Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0162 |
Quetiapine
ICI204636,Quetiapin,喹硫平 |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; AChR; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Quetiapine (ICI204636) 是5-HT 受体激动剂和多巴胺受体拮抗剂,对人5-HT1A 的 pEC50值为 4.77,对人 D2的 pIC50值为 6.33。它用于治疗精神分裂症,以及治疗与 I 型双相情感障碍相关的急性躁狂发作。它对人 D2、HT1、5-HT2A、5-HT2C 受体具有中高等亲和力,pKi 值为 7.25、5.74、7.54和5.55。 | |||
T6241 |
Quetiapine hemifumarate
Quetiapine Fumarate,ICI-204636,富马酸喹硫平 |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Quetiapine hemifumarate (ICI-204636) 是5-HT 受体激动剂和多巴胺受体拮抗剂,对人5-HT1A 和人D2的pEC50值分别为 4.77 和 6.33,具有抗抑郁和抗焦虑作用。 | |||
T12618 |
Quetiapine-d4 fumarate
Quetiapine D4 fumarate,富马酸奎硫平 D4 |
Others | Others |
Quetiapine D4 fumarate is the deuterium labeled Quetiapine fumarate. Quetiapine fumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with antidepressant and anxiolytic. | |||
T12619 |
Quetiapine sulfoxide
Quetiapine S-oxide |
Others | Others |
Quetiapine sulfoxide is a main Quetiapinem metabolite. Quetiapine is a agonist of 5-HT receptors and a antagonist of dopamine receptor.Quetiapine is a second-generation antipsychotic. | |||
T12619L |
Quetiapine sulfoxide dihydrochloride
Quetiapine S-oxide dihydrochloride,喹硫平亚砜双盐酸盐 |
Others | Others |
Quetiapine sulfoxide dihydrochloride is a main Quetiapinem metabolite. Quetiapine is a agonist of 5-HT receptors and a antagonist of dopamine receptor.Quetiapine is a second-generation antipsychotic. | |||
T125035 | Quetiapine hydroxy impurity | ||
Quetiapine hydroxy impurity 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125035,CAS号为 329216-67-3。 | |||
T12618L |
Quetiapine-d4 hemifumarate
半富马酸奎硫平 D4 |
Others | Others |
Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with ntidepressant and anxiolytic. | |||
T12619L2 |
Quetiapine sulfoxide hydrochloride
Quetiapine S-oxide hydrochloride,Quetiapine sulfoxide hydrochloride (329216-63-9 free base) |
Others | Others |
Quetiapine sulfoxide hydrochloride is a main metabolite of Quetiapinem. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist. |