首页工具

登录

搜索结果

Search Results for " biliary "

21

抑制剂 & 化合物

6

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T0396	Pipemidic acid 吡哌酸,Acido pipemidico	Antibacterial; Antibiotic	Microbiology/Virology
	Pipemidic acid (Acido pipemidico) 是一种新型抗菌剂，对革兰氏阴性菌和某些革兰氏阳性细菌具有活性，可研究肠道、泌尿和胆道感染。
T3978	Linerixibat GSK2330672,Iinerixibat	HBV	Microbiology/Virology
	Linerixibat (GSK2330672) 是高效的、不可吸收的、具有口服活性的顶端钠依赖性胆汁酸转运蛋白 (ASBT) 抑制剂，对人ASBT 的IC50为 42 nM。它是一种降脂剂，具有用于 2 型糖尿病和原发性胆源性胆管炎的研究潜力。
T19239	Cicloxilic acid Cycloxilic acid	Others	Others
	Cicloxilic acid（Cycloxilic acid）具有利胆活性，抑制胆汁胆固醇的输出。
T73718	MDCG sodium NOX 100 sodium,N-methyl-N-dithiocarboxyglucamine sodium	Endogenous Metabolite	Metabolism
	MDCG sodium (N-methyl-N-dithiocarboxyglucamine sodium) 是一种金属螯合剂，可促进Cd的胆道排泄。
T16376	Odevixibat A4250	Others	Others
	Odevixibat (A4250) (A4250) 是一种有效的选择性回肠胆汁酸转运蛋白 (IBAT) 抑制剂。Odevixibat (A4250) 可减轻小鼠模型中的胆汁淤积性肝和胆管损伤。Odevixibat (A4250)可用于原发性胆汁性肝硬化的研究。
T26943	CAP-7.1 CAP7.1
	CAP-7.1, a DNA topoisomerase inhibitor, is used potentially for the treatment of biliary cancer and non-small cell lung cancer.
T32180	Iophendylate Maiodil,Panthopaque,Iodophendylate,Ethiodan,Ioglunide
	Iofendylate is a molecule used as a contrast medium. It is an absorbable iodized fatty acid of low viscosity used for roentgenography of the spinal cord, biliary tree, sinuses, and body cavities.
T23923	Cyclobutyrol BRN 2209058,BRN-2209058,BRN2209058,Cyclobutyrolum,JL 130
	Cyclobutyrol is a choleretic agent. It also inhibits biliary lipid secretion.
T30904	Cholecystokinin-J CCK-J
	Cholecystokinin-J can be used in cholecystography, radiomanometry and biliary cinematography.
T71403	Cyclobutyrol sodium salt
	Cyclobutyrol sodium salt is a choleretic agent which also inhibits biliary lipid secretion.
T33314	Methantheline Bromide Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
	Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancreatitis, gastritis, biliary dysmotil
T31820	Fluorescein lisicol NRL972,NRL-972,NRL 972
	Fluorescein lisicol, as an investigational marker of hepatic biliary transporter function, is a fluorescent-labeled bile salt.
T27167	Diclofenac Acyl Glucuronide
	Diclofenac Acyl Glucuronide is a major biliary metabolite of Diclofenac (GLXC-07892), a nonsteroidal antiinflammatory drug and COX inhibitor.
T32179	Ioglycamic acid BE-419,Ioglycamide,BE419,BE 419
	Iodoxylic acid, a mixture of meglumine and sodium salts, is used to visualize the biliary tract as a radiopaque diagnostic aid.
T25325	Dicyclonon LAB 145-138H,BAS 145-138
	Dicyclonon is a muscarinic antagonist utilized as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It has some local anesthetic properties and is utilized in biliary, gastrointestinal,
T6582L	Mezlocillin Bay-f 1353,Meslocillin,Melocin,Baypen,Mezlin
	Meloxicillin is a broad-spectrum penicillin antibiotic that is active against both Gram-negative bacteria and some Gram-positive bacteria. Unlike most other broad-spectrum penicillin, it is excreted by the liver and can therefore be used to treat biliary
T63793	Tauro-ω-muricholic acid sodium
	Tauro-ω-muricholic acid sodium (TωMCA sodium) 是一种tauro-α-muricholic acid 的类似物，是来源于肝脏的胆汁酸。Tauro-ω-muricholic acid sodium 能用作早发性新生儿败血症 (EOS) 和胆汁淤积的血清标志物。
T41150	EMD 527040 hydrochloride
	EMD 527040 hydrochloride 是一种有效的整合素α V β 6抑制剂。EMD 527040 hydrochloride 对α V β 6与纤维连接蛋白的结合和表达α V β 6的细胞与纤维连接蛋白的附着有抑制作用，IC 50值分别为6 nM 和1.6 μM。EMD 527040 hydrochloride 在胆道纤维化动物模型中显示出抗纤维化活性，并在体内具有活性。
T73155	BMS-986339
	BMS-986339 是一种具有口服活性的FXR 激动剂。BMS-986339 可与 His298 和 ASN287 残基形成氢键。BMS-986339 可用于原发性胆汁性肝硬化 (PBC)、原发性硬化性胆管炎 (PSC)、非酒精性脂肪性肝炎 (NASH)，和抗纤维化研究。
T73414	EDP-305
	EDP-305是一种具有选择性的口服farnesoid X受体(FXR)激动剂，其EC50值分别为34 nM(CHO细胞嵌合性FXR)和8 nM(HEK细胞全长FXR)。该化合物展现了强大且持久的抗纤维化效果，并适用于原发性胆道胆管炎(PBC)与非酒精性脂肪性肝炎(NASH)的研究。
T83422	1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine
	1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine 是一种由磷酸甘油、胆碱和棕榈酸构成的甘油磷酸胆碱类化合物，通常在体内氧化应激位点累积。该化合物是 B 类清道夫受体 (CD36和SR-BI) 的有效配体，特别是氧化磷脂 oxPC(CD36)。此外，氧化磷脂 (oxPLs) 在肿瘤细胞凋亡中扮演关键角色，并且在恶性胆管狭窄疾病中可能会有所增加。

