首页工具

登录

搜索结果

Search Results for " trailr2 "

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

Targets Recommended: TNF

2

抑制剂 & 化合物

12

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T76787	Conatumumab TRAIL-R2 mAb,AMG 655	TNF	Apoptosis
	Conatumumab (AMG 655) 是一种靶向人死亡受体 5 (DR5，TRAILR2) 的单克隆激动剂抗体，对长型 DR5 的 Kd 为 1 nM, 对短型 DR5 的 Kd 0.8 nM。Conatumumab 通过半胱天冬酶激活在多种肿瘤类型中诱导细胞凋亡。Conatumumab 可用于研究晚期实体肿瘤。
T77876	Py-MAA-Val-Cit-PAB-MMAE AAJ8D6-PY-Val-Cit-MMAE
	Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) 是一款ADC Linker，专用于合成抗体药物偶联物Zapadcine-3a (ADC)。Zapadcine-3a 对抗多种肿瘤表现出高效的活性，其作用机理为定位TRAILR2并通过肿瘤细胞内的溶酶体被摄取，进而针对性释放致死的小分子，从而特异性消灭TRAILR2阳性的肿瘤细胞，并能够有效地治愈肿瘤。

化合物

Cat.No: T76787

Synonym: TRAIL-R2 mAb,AMG 655

Target: TNF

Py-MAA-Val-Cit-PAB-MMAE

Cat.No: T77876

Synonym: AAJ8D6-PY-Val-Cit-MMAE

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01185	DR5/TRAIL R2 Protein, Human, Recombinant (His) KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor nec...	Human	HEK293 Cells
	DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-01437	DR5/TRAIL R2 Protein, Mouse, Recombinant (His) TRAILR2,MK,TRICKB,TRICK2B,TRICK	Mouse	HEK293 Cells
	DR5/TRAIL R2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is Q9QZM4.
TMPY-01452	DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) TRICK2B,DR5,tumor necrosis factor receptor superfam...	Mouse	HEK293 Cells
	DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 41.8 kDa and the accession number is Q9QZM4.
TMPY-05388	DR5/TRAIL R2 Protein, Human, Recombinant (hFc) tumor necrosis factor receptor superfamily, member 10b,T...	Human	HEK293 Cells
	DR5/TRAIL R2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is AAB67103.1.
TMPY-06835	DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated TRICK2A,DR5,tumor necrosis factor receptor superfam...	Human	HEK293 Cells
	DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.54 kDa and the accession number is NP_003833.4.
TMPK-00277	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc) TRAIL R2,TNFRSF10B,TRICK2,KILLER,DR5,TRAIL...	Human	HEK293 Cells
	DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
TMPK-00276	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi) ZTNFR9,DR5TRICK2B,DR5,TRAIL receptor 2,TRI...	Human	HEK293 Cells
	DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
TMPY-05477	DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated DR5,tumor necrosis factor receptor superfamily, member 10b,T...	Human	HEK293 Cells
	DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.8 kDa and the accession number is O14763-1.
TMPJ-00275	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated DR5,Tumor Necrosis Factor Receptor Superfamily Member 10B,TR...	Human	HEK293 Cells
	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 18-25 KDa and the accession number is O14763.
TMPJ-00430	TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His) Death Receptor 5,TRAILR2,CD26...	Cynomolgus	HEK293 Cells
	TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 22-30 KDa and the accession number is A0A2K5TXK0.
TMPJ-00276	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His) DR5,TRAILR2,TRICK2,TNFRSF10B,KILL...	Human	HEK293 Cells
	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 49 KDa and the accession number is O14763.
TMPK-00708	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc) TRAIL R1,APO2,DR4,CD261,TRAIL-R,TNFRSF10A,...	Human	HEK293 Cells
	Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations.

重组蛋白

DR5/TRAIL R2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01185

Species: Human

Expression System: HEK293 Cells

DR5/TRAIL R2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01437

Species: Mouse

Expression System: HEK293 Cells

DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01452

Species: Mouse

Expression System: HEK293 Cells

DR5/TRAIL R2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05388

Species: Human

Expression System: HEK293 Cells

DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06835

Species: Human

Expression System: HEK293 Cells

TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00277

Species: Human

Expression System: HEK293 Cells

TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00276

Species: Human

Expression System: HEK293 Cells

DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05477

Species: Human

Expression System: HEK293 Cells

TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00275

Species: Human

Expression System: HEK293 Cells

TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00430

Species: Cynomolgus

Expression System: HEK293 Cells

TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00276

Species: Human

Expression System: HEK293 Cells

TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00708

Species: Human

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