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Cat. No. Product Name Target Signaling Pathways
T125567 AAL Toxin TC1

AAL Toxin TC1 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125567。
T23423 TC 1

Others Others
σ1 receptor ligand
T9083 TC11

CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11

BCL; Caspase; CDK Apoptosis; Cell Cycle/Checkpoint; Proteases/Proteasome
TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) 是一种有效的肿瘤细胞增殖抑制剂,并通过激活 caspase-3、8 和 9 诱导细胞凋亡。在长时间有丝分裂阻滞期间,它诱导 MCL1降解导致凋亡。它作为苯酞酰亚胺衍生物在结构上与免疫调节药物相关。
TP2112L TC14012 acetate

TC14012 acetate(368874-34-4 free base)

CXCR; Arrestin Autophagy; GPCR/G Protein; Immunology/Inflammation
TC14012 acetate 是 T140 的血清稳定衍生物,是一种选择性的肽模拟 CXCR4 拮抗剂,IC50 为 19.3 nM。 TC14012 还是一种有效的 CXCR7 激动剂,EC50 为 350 nM,可将 β-arrestin 2 募集到 CXCR7。 TC14012 具有抗癌活性和抗 HIV 活性。
T61531 NFATc1-IN-1

RANKL/RANK NF-κB
NFATc1-IN-1 (also known as compound A04) is a highly effective inhibitor of osteoclast formation induced by RANKL, with an IC50 of 1.57 μM. It exerts its anti-osteoclastogenic effects by attenuating the RANKL-induced nuclear translocation of NFATc1. Due to its remarkable properties, NFATc1-IN-1 holds significant potential for advancing research related to osteoclastic diseases [1].
T34425 RTC13

Read-through compound 13,RTC 13,RTC-13

RTC13, as a premature termination codon (PTC) readthrough inducer, can act by restoring dystrophin expression and improving muscle function in the mdx mouse model for Duchenne muscular dystrophy.
T74400 TC113

TC113是一种与c(RGDyK)偶联的Gemcitabine。它通过整合素αvβ3可被A549细胞内化。此外,TC113对WM266.4和A549细胞表现出显著的抗增殖效果。
TP2112 TC14012

TC 14012

CXCR4 antagonist and ACKR3 (CXCR7) agonist (EC50 = 350 nM for CXCR7).
T75801 TC14012 TFA

TC14012 TFA 是 T140 的血清稳定衍生物,是一种选择性的 CXCR4拮抗剂,IC50为 19.3 nM。TC14012 TFA 是有效的 CXCR7激动剂,可将 β-arrestin2 募集到 CXCR7,EC50为 350 nM。TC14012 TFA 具有抗 HIV 活性和抗癌活性。
T34426 RTC14

Read-through compound-14,RTC 14,RTC-14,Read-through compound 14

RTC14, as a premature termination codon (PTC) readthrough inducer, can act by restoring dystrophin expression and improving muscle function in the mdx mouse model for Duchenne muscular dystrophy.
T17010 TC13172

Others Others
TC13172 is an inhibitor of mixed lineage kinase domain-like protein (EC50: 2 nM for HT-29 cells).

化合物

AAL Toxin TC1
Cat.No: T125567
Synonym:
Target:
TC 1
Cat.No: T23423
Synonym:
Target: Others
TC11
Cat.No: T9083
Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11
Target: BCL, Caspase, CDK
TC14012 acetate
Cat.No: TP2112L
Synonym: TC14012 acetate(368874-34-4 free base)
Target: CXCR, Arrestin
NFATc1-IN-1
Cat.No: T61531
Synonym:
Target: RANKL/RANK
RTC13
Cat.No: T34425
Synonym: Read-through compound 13,RTC 13,RTC-13
Target:
TC113
Cat.No: T74400
Synonym:
Target:
TC14012
Cat.No: TP2112
Synonym: TC 14012
Target:
TC14012 TFA
Cat.No: T75801
Synonym:
Target:
RTC14
Cat.No: T34426
Synonym: Read-through compound-14,RTC 14,RTC-14,Read-through compound 14
Target:
TC13172
Cat.No: T17010
Synonym:
Target: Others
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