31
2
7
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9911 |
Tocilizumab
|
Interleukin | Immunology/Inflammation |
Tocilizumab 是抗人白细胞介素-6 受体 (IL-6R) 的中和抗体,能够阻碍 IL-6 与 IL-6R 的结合,进而抑制经典和反式信号。它可用于研究类风湿性关节炎,对重症 COVID-19 冠状病毒病方面的研究具有显著效果。 | |||
T0049 |
Azlocillin sodium salt
Sodium azlocillin,Azlocillin sodium,阿洛西林钠 |
Antibacterial; Antibiotic; Parasite | Microbiology/Virology |
Azlocillin sodium salt 是一种半合成青霉素,是内酰胺类广谱抗生素。它具有抗假单胞杆菌的活性,并对抗寄生虫Plasmodium falciparum 有效。 | |||
T3320 |
Dizocilpine Maleate
(+)-Mk-801 Hydrogen Maleate,MK 801,地卓亚平马来酸盐,Dizocilpine hydrogen maleate,地佐环平马来酸盐,(+)-MK 801 maleate,(+)-MK 801 (Maleate) |
NMDAR; iGluR | Membrane transporter/Ion channel; Neuroscience |
Dizocilpine Maleate (MK 801) 是一种选择性和非竞争性的 NMDA 受体拮抗剂,Kd 值为 37.2 nM。它用于治疗 NMDA 受体可能发挥重要作用的多种神经退行性疾病或疾病。 | |||
T2369 |
Rociletinib
AVL-301,CNX-419,CO-1686 |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Rociletinib (CNX-419) 是一种可口服的EGFR 抑制剂,能够抑制 EGFRL858R/T790M 和 EGFRWT 的活性,IC50值分别为 21.5 nM 和 303.3 nM。 | |||
T13869L |
Ribocil
|
Antibacterial | Microbiology/Virology |
Ribocil 强烈抑制GFP 表达, EC50值为0.3 μM,是一种高选择性化学调节剂,调节细菌核糖核黄素核开关。 | |||
T6259 |
Dizocilpine
地佐环平,MK-801 |
NMDAR; iGluR | Membrane transporter/Ion channel; Neuroscience |
Dizocilpine (MK-801) 是一种选择性非竞争性NMDA 受体拮抗剂,Kd=37.2 nM,是一种抗惊厥剂。它通过与 NMDA 相关离子通道内的一个位点结合而起作用,从而阻止 Ca2+的流动。 | |||
T6352 |
(-)-Dizocilpine maleate
C13737,(-)-MK 801 (Maleate),(-)-MK 801马来酸,(-)-MK 801 Maleate |
NMDAR; iGluR | Membrane transporter/Ion channel; Neuroscience |
(-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) 是一种选择性且非竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂,Ki 为 211.7 nM。它是一种 Dizocilpine 的活性较低的 (-)-对映体,具有抗抑郁作用。 | |||
T4208 |
Targocil
|
Antibacterial | Microbiology/Virology |
Targocil 是一种磷壁酸生物合成的抑菌抑制剂,可抑制甲氧西林敏感金黄色葡萄球菌 (MSSA) 和耐甲氧西林金黄色葡萄球菌 (MRSA) 的生长,对于 MRSA 和 MSSA 的MIC90值都为 2 μg/mL。 | |||
T6582 |
Mezlocillin Sodium
美洛西林钠,Baycipen |
Antibacterial; Antibiotic | Microbiology/Virology |
Mezlocillin Sodium (Baycipen) 是一种青霉素 β-内酰胺类抗生素,用于治疗由易感染微生物引起的细菌感染。 | |||
T75324 | Azidocillin | ||
Azidocillin 是一种半合成青霉素,是一种具有口服活性的 β-内酰胺类抗生素 (antibiotic)。Azidocillin 具有叠氮化功能,并在细菌内 (bacteria) 保持靶向活性。Azidocillin 可用于研究牙科手术引起的骨炎,或中耳炎、肠球菌败血症和其他细菌感染性疾病。 | |||
T12723 | Ribocil-C R enantiomer | Others | Others |
Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor. | |||
T27585 |
Idrocilamide
Brolitene |
||
Idrocilamide exhibits muscle relaxant and anti-inflammatory properties. | |||
T40699 |
Temocillin disodium
BRL 17421 disodium |
||
Temocillin disodium, a 6-α-methoxy penicillin, possesses antibacterial activity. | |||
T12722 |
Ribocil-C Racemate
|
Others | Others |
Ribocil-C Racemate 是 Ribocil-C 的外消旋体。Ribocil-C 是具有高度选择性的,细菌核黄素核糖开关 (bacterial riboflavin riboswitches) 抑制剂。 | |||
T13869 |
Ribocil B
Ribocil S enantiomer,ent-Ribocil A |
Others | Others |
Ribocil-B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN,KD of 6.6 nM). | |||
T30981 |
Clometocillin
Penicilline 356 |
||
Clometocillin is a penicillin that can active penicillin to pen-I or pen-R pneumococci. | |||
T30040 |
Amphocil
Amphotericin B cholesteryl sulfate |
||
Amphocil is used to treat patients with invasive fungal infection. | |||
T14993 |
Rociletinib hydrobromide
AVL-301 hydrobromide,CO-1686 (hydrobromide),CNX-419 hydrobromide |
Others | Others |
Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT). | |||
T21105 |
Azlocillin
Azlocilline,Azlin |
||
Azlocillin is a semisynthetic ampicillin-derived penicillin belonging to acylureido. | |||
T13149 |
Thiocillin I
|
Antibacterial | Microbiology/Virology |
Thiocillin I is a thiopeptide antibiotic and has in vitro antibacterial activity against Gram-positive bacterial strains(MIC of Thiocillin I against S. aureus 1974149, E. faecalis 1674621, B. subtilis ATCC 6633 and S. pyogenes 1744264 are 2 μg/mL, 0.5 μg/mL, 4 μg/mL and 0.5 μg/mL, respectively). | |||
T125095 |
Monocillinol B
|
||
T24179 |
Isocil
Hyvar,Herbicide 82 |
