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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T19820 MOPS sodium salt

MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt

Others Others
MOPS sodium salt (MOPS-Na) 在生物学中常用作缓冲剂。其中MOPS 缓冲液能使哺乳动物细胞培养基的 pH 值保持稳定。
T5045 GSK4112

1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452

Autophagy Autophagy
GSK4112 (SR6452) 是一种 Rev-erbα 激动剂,EC50 为 0.4 μM。它也是一种用于核血红素受体 Rev-erbα 的细胞生物学的小分子化学探针。
T65281 Magnesium acetate tetrahydrate

Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology
Magnesium acetate tetrahydrate 是无水醋酸镁盐的水合形式。Magnesium acetate tetrahydrate 常用来合成其他化合物,可作为电解质补充剂或分子生物学实验中的试剂。
T9396 FMoc-Arg(Tos)-OH

Others Others
FMoc-Arg(Tos)-OH 是一种用于肽合成、生物化学和分子生物学的合成氨基酸。它是一种Fmoc 保护的氨基酸,作为肽和蛋白质合成的中间体,用于固相肽合成。
T9314 CC214-1

mTOR; Autophagy Autophagy; PI3K/Akt/mTOR signaling
CC214-1 是一种 mTOR 抑制剂,具有潜在的抗癌活性,抑制蛋白翻译,可诱导自噬 (autophagy)。 CC214-1 是探索 mTOR 激酶生物学的体外工具化合物,可用于研究骨髓瘤。
T1220 Ethidium bromide

EtBr,Homidium bromide,EB,溴化乙啶

AChR Neuroscience
Ethidium bromide (EB) 是一种可用作分子生物实验学中的荧光标记(核酸染色),如琼脂糖凝胶电泳。Ethidium bromide 的λEx 为300-360 nm,λEm为590 nm。
T38273 Paclobutrazol

(2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol

Antifungal Microbiology/Virology
Paclobutrazol ((R,R)-paclobutrazol) 是一种含有三唑的植物生长延缓剂,能抑制赤霉素的生物合成。Paclobutrazol 还具有抗真菌 (antifungal) 活性。Paclobutrazol 能抑制脱落酸的合成,诱导植物的耐冷性植物。Paclobutrazol 通常用于赤霉素在植物生物学中作用的研究。
T23709 alphaSYN-IN-NAB2

alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2

alphaSYN-IN-NAB2 是一种神经元保护剂,是一种由 NAB2基因编码的蛋白质。NAB2 高效且具有选择性地保护多种细胞免受 α-syn 毒性。NAB2 对依赖于 E3 泛素连接酶 Rsp5/Nedd4 的内体转运具有促进作用。NAB2 确定 α-syn 生物学中的一个可活性分子节点,该节点可以纠正其潜在病理学的多个方面,包括功能失调的内体和内质网到高尔基体囊泡的运输。NAB2参与细胞分化、凋亡和应激反应等细胞过程,可用来研究癌症、神经发育和神经元活动。
T19207 BFCAs-1

Others Others
BFCAs-1 is a polyamine polycarboxylic bifunctional chelating agent (BFCAs) with a broad range of applications in biology, chemistry, medicine and diagnostic imaging.
T40888 3-Acetamidocoumarin

3-Acetamidocoumarin, a compound significant in biology and medicine, exhibits physiological effects and is utilized in treating various conditions, including burns, brucellosis-rheumatic diseases, and cancer.
T61592 Thalidomide-piperazine hydrochloride

Thalidomide-piperazine hydrochloride is a chemical compound with potential applications in the research of leprosy and multiple myeloma. It serves as a valuable tool in developmental biology, facilitating significant discoveries in the biochemical pathways of limb development [1].
T39524 Thalidomide-NH-PEG2-C2-NH-Boc

Thalidomide-NH-PEG2-C2-NH-Boc

Thalidomide-NH-PEG2-C2-NH-Boc, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon-targeting Thalidomide ligand with a PEG linker for the synthesis of dBRD9 (compound 6). This selective BRD9 probe PROTAC degrader is utilized in researching BAF complex biology.
T69024 Homidium Cl

Homidium Chloride is the chloride salt of ethidium (a fluorochrome), Ethidium Chloride intercalates within double-stranded nucleic acids, particularly DNA. In molecular biology, the bromide salt of ethidium is used to detect and visualize DNA after electrophoresis or in cytochemical preparations. In veterinary pharmacology, it is used as a trypanosomicide. Ethidium bromide and chloride are toxic substances and potent noncompetitive antagonists of the nicotinic acetylcholine receptor.
T27068 CPI098

