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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T75349 |
CDP-Star
|
||
CDP-Star 是碱性磷酸酶的化学发光底物。CDP-Star 可用于酶联免疫分析。 | |||
T2250 |
DY131
DY 131,GSK 9089,DY-131 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Smo | Endocrinology/Hormones; Stem Cells |
DY131 (DY-131) 是选择性的 ERRγ 和 ERRβ 激动剂,对 ERRα,ERα 和 ERβ 无效。它对Smo 的信号传导具有抑制作用。 | |||
T38410 |
Phosphoramide mustard
|
DNA Alkylation; Drug Metabolite | DNA Damage/DNA Repair; Metabolism |
Phosphoramide mustard 是环磷酰胺的毒性代谢物物,具有抗癌活性且对卵巢具有毒性,可诱导 DNA 损伤。 | |||
T2408 |
Ostarine
MK-2866,GTX-024,Enobosarm |
Androgen Receptor | Endocrinology/Hormones |
Ostarine (MK-2866) 是一种具有合成代谢活性的非甾体药物。选择性雄激素受体调节剂 (SARM) GTx-024 旨在像睾酮一样发挥作用,从而促进和/或维持性欲、生育能力、前列腺生长以及肌肉生长和力量。模仿睾酮的作用,这种药物可以增加瘦体重,从而改善癌症恶病质高代谢状态下的肌肉萎缩。 | |||
T19736 |
Aniline mustard
Mesylerythrol,NSC-18429,N,N-双(2-氯乙基)苯胺,Lymphocin |
Others | Others |
Aniline mustard (Mesylerythrol) 是具有抗肿瘤活性的烷基化芥末。 | |||
T15600 |
Istaroxime
PST2744 |
Others | Others |
Istaroxime is an effective inhibitor of Na+, K+-ATPase (IC50: 0.11 μM). | |||
T69179 |
Imidazole mustard
|
||
Imidazole mustard is an inhibitor of purine nucleoside synthesis. | |||
T36701 | Phosphoramide mustard (cyclohexanamine) | ||
Phosphoramide mustard cyclohexanamine is the major metabolite for Cyclophosphamide , with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA adduct formation in ovarian granulosa cells, induces DNA damage and elicits the ovarian DNA repair response[1][2]. Phosphoramide mustard cyclohexanamine causes cytotoxicity through forming cross-linked DNA adducts which inhibit DNA strand separation during replication[1].Phosphoramide mustard cyclohexanamine destroys rapidly dividing ce... | |||
T76850 | Dostarlimab | ||
Dostarlimab (TSR-042) 是一种人源化抗PD-1单克隆抗体。Dostarlimab 与人PD-1具有高亲和力,并竞争性地抑制其与其配体PD-L1和 PD-L2 的相互作用,IC50s 分别为 1.8 nM 和 1.5 nM。 | |||
T126123 |
Wistariasaponin B2
|
||
Wistariasaponin B2 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126123,CAS号为 126594-46-5。 | |||
T25504 | Histargin | ||
Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis. | |||
T69975 | Istaroxime oxalate | ||
Istaroxime, also known as PST-2744, is a positive inotropic agent that mediates its action through inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase). Na+/K+ ATPase inhibition increases intracellular sodium levels, which reverses the driving force of the sodium/calcium exchanger, inhibiting calcium extrusion and possibly facilitating calcium entry. Additionally, Istaroxime increases intracellular calcium by improving the efficacy by which intracellular calcium triggers sarco... | |||
T37031 |
Quinacrine mustard hydrochloride
Quinacrine mustard HCl |
Autophagy | Autophagy |
Quinacrine mustard hydrochloride 是一种荧光染料,也 是一种多环芳香剂,可作为诱变剂诱导细菌的突变体。Quinacrine mustard hydrochloride 能选择性地与腺嘌呤-胸腺嘧啶(AT)碱基对结合,而不 是与鸟嘌呤-胞嘧啶(GC)碱基对结合,诱导细胞周期停滞在 G2/M 期。Quinacrine mustard (hydrochloride) 已被用于标记移相染色体,以通过自动放射摄影技术进行核型分析。 | |||
T126124 |
Wistariasaponin A
|
||
Wistariasaponin A 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126124,CAS号为 126594-36-3。 | |||
T23753 |
Arctigenin mustard
AgM |
||
Arctigenin mustard is a tumor-growth inhibiting substance. | |||
T15599 |
Istaroxime hydrochloride
PST2744 hydrochloride |
Others | Others |
Istaroxime hydrochloride is an inhibitor of Na+/K+-ATPase (IC50: 0.11 μM). It also is a sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA 2) activator. | |||
T29600 |
Acetylethylcholine mustard
Aech-M |
||
Acetylethylcholine mustard can effect muscarinic receptor-coupled attenuation of cAMP formation for intact GH3 cells. | |||
