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29

抑制剂 & 化合物

4

天然产物

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Cat. No. Product Name Target Signaling Pathways
T0893 Tinidazole

替硝唑,CP12574

Antibacterial; Antibiotic Microbiology/Virology
Tinidazole (CP12574) 是一种对厌氧菌和原生动物具有选择性抗菌活性的 5-硝基咪唑,是一种具有口服活性的抗菌剂。
T0116 Balofloxacin

DNA gyrase; Antibacterial; Antibiotic DNA Damage/DNA Repair; Microbiology/Virology
Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素,可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成,对革兰氏阴性,革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道,肠道和泌尿道感染。
T2279 Tizoxanide

替唑尼特,Desacetyl-nitazoxanide,TIZ

Antiviral; HIV Protease; Antibacterial; Autophagy Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Tizoxanide (Desacetyl-nitazoxanide) 是 Nitazoxanide 活性代谢物,有抗HIV-1的活性。Nitazoxanide 可抗细菌和多种病毒复制。
T4991 Ertapenem sodium

厄他培南钠,MK-826,L-749345,尔他培南钠

Antibacterial; Antibiotic Microbiology/Virology
Ertapenem sodium (MK-826) 是碳青霉烯,是一种 β-内酰胺抗生素,具有广谱抗菌活性。
T1283 Clinafloxacin

克林沙星,PD 127391,CI-960,AM-1091

Antibacterial; Antibiotic Microbiology/Virology
Clinafloxacin (CI-960) 是一种高效广谱氟喹诺酮类抗生素,抑制革兰氏阳性、革兰氏阴性和厌氧病原体。它对金黄色葡萄球菌的 DNA 促旋酶和拓扑异构酶 IV 有抑制作用,IC50值分别为 0.92 µg/ml 和 1.62 µg/ml。
T6706 Ticarcillin sodium

Ticarpen hydrate,Aerugipen hydrate,替卡西林单钠盐单水合物,BRL 2288,AB 2288,Monapen

Others; Antibacterial; Antibiotic Microbiology/Virology; Others
Ticarcillin sodium (Aerugipen hydrate) 主要用于抗革兰氏阴性菌, 也能用于研究嗜麦芽感染。
T12096L Morinidazole

Antibacterial Microbiology/Virology
Morinidazole 具有抗菌活性,可用于厌氧菌引起的阑尾炎、盆腔炎等细菌感染研究。
T3263 (6R,7S)-Cefminox sodium heptahydrate

Meicelin,头孢米诺钠,Cefminox Sodium,Alteporina,Tencef

Antibiotic Microbiology/Virology
(6R,7S)-Cefminox sodium heptahydrate (Meicelin) 是一种 Cefminox sodium heptahydrate 的异构体。它也是一种具有广谱抗菌活性的 β-内酰胺头孢菌素抗生素。
T12022 Metronidazole Benzoate

Benzoyl metronidazole

Antibacterial Microbiology/Virology
Metronidazole Benzoate (Benzoyl metronidazole) 是甲硝唑和苯甲酸衍生物,具有抗菌,抗寄生虫,抗滴虫等作用,常用于治疗由厌氧菌引起的感染。
T11427 Antibacterial compound 2

Antifungal Microbiology/Virology
Antibacterial compound 2 是一种有效的抗菌剂,对许多人类兽医病原体有效,对多重耐药葡萄球菌、肠球菌和链球菌,以及厌氧菌有抑制作用。
T7043 Cefotetan

头孢替坦,Apacef

Antibacterial; Antibiotic Microbiology/Virology
Cefotetan (Apacef) 是一种半合成的头霉素抗生素,能抑制细胞壁合成发挥杀菌作用。
T0195 Secnidazole

RP-14539,PM-185184,塞克硝唑

Antibiotic; Parasite Microbiology/Virology
Secnidazole (PM-185184) 是一种具有口服活性唑类抗生素,半衰期比甲硝唑更长。它有潜力研究细菌性阴道病。
T31590 E 4441

