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Cat. No.	Product Name	Target	Signaling Pathways
T14983	Clomethiazole Distraneurin,Chlormethiazole,氯美噻唑,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE	P450; GABA Receptor	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Clomethiazole (Distraneurin) 是口服GABAA 激动剂，可抑制人肝微粒体中的细胞色素 P450 异构体，CYP2A6 和 CYP2E1。它有抗惊厥作用，具有治疗惊厥性癫痫持续状态的潜力。
T25813	Milenperone R 34009,R-34009,R34009	Others	Others
	Milenperone (R 34009) 是一种新型抗侵袭化合物，可用于控制癫痫和酗酒患者行为障碍。
T0963	Naltrexone hydrochloride Depade,盐酸纳曲酮,Trexan,Naltrexone HCl,Antaxone	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Naltrexone hydrochloride (Naltrexone HCl) 是一种合成的 opiate 拮抗剂，用于预防 opiate 成瘾和酗酒的复发。
T28888	Surinabant SR 147778,SR147778,SR-147778
	Surinabant, a cannabinoid CB1 antagonist, is used potentially for the treatment of obesity and alcoholism.
T73059	Acamprosate
	Acamprosate 是一种口服活性原型神经调节剂。Acamprosate 可用于酒精依赖和酒精中毒的研究。
T27939	LY2940094 tartrate LY2940094,LY 2940094,LY-2940094 tartrate,LY-2940094
	LY-2940094, a nociceptin receptor antagonist, is used potentially for the treatment of major depressive disorder and alcoholism.
T13652	Dicarbine	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Double carbene can be used for the study of schizophrenia and alcoholism. It can block dopamine receptors in various parts of the brain and prevent the reduction of conditioned defense reflexes caused by the stimulation of the mid-brain part of the networ
T26569	ADX71441 ADX 71441,ADX-71441
	ADX71441 is a GABAB positive allosteric modulator (PAM). ADX71441 increases urinary latencies and reduces the number of urinary events and the total and average urinary volumes. ADX71441 may also mitigate alcoholism and have analgesic effects in the bladd
T2092L	Amitifadine free base DOV 21947,DOV-21947,DOV21,947,DOV21947,DOV 21,947,DOV-21,947
	Amitifadine(DOV-21947, EB-1010) is an inhibitor of the so-called triple reuptake or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) and is an antidepressant drug candidate. Amitifadine reduces binge drinking and negative affect in an animal m
T36947	Pyrithiamine (hydrobromide)
	Pyrithiamine is the pyridine analog of thiamine that prevents growth of organisms that require intact thiamine. [1] It inhibits the growth of bacterial and fungal species at a pyrithiamine:thiamine ratio of 10:1 in growth media and induces symptoms of thiamine deficiency in mice at a dietary ratio of 3:1. These effects are reversible with addition of sufficient thiamine in all species. Pyrithiamine inhibits the formation of cocarboxylase from thiamine in chicken blood in a dose-dependent manner....
T79806	5-HT2A&5-HT2C agonist-1	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT2A&5-HT2C agonist-1 (Example 2) 是一种选择性的5-HT2A和5-HT2C受体激动剂，其IC50值分别为196 nM和0.9 nM。本化合物主要应用于研究抑郁症、酒精依赖、烟草和可卡因成瘾、炎症、丛集性头痛、PTSD、癫痫等中枢神经系统相关疾病。
T79805	5-HT2 agonist-1 free base	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT2 agonist-1 (Compound 24) free base 是一种作用于5-HT2A, 5-HT2B和5-HT2C受体的激动剂，其IC50值分别为10 nM, 8.3 nM和1.6 nM。该化合物主要应用于研究抑郁症、酒精依赖、烟草及可卡因成瘾、炎症、丛集性头痛、创伤后应激障碍(PTSD)、癫痫以及其他中枢神经系统相关疾病。
T79804	5-HT2 agonist-1	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT2 agonist-1 (Compound 24) 是一种选择性5-HT2A, 5-HT2B和5-HT2C激动剂，其IC50值分别为10 nM, 8.3 nM和1.6 nM。5-HT2 agonist-1 free base主要用于研究治疗抑郁症、酗酒、吸烟与可卡因依赖、炎症、丛集性头痛、创伤后应激障碍(PTSD)、癫痫以及其他中枢神经系统疾病。

化合物

Cat.No: T14983

Synonym: Distraneurin,Chlormethiazole,氯美噻唑,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE

Target: P450, GABA Receptor

Cat.No: T25813

Synonym: R 34009,R-34009,R34009

Target: Others

Naltrexone hydrochloride

Cat.No: T0963

Synonym: Depade,盐酸纳曲酮,Trexan,Naltrexone HCl,Antaxone

Target: Opioid Receptor

Cat.No: T28888

Synonym: SR 147778,SR147778,SR-147778

Cat.No: T73059

LY2940094 tartrate

Cat.No: T27939

Synonym: LY2940094,LY 2940094,LY-2940094 tartrate,LY-2940094

Cat.No: T13652

Target: Dopamine Receptor

Cat.No: T26569

Synonym: ADX 71441,ADX-71441

Amitifadine free base

Cat.No: T2092L

Synonym: DOV 21947,DOV-21947,DOV21,947,DOV21947,DOV 21,947,DOV-21,947

Pyrithiamine (hydrobromide)

Cat.No: T36947

5-HT2A&5-HT2C agonist-1

Cat.No: T79806

Target: 5-HT Receptor

5-HT2 agonist-1 free base

Cat.No: T79805

Target: 5-HT Receptor

5-HT2 agonist-1

Cat.No: T79804

Target: 5-HT Receptor

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