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Cat. No. Product Name Target Signaling Pathways
T2170 SKF-96365 hydrochloride

1-[2-(4-甲氧基)-2-[3-(4-甲氧基苯基)丙氧基]乙基]咪唑,SKF96365

Apoptosis; Potassium Channel; Calcium Channel; TRP/TRPV Channel; Autophagy Apoptosis; Autophagy; Membrane transporter/Ion channel; Metabolism
SKF-96365 hydrochloride (SKF96365) 是store-operated Ca2+entry 抑制剂,也是TRP channel 阻滞剂。它显著抑制豚鼠离体心脏 hERG、hKCNQ1/hKCNE1、hKir2.1 和 hKv4.3 电流,延长QTc 间期。它通过诱导结直肠癌细胞的细胞周期阻滞和凋亡起抗肿瘤作用。
T6541 Ibutilide Fumarate

Corvert Fumarate,U70226E,富马酸伊布利特

Calcium Channel; Sodium Channel Membrane transporter/Ion channel; Metabolism
Ibutilide Fumarate (U70226E) 是一种 III 类抗心律失常药物,可作用于急性心梗阻塞。
T71945 Eleclazine free base

Eleclazine, also known as GS-6615, is a selective late sodium current inhibitor. Eleclazine is potentially useful for treatment of coronary vasodilators, antiarrhythmics and vasodilators. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and end of the T-wave in the heart’s electrical cycle) in patients with long QT-3 (LQT3) syndrome. LQT3 is a genetic disorder that prolongs the heart’s QTc interval and can cause life-threatening cardiac arrhyth...
T15755 Lidoflazine

Calcium Channel Membrane transporter/Ion channel; Metabolism
Lidoflazine is a high-affinity blocker of the HERG K+ channel and is an antianginal calcium channel blocker. It carries an obvious risk of QT interval prolongation and ventricular arrhythmia.
T26763 Belaperidone

LU111995,LU-111995,LU 111995

Belaperidone is an antipsychotic drug. It has a clozapine-like receptor profile and affinities for dopamine D(4) and 5-hydroxytryptamine(2A) receptors. LU111995 prolongs the Q-T interval to a limited degree and is not arrhythmogenic over the physiological
TP2072 BeKm-1

Potent and selective KV11.1 (hERG) channel blocker. Selective for KV11.1 over a panel of 14 other potassium channels. Dose-dependently prolongs QTc interval in isolated rabbit heart.
T75953 BeKm-1 TFA

BeKm-1 TFA is a potent, selective blocker of the KV11.1 (hERG) channel, demonstrating specificity for KV11.1 over 14 other potassium channels. This compound dose-dependently prolongs the QTc interval in isolated rabbit hearts, affirming its role as a selective inhibitor.
TD0079 Texas red-X,SE

Texas Red-X succinimidyl ester,suitable for high bright Red succinimidyl fluorescence excitation/emission maximum ~ 595/615 nm.This reactive dye contains additional amino hexanoic acid and succinimide groups.This interval helps to distinguish between the

化合物

SKF-96365 hydrochloride
Cat.No: T2170
Synonym: 1-[2-(4-甲氧基)-2-[3-(4-甲氧基苯基)丙氧基]乙基]咪唑,SKF96365
Target: Apoptosis, Potassium Channel, Calcium Channel, TRP/TRPV Channel, Autophagy
Ibutilide Fumarate
Cat.No: T6541
Synonym: Corvert Fumarate,U70226E,富马酸伊布利特
Target: Calcium Channel, Sodium Channel
Eleclazine free base
Cat.No: T71945
Synonym:
Target:
Lidoflazine
Cat.No: T15755
Synonym:
Target: Calcium Channel
Belaperidone
Cat.No: T26763
Synonym: LU111995,LU-111995,LU 111995
Target:
BeKm-1
Cat.No: TP2072
Synonym:
Target:
BeKm-1 TFA
Cat.No: T75953
Synonym:
Target:
Texas red-X,SE
Cat.No: TD0079
Synonym:
Target:
TargetMol Loading
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