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Cat. No.	Product Name	Target	Signaling Pathways
T1278	Astemizole Laridal,Histaminos,Paralergin,阿司咪唑	Potassium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Astemizole (Laridal) 是一种长效、非镇静抗组胺药，用于治疗季节性过敏性鼻炎、哮喘、过敏性结膜炎和慢性特发性荨麻疹。它是组胺 H1 受体的拮抗剂，IC50值为 4 nM，还阻断 hERG K+通道，IC50值为 0.9 nM，具有抗胆碱能和止痒作用。
T6562	Latrepirdine dihydrochloride Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin	Beta Amyloid; 5-HT Receptor; Adrenergic Receptor; GluR; Autophagy; Histamine Receptor	Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Latrepirdine dihydrochloride (Dimebolin dihydrochloride) 是一种具有口服活性和神经活性的多种药物靶点的拮抗剂，可刺激淀粉样前体蛋白分解代谢和 β-淀粉样蛋白分泌。
T4526	Piperoxan hydrochloride dl-Piperoxan hydrochloride,盐酸哌罗克生,Benodaine hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Piperoxan hydrochloride (Benodaine hydrochloride) 是第一代抗组胺剂，是一种 α2肾上腺素受体拮抗剂。
T4563	Thonzylamine neohetramine,松齐拉敏	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Thonzylamine (neohetramine) 是可口服的H1组胺受体拮抗剂，具有抗组胺和抗过敏特性，可用于鼻充血、过敏性结膜炎和其他过敏性疾病的研究。
T21419	Diphenhydramine 苯海拉明,Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Diphenhydramine (Syntedril) 是第一代具有抗胆碱能作用的H1 受体拮抗剂，它能透过血脑屏障。
T21390	Fexofenadine Carboxyterfenadine,Telfast,非索非那定,MDL 16.455,Allegra	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Fexofenadine (Carboxyterfenadine) 是一种抗组胺药物，用于治疗过敏症状，如鼻塞、花粉热和荨麻疹。与第一代抗组胺药相比，它通过血脑屏障并引起镇静的能力较差。
T25413	Fenethazine RP 3015,Lisergan,Phenetazine,RP-3015,Ethysene
	Fenethazine is an effective antihistamine used as an antiallergic drug.
T24851	Talastine HCl HL-2186,Talastine hydrochloride,HL2186,Ahanon,HL 2186
	Talastine is an antihistamine drug.
T24575	Oxetorone fumarate L-6257,L6257,L 6257,Nocertone
	Oxetorone fumarate is a serotonin antagonist, antihistamine, and alpha-blocker. It was used as an antimigraine drug.
T33978	Phenindamine Tartrate Pernovine,Thephorin,Nolahist,Phenindamine,Plegine
	Phenindamine Tartrate is an antihistamine and anticholinergic drug closely related to cyproheptadine. It is used to treat symptoms of the common cold and allergies, such as sneezing, itching, rashes, and hives.
T69012	Cinnarizine clofibrate
	Cinnarizine clofibrate is a calcium channel protein inhibitor as well as an antihistamine channel blocker. The compound is a drug derivative of piperazine. Cinnarizine is used for the control of vomiting due to motion sickness. It acts by interfering with the signal transmission between vestibular apparatus of the inner ear and the vomiting centre of the hypothalamus
T69516	Thenalidine tartrate
	Thenalidine is an antihistamine with anticholinergic properties used as an antipruritic drug. It was withdrawn from the US, Canadian, and UK markets due to a risk of neutropenia. Thenalidine is an antagonist of the H1-receptor.
T71537	Tofenacin hydrochloride
	Tofenacin hydrochloride is an antidepressant drug with a tricyclic-like structure. It acts as a serotonin-norepinephrine reuptake inhibitor, and based on its close relation to orphenadrine, may also possess anticholinergic and antihistamine properties. Tofenacin is also the major active metabolite of orphenadrine and likely plays a role in its beneficial effects against depressive symptoms seen in Parkinson's disease patients.
T70487	Tofenacin (free base)
	Tofenacin (free base) is an antidepressant drug with a tricyclic-like structure. It acts as a serotonin-norepinephrine reuptake inhibitor, and based on its close relation to orphenadrine, may also possess anticholinergic and antihistamine properties. Tofenacin is also the major active metabolite of orphenadrine and likely plays a role in its beneficial effects against depressive symptoms seen in Parkinson's disease patients.
T70247	Clemizole sulfate
	Clemizole sulfate is a drug in clinical development for the treatment of hepatitis C virus (HCV) infection. Clemizole is a novel inhibitor of TRPC5 channels. Clemizole is an H1 antagonist. Clemizole, an antihistamine drug that was once widely used for treatment of allergic disease, was recently discovered to be a potent inhibitor (IC50, 24 nM) of the interaction between an HCV protein (NS4B) and HCV RNA. Although clemizole was widely used during the 1950s and 1960s, this was before contemporary ...

化合物

Cat.No: T1278

Synonym: Laridal,Histaminos,Paralergin,阿司咪唑

Target: Potassium Channel, Histamine Receptor

Latrepirdine dihydrochloride

Cat.No: T6562

Synonym: Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin

Target: Beta Amyloid, 5-HT Receptor, Adrenergic Receptor, GluR, Autophagy, Histamine Receptor

Piperoxan hydrochloride

Cat.No: T4526

Synonym: dl-Piperoxan hydrochloride,盐酸哌罗克生,Benodaine hydrochloride

Target: Adrenergic Receptor

Cat.No: T4563

Synonym: neohetramine,松齐拉敏

Target: Histamine Receptor

Diphenhydramine

Cat.No: T21419

Synonym: 苯海拉明,Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255

Target: Histamine Receptor

Cat.No: T21390

Synonym: Carboxyterfenadine,Telfast,非索非那定,MDL 16.455,Allegra

Target: Histamine Receptor

Cat.No: T25413

Synonym: RP 3015,Lisergan,Phenetazine,RP-3015,Ethysene

Cat.No: T24851

Synonym: HL-2186,Talastine hydrochloride,HL2186,Ahanon,HL 2186

Oxetorone fumarate

Cat.No: T24575

Synonym: L-6257,L6257,L 6257,Nocertone

Phenindamine Tartrate

Cat.No: T33978

Synonym: Pernovine,Thephorin,Nolahist,Phenindamine,Plegine

Cinnarizine clofibrate

Cat.No: T69012

Thenalidine tartrate

Cat.No: T69516

Tofenacin hydrochloride

Cat.No: T71537

Tofenacin (free base)

Cat.No: T70487

Clemizole sulfate

Cat.No: T70247

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