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Cat. No.	Product Name	Target	Signaling Pathways
T39392L	C-Type Natriuretic Peptide (CNP) (1-22), human acetate C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)	Others	Others
	C-Type Natriuretic Peptide (CNP) (1-22), human acetate 是一种利钠肽受体 B (NPR-B) 的激动剂，一种内皮衍生的松弛剂和生长抑制因子。 C-Type Natriuretic Peptide (CNP) (1-22), human acetate 抑制由组胺和 5-HT 或直接由毛喉素刺激的 cAMP 合成。
TP1187	C-Type Natriuretic Peptide (CNP) (1-22), human CNP (1-22), human	RAAS	Endocrinology/Hormones
	C-Type Natriuretic Peptide (CNP) (1-22), human 是一种利钠肽受体 B (NPR-B) 激动剂，是一种 CNP 的 1-22 片段。它对生理激动剂组胺和 5-HT 刺激或直接由 Forskolin 刺激的 cAMP 合成具有抑制作用。其中CNP 是一种有效的、内皮衍生的松弛剂和生长抑制因子。
TP1219	Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate ANP (1-28), human, porcineANP(1-28)
	Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 是颗粒鸟苷酸环化酶的刺激剂，已被发现通过增加环鸟苷单磷酸的合成来保护分离的心肌细胞免受复氧诱导的高收缩。Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 也有助于在反复运动期间刺激脂解，并在运动期间控制脂解。
T39246	Brain Natriuretic Peptide-45, mouse Brain Natriuretic Peptide-45, mouse,BNP-45, mouse
	Mouse Brain Natriuretic Peptide-45 (BNP-45, mouse) is a circulating variant of the mouse brain natriuretic peptide derived from the mouse heart. It exhibits powerful hypotensive and natriuretic properties.
T35832	Brain Natriuretic Peptide (1-32), rat acetate
	Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a 32 amino acid polypeptide hormone synthesized by ventricular cardiomyocytes as a result of myocardial cell stretching (cardiomyocyte distension)[1].
T39392	C-Type Natriuretic Peptide (CNP) (1-22), human TFA
	C-Type Natriuretic Peptide (CNP) (1-22), human (TFA), is a 22 amino acid fragment of CNP and functions as an agonist for the natriuretic peptide receptor B (NPR-B). It can inhibit cAMP synthesis, which is induced by histamine, 5-HT, or Forskolin. Additionally, CNP exhibits strong endothelial-derived relaxation properties and acts as a growth inhibitor.
T83905	Brain Natriuretic Peptide-32 (rat) acetate BNP (14-45),B-type Natriuretic Peptide-32,Brain Natriuretic Polypeptide-32,BNP-32
	BNP-32（Brain natriuretic peptide-32）是心血管激素前体proBNP的肽段，能够结合大鼠血管平滑肌上的利钠肽受体（IC50 = 7.3 nM），并在同样的细胞中促进cGMP积累（EC50 = 170 nM）。BNP-32还能使经去甲肾上腺素预收缩的孤立大鼠主动脉条带松弛（EC50 = 6.7 nM），当以3 µg/kg的剂量给药时，能增加大鼠的尿量和尿液电解质排泄，并诱导低血压。
T39244	Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled
	Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, is one of three mammalian natriuretic peptides (NPs) that exerts endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide holds promise for cardiovascular diseases research.
TP1221	Atrial Natriuretic Peptide (ANP) (1-28), rat Atrial natriuretic factor (1-28) (rat)
	Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.
TP1756	Brain Natriuretic Peptide (1-32), rat Brain Natriuretic Peptide (BNP) (1-32), rat
	Brain Natriuretic Peptide (BNP) (1-32), rat is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).Brain natriuretic peptide (type B natriuretic peptide) was origin
TP1207	Brain Natriuretic Peptide-45, rat BNP-45 (rat),Brain natriuretic peptide-45 rat
	BNP-45 (rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency.
TP1581	C-Type Natriuretic Peptide (1-53), human
	CNP, a member of the natriuretic peptide family, was first identified in porcine brain and later found in other mammals as well as non-mammals. Processing of the CNP precursor gives rise to CNP-22 and its N-terminally elongated form, CNP-53. The CNPs shar
TP1220L	Carperitide acetate 醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate	Endothelin Receptor	GPCR/G Protein
	Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate) 是一种由 28 个氨基酸组成的激素，由心脏产生并分泌，以响应心脏损伤和机械拉伸。Carperitide acetate 抑制内皮素-1 (endothelin-1) 分泌。
T41065	Atrial natriuretic factor (1-28) (human, porcine) Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28)
	Atrial natriuretic factor (1-28) from both human and porcine sources is a powerful suppressor of pro-opiomelanocortin (POMC) mRNA, while it only has a modest inhibition effect on βEP-LI release.
T82586	Dendroaspis Natriuretic Peptide
	Dendroaspis Natriuretic Peptide为源于动物毒液的血管舒张肽类化合物。
TP1208	Nesiritide BNP-32,Brain Natriuretic Peptide-32 human,奈西立肽
	Nesiritide is the recombinant form of the 32 amino acid human B-type natriuretic peptide, which is normally produced by the ventricular myocardium. It is an agonist of natriuretic peptide receptors (NPRs), with Kd values of 7.3 and 13 pM for NPR-A and NPR
TP1218	Atrial natriuretic factor (1-28) (rat) TFA Atrial Natriuretic Peptide (ANP) (1-28), rat TFA
	Atrial Natriuretic Peptide (ANP) (1-28),rat (TFA) is the main circulating forms of Atrial Natriuretic Peptide (ANP) in rats, which strongly inhibit the secretion of Ang II - stimulated endothelin-1.
TP1220	Carperitide Atrial Natriuretic Peptide (ANP) (1-28), human, porcine
	Carperitide, a 28-amino acid hormone known as Atrial Natriuretic Peptide (ANP) (1-28), is naturally synthesized and released by the human heart in reaction to cardiac injury and mechanical stretch. This compound effectively suppresses endothelin-1 secretion in a dose-dependent manner.
T4574	Sacubitril AHU 377,AHU377,沙库必曲,AHU-377	Neprilysin	Metabolism
	Sacubitril (AHU-377) 是一种有效的NEP 抑制剂，IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。
T82932	Auriculin B Atrial natriuretic peptide(126-150)(rat),ANP (126-150) (Rat)
	Auriculin B (ANP (126-150) (Rat)) 是源自大鼠的心房钠尿肽，具备显著的血管舒张与利尿作用。
T82823	Brain Natriuretic Peptide-45, rat TFA BNP-45, rat TFA
	Brain Natriuretic Peptide-45, rat TFA (BNP-45, rat TFA) 为来源于大鼠心脏的脑利钠肽循环同源物，具有显著的降压和利尿效果。
T80438	Atrial natriuretic peptide (3-28) (human) ANP (3-28) (human)	Endothelin Receptor	GPCR/G Protein
	Atrial natriuretic peptide (3-28) (human) 是由心房心肌细胞合成并分泌的肽类激素，主要在调节血压、体液平衡及电解质稳态方面发挥作用。
TP1206	BNP-45 (rat) (TFA) (123337-89-3 free base) BNP-45 (rat) (TFA),Brain natriuretic peptide-45 rat TFA
	BNP-45 (rat) TFA is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency.
TP1209	BNP (1-32), rat TFA (133448-20-1 free base) Brain Natriuretic Peptide (BNP) (1-32), rat TFA,BNP (1-32), rat TFA
	Acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. Helps restore the body\'s sa
T21484	BNP (1-32), human	Others	Others
	BNP (1-32), human 是一种脑利钠肽。
TP1413L	Crustacean Cardioactive Peptide Acetate CCAP acetate
	Crustacean Cardioactive Peptide Acetate (CCAP acetate) 是是节肢动物中最保守和普遍存在的神经肽，在昆虫中由腹侧神经索中的保守神经元网络产生。Crustacean Cardioactive Peptide Acetate 是一种环酰胺化九肽激素，常见于昆虫，甲壳类动物和其他节肢动物中。
T4200	Sacubitril hemicalcium salt AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt	Neprilysin	Metabolism
	Sacubitril hemicalcium salt (AHU377 calcium salt) 是一种有效的 NEP 抑制剂，IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。
TP1872	Vasonatrin Peptide (VNP) Vasonatrin Peptide VNP
	Vasonatrin peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) with potent venodilating and natriuretic activity.
T30701	Candoxatrilat UK69578,UK 69578,U 73967,U-73967,U73967,UK-69578
	Candoxatrilat (U 73967, UK69578) is an active neutral endopeptidase inhibitor that reduces atrial natriuretic peptide degradation.