T74284 | SH379 | ||
SH379为2-甲基嘧啶-稠合三环二萜衍生物,是具有口服活性的有效抗迟发性性腺机能减退剂。它显著促进StAR与3β-HSD等关键睾酮合成相关酶的表达,并通过调节AMPK/mTOR信号通路刺激自噬。 | |||
T72213 |
Efonidipine hydrochloride
NZ-105 hydrochloride |
||
Efonidipine(NZ-105)盐酸盐是T 型和L 型钙离子通道双重阻断剂。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN6986 | Corn starch | ||
Corn starch is a natural product. | |||
T83419 |
1α-Hydroxy-3-deoxypseudoanisatin
|
||
1α-Hydroxy-3-deoxypseudoanisatin (Iso-γ-fagarine) 是倍半萜类化合物,可从八角(Illicium merrillianum)果皮中分离。 | |||
T79975 |
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside
|
HBV | Microbiology/Virology |
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside(化合物1)是一种具有抗HBV活性的木脂素类化合物。该化合物对HBV表面抗原(HBsAg)的IC50为0.58 mM,而对HBV e抗原(HBeAg)的IC50 > 2.4 mM。其可从八角茴香中提取分离。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06516 |
GUCY2C Protein, Human, Recombinant (His)
DIAR6,MUCIL,STAR,MECIL,GUC2C |
Human | HEK293 Cells |
GUCY2C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.78 kDa and the accession number is P25092-1. | |||
TMPK-00990 |
GUCY2C Protein, Mouse, Recombinant (His & Avi)
GC-C,STAR,DIAR6,GCC,GUC2CEC 4.6.1.2,STA receptor,MU... |
Mouse | HEK293 Cells |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.01 kDa and the accession number is Q3UWA6-1. | |||
TMPJ-00910 |
GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated
Intestinal guanylate cyclase,STAR,STA receptor,h |
Human | HEK293 Cells |
GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 65-110 KDa and the accession number is P25092. | |||
TMPK-00991 |
GUCY2C Protein, Mouse, Recombinant (His & Avi), Biotinylated
EC 4.6.1,Guanylyl cyclase C,MUCIL,GUC2CEC 4.6.1.2,GUC2C,STA ... |
Mouse | HEK293 Cells |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.01 kDa and the accession number is Q3UWA6-1. | |||
TMPK-01388 |
GUCY2C Protein, Canine, Recombinant (aa 21-430, His)
GC-C,GUCY2C,STAR,EC 4.6.1,STA receptor,GCC,MUCIL,Gu... |
Canine | HEK293 Cells |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Canine, Recombinant (aa 21-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.6 kDa and the accession number is F1PAG3. | |||
TMPK-00856 |
GUCY2C Protein, Human, Recombinant (His & Avi)
GCC,STAR,STA receptor,Guanylyl cyclase C,EC 4.6.1,G... |
Human | HEK293 Cells |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 48.8 kDa and the accession number is P25092-1. | |||
TMPK-01279 |
GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His)
GUC2CEC 4.6.1.2,GCC,Guanylyl cyclase C,STA receptor,MUCIL,GU... |
Cynomolgus | HEK293 Cells |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.2 kDa and the accession number is XP_005570270.1. | |||
TMPJ-00911 |
GUCY2C Protein, Human, Recombinant (hFc)
GUC2C,STAR,hSTAR,GC-C,STA receptor,GUCY2C,... |
Human | HEK293 Cells |
GUCY2C Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P25092. | |||
TMPH-00246 |
Bovine coronavirus (strain Mebus) Non-structural Protein 4a (His & SUMOstar)
ns4.9,4.9 kDa accessory protein,Non-structural protein of 4.... |
BCoV | P. pastoris (Yeast) |
Bovine coronavirus (strain Mebus) Non-structural Protein 4a (His & SUMOstar) is expressed in Yeast. | |||
TMPH-03104 |
CDH3/Cadherin 3 Protein, Pig, Recombinant (His & SUMOstar)
P-cadherin,Placental cadherin,CDH3,Cadherin-3 |
Sus scrofa (Pig) | P. pastoris (Yeast) |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH3/Cadherin 3 Protein, Pig, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The predicted molecular weight is 31.6 kDa and the accession number is O18926. | |||
TMPH-00291 |
Odorant-binding Protein, Bovine, Recombinant (His & SUMOstar)
|
Bovine | P. pastoris (Yeast) |
