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Cat. No. Product Name Target Signaling Pathways
T0188 Fluticasone (propionate)

丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate

Glucocorticoid Receptor; Virus Protease; Estrogen/progestogen Receptor; Phospholipase; Endogenous Metabolite Endocrinology/Hormones; Metabolism; Microbiology/Virology
Fluticasone propionate (CCI-187881) 是一种选择性糖皮质激素受体激动剂,是一种局部抗炎激素,亲和力KD 为 0.5 nM。具有抗病毒活性。
T0089 Cetirizine dihydrochloride

盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Cetirizine dihydrochloride (UCB P071) 是羟嗪的羧化代谢物,是特异性口服有效的 H1 受体长效拮抗剂。它标记抗过敏特性,抑制过敏反应期间嗜酸性粒细胞趋化,可有效治疗过敏性鼻炎、确诊荨麻疹和花粉诱发的哮喘。
T1278 Astemizole

Laridal,Histaminos,Paralergin,阿司咪唑

Potassium Channel; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
Astemizole (Laridal) 是一种长效、非镇静抗组胺药,用于治疗季节性过敏性鼻炎、哮喘、过敏性结膜炎和慢性特发性荨麻疹。它是组胺 H1 受体的拮抗剂,IC50值为 4 nM,还阻断 hERG K+通道,IC50值为 0.9 nM,具有抗胆碱能和止痒作用。
T0118 Mizolastine

SL 850324,咪唑司汀,咪唑斯汀

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Mizolastine (SL 850324) 是组胺 H1 受体拮抗剂,IC50为 47 nM。它用于治疗过敏反应,如花粉热和荨麻疹等。
T60951 Molnupiravir

EIDD-2801,Lagevrio,MK-4482

SARS-CoV; Influenza Virus Microbiology/Virology
Molnupiravir (MK-4482) (EIDD-2801) 是核糖核苷类似物 EIDD-1931 的异丙酯前体药物,具有口服生物利用度。Molnupiravir 可用于 COVID-19 ,季节性和流行性流感的研究,对多种冠状病毒和流感病毒具有广谱的抗病毒活性,例如,SARS-CoV-2,MERS-CoV,SARS-CoV。
T69501 Montelukast alcohol

Montelukast alcohol is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
T71369 Montelukast sulfoxide

Montelukast sulfoxide is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
T68496 Montelukast cyclopropaneacetamide

Montelukast cyclopropaneacetamide is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
T68295 Montelukast methyl ketone

Montelukast methyl ketone is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
T68348 Montelukast methylstyrene

Montelukast methylstyrene is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
T71152 Montelukast bis-sulfide

Montelukast bis-sulfide is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
T73972 Fexofenadine Impurity F

Fexofenadine Impurity F 是 Fexofenadine 的杂质。 Fexofenadine 是一种H1R 拮抗剂,可用于研究季节性过敏性鼻炎和慢性特发性荨麻疹。
T70904 Tylogenin

Tylogenin, a steroidal aglycone generated by acid hydrolysis from two seasonal glycosides occurring in Tylophora sylvatica, inhibits IgE-induced basophil mediator release for allergic reactions. In the rabbit basophil-dependent serotonin release (BDSR) assay system, the inhibitory activity of tylogenin was significantly greater than that of its parent glycosides, tylophoroside and acetyltylophoroside, and that of dexamethasone. The activity of tylogenin was found to increase with the incubation ...
T79056 Orexin receptor modulator-1

Orexin receptormodulator-1 是一款针对食欲素受体的调节剂,主要应用于物质成瘾、惊恐障碍、焦虑、创伤后应激障碍 (PTSD)、疼痛、抑郁、季节性情感障碍、进食障碍及高血压的科研领域。

化合物

Fluticasone (propionate)
Cat.No: T0188
Synonym: 丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate
Target: Glucocorticoid Receptor, Virus Protease, Estrogen/progestogen Receptor, Phospholipase, Endogenous Metabolite
Cetirizine dihydrochloride
Cat.No: T0089
Synonym: 盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl
Target: Histamine Receptor
Astemizole
Cat.No: T1278
Synonym: Laridal,Histaminos,Paralergin,阿司咪唑
Target: Potassium Channel, Histamine Receptor
Mizolastine
Cat.No: T0118
Synonym: SL 850324,咪唑司汀,咪唑斯汀
Target: Histamine Receptor
Molnupiravir
Cat.No: T60951
Synonym: EIDD-2801,Lagevrio,MK-4482
Target: SARS-CoV, Influenza Virus
Montelukast alcohol
Cat.No: T69501
Synonym:
Target:
Montelukast sulfoxide
Cat.No: T71369
Synonym:
Target:
Montelukast cyclopropaneacetamide
Cat.No: T68496
Synonym:
Target:
Montelukast methyl ketone
Cat.No: T68295
Synonym:
Target:
Montelukast methylstyrene
Cat.No: T68348
Synonym:
Target:
Montelukast bis-sulfide
Cat.No: T71152
Synonym:
Target:
Fexofenadine Impurity F
Cat.No: T73972
Synonym:
Target:
Tylogenin
Cat.No: T70904
Synonym:
Target:
Orexin receptor modulator-1
Cat.No: T79056
Synonym:
Target:
TargetMol Loading
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