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Cat. No.	Product Name	Target	Signaling Pathways
T8708	Paroxetine	Serotonin Transporter	Neuroscience
	Paroxetine 是选择性血清素再摄取抑制剂，是苯基哌啶的衍生物。它对于甲肾上腺素摄取抑制功能较弱，但比该位点其他SSRIs 更有效。
T1636L	Paroxetine hydrochloride hemihydrate Paroxetine Hydrochloride,Paxil,Paroxetine HCl,Seroxat	5-HT Receptor	GPCR/G Protein; Neuroscience
	Paroxetine hydrochloride hemihydrate (Paxil) 是一种抗抑郁药，为高效的五羟色胺再摄取抑制剂，能抑制 GRK2 活性，IC50 为 14 μM。
T1636	Paroxetine hydrochloride Paroxetine HCl,BRL29060 hydrochloride,FG-7051,BRL29060A,盐酸帕罗西汀	5-HT Receptor; Serotonin Transporter; GRK; AChR; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Paroxetine hydrochloride (Paroxetine HCl) 是一种血清素摄取抑制剂，能抑制 GRK2 活性，IC50值为 14 μM。它可研究抑郁症。
T20531	Paroxetine maleate Paroxetine maleate salt
	Paroxetine maleate is a selective inhibitor of serotonin reuptake and an antidepressant.
T35920	N-methyl Paroxetine
	N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM). It inhibits serotonin uptake in rat brain synaptosomes with an IC50 value of 22 nM. N-methyl Paroxetine has been used as a precursor in the synthesis of paroxetine and is a potential impurity in commercial preparations of paroxetine.
T37308	Desmethylene Paroxetine hydrochloride	Drug Metabolite	Metabolism
	Desmethylene Paroxetine hydrochloride 是 Paroxetine 的非共轭代谢产物，是一种儿茶酚中间体。
T22395	Paroxetine mesylate	Others	Others
	Paroxetine Mesylate, the mesylate salt form of paroxetine, is a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with anxiolytic and antidepressant properties.
T69008	Paroxol methanesulfonate
	Paroxol methanesulfonate is an intermediate in the synthesis of Paroxetine, a selective serotonin reuptake inhibitor.
T35875	CCG258208 hydrochloride
	GRKs-IN-1 hydrochloride, Compound 14as, has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50=130 nM) and GRK5 (IC50=7.1 μM).GRKs-IN-1 hydrochloride is a derivative 14as of paroxetine, shows a 100-fold improvement in cardiomyocyte contractility assays over paroxetine[1]. [1]. Waldschmidt HV, et al. Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2Inhibitors Based on Paroxetine. J Med Chem. 2017 Apr 13;60(7):305...
T31108	CTP-347 CTP347,CTP 347
	CTP-347, a deuterated version of paroxetine, is potentially the best non-hormonal drug in its class for the treatment of hot flashes.