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Search Results for " antibacterial action "

18

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T20766	Sulfisoxazole acetyl Gantrisin,Acetylsulfisoxazole,Gantrisin Pediatric,Lipo Gantrisin,乙酰磺胺异噁唑	Antibacterial	Microbiology/Virology
	Sulfisoxazole acetyl (Gantrisin) 是 Sulfisoxazole 的一种衍生物，是口服有效的二氢蝶酸合酶抑制剂。Sulfisoxazole acetyl 显示出抗菌作用。
T11007L	Levofloxacin Hydrochloride Impurity A Levofloxacin Hydrochloride Impurity A(117707-40-1 Free base),左氧氟沙星杂质A(盐酸盐)	Antibacterial	Microbiology/Virology
	Levofloxacin Hydrochloride Impurity A 是一种喹诺酮类药物，具有广谱抗菌作用。
T0500	Chloroxine Capitrol,氯喔星	Antibacterial; Antibiotic	Microbiology/Virology
	Chloroxine (Capitrol) 是重要的 8-羟基喹啉衍生物之一，有抗细菌，抗真菌，抗原生动物和抗阿米巴虫活性，可研究肠道阿米巴病，还可研究头皮屑和头皮脂溢性皮炎。
T1482	Ciclopirox 环吡酮,HOE296b,环吡酮胺	ATPase; Ferroptosis; Antibacterial; Autophagy; Antifungal	Apoptosis; Autophagy; Membrane transporter/Ion channel; Microbiology/Virology
	Ciclopirox (HOE296b) 是一种合成的抗真菌剂，可研究浅表真菌病。
T28574	Ro 24-4383 Ro 244383
	Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.
T61284	Antibacterial agent 94
	Antibacterial agent 94 (compound 5b) is a highly effective antibacterial agent that demonstrates strong activity against various bacterial strains. Notably, Antibacterial Agent 94 is capable of eradicating MRSA persisters, highlighting its potential as a therapeutic solution. Its mechanism of action involves interference with the bacterial membrane and disruption of the phosphatidylglycerol (PG) synthesis pathway [1].
T28598	Ro-23-9424 Ro 239424,Ro23-9424
	Ro-23-9424 is a dual-action cephalosporin with a fleroxacin esterified at the 3' position and aminothiazolylmethoxyimino-type side chain at the 7 position. Ro-23-9424 has broad and potent antibacterial activity in vitro and in vivo.
T62740	Antibacterial agent 110
	Antibacterial agent 110 (Compound 4e) 是一种有效的抗细菌 (antibacterial) 剂，作用于 P. aeruginosa (MIC: 1 μg/ml)。Antibacterial agent 110 可以使代谢停滞和细胞内氧化应激，并阻碍 DNA 复制。Antibacterial agent 110 可以破坏细胞膜，具有良好的抗菌膜作用。
T68998	Parconazole Free Base
	Parconazole Free Base is used in veterinary as an oral fungicide with a broad-spectrum activity against dermatophytes, yeasts, and others fungi. This compound does not have any antibacterial effect. The mechanism of action involves inhibition of the fungal cytochrome P450 dependent 14alpha-dimethylation of lanosterol to ergosterol.
T14359	AVX 13616	Others	Others
	AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens. IC50 value: 2-4 ug/ml (MICs) Target: antibacterial agent AVX13616 was as active as mupirocin i
T82343	Gamma-Glutamyl Transferase-IN-1
	Gamma-Glutamyl Transferase-IN-1 (compound 4de) 是一种 β-羰基酰肼类抑制剂，靶向谷氨酰转移酶，具有抗真菌和抗菌活性。它通过促进活性氧积累、破坏细胞膜和失调组蛋白乙酰化来发挥作用。
T75500	Batzelladine D
	Batzelladine D (Compound 1) 是一种 Pdr5p 转运蛋白催化活性和功能活性的抑制剂。Batzelladine D 抑制 Pdr5p ATPase 活性，IC50值为 7.1 µM。Batzelladine D 具有抗真菌 (antifungal)、抗寄生虫 (antiparasitic)、抗病毒 (antiviral)、抗细菌 (antibacterial) 和抗肿瘤活性。
T69350	Ethionamide HCl
	Ethionamide HCl is the salt form of Ethionamide, a second-line antitubercular agent that inhibits mycolic acid synthesis. Ethionamide is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and ...
T83703	BLP-3 TFA Bombin-like Peptide 3
	BLP-3是一种在X. laevis皮肤中表达的内源性多肽，具有抗菌特性。在20 µg/ml的浓度下对N. meningitidis、N. gonorrhoeae、N. lactamica和N. cinerea有效。BLP-3折叠成α-螺旋结构，能插入并破坏类细菌膜。
T82342	Gamma-Glutamyl Transferase-IN-2
	Gamma-Glutamyl Transferase-IN-2 (compound 4dq)，一种β-羰基酰肼类抑制剂，针对谷氨酰转移酶 (gamma-glutamyl transferase)，展现其抗真菌与抗菌活性。该化合物通过诱导活性氧积累、破坏细胞膜以及干扰组蛋白乙酰化来发挥其生物学效应。
T75296	Pazufloxacin
	Pazufloxacin (T-3761)是氟喹诺酮类广谱抗生素。
T74790	FtsZ-IN-7
	FtsZ-IN-7 是一种有效的FtsZ 抑制剂，可促进 FtsZ 聚合并抑制 FtsZ 的 GTPase 活性。因此，FtsZ-IN-7 抑制细菌分裂导致细菌细胞死亡。FtsZ-IN-7 显示出杀菌活性，没有明显的引发细菌耐药性的趋势以及快速杀菌特性。并且 FtsZ-IN-7 对哺乳动物细胞表现出低溶血活性和细胞毒性。
T36021	Flumequine-13C3 Flumequine-13C3
	Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, andK. pneumoniae(MICs = 1-100 μg/ml). Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 μg/ml).2It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.3In vivo, fl...

