Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0162 |
Quetiapine
ICI204636,Quetiapin,喹硫平 |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; AChR; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Quetiapine (ICI204636) 是5-HT 受体激动剂和多巴胺受体拮抗剂,对人5-HT1A 的 pEC50值为 4.77,对人 D2的 pIC50值为 6.33。它用于治疗精神分裂症,以及治疗与 I 型双相情感障碍相关的急性躁狂发作。它对人 D2、HT1、5-HT2A、5-HT2C 受体具有中高等亲和力,pKi 值为 7.25、5.74、7.54和5.55。 | |||
T6241 |
Quetiapine hemifumarate
Quetiapine Fumarate,ICI-204636,富马酸喹硫平 |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Quetiapine hemifumarate (ICI-204636) 是5-HT 受体激动剂和多巴胺受体拮抗剂,对人5-HT1A 和人D2的pEC50值分别为 4.77 和 6.33,具有抗抑郁和抗焦虑作用。 | |||
T12619 |
Quetiapine sulfoxide
Quetiapine S-oxide |
Others | Others |
Quetiapine sulfoxide is a main Quetiapinem metabolite. Quetiapine is a agonist of 5-HT receptors and a antagonist of dopamine receptor.Quetiapine is a second-generation antipsychotic. | |||
T12618 |
Quetiapine-d4 fumarate
Quetiapine D4 fumarate,富马酸奎硫平 D4 |
Others | Others |
Quetiapine D4 fumarate is the deuterium labeled Quetiapine fumarate. Quetiapine fumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with antidepressant and anxiolytic. | |||
T12619L2 |
Quetiapine sulfoxide hydrochloride
Quetiapine S-oxide hydrochloride,Quetiapine sulfoxide hydrochloride (329216-63-9 free base) |
Others | Others |
Quetiapine sulfoxide hydrochloride is a main metabolite of Quetiapinem. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist. | |||
T12619L |
Quetiapine sulfoxide dihydrochloride
Quetiapine S-oxide dihydrochloride,喹硫平亚砜双盐酸盐 |
Others | Others |
Quetiapine sulfoxide dihydrochloride is a main Quetiapinem metabolite. Quetiapine is a agonist of 5-HT receptors and a antagonist of dopamine receptor.Quetiapine is a second-generation antipsychotic. | |||
T12618L |
Quetiapine-d4 hemifumarate
半富马酸奎硫平 D4 |
Others | Others |
Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with ntidepressant and anxiolytic. | |||
T125035 | Quetiapine hydroxy impurity | ||
Quetiapine hydroxy impurity 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125035,CAS号为 329216-67-3。 | |||
T68706 |
Olanzapine HCl
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Olanzapine HCl is an atypical antipsychotic. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder. Olanzapine is structurally similar to clozapine and quetiapine. It is a dopamine antagonist and is classified as a thienobenzodiazepine. |