E-4441,E4441

E 4441 is a third-generation difluoroquinolone, which has good activity against G(+) aerobic bacteria and anaerobic bacteria in vitro and in vivo.
T32949 Luminamicin

Luminamicin is active against anaerobic bacteria, especially Clostridium sp.; isolated from actinomycete strain OMR-59.
T33899 PD 131628

PD131628,PD-131628

PD 131628 is a novel fluoroquinolone that is a bioactive form of PD 131112 or CI-990 for use against anaerobic bacteria.
T3052L Sancycline HCl

6-Demethyl-6-deoxytetracycline,GS-2147,GS2147,GS 2147,NSC 51812 (as hydrochloride),Bonomycin

Sancycline is a semi-synthetic tetracycline antibiotic that is more active than tetracycline against 339 strains of anaerobic bacteria (MIC90s = 1 and 32 μg/ml, respectively).
T9233 Metronidazole acetic acid

Antibacterial; Antibiotic; Parasite Microbiology/Virology
Metronidazole acetic acid 是 Metronidazole 的代谢产物,在细菌中具有诱变活性。Metronidazole 是硝基咪唑类抗生素,杀螨剂和抗原生动物剂。
T21400 Cefotetan disodium

YM09330,YM-09330,ICI-156834,ICI 156834,YM 09330,Cefotetan Sodium,ICI156834

Cefotetan Sodium, a second-generation cephalosporin, cephamycin antibiotic, is active against a wide range of both aerobic and anaerobic gram-negative and gram-positive bacteria. Cefotetan disrupts the cell wall synthesis by binding to penicillin-binding
T40605 N-(2-Hydroxyethyl)oxamic acid

N-(2-hydroxyethyl)-oxamic acid, a compound derived from the reduction of Metronidazole, can result from either chemical processes or through interaction with intestinal bacteria. Metronidazole itself is a nitroimidazole antibiotic with a broad range of efficacy against protozoans, as well as both Gram-negative and Gram-positive anaerobic bacteria.
T38322 A-54556B

A-54556B is a natural acyldepsipeptide (ADEP) antibiotic isolated from the fermentation broth of S. hawaiiensis. Like the closely related ADEP, A-54556A , A-54556B is effective against Gram-positive bacteria, including penicillin-resistant S. aureus. A-54556B is also effective against many strains of anaerobic bacteria.
T6471 Dicloxacillin Sodium

Veracillin,双氯西林,BRL1702 Sodium,BRL1702,Sodium dicloxacillin,双氯西林钠

Others; Antibacterial; Antibiotic Microbiology/Virology; Others
Dicloxacillin Sodium (BRL1702 Sodium) 是一种青霉素类窄谱β内酰胺抗生素, 用于革兰氏阳性菌感染的研究。它对β-内酰胺酶产生的微生物有抗菌作用。
T73902 Desacetylcefotaxime

Desacetylcefotaxime, Cefotaxime的一种体内代谢物,具有类似其母体化合物对多种需氧和厌氧细菌的体外抗菌活性。
T38321 A-39183A

A-39183A is an active component of the A-39183 antibiotic complex produced by aerobic fermentation of Streptomyces NRRL 12049. It has activity against penicillin-resistant S. aureus 3055 and S. faecalis X66 (MICs = 32 and 32 μg/ml, respectively) and a variety of Gram-positive and Gram-negative anaerobic bacteria (MICs = 16-128 μg/ml) in an agar dilution assay.
T34548 SC 28538

SC28538,SC-28538

SC 28538是一种5-硝基咪唑衍生物。它已被证明对脆弱芽孢杆菌、产气荚膜梭菌、阴道滴虫、胎儿滴虫、人型疟原虫和淋病奈瑟菌具有活性。在与284株厌氧菌的比较研究中,SC 28538的活性与甲硝唑或奥硝唑相同。
T75287 Sitafloxacin monohydrate

