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Targets Recommended: Apoptosis VEGFR Bcr-Abl PDGFR Src mTOR Hck

1

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T2415 PP121

Apoptosis; VEGFR; Bcr-Abl; PDGFR; Src; mTOR; Hck Angiogenesis; Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
PP121是一种多靶点激酶抑制剂,抑制 PDGFR、Hck、mTOR、VEGFR2、Src、Abl、DNK-PK 的 IC50值分别为2、8、10、12、14、18、60 nM。

化合物

PP121
Cat.No: T2415
Synonym:
Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck
Cat. No. Product Name Species Expression System
TMPJ-00811 IGFBP-1 Protein, Human, Recombinant (His)

Insulin-like growth factor-binding protein 1,PP...

Human HEK293 Cells
Insulin-like growth factor-binding protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature protein. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. Regulation of Insulin-like Growth Factor (IGF) transp...
TMPK-00083 IGF1/IGF-I Protein, Human, Recombinant (hFc)

IGF1A,胰岛素样生长因子,IBP1,IGF-I,MGF

Human HEK293 Cells
The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins.Insulin-like growth factor I (IGF-I) is a polypeptide hormone produced mainly by the liver in response to the endocrine GH stimulus, but it is also secreted by multiple tissues for autocrine/paracrine purposes.

重组蛋白

IGFBP-1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00811
Species: Human
Expression System: HEK293 Cells
IGF1/IGF-I Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00083
Species: Human
Expression System: HEK293 Cells
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