||
Isocil is a pesticide. | |||
T32388 |
Ketocillin sodium
|
||
Ketocillin sodium is a semisynthetic penicillin. | |||
T29959 |
Amdinocillin methylacetate
Mecillinam acetylmethyl ester |
||
Amdinocillin methylacetate is a Synthetic penicillin. | |||
T74378 |
Temocillin
|
||
Temocillin为6-α-甲氧基青霉素衍生物,为半合成β-内酰胺类抗生素,对多数需氧革兰氏阴性菌展现特定抗菌活性。 | |||
T12722L |
Ribocil-C
|
Antibacterial | Microbiology/Virology |
Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor. | |||
TP2396 |
Ociltide
Ociltidum |
||
Ociltide is a bioactive chemical. | |||
T6582L |
Mezlocillin
Bay-f 1353,Meslocillin,Melocin,Baypen,Mezlin |
||
Meloxicillin is a broad-spectrum penicillin antibiotic that is active against both Gram-negative bacteria and some Gram-positive bacteria. Unlike most other broad-spectrum penicillin, it is excreted by the liver and can therefore be used to treat biliary | |||
T25072 |
Amantocillin
|
||
Amantocillin is an antibiotic. | |||
T31898 |
Fuzlocillin
Fuzlocillinum,Fuzlocilline |
||
Fuzlocillin is a bio-active chemical. Detailed information has not been published. | |||
T30271 |
Azidocillin sodium salt
Nalpen,Globacillin,Longatren |
||
Azidocillin sodium salt is a type of penicillin. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17261 |
Xantocillin
|
Others | Others |
Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway. | |||
T13967 |
Xanthocillin X permethyl ether
|
Others | Others |
Xanthocillin X permethyl ether is a natural product isolated from fungal extracts, has Aβ-42 lowering activity. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01231 |
CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated
OCILmember D,LLT1,CLAX,CLEC2D,CLAXLLT-1,LLT-1,O... |
Human | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies. | |||
TMPK-01230 |
CLEC2D Protein, Human, Recombinant (hFc & Avi)
Lectin-like NK cell receptor,LLT-1,OCIL,LLT1,Lectin... |
Human | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies. However, this implication may be confounded by highly active anti-retroviral treatment (HAART). | |||
TMPJ-01252 |
CLEC2D Protein, Mouse, Recombinant (His)
Clec2d,Clr-b,Clrb,Ocil,Osteoclast inhibitory lectin... |
Mouse | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and immunity. The C-type lectin receptor Clec2d as a sensor of cell death, which directly detects histones released during necrosis and thus contributes to inflammation and immunopathology. The Clec2d pathway may also be exploited to favor a pro-inflammatory anti-tumor response. And tu... | |||
TMPY-02248 |
Myocilin Protein, Human, Recombinant (His)
myocilin, trabecular meshwork inducible glucocortic... |
Human | HEK293 Cells |
Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC, and GLC1A, is a protein that contains one olfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid outflow in the trabecular meshwork. Myocilin / MYOC is expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart, and other tissues. Myocilin / MYOC is expressed predominantly in the retina. In normal eyes, it is found in the ... | |||
TMPH-02792 |
Myocilin Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Myocilin Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.4 kDa and the accession number is O70624. | |||
TMPH-02793 |
Myocilin Protein, Mouse, Recombinant (His & Myc)
|
Mouse | Baculovirus Insect Cells |
Myocilin Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 35.2 kDa and the accession number is O70624. | |||
TMPY-04040 |
CLEC2D Protein, Rat, Recombinant (hFc)
C-type lectin domain family 2, member D |
Rat | HEK293 Cells |
Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were detected primarily in hematopoietic cell lines and were found to be co-induced by the same activation signals. Although very low amounts of putative soluble CLEC2D protein isoforms could be produced by transfectants, CLEC2D isoforms 2 and 4 were efficiently expressed. CLEC2D uses g... |