化合物

Sulfisoxazole acetyl

Cat.No: T20766

Synonym: Gantrisin,Acetylsulfisoxazole,Gantrisin Pediatric,Lipo Gantrisin,乙酰磺胺异噁唑

Target: Antibacterial

Levofloxacin Hydrochloride Impurity A

Cat.No: T11007L

Synonym: Levofloxacin Hydrochloride Impurity A(117707-40-1 Free base),左氧氟沙星杂质A(盐酸盐)

Target: Antibacterial

Cat.No: T0500

Synonym: Capitrol,氯喔星

Target: Antibacterial, Antibiotic

Cat.No: T1482

Synonym: 环吡酮,HOE296b,环吡酮胺

Target: ATPase, Ferroptosis, Antibacterial, Autophagy, Antifungal

Cat.No: T28574

Synonym: Ro 244383

Antibacterial agent 94

Cat.No: T61284

Cat.No: T28598

Synonym: Ro 239424,Ro23-9424

Antibacterial agent 110

Cat.No: T62740

Parconazole Free Base

Cat.No: T68998

Cat.No: T14359

Target: Others

Gamma-Glutamyl Transferase-IN-1

Cat.No: T82343

Cat.No: T75500

Ethionamide HCl

Cat.No: T69350

Cat.No: T83703

Synonym: Bombin-like Peptide 3

Gamma-Glutamyl Transferase-IN-2

Cat.No: T82342

Cat.No: T75296

Cat.No: T74790

Flumequine-13C3

Cat.No: T36021

Synonym: Flumequine-13C3

Cat. No.	Product Name	Target	Signaling Pathways
T1262	Tazobactam Tazobactamum,Tazobactam acid,他唑巴坦酸,YTR-830H,CL-298741,他唑巴坦	Antibacterial; Antibiotic	Microbiology/Virology
	Tazobactam (YTR-830H) acid 是一种具有抗菌活性的β-内酰胺酶抑制剂。
T5707	3-O-Methylgalangin 3-Methylgalangin,GALANGIN-3-METHYLETHER,高良姜素 3-O-甲醚,高良姜素-3-甲醚	Antibacterial	Microbiology/Virology
	3-O-Methylgalangin (GALANGIN-3-METHYLETHER) 是一种来源于高良姜根茎的天然黄酮，具有抗菌活性，抑制胰腺脂肪酶。
T1165	Ethionamide Bayer 5312,乙硫异烟胺,2-ethylthioisonicotinamide,Ethinamide	Dehydrogenase; CAT; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology; oxidation-reduction
	Ethionamide (2-ethylthioisonicotinamide) 是一种抗结核抗生素。
T1153	Trimethoprim NIH 204,BW 56-72,甲氧苄啶,NSC-106568	DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Trimethoprim (NSC-106568) 是抑菌抗生素，也是具有口服活性的二氢叶酸还原酶抑制剂。它对多种革兰氏阳性和革兰氏阴性需氧细菌具有活性，可用于尿路感染，肺孢子菌肺炎和志贺氏菌病的研究。
T1235L	Lincomycin U 10149,U10149,U-10149
	Lincomycin is a lincosamide antibiotic that comes from the actinomycete Streptomyces lincolnensis. Although similar in structure, antibacterial spectrum, and mechanism of action to macrolides, lincomycin is also effective against other organisms including
T81080	Strictinin
	Strictinin 是从普洱茶 (Pu'er teas) 分离得到的酚类化合物，展现出潜在的抗病毒、抗菌和通便活性。这些活性是由于它加速小肠转运所致，并非因增强胃排空、增加食物摄入或诱导大鼠腹泻而发挥作用。

天然产物

Cat.No: T1262

Synonym: Tazobactamum,Tazobactam acid,他唑巴坦酸,YTR-830H,CL-298741,他唑巴坦

Target: Antibacterial, Antibiotic

3-O-Methylgalangin

Cat.No: T5707

Synonym: 3-Methylgalangin,GALANGIN-3-METHYLETHER,高良姜素 3-O-甲醚,高良姜素-3-甲醚

Target: Antibacterial

Cat.No: T1165

Synonym: Bayer 5312,乙硫异烟胺,2-ethylthioisonicotinamide,Ethinamide

Target: Dehydrogenase, CAT, Antibacterial, Antibiotic

Cat.No: T1153

Synonym: NIH 204,BW 56-72,甲氧苄啶,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

Cat.No: T1235L

Synonym: U 10149,U10149,U-10149

Cat.No: T81080

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