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Search Results for " tsa "

Targets Recommended: Apoptosis HDAC Autophagy

8

抑制剂 & 化合物

2

天然产物

13

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6161	Tubastatin A Hydrochloride TSA HCl,Tubastatin A HCl	Apoptosis; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Tubastatin A Hydrochloride (TSA HCl) 是一种选择性的 HDAC6抑制剂，IC50值为 15 nM，对其选择性是 HDAC8 外的其他亚型的 1000 多倍。
T6112	Doxercalciferol TSA 840,度骨化醇,Hectorol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2	Others	Others
	Doxercalciferol (TSA 840) 是一种维生素 D2 类似物，是一种维生素 D 受体激活剂，能够阻碍肾病的进程。
T19209	Biotinyl tyramide 生物素基酪氨酰胺,维生素苯酚	Others	Others
	Biotinyl tyramide 是一种能够用于酪胺信号放大的生物素衍生物，可用于免疫组织化学信号放大和原位杂交实验。
T3358	ITSA-1 ITSA1	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	ITSA-1 是一种具有膜渗透性的HDAC 激活剂，抵消曲古抑菌素 A (TSA) 诱导的细胞周期停滞，组蛋白乙酰化和转录水平。
T5104	BTSA1	Apoptosis; BCL	Apoptosis
	BTSA1 是一种有口服活性的 BAX 激活剂，IC50为 250 nM，EC50为 144 nM。它以高亲和力和特异性与 N 末端激活位点结合，并诱导 BAX 发生构象变化，从而导致BAX 介导的细胞凋亡。
T76067	Dabcyl-KTSAVLQSGFRKME-Edans TFA
	Dabcyl-KTSAVLQSGFRKME-Edans TFA 是一种用于测量蛋白酶酶促活性的荧光肽，具有研究2019-nCoV (COVID-19) 感染潜力的特性。该化合物作为底物，用于相关蛋白酶活性的测定。
T124999	Tsaokoin
	Tsaokoin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124999。
T39546	Fluorescein tyramide
	Fluorescein tyramide is a widely utilized green fluorescent reagent (λ abs : 494 nm; λ em : 517 nm), primarily employed for tyramide signal amplification (TSA) in low-abundance IHC, ICC, in situ hybridization (FISH), and flow cytometry (FCM) applications.

化合物

Tubastatin A Hydrochloride

Cat.No: T6161

Synonym: TSA HCl,Tubastatin A HCl

Target: Apoptosis, HDAC, Autophagy

Doxercalciferol

Cat.No: T6112

Synonym: TSA 840,度骨化醇,Hectorol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2

Target: Others

Biotinyl tyramide

Cat.No: T19209

Synonym: 生物素基酪氨酰胺,维生素苯酚

Target: Others

Cat.No: T3358

Synonym: ITSA1

Target: HDAC

Cat.No: T5104

Target: Apoptosis, BCL

Dabcyl-KTSAVLQSGFRKME-Edans TFA

Cat.No: T76067

Cat.No: T124999

Fluorescein tyramide

Cat.No: T39546

Cat. No.	Product Name	Target	Signaling Pathways
T6270	Trichostatin A 曲古柳菌素A,曲古抑菌素A,TSA	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Trichostatin A (TSA) 属于二烯异羟肟酸类的天然衍生物。Trichostatin A 是一种组蛋白去乙酰化酶抑制剂 (IC50=1.8 nM)，具有可逆性和特异性。Trichostatin A 导致核心组蛋白过度乙酰化，从而调节染色质结构。
TN6363	Tsaokoarylone
	Tsaokoarylone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6363，CAS号为 811471-20-2。