CPI-098,CPI 098

CPI098 is a potent and selective inhibitors for the bromodomains of CREBBP/EP300. CREBBP/EP300 bromodomains play a critical role in regulatory T cell biology. T cell recruitment to tumors is a major mechanism of immune evasion by cancer cells.
T63029 TIM-3-IN-1

TIM-3-IN-1 是能够进一步研究癌症中 TIM-3 免疫调节生物学的有用工具。
T69378 Homidium Free Base

Homidium Free Base is a trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
T19076 X-Gluc Dicyclohexylamine

5-Bromo-4-chloro-3-indolyl-beta-D-glucuronide cyclohexylammonium salt,5-溴-4-氯-3-吲哚基-beta-D-葡糖苷酸环己胺盐

Others Others
X-Gluc Dicyclohexylamine (5-Bromo-4-chloro-3-indolyl-beta-D-glucuronide cyclohexylammonium salt) 是一种检测β-葡萄糖醛酸酶的试剂,可用于分子生物学实验中对靶基因的表达进行标记和选择。
T36450 1,2-Dimyristoyl-rac-glycerol

1,2-Dimyristoyl-rac-glycerol 可促进蛋白质和脂质之间的相互作用,可用作洗涤剂或试剂。可用于甘油脂的代谢和代谢途径的细胞生物学实验等。
T69506 dBRD4-BD1

dBRD4-BD1 is a selective BRD4 bromodomain inhibitor. dBRD4-BD1 can selectively degrade BRD4 (DC50 = 280 nM). Notably, dBRD4-BD1 upregulates BRD2/3, a result not observed with degraders using pan-BET ligands. Designing BRD4 selectivity up front enables analysis of BRD4 biology without wider BET-inhibition and simplifies designing BRD4-selective heterobifunctional molecules, such as degraders with new E3 recruiting ligands or for additional probes beyond degraders.
T31123 cvxIAA

convex IAA,5-(3-MeOPh)-IAA

cvxIAA is an orthogonal auxin-TIR1 receptor pair. cvxIAA triggers auxin signaling without interfering with endogenous auxin or TIR1/AFBs. cvxIAA hijacked the downstream auxin signaling in vivo both at the transcriptomic level and in specific developmental
T74470 3'Ome-m7GpppAmpG ammonium

3'Ome-m7GpppAmpG ammonium 是一种三核苷酸帽类似物,含锁核酸(LNA)分子,具显著翻译效率。作为潜在的分子生物学工具,3'Ome-m7GpppAmpG ammonium 在mRNA疫苗、mRNA转染领域应用广泛,涵盖蛋白质生产、基因治疗以及抗癌免疫等方面。
T74469 3'Ome-m7GpppAmpG

3'Ome-m7GpppAmpG为具有锁核酸(LNA)分子的三核苷酸帽类似物,显示出显著的翻译效率。作为mRNA疫苗和mRNA转染领域的潜在分子生物学工具,3'Ome-m7GpppAmpG适用于蛋白质生产、基因治疗和抗癌免疫等应用。
T76160 Nuclease P1

Nuclease P1 (核酸酶 P1) 是一种单链特异性核酸内切酶,它将核酸水解为 5'-单核苷酸,并切割双链核酸的单链区域。Nuclease P1 是分子生物学领域著名的单链特异性核酸酶之一,广泛应用于制药和食品行业。
T38071 HPF

The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases.[1] There are a number of fluorescent reagents, such as 2,7-dichlorodihydrofluorescein (DCDHF), that can be used to detect free radicals, but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2). [2] HPF is a cell-permeable aroma...
T35498 β-Amyloid (1-14),mouse,rat

β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-secretases. β-Amyloid (1-14),mouse,rat accumulation in the brain is proposed to be an early toxic event in the pathogenesis of Alzheimer’s disease, which is the most common form of dementia associated with plaques and tangles in the brain[1]. [1]. Chen GF, et al. Amyloid beta: stru...
T37583 XTT (sodium salt hydrate)

XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator.1,2It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.3 1.Berridge, M.V., Tan, A.S., and Herst, P.M.Tetrazolium dyes as tools in cell biology: New insights into their cellular reductionBiotechnol. Ann. Rev.11127-152(2005) 2.Berridge, M.V., and Tan, A.S.Trans-plas...
T36709 N’-Nitrosonornicotine

N’-Nitrosonornicotine is a tobacco-specific N-nitrosamine and carcinogen that has been found in unburned tobacco and cigarette smoke.1It induces the formation of DNA adducts in isolated rat nasal mucosa and esophagus. N’-Nitrosonornicotine induces tumor formation in rat esophagus and nasal cavity, mouse lung, forestomach, and trachea, and hamster trachea and forebrain. Urinary levels of N’-nitrosonornicotine are positively correlated with the risk of esophageal cancer in smokers.2 1.Hecht, S....
T37736 N-cis-hexadec-9Z-enoyl-L-Homoserine lactone

N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone

Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of whic...
T37741 N-hexadecanoyl-L-Homoserine lactone

C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which...