Sitafloxacin monohydrate (DU6859a) 是一种具有广谱的抗菌活性,并对多种革兰氏阳性和革兰氏阴性细菌(包括厌氧菌)以及非典型病原体有效的口服活性氟喹诺酮类抗生素。它主要用于研究呼吸道感染和尿路感染。
T75286 Sitafloxacin hydrochloride

Sitafloxacin (DU6859a) hydrochloride 是一款有效的口服活性氟喹诺酮类抗生素,它对广泛的革兰氏阳性细菌、革兰氏阴性细菌(包括厌氧菌)及非典型病原体都显示出抗菌活性。该化合物主要用于研究呼吸道感染和尿路感染。
T75308 Secnidazole hemihydrate

Secnidazole (RP-14539) hemihydrate是一种具有口服活性的唑类抗生素及咪唑缓释剂,能够抑制黏质沙雷菌毒力,并类似于酰基高丝氨酸内酯地减缓QS导致的铜绿假单胞菌发病。在体外,Secnidazole hemihydrate对多种厌氧革兰氏阴性和革兰氏阳性细菌显示出抗菌活性。此化合物在阿米巴病、贾第虫病和细菌性阴道炎等疾病研究中有应用潜力。
T65598 Cefminox sodium

Cefminox (Sodium) is a new cephamycin antibiotic possessing a D-amino acid moiety derived from D-cysteine at the C-7B side chain. Cefminox is active against a wide range of bacteria, especially Gram-negative and anaerobic bacteria. Cefminox shows excellent in vivo efficacy (ED50) which is higher than would be expected from its in vitro activity (MIC). Moreover, cefminox possesses more potent activity in suppression of bacterial regrowth than other cephems[1]. Cefminox (Sodium) was the most activ...
T37880 OPC-167832

OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-167832 exhibits very low MICs against laboratory strains of M. tuberculosis H37Rv (MIC: 0.0005 μg/ml) and Kurono (MIC: 0.0005 μg/ml) and strains with monoresistance to rifampin (RIF), isoniazid (INH), ethambutol (EMB), streptomycin (STR), and pyrazinamide (PZA) (MIC: 0.00024-0.001 ...