T76386	ANP (1-30), frog
	ANP (1-30), frog 是蛙源心房肽的多肽片段。具有利钠、利尿和血管松弛作用。
T61496	NPR-C activator 1
	NPR-C activator 1 (Compound 1) is a potent activator of natriuretic peptide receptor C (NPR-C), a receptor involved in the regulation of vascular homeostasis. It acts as a potent agonist (EC50 ~ 1 μM) of C-type natriuretic peptide (CNP), showing promising in vivo pharmacokinetic properties [1].
T82847	BNP (1-21), Pro (Human)
	BNP (1-21), Pro (Human) 是一种由21个氨基酸组成的心脏激素多肽。作为B型利钠肽(BNP)的一部分，与心房利钠肽高度同源，共同构成了心脏的双利钠肽系统。BNP 主要参与心脏发生的调节，并涉及向子宫外环境过渡的生理进程。
T70471	Cgs 26303
	Cgs 26303 is a potent non-peptidic inhibitor of neutral endopeptidase capable of protecting atrial natriuretic peptide from enzymatic degradation.
T71987	5-hydroxy Isatin
	5-hydroxy Isatin is an inhibitor of monoamine oxidase A and also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.
T78007	Vasonatrin Peptide (VNP) TFA
	Vasonatrin Peptide (VNP) TFA 是一种由心钠素 (ANP) 和C型利钠肽 (CNP) 嵌合而成的肽类化合物。它整合了CNP的静脉扩张功能、ANP的利尿效果，并展现出与ANP或CNP无关的特有动脉扩张特性。Vasonatrin Peptide TFA 透过cGMP-PKG信号途径发挥其对内质网应激介导的糖尿病心脏缺血再灌注损害的保护作用。
T81891	M65
	M65为PAC1受体特异性拮抗剂，可抑制ANP释放。
T80156	CNP-38
	CNP-38是C型钠尿肽，具有调节血压和体液平衡的生物活性。
TP1630	A-71915 TFA (132956-87-7 free base) A-71915 TFA
	A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells.
T76277	Vosoritide
	Vosoritide (BMN 111) 为改良重组CNP (C型钠尿肽) 类似物，作用于NPR-B (B型钠尿肽受体)，能有效降低FGFR3 (成纤维细胞生长因子受体 3) 活性，主要应用于软骨症和侏儒症研究领域。
T76334	Cenderitide
	Cenderitide 是一种有效的颗粒鸟酰基环化酶受体 (pGC) 激动剂。Cenderitide 是一种由 C 型利钠肽 (CNP) 与石斛利钠肽 (DNP) 的 C 端融合而成的利钠肽 (NP) 。Cenderitide 可激活 pGC-A 和 pGC-B，激活第二信使 cGMP，抑制醛固酮 (aldosterone)，在不降低血压的情况下保持 GFR 。Cenderitide 可用于心力衰竭的研究。
T38641	AP 811
	AP 811, a selective antagonist of the atrial natriuretic peptide clearance receptor (APN-CR, NPR3) with a K i value of 0.48 nM, exhibits remarkable selectivity for NPR3 over NPR1 by more than 20,000-fold. Moreover, AP 811 effectively eliminates ANP-induced pump stimulation.
T76277L	Vosoritide acetate
	Vosoritide (BMN 111) acetate，一种NPR2（利尿钠肽受体2）激动剂，作用于软骨细胞增殖与分化，促进骨骼生长。
T76037	A-71915 TFA
	A-71915 (TFA) 为一种选择性心房利钠肽受体 (ANP receptor) 抑制剂，其作用能够诱导 RINm5F 胰腺 β 细胞凋亡，并减少胰岛素释放。
T61095	SCH-42354
	SCH-42354 is a potent, orally active inhibitor of neutral endopeptidase (NEP), serving as the active form of the prodrug SCH-42495. By inhibiting NEP hydrolysis, SCH-42354 enhances the activity of atrial natriuretic peptide (ANP) and prevents the hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. Furthermore, SCH-42354 exhibits antihypertensive activity [1] [2].
T82886	Big endothelin-1 (rat 1-39)
	Big endothelin-1 (rat 1-39) 是一个由39个氨基酸残基组成的多肽。它能在清醒状态的Sprague-Dawley大鼠中诱导利尿和利钠的反应，并可导致小鼠血压上升。
T69429	Y27632 HCl hydrate
	Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepatic fibrosis in rats, increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium, affects initial heart myofibrillogenesis in cultured chick blastoderm, promotes the proliferation and cell cycle progression of cultured astrocyte from spinal cord...
T80891	Urodilatin
	Urodilatin为ANF-(99-126)的同类物，属于利尿钠调节肽。该化合物主要应用于急性肾功能衰竭、充血性心力衰竭、支气管哮喘等疾病的研究领域。
T82993	AP 811 acetate
	AP 811 acetate是一款选择性的ANP-CR（即NPR3）拮抗剂，其Ki值为0.48 nM。该化合物对NPR3的选择性是对NPR1的两万倍。此外，AP 811 acetate能够消除ANP诱导的泵激活现象。
TP2221	ANP (1-11), rat	Others	Others
	Atrial Natriuretic Peptide (ANP) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide. ANP is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. It is involved in the hom
T81444	PL-3994
	PL-3994作为NPR-A的激动剂，展现了对中性肽酶的耐药特性，具有支气管扩张效应。对预收缩豚鼠气管，PL-3994表现出浓度依赖性的弛豫作用，其IC50值为42.7 nM。