This protein binds a wide variety of chemical odorants. Odorant-binding Protein, Bovine, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 34.5 kDa and the accession number is P07435. | |||
TMPH-02508 |
Angiogenin-4 Protein, Mouse, Recombinant (His & SUMOstar)
Ang4,Angiogenin-4,EC:3.1.27.- |
Mouse | P. pastoris (Yeast) |
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). Angiogenin-4 Protein, Mouse, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 29.9 kDa and the accession number is Q3TMQ6. | |||
TMPH-02420 |
APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar)
ApoC-III,APOC3,Apolipoprotein C-III,Apo-CIII,Apolipoprotein ... |
Cynomolgus | P. pastoris (Yeast) |
APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The predicted molecular weight is 24.7 kDa and the accession number is P18659. | |||
TMPH-02415 |
Lysyl endopeptidase Protein, Lysobacter enzymogenes, Recombinant (His & SUMOstar)
|
Lysobacter enzymogenes | P. pastoris (Yeast) |
Highly specific endopeptidase that hydrolyzes lysyl bonds including the Lys-Pro bond. Lysyl endopeptidase Protein, Lysobacter enzymogenes, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The predicted molecular weight is 44.0 kDa and the accession number is Q7M135. | |||
TMPH-02528 |
SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar)
|
Mouse | P. pastoris (Yeast) |
Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse. SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar) is expressed in yeast with N-His tag. The predicted molecular weight is 22.5 kDa and the accession number is P63115. | |||
TMPH-00155 |
Barstar Protein, Bacillus amyloliquefaciens, Recombinant (His & Myc)
Barstar,Ribonuclease inhibitor |
Bacillus amyloliquefaciens | E. coli |
Inhibitor of the ribonuclease barnase. Forms a one-to-one non-covalent complex. Barstar Protein, Bacillus amyloliquefaciens, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.7 kDa and the accession number is P11540. | |||
TMPH-02765 |
LY6C1 Protein, Mouse, Recombinant (His & SUMOstar)
|
Mouse | P. pastoris (Yeast) |
N/A. LY6C1 Protein, Mouse, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The predicted molecular weight is 25.1 kDa and the accession number is P0CW02. | |||
TMPH-01816 |
OX1R Protein, Human, Recombinant (His & SUMOstar)
|
Human | P. pastoris (Yeast) |
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. OX1R Protein, Human, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 21.4 kDa and the accession number is O43613. | |||
TMPH-03644 |
Hydrophobin-2/HFB2 Protein, Trichoderma reesei, Recombinant (His & SUMOstar)
|
Hypocrea jecorina | P. pastoris (Yeast) |
Responsible for spore hydrophobicity and protection. Hydrophobin-2/HFB2 Protein, Trichoderma reesei, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The predicted molecular weight is 23.2 kDa and the accession number is P79073. | |||
TMPH-00123 |
Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His & SUMOstar)
eglD,cel61A,AA9 family lytic polysaccharide monooxygenase A,... |
Aspergillus kawachii | P. pastoris (Yeast) |
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates. Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 55.7 kDa and the accession number is Q96WQ9. | |||
TMPH-00294 |
PAG-1 Protein, Bovine, Recombinant (His & SUMOstar)
|
Bovine | P. pastoris (Yeast) |
Appears to be proteolytically inactive. PAG-1 Protein, Bovine, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 49.8 kDa and the accession number is Q29432. | |||
TMPH-02143 |
NR5A1 Protein, Human, Recombinant (His)
|
Human | E. coli |
Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cA... |