化合物

Tinidazole
Cat.No: T0893
Synonym: 替硝唑,CP12574
Target: Antibacterial, Antibiotic
Balofloxacin
Cat.No: T0116
Synonym:
Target: DNA gyrase, Antibacterial, Antibiotic
Tizoxanide
Cat.No: T2279
Synonym: 替唑尼特,Desacetyl-nitazoxanide,TIZ
Target: Antiviral, HIV Protease, Antibacterial, Autophagy
Ertapenem sodium
Cat.No: T4991
Synonym: 厄他培南钠,MK-826,L-749345,尔他培南钠
Target: Antibacterial, Antibiotic
Clinafloxacin
Cat.No: T1283
Synonym: 克林沙星,PD 127391,CI-960,AM-1091
Target: Antibacterial, Antibiotic
Ticarcillin sodium
Cat.No: T6706
Synonym: Ticarpen hydrate,Aerugipen hydrate,替卡西林单钠盐单水合物,BRL 2288,AB 2288,Monapen
Target: Others, Antibacterial, Antibiotic
Morinidazole
Cat.No: T12096L
Synonym:
Target: Antibacterial
(6R,7S)-Cefminox sodium heptahydrate
Cat.No: T3263
Synonym: Meicelin,头孢米诺钠,Cefminox Sodium,Alteporina,Tencef
Target: Antibiotic
Metronidazole Benzoate
Cat.No: T12022
Synonym: Benzoyl metronidazole
Target: Antibacterial
Antibacterial compound 2
Cat.No: T11427
Synonym:
Target: Antifungal
Cefotetan
Cat.No: T7043
Synonym: 头孢替坦,Apacef
Target: Antibacterial, Antibiotic
Secnidazole
Cat.No: T0195
Synonym: RP-14539,PM-185184,塞克硝唑
Target: Antibiotic, Parasite
E 4441
Cat.No: T31590
Synonym: E-4441,E4441
Target:
Luminamicin
Cat.No: T32949
Synonym:
Target:
PD 131628
Cat.No: T33899
Synonym: PD131628,PD-131628
Target:
Sancycline HCl
Cat.No: T3052L
Synonym: 6-Demethyl-6-deoxytetracycline,GS-2147,GS2147,GS 2147,NSC 51812 (as hydrochloride),Bonomycin
Target:
Metronidazole acetic acid
Cat.No: T9233
Synonym:
Target: Antibacterial, Antibiotic, Parasite
Cefotetan disodium
Cat.No: T21400
Synonym: YM09330,YM-09330,ICI-156834,ICI 156834,YM 09330,Cefotetan Sodium,ICI156834
Target:
N-(2-Hydroxyethyl)oxamic acid
Cat.No: T40605
Synonym:
Target:
A-54556B
Cat.No: T38322
Synonym:
Target:
Dicloxacillin Sodium
Cat.No: T6471
Synonym: Veracillin,双氯西林,BRL1702 Sodium,BRL1702,Sodium dicloxacillin,双氯西林钠
Target: Others, Antibacterial, Antibiotic
Desacetylcefotaxime
Cat.No: T73902
Synonym:
Target:
A-39183A
Cat.No: T38321
Synonym:
Target:
SC 28538
Cat.No: T34548
Synonym: SC28538,SC-28538
Target:
Sitafloxacin monohydrate
Cat.No: T75287
Synonym:
Target:
Sitafloxacin hydrochloride
Cat.No: T75286
Synonym:
Target:
Secnidazole hemihydrate
Cat.No: T75308
Synonym:
Target:
Cefminox sodium
Cat.No: T65598
Synonym:
Target:
OPC-167832
Cat.No: T37880
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3982 Vulpinic Acid

狐衣酸,Vulpic acid,Pulvinic acid methyl ester

Others Others
Vulpinic Acid (Pulvinic acid methyl ester) 是地衣代谢物,可降低人脐静脉内皮细胞 (HUVEC) 中 H2O2诱导的ROS,氧化应激和氧化应激相关损伤,可作用于厌氧菌、葡萄球菌及肠球菌。它对脉粥样硬化的研究具有潜在的价值。
T8302 Ceftiofur

Antibacterial; Antibiotic Microbiology/Virology
Ceftiofur 是一种半合成抗生素,对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。
T20643 Cefoxitin

Rephoxitin,Cefoxitinum

Cell wall; Antibacterial; Antibiotic Immunology/Inflammation; Microbiology/Virology
Cefoxitin (Rephoxitin) 是一种广谱的、可口服的第二代头孢霉素类抗生素。Cefoxitin 干扰细菌细胞壁的合成。其活性谱包括革兰氏阴性和革兰氏阳性菌,通常用于腹腔感染、盆腔感染和某些类型的妇科感染等腹部,对厌氧菌具有高效性。
T1277 Lincomycin hydrochloride

Lincomycin HCl,NSC 70731,盐酸林可霉素,U10149A

ribosome; Antibacterial; Antibiotic Microbiology/Virology
Lincomycin hydrochloride (U10149A) 是由林可链霉菌产生的抗生素,对革兰氏阳性球菌和厌氧菌具有活性。

天然产物

Vulpinic Acid
Cat.No: T3982
Synonym: 狐衣酸,Vulpic acid,Pulvinic acid methyl ester
Target: Others
Ceftiofur
Cat.No: T8302
Synonym:
Target: Antibacterial, Antibiotic
Cefoxitin
Cat.No: T20643
Synonym: Rephoxitin,Cefoxitinum
Target: Cell wall, Antibacterial, Antibiotic
Lincomycin hydrochloride
Cat.No: T1277
Synonym: Lincomycin HCl,NSC 70731,盐酸林可霉素,U10149A
Target: ribosome, Antibacterial, Antibiotic
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