Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T23375 |
SNAP
|
Others | Others |
NO donor | |||
T8004 |
SNAP 94847 hydrochloride
|
GPR; Melanin-concentrating Hormone Receptor (MCHR) | Endocrinology/Hormones; GPCR/G Protein |
SNAP 94847 hydrochloride 是一种选择性黑色素浓缩激素受体1 拮抗剂,Ki 为 2.2 nM,具有抗抑郁样活性。它是 MCH 诱发的肌醇磷酸形成的高亲和力拮抗剂 ,pA2为 7.81。 | |||
T28822 |
SNAP 398299
SNAP-398299,SNAP398299 |
||
SNAP 398299, a galanin receptor antagonist, is a potential novel pharmacological treatment for mood disorders. | |||
T5406 |
SNAP 94847
SNAP-94847 |
GPR; Melanin-concentrating Hormone Receptor (MCHR) | Endocrinology/Hormones; GPCR/G Protein |
SNAP 94847 (SNAP-94847) 是一种选择性黑色素浓缩激素受体1 拮抗剂,Ki 为 2.2 nM。它具有抗焦虑和抗抑郁活性,可减少小鼠的食物摄入。 | |||
T5455 |
HT-2157
SNAP37889,SNAP-37889 |
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
HT-2157 (SNAP-37889) 是一种高亲和力、选择性和竞争性的甘丙肽 3 受体 (Gal3) 拮抗剂。 | |||
T16831 |
(S)-SNAP5114
|
Others; GABA Receptor | Membrane transporter/Ion channel; Neuroscience; Others |
(S)-SNAP5114 是一种选择性的 GABA 转运抑制剂,对 hGAT-3 的 IC50 为 5 μM,对 rGAT-2 的 IC50 为 21 μM。 (S)-SNAP5114 具有抗惊厥性质。 | |||
T15688 |
L-771688
SNAP 6383 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
L-771688(SNAP 6383) 是一种新型有效和选择性的 α1A-肾上腺素受体拮抗剂, Ki 值为 0.43±0.02 nM。L-771688 KE 用于治疗良性前列腺增生。 | |||
T70437 | SNAP-5089 | ||
SNAP-5089 is a highly selective alpha1A-adrenoceptor antagonist. | |||
T28823 |
SNAP-7941
SNAP7941 |
||
SNAP-7941 is a selective antagonist of the melanin concentrating hormone receptor MCH1 with promising anxiolytic, antidepressant and anorectic effects in initial animal studies. | |||
T23374 |
SNAP 5089
|
Others | Others |
α1A-adrenoceptor antagonist | |||
T34666 |
SNAP-8719
SNAP8719 |
||
SNAP-8719 is a selective antagonist of α1D-AR. SNAP-8719 showed better selectivity for α1D-AR and lower binding affinity for the 5-HT1A receptor. | |||
T12808 |
S-Nitroso-N-acetyl-DL-penicillamine
N-乙酰基-3-(硫代亚硝基)-DL-缬氨酸,SNAP |
NO Synthase | Immunology/Inflammation |
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) 是一种稳定的血小板聚集抑制剂,是一氧化氮的供体。 | |||
T6990L |
SNAP8 Acetate(868844-74-0,free base)
|
Others | Others |
SNAP8 Acetate(868844-74-0,free base) 减少皱纹出现。 | |||
T6990 |
SNAP8
Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2,SNAP 8,SNAP-8 |
Others | Others |
SNAP8 (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2) 是 SNAP-25 N 末端的模拟物,它与 SNAP-25 竞争 SNARE 复合物中的位置,从而调节其形成。 | |||
TP1576 |
SNAP-25 187-203
|
||
This amino acids187 to 203 fragment is derived from the C-terminal helix of synaptosomal-associated protein of 25 kDa (SNAP-25). This peptide is able to rescue exocytosis from botulinum neurotoxin E (BoNT/E)-treated cells, albeit at higher concentrations | |||
T39468 |
PYBG-TMR
|
||
PYBG-TMR, a fluorochrome, serves as a dye that specifically and efficiently labels genetically encoded SNAP-tags in live cells. | |||
T39469 |
PYBG-BODIPY
|
||
PYBG-BODIPY, a fluorochrome dye, specifically and efficiently labels genetically encoded SNAP-tags in live cells, serving its role as a targeted marker. | |||
T38538 | BGN3 | ||
BGN3 is a good substrate for the SNAP- tag and H 5 enzymes. The activities of SNAP- tag and H 5 enzymes on BGN3 are reasonable (IC 50 = 15.6 and 23.5 μM, respectively). | |||
T39487 |
HaXS8
|
||
HaXS8 is a dimerizer that facilitates the covalent and irreversible intracellular dimerization of proteins of interest labeled with HaloTag and SNAP-tag. Furthermore, HaXS8 does not exhibit any interference with PI3K/mTOR signaling. | |||
T78396 |
Janelia Fluor® 646 TFA
JF646 TFA |
||
Janelia Fluor® 646 TFA(JF646 TFA)是一种红色荧光染料,专用于Janelia Fluor 646 HaloTag和SNAP-Tag配体的合成,并适用于活细胞成像实验。 | |||
T39504 |
PA Janelia Fluor® 646, SE
PA-JF646-NHS |
||
PA Janelia Fluor 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag and SNAP-tag . PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λ Excitation/emission ~650/664 nm). | |||
T79925 |
T4 UvsX Recombinase
|
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
T4 UvsX Recombinase 促进双链DNA模板上DNA复制的启动,通过催化模板DNA与同源单链DNA引物间的突触形成。此酶显著增强了T4 DNA聚合酶全酶在线性单链DNA模板上进行的回跳(发夹引物)DNA合成反应。 | |||
T38156 |
N-Acetyl-DL-penicillamine
|
||
N-Acetyl-DL-penicillamine is a chelating agent.1,2,3It inhibits the binding of methyl mercury to isolated human erythrocytes by 50% and removes 50% of methyl mercury ions from methyl mercury-loaded blood cells when used at a concentration of 1 mM.1,2N-Acetyl-DL-penicillamine (3 mmol/kg per day, p.o.) reduces the biological half-life of mercury and decreases liver, kidney, brain, and blood mercury levels, as well as increases urinary excretion of mercury in a concentration-dependent manner, in mi... | |||
T82012 |
Janelia Fluor® 635, SE
JF635, NHS,JF635, SE |
||
Janelia Fluor® 635, SE(JF635, SE)为红色荧光染料,具备NHS酯基团与伯胺基共轭的特性。JF635, SE常用于作为自标记标签如HaloTag及SNAP-tag的配体,在活细胞成像领域得到应用。 |