化合物

C-Type Natriuretic Peptide (CNP) (1-22), human acetate

Cat.No: T39392L

Synonym: C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)

Target: Others

C-Type Natriuretic Peptide (CNP) (1-22), human

Cat.No: TP1187

Synonym: CNP (1-22), human

Target: RAAS

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

Cat.No: TP1219

Synonym: ANP (1-28), human, porcineANP(1-28)

Brain Natriuretic Peptide-45, mouse

Cat.No: T39246

Synonym: Brain Natriuretic Peptide-45, mouse,BNP-45, mouse

Brain Natriuretic Peptide (1-32), rat acetate

Cat.No: T35832

C-Type Natriuretic Peptide (CNP) (1-22), human TFA

Cat.No: T39392

Brain Natriuretic Peptide-32 (rat) acetate

Cat.No: T83905

Synonym: BNP (14-45),B-type Natriuretic Peptide-32,Brain Natriuretic Polypeptide-32,BNP-32

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled

Cat.No: T39244

Atrial Natriuretic Peptide (ANP) (1-28), rat

Cat.No: TP1221

Synonym: Atrial natriuretic factor (1-28) (rat)

Brain Natriuretic Peptide (1-32), rat

Cat.No: TP1756

Synonym: Brain Natriuretic Peptide (BNP) (1-32), rat

Brain Natriuretic Peptide-45, rat

Cat.No: TP1207

Synonym: BNP-45 (rat),Brain natriuretic peptide-45 rat

C-Type Natriuretic Peptide (1-53), human

Cat.No: TP1581

Carperitide acetate

Cat.No: TP1220L

Synonym: 醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

Target: Endothelin Receptor

Atrial natriuretic factor (1-28) (human, porcine)

Cat.No: T41065

Synonym: Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28)

Dendroaspis Natriuretic Peptide

Cat.No: T82586

Cat.No: TP1208

Synonym: BNP-32,Brain Natriuretic Peptide-32 human,奈西立肽

Atrial natriuretic factor (1-28) (rat) TFA

Cat.No: TP1218

Synonym: Atrial Natriuretic Peptide (ANP) (1-28), rat TFA

Cat.No: TP1220

Synonym: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine

Cat.No: T4574

Synonym: AHU 377,AHU377,沙库必曲,AHU-377

Target: Neprilysin

Cat.No: T82932

Synonym: Atrial natriuretic peptide(126-150)(rat),ANP (126-150) (Rat)

Brain Natriuretic Peptide-45, rat TFA

Cat.No: T82823

Synonym: BNP-45, rat TFA

Atrial natriuretic peptide (3-28) (human)

Cat.No: T80438

Synonym: ANP (3-28) (human)

Target: Endothelin Receptor

BNP-45 (rat) (TFA) (123337-89-3 free base)

Cat.No: TP1206

Synonym: BNP-45 (rat) (TFA),Brain natriuretic peptide-45 rat TFA

BNP (1-32), rat TFA (133448-20-1 free base)

Cat.No: TP1209

Synonym: Brain Natriuretic Peptide (BNP) (1-32), rat TFA,BNP (1-32), rat TFA

BNP (1-32), human

Cat.No: T21484

Target: Others

Crustacean Cardioactive Peptide Acetate

Cat.No: TP1413L

Synonym: CCAP acetate

Sacubitril hemicalcium salt

Cat.No: T4200

Synonym: AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt

Target: Neprilysin

Vasonatrin Peptide (VNP)

Cat.No: TP1872

Synonym: Vasonatrin Peptide VNP

Cat.No: T30701

Synonym: UK69578,UK 69578,U 73967,U-73967,U73967,UK-69578

ANP (1-30), frog

Cat.No: T76386

NPR-C activator 1

Cat.No: T61496

BNP (1-21), Pro (Human)

Cat.No: T82847

Cat.No: T70471

5-hydroxy Isatin

Cat.No: T71987

Vasonatrin Peptide (VNP) TFA

Cat.No: T78007

Cat.No: T81891

Cat.No: T80156

A-71915 TFA (132956-87-7 free base)

Cat.No: TP1630

Synonym: A-71915 TFA

Cat.No: T76277

Cat.No: T76334

Cat.No: T38641

Vosoritide acetate

Cat.No: T76277L

Cat.No: T76037

Cat.No: T61095

Big endothelin-1 (rat 1-39)

Cat.No: T82886

Y27632 HCl hydrate

Cat.No: T69429

Cat.No: T80891

Cat.No: T82993

ANP (1-11), rat

Cat.No: TP2221

Target: Others

Cat.No: T81444

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