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Cat. No. | Product Name | ||
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L9500 | 表型筛选靶点鉴定库 | 1796 compounds | |
1796 种靶点明确的已知活性化合物,适合表型筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0379 |
Risedronic Acid
Risedronate,利塞膦酸 |
Others; Transferase | Metabolism; Others |
Risedronic Acid (Risedronate) 具有抑制破骨细胞介导的骨重吸收的作用。 | |||
T1041 |
Risedronate Sodium
NE 58095 Sodium,Risedronic Acid Sodium,利塞膦酸钠,利赛膦酸钠 |
HBV; Transferase | Metabolism; Microbiology/Virology |
Risedronate Sodium (NE 58095 Sodium) 是一种双磷酸盐,对破骨细胞介导的骨吸收具有抑制作用。 | |||
T5437 |
Gefitinib-based PROTAC 3
|
EGFR; PROTACs | Angiogenesis; JAK/STAT signaling; PROTAC; Tyrosine Kinase/Adaptors |
Gefitinib-based PROTAC 3 通过 linker 将 EGFR 结合元件与 von Hippel-Lindau 配体结合,在 HCC827(外显子 19 del)和 H3255(L858R 突变)细胞中诱导 EGFR 降解,DC50 分别为 11.7 和 22.3 nM。 | |||
T23445 |
Anxiolytic/nonsedative agent-1
TCS 1205 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Anxiolytic/nonsedative agent-1 (TCS 1205) 是一种有效的选择性 GABAA 激动剂。Anxiolytic/nonsedative agent-1 对牛脑膜中的 BzR 显示出明显的亲和力,对 α1β2γ2、α2β2γ2、α5β3γ2 的 Kis 分别为 14、121、239 nM。Anxiolytic/nonsedative agent-1 在体外表现出 α2 选择性功效,在体内表现出抗焦虑选择性作用。 | |||
T6301 |
Tosedostat
CHR-2797,托舍多特 |
Aminopeptidase; AChR | Metabolism; Neuroscience |
Tosedostat (CHR-2797) 是一种具有口服活性的氨基肽酶(aminopeptidase) 抑制剂,对多种肿瘤细胞系均具有抗增殖作用。 | |||
T28087 |
Mosedipimod
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Mosedipimod is an immunomodulator. | |||
T131569 |
Allosedamine
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Allosedamine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131569。 | |||
T60483 |
Fasedienol
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Fasedienol 是一种犁鼻器 (VON) 的神经化学刺激剂,可缓解焦虑和经前综合症。 | |||
T37989 |
D-Sedoheptulose-7-phosphate (barium salt)
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D-Sedoheptulose-7-phosphate is an intermediate in the pentose phosphate pathway. [1] [2] In this pathway, transaldolase catalyzes the transfer of a three carbon dihydroxyacetone moiety from D-sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to generate D-fructose-6-phosphate . D-Sedoheptulose-7-phosphate is also an intermediate in carbon fixation in photosynthetic organisms, as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics. [3] | |||
TNU0038 | 3-Methylpsedouridine | ||
Nucleoside Derivatives - C-nucleosides, N-Methyl nucleosides; Naturally modified Ribo-nucleosides | |||
T24777 |
Sedecamycin
T-2636A,T-2636,Ro 23-0731/000,NSC 145117 |
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Sedecamycin is a 17-membered macrolide antibiotic. It is used for treating swine dysentery. | |||
T124564 | Resedine | ||
Resedine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124564,CAS号为 60426-44-0。 | |||
T81148 |
Smac-based peptide
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Smac-based peptide为具有生物活性的肽,源自SMAC与BIR3结构域的结合。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5763 |
Sedanolide
|
Others; Autophagy | Autophagy; Others |
Sedanolide 是从伞形科的种子油中分离出的一种天然苯酞,具有抗炎和抗氧化活性。 | |||
T13816 |
(+)-Peusedanol
(+)-白花前胡醇,白花前胡醇 |
Others | Others |
(+)-Peusedanol 是一种香豆素,从滨海前胡中分离出来。 | |||
TN4612 |
(+)-N-Methylallosedridine
|
Others | Others |
(+)-N-Methylallosedridine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4612,CAS号为 41447-16-9。 | |||
T19268 |
D-Sedoheptulose 7-phosphate
|
Others | Others |
D-Sedoheptulose 7-phosphate is a common precursor of heptaic acid (group III) and hygromycin B (group IV) heptasaccharide. D-heptadecane 7-phosphate can be converted to NDP-heptose by similar biosynthetic pathways in these compounds. | |||
TN4615 | (-)-N-Methylsedridine | Others | Others |
(-)-N-Methylsedridine是一种天然产物,属于景天科景天属,其产品编号为 TN4615,CAS号为 41447-15-8。(-)-N-Methylsedridine可用作对照参考。 | |||
TN7007 |
Sedoheptulose anhydride monohydrate
|
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Sedoheptulose anhydride monohydrate is a natural product. |
Cat. No. | Product Name | Species | Expression System |
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TMPH-03544 |
Enterotoxin type D Protein, S. aureus, Recombinant (His & SUMO)
entD,SED,Enterotoxin type D |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. In addition, induces B-cell proliferation and differentiation in the presence of T-cells. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type D P... | |||
TMPY-02836 |
MFGE8 Protein, Human, Recombinant (His)
SPAG10,HMFG,milk fat globule-EGF factor 8 protein,hP47,BA46,... |
Human | Baculovirus Insect Cells |
MFGE8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q08431-1. | |||
TMPK-00850 |
MFGE8 Protein, Mouse, Recombinant (His)
MFG-E8,Lactadherin,SPAG10,BA46,MFG1,SED1,EDIL1,MP47... |
Mouse | HEK293 Cells |
MFGE8 (Milk Fat Globule EGF And Factor V/VIII Domain Containing) is a Protein Coding gene. Diseases associated with MFGE8 include Anal Paget's Disease and Topographical Agnosia. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Extracellular vesicle-mediated signaling in recipient cells. This protein plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. | |||
TMPY-05235 |
MFGE8 Protein, Human, Recombinant (His & Avi), Biotinylated
HsT19888,SPAG10,MFGM,MFG-E8,OAcGD3S,milk fat globule-EGF fac... |
Human | Baculovirus Insect Cells |
MFGE8 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 44.1 kDa and the accession number is Q08431.2. | |||
TMPY-01860 |
Collagen II/COL2A1 Protein, Human, Recombinant (aa 1242-1487, His)
SEDC,collagen, type II, alpha 1,COL11A3,AOM,STL1,co... |
Human | HEK293 Cells |
COL2A1 is the alpha-1 chain of type II collagen which is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this protein are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of th... | |||
TMPY-01852 |
CHST3 Protein, Mouse, Recombinant (His)
C6ST-1,carbohydrate (chondroitin 6) sulfotransferase 3,GST-0... |
Mouse | HEK293 Cells |
Carbohydrate sulfotransferase 3, also known as Chondroitin 6-O-sulfotransferase 1, Chondroitin 6-sulfotransferase and CHST3, is a single-pass type II membrane protein which belongs to thesulfotransferase 1 family and Gal / GlcNAc / GalNAc subfamily. CHST3 is widely expressed in adult tissues. It is expressed in heart, placenta, skeletal muscle and pancreas. CHST3 is also expressed in various immune tissues such as spleen, lymph node, thymus and appendix. CHST3 catalyzes the transfer of su... |