化合物

Cat.No: T0396

Synonym: 吡哌酸,Acido pipemidico

Target: Antibacterial, Antibiotic

Cat.No: T3978

Synonym: GSK2330672,Iinerixibat

Target: HBV

Cicloxilic acid

Cat.No: T19239

Synonym: Cycloxilic acid

Target: Others

Cat.No: T73718

Synonym: NOX 100 sodium,N-methyl-N-dithiocarboxyglucamine sodium

Target: Endogenous Metabolite

Cat.No: T16376

Synonym: A4250

Target: Others

Cat.No: T26943

Synonym: CAP7.1

Cat.No: T32180

Synonym: Maiodil,Panthopaque,Iodophendylate,Ethiodan,Ioglunide

Cat.No: T23923

Synonym: BRN 2209058,BRN-2209058,BRN2209058,Cyclobutyrolum,JL 130

Cholecystokinin-J

Cat.No: T30904

Synonym: CCK-J

Cyclobutyrol sodium salt

Cat.No: T71403

Methantheline Bromide

Cat.No: T33314

Synonym: Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide

Fluorescein lisicol

Cat.No: T31820

Synonym: NRL972,NRL-972,NRL 972

Diclofenac Acyl Glucuronide

Cat.No: T27167

Ioglycamic acid

Cat.No: T32179

Synonym: BE-419,Ioglycamide,BE419,BE 419

Cat.No: T25325

Synonym: LAB 145-138H,BAS 145-138

Cat.No: T6582L

Synonym: Bay-f 1353,Meslocillin,Melocin,Baypen,Mezlin

Tauro-ω-muricholic acid sodium

Cat.No: T63793

EMD 527040 hydrochloride

Cat.No: T41150

Cat.No: T73155

Cat.No: T73414

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine

Cat.No: T83422

Cat. No.	Product Name	Target	Signaling Pathways
T13522	7-Ketolithocholic acid 3α-Hydroxy-7-oxo-5β-cholanic acid	Endogenous Metabolite	Metabolism
	7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and serves to suppress the production of endogenous bile acid and the secretion of biliary cholesterol.
TJA2398	Taurodeoxycholic acid sodium hydrate Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt,牛磺猪去氧胆酸	Apoptosis; Caspase	Apoptosis; Proteases/Proteasome
	Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate) 通过阻断钙介导的凋亡通路和 Caspase-12的活化来阻止细胞凋亡。它可用于原发性胆汁性肝硬化、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤积和肌萎缩侧索硬化症。
T2532	Tauroursodeoxycholate Taurolite,牛磺熊去氧胆酸,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis; ERK; P450; Caspase; Endogenous Metabolite	Apoptosis; MAPK; Metabolism; Proteases/Proteasome
	Tauroursodeoxycholate (UR 906)，又称 ursodoxicoltaurine，是一种高度亲水性的三级胆汁酸，在人体内以低浓度产生。Tauroursodeoxycholate 是 ursodeoxycholic acid 更亲水的形式，而 ursodeoxycholic acid 是人类体内自然产生的更丰富的胆汁酸。Tauroursodeoxycholate 正在研究用于几种疾病，如原发性胆汁性肝硬化(PBC)、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤滞和肌萎缩性侧索硬化症。
T30451	Biliatresone
	Biliatresone is a very rare natural isoflavone-related 1, 2-diaryl-2-allenone found in Dysphania Glomulifera and D. littoralis. It has been found to cause extrahepatic biliary atresia in zebra fish models.
T7475	S-Adenosyl-L-methionine AdoMet,Ademetionine,SAMe,S-Adenosyl methionine,S-腺苷-L-蛋氨酸	Others; Endogenous Metabolite	Metabolism; Others
	S-Adenosyl-L-methionine (Ademetionine) 是一种具有有效的抗抑郁和减轻疼痛作用的膳食补充剂，是通过蛋氨酸腺苷转移酶的作用由蛋氨酸和 ATP 内源性生产的，是一种重要的口服具有活力的甲基供体，能够用于肝病和骨关节炎的研究。
T37770	Taurohyodeoxycholic acid
	Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats.2Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats.3THDCA also reduces myeloperoxidase activity, expressi...

天然产物

7-Ketolithocholic acid

Cat.No: T13522

Synonym: 3α-Hydroxy-7-oxo-5β-cholanic acid

Target: Endogenous Metabolite

Taurodeoxycholic acid sodium hydrate

Cat.No: TJA2398

Synonym: Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt,牛磺猪去氧胆酸

Target: Apoptosis, Caspase

Tauroursodeoxycholate

Cat.No: T2532

Synonym: Taurolite,牛磺熊去氧胆酸,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA

Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite

Cat.No: T30451

S-Adenosyl-L-methionine

Cat.No: T7475

Synonym: AdoMet,Ademetionine,SAMe,S-Adenosyl methionine,S-腺苷-L-蛋氨酸

Target: Others, Endogenous Metabolite

Taurohyodeoxycholic acid

Cat.No: T37770

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