化合物

MOPS sodium salt
Cat.No: T19820
Synonym: MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt
Target: Others
GSK4112
Cat.No: T5045
Synonym: 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452
Target: Autophagy
Magnesium acetate tetrahydrate
Cat.No: T65281
Synonym:
Target: Endogenous Metabolite, Antibacterial
FMoc-Arg(Tos)-OH
Cat.No: T9396
Synonym:
Target: Others
CC214-1
Cat.No: T9314
Synonym:
Target: mTOR, Autophagy
Ethidium bromide
Cat.No: T1220
Synonym: EtBr,Homidium bromide,EB,溴化乙啶
Target: AChR
Paclobutrazol
Cat.No: T38273
Synonym: (2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol
Target: Antifungal
alphaSYN-IN-NAB2
Cat.No: T23709
Synonym: alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2
Target:
BFCAs-1
Cat.No: T19207
Synonym:
Target: Others
3-Acetamidocoumarin
Cat.No: T40888
Synonym:
Target:
Thalidomide-piperazine hydrochloride
Cat.No: T61592
Synonym:
Target:
Thalidomide-NH-PEG2-C2-NH-Boc
Cat.No: T39524
Synonym: Thalidomide-NH-PEG2-C2-NH-Boc
Target:
Homidium Cl
Cat.No: T69024
Synonym:
Target:
CPI098
Cat.No: T27068
Synonym: CPI-098,CPI 098
Target:
TIM-3-IN-1
Cat.No: T63029
Synonym:
Target:
Homidium Free Base
Cat.No: T69378
Synonym:
Target:
X-Gluc Dicyclohexylamine
Cat.No: T19076
Synonym: 5-Bromo-4-chloro-3-indolyl-beta-D-glucuronide cyclohexylammonium salt,5-溴-4-氯-3-吲哚基-beta-D-葡糖苷酸环己胺盐
Target: Others
1,2-Dimyristoyl-rac-glycerol
Cat.No: T36450
Synonym:
Target:
dBRD4-BD1
Cat.No: T69506
Synonym:
Target:
cvxIAA
Cat.No: T31123
Synonym: convex IAA,5-(3-MeOPh)-IAA
Target:
3'Ome-m7GpppAmpG ammonium
Cat.No: T74470
Synonym:
Target:
3'Ome-m7GpppAmpG
Cat.No: T74469
Synonym:
Target:
Nuclease P1
Cat.No: T76160
Synonym:
Target:
HPF
Cat.No: T38071
Synonym:
Target:
β-Amyloid (1-14),mouse,rat
Cat.No: T35498
Synonym:
Target:
XTT (sodium salt hydrate)
Cat.No: T37583
Synonym:
Target:
N’-Nitrosonornicotine
Cat.No: T36709
Synonym:
Target:
N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
Cat.No: T37736
Synonym: N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
Target:
N-hexadecanoyl-L-Homoserine lactone
Cat.No: T37741
Synonym: C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone
Target:
Cat. No. Product Name Target Signaling Pathways
T65128 Tartaric acid disodium dihydrate

Disodium L-(+)-Tartrate Dihydrate

Phosphatase; Endogenous Metabolite Metabolism
Tartaric acid disodium dihydrate (Disodium L-(+)-Tartrate Dihydrate) 常用来制作分子生物学和细胞培养中的缓冲液,。Tartaric acid disodium dihydrate 是酸性磷酸酶抑制剂, 可增加秋水仙碱结合 tubulin1的概率。
T75743 HA Peptide TFA

HA Peptide (TFA) 为源自人类流感血凝素 (HA) 的九氨基酸多肽, 在细胞生物学与生物化学领域内广泛应用于目标蛋白的分离、纯化、检测及追踪。

天然产物

Tartaric acid disodium dihydrate
Cat.No: T65128
Synonym: Disodium L-(+)-Tartrate Dihydrate
Target: Phosphatase, Endogenous Metabolite
HA Peptide TFA
Cat.No: T75743
Synonym:
Target:
TargetMol Loading
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