.No: T34731

Synonym: SU-23397,SU23397

Benperidol Hydrochloride

Cat.No: T26360L

Promethazine hibenzate

Cat.No: T0445L1

Synonym: D-08768,D08768,D 08768

Melperone hydrochloride

Cat.No: T71926

Cat.No: T15104

Synonym: (+)-Benzetimide,Dexbenzetimide,(S)-(+)-Dexetimide

Target: Others

Cat.No: T34061

Synonym: M 14012-4,MA 14012

Levomepromazine

Cat.No: T15743

Synonym: Methotrimeprazine

Target: Others

Cat.No: T26472

Synonym: A-23887,A 23887

Cat.No: T69825

Cat.No: T70425

Cat.No: T15026

Target: 5-HT Receptor

trans-Clopenthixol dihydrochloride

Cat.No: T78535

Synonym: (E)-Clopenthixol dihydrochloride

Target: Parasite

Cat.No: T61006

Cat.No: T69129

Cat.No: T60943

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