Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dicloxacillin Sodium (BRL1702 Sodium) 是一种青霉素类窄谱β内酰胺抗生素, 用于革兰氏阳性菌感染的研究。它对β-内酰胺酶产生的微生物有抗菌作用。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 432 | 待询 | ||
50 mg | ¥ 640 | 待询 | ||
100 mg | ¥ 1,152 | 待询 | ||
200 mg | ¥ 2,074 | 待询 | ||
1 mL * 10 mM (in DMSO) | ¥ 848 | 待询 |
Dicloxacillin Sodium 的其他形式现货产品:
产品描述 | Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria. |
体外活性 | Dicloxacillin Sodium is a narrow-spectrum β-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible Gram-positive bacteria. It is active against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins.[1] Like other β-lactam antibiotics, dicloxacillin acts by inhibiting the synthesis of bacterial cell walls. It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall of Gram-positive bacteria. Dicloxacillin is insensitive to beta-lactamase (also known as penicillinase) enzymes secreted by many penicillin-resistant bacteria. The presence of the isoxazolyl group on the side-chain of the penicillin nucleus facilitates the β-lactamase resistance, since they are relatively intolerant of side-chain steric hindrance. Thus, it is able to bind to penicillin-binding proteins (PBPs) and inhibit peptidoglycan crosslinking, but is not bound by or inactivated by β-lactamases. [2] |
别名 | Veracillin, 双氯西林, BRL1702 Sodium, BRL1702, Sodium dicloxacillin, 双氯西林钠 |
分子量 | 510.32 |
分子式 | C19H17Cl2N3O5S·H2O·Na |
CAS No. | 343-55-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 93 mg/mL (182.2 mM)
H2O: 92 mg/mL (180.3 mM)
Ethanol: 21 mg/mL (41.2 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO / H2O / Ethanol | 1 mM | 1.9596 mL | 9.7978 mL | 19.5955 mL | 48.9889 mL |
5 mM | 0.3919 mL | 1.9596 mL | 3.9191 mL | 9.7978 mL | |
10 mM | 0.196 mL | 0.9798 mL | 1.9596 mL | 4.8989 mL | |
20 mM | 0.098 mL | 0.4899 mL | 0.9798 mL | 2.4494 mL | |
DMSO / H2O | 50 mM | 0.0392 mL | 0.196 mL | 0.3919 mL | 0.9798 mL |
100 mM | 0.0196 mL | 0.098 mL | 0.196 mL | 0.4899 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Dicloxacillin Sodium 343-55-5 Microbiology/Virology Others Antibacterial Antibiotic Veracillin 双氯西林 Bacterial penicillin BRL1702 Sodium BRL1702 Sodium dicloxacillin Dicloxacillin 双氯西林钠 β-lactam antibiotic inhibit Inhibitor BRL 1702 BRL-1702 inhibitor