天然产物

Cat.No: T6270

Synonym: 曲古柳菌素A,曲古抑菌素A,TSA

Target: HDAC

Tsaokoarylone

Cat.No: TN6363

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05169	Peroxiredoxin 2 Protein, Mouse, Recombinant (His) Torin,TPx-B,Band-8,peroxiredoxin 2,PRP,AL022839,TR,TPx,Tdpx1...	Mouse	Baculovirus Insect Cells
	Peroxiredoxin 2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24.1 kDa and the accession number is Q61171.
TMPY-02200	Peroxiredoxin 2 Protein, Human, Recombinant (His) PRP,HEL-S-2a,TSA,NKEF-B,TDPX1,PTX1,TPX1,peroxiredox...	Human	Baculovirus Insect Cells
	Peroxiredoxin 2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P32119.
TMPY-02307	B7-1 Protein, Mouse, Recombinant (His) TSA1,Ly-53,Cd28l,MIC17,Ly53,B71,CD80 molecule	Mouse	HEK293 Cells
	B7-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.1 kDa and the accession number is Q00609-1.
TMPY-06711	B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated MIC17,Ly-53,Cd28l,B71,Ly53,TSA1,CD80 molecule	Mouse	HEK293 Cells
	B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 26.94 kDa and the accession number is Q00609-1.
TMPY-02363	B7-1 Protein, Mouse, Recombinant (hFc) Ly-53,CD80 molecule,MIC17,B71,Cd28l,Ly53,TSA1	Mouse	HEK293 Cells
	B7-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.7 kDa and the accession number is Q00609-1.
TMPY-05811	B7-1 Protein, Mouse, Recombinant (His), Biotinylated B71,Cd28l,Ly-53,MIC17,Ly53,CD80 molecule,TSA1	Mouse	HEK293 Cells
	B7-1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.1 kDa and the accession number is Q00609-1.
TMPY-01841	Serpin I2 Protein, Human, Recombinant (His) PI14,TSA2004,PANCPIN,MEPI,Serpin I2,serpin peptidas...	Human	HEK293 Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chy...
TMPH-00745	TsaE Protein, E. coli, Recombinant	E. coli	E. coli
	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro.
TMPY-03283	HBP1 Protein, Human, Recombinant (GST) HMG-box transcription factor 1	Human	E. coli
	HBP1 is a sequence-specific DNA-binding transcription factor. It is involved in many biological processes. It was reported that HBP1 binds to p16(INK4A) promoter and activates p16(INK4A) expression. We found that trichostatin A (TSA), an inhibitor of HDAC (histone deacetylase), induces p16(INK4A) expression in an HBP1-dependent manner. HBP1 activates or represses the expression of some specific genes during cell growth and differentiation. HBP1 was acetylated by p3/CBP in two regions: repression...
TMPJ-00934	PRDX3 Protein, Human, Recombinant Protein MER5 homolog,Thioredoxin-Dependent Peroxide Reductas...	Human	E. coli
	Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with M...
TMPJ-01098	PRDX4 Protein, Human, Recombinant (His) Prx-IV,Thioredoxin-Dependent Peroxide Reductase A0372,PRDX4,...	Human	E. coli
	Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-...
TMPJ-00933	PRDX5 Protein, Human, Recombinant (His) Antioxidant enzyme B166,Alu corepressor 1,Peroxiredoxin-5,PL...	Human	HEK293 Cells
	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/a...
TMPY-00641	LEC/CCL16 Protein, Human, Recombinant (His) SCYL4,HCC-4,ILINCK,LMC,SCYA16,NCC-4,CKb12,Mtn-1,LCC-1,LEC,ch...	Human	E. coli
	CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is a functional ligand for CCR1, CCR2, CCR5, and CCR8. Recombinant CCL16 demonstrated chemotactic activity on human monocytes and lymphocytes. Based on the ability of human chemokines to exert activity on and bind to murine receptors, the TSA mouse adenocarcinoma cell line was trans...

重组蛋白

Peroxiredoxin 2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05169

Species: Mouse

Expression System: Baculovirus Insect Cells

Peroxiredoxin 2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02200

Species: Human

Expression System: Baculovirus Insect Cells

B7-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02307

Species: Mouse

Expression System: HEK293 Cells

B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06711

Species: Mouse

Expression System: HEK293 Cells

B7-1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02363

Species: Mouse

Expression System: HEK293 Cells

B7-1 Protein, Mouse, Recombinant (His), Biotinylated

Cat.No: TMPY-05811

Species: Mouse

Expression System: HEK293 Cells

Serpin I2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01841

Species: Human

Expression System: HEK293 Cells

TsaE Protein, E. coli, Recombinant

Cat.No: TMPH-00745

Species: E. coli

Expression System: E. coli

HBP1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-03283

Species: Human

Expression System: E. coli

PRDX3 Protein, Human, Recombinant

Cat.No: TMPJ-00934

Species: Human

Expression System: E. coli

PRDX4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01098

Species: Human

Expression System: E. coli

PRDX5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00933

Species: Human

Expression System: HEK293 Cells

LEC/CCL16 Protein, Human, Recombinant (His)

Cat.No: TMPY-00641

Species: Human

Expression System: E. coli

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