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Targets Recommended: Interleukin

31

抑制剂 & 化合物

2

天然产物

7

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9911 Tocilizumab

Interleukin Immunology/Inflammation
Tocilizumab 是抗人白细胞介素-6 受体 (IL-6R) 的中和抗体,能够阻碍 IL-6 与 IL-6R 的结合,进而抑制经典和反式信号。它可用于研究类风湿性关节炎,对重症 COVID-19 冠状病毒病方面的研究具有显著效果。
T0049 Azlocillin sodium salt

Sodium azlocillin,Azlocillin sodium,阿洛西林钠

Antibacterial; Antibiotic; Parasite Microbiology/Virology
Azlocillin sodium salt 是一种半合成青霉素,是内酰胺类广谱抗生素。它具有抗假单胞杆菌的活性,并对抗寄生虫Plasmodium falciparum 有效。
T3320 Dizocilpine Maleate

(+)-Mk-801 Hydrogen Maleate,MK 801,地卓亚平马来酸盐,Dizocilpine hydrogen maleate,地佐环平马来酸盐,(+)-MK 801 maleate,(+)-MK 801 (Maleate)

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
Dizocilpine Maleate (MK 801) 是一种选择性和非竞争性的 NMDA 受体拮抗剂,Kd 值为 37.2 nM。它用于治疗 NMDA 受体可能发挥重要作用的多种神经退行性疾病或疾病。
T2369 Rociletinib

AVL-301,CNX-419,CO-1686

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Rociletinib (CNX-419) 是一种可口服的EGFR 抑制剂,能够抑制 EGFRL858R/T790M 和 EGFRWT 的活性,IC50值分别为 21.5 nM 和 303.3 nM。
T13869L Ribocil

Antibacterial Microbiology/Virology
Ribocil 强烈抑制GFP 表达, EC50值为0.3 μM,是一种高选择性化学调节剂,调节细菌核糖核黄素核开关。
T6259 Dizocilpine

地佐环平,MK-801

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
Dizocilpine (MK-801) 是一种选择性非竞争性NMDA 受体拮抗剂,Kd=37.2 nM,是一种抗惊厥剂。它通过与 NMDA 相关离子通道内的一个位点结合而起作用,从而阻止 Ca2+的流动。
T6352 (-)-Dizocilpine maleate

C13737,(-)-MK 801 (Maleate),(-)-MK 801马来酸,(-)-MK 801 Maleate

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
(-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) 是一种选择性且非竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂,Ki 为 211.7 nM。它是一种 Dizocilpine 的活性较低的 (-)-对映体,具有抗抑郁作用。
T4208 Targocil

Antibacterial Microbiology/Virology
Targocil 是一种磷壁酸生物合成的抑菌抑制剂,可抑制甲氧西林敏感金黄色葡萄球菌 (MSSA) 和耐甲氧西林金黄色葡萄球菌 (MRSA) 的生长,对于 MRSA 和 MSSA 的MIC90值都为 2 μg/mL。
T6582 Mezlocillin Sodium

美洛西林钠,Baycipen

Antibacterial; Antibiotic Microbiology/Virology
Mezlocillin Sodium (Baycipen) 是一种青霉素 β-内酰胺类抗生素,用于治疗由易感染微生物引起的细菌感染。
T75324 Azidocillin

Azidocillin 是一种半合成青霉素,是一种具有口服活性的 β-内酰胺类抗生素 (antibiotic)。Azidocillin 具有叠氮化功能,并在细菌内 (bacteria) 保持靶向活性。Azidocillin 可用于研究牙科手术引起的骨炎,或中耳炎、肠球菌败血症和其他细菌感染性疾病。
T12723 Ribocil-C R enantiomer

Others Others
Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor.
T27585 Idrocilamide

Brolitene

Idrocilamide exhibits muscle relaxant and anti-inflammatory properties.
T40699 Temocillin disodium

BRL 17421 disodium

Temocillin disodium, a 6-α-methoxy penicillin, possesses antibacterial activity.
T12722 Ribocil-C Racemate

Others Others
Ribocil-C Racemate 是 Ribocil-C 的外消旋体。Ribocil-C 是具有高度选择性的,细菌核黄素核糖开关 (bacterial riboflavin riboswitches) 抑制剂。
T13869 Ribocil B

Ribocil S enantiomer,ent-Ribocil A

Others Others
Ribocil-B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN,KD of 6.6 nM).
T30981 Clometocillin

Penicilline 356

Clometocillin is a penicillin that can active penicillin to pen-I or pen-R pneumococci.
T30040 Amphocil

Amphotericin B cholesteryl sulfate

Amphocil is used to treat patients with invasive fungal infection.
T14993 Rociletinib hydrobromide

AVL-301 hydrobromide,CO-1686 (hydrobromide),CNX-419 hydrobromide

Others Others
Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).
T21105 Azlocillin

Azlocilline,Azlin

Azlocillin is a semisynthetic ampicillin-derived penicillin belonging to acylureido.
T13149 Thiocillin I

Antibacterial Microbiology/Virology
Thiocillin I is a thiopeptide antibiotic and has in vitro antibacterial activity against Gram-positive bacterial strains(MIC of Thiocillin I against S. aureus 1974149, E. faecalis 1674621, B. subtilis ATCC 6633 and S. pyogenes 1744264 are 2 μg/mL, 0.5 μg/mL, 4 μg/mL and 0.5 μg/mL, respectively).
T125095 Monocillinol B

T24179 Isocil

Hyvar,Herbicide 82

Isocil is a pesticide.
T32388 Ketocillin sodium

Ketocillin sodium is a semisynthetic penicillin.
T29959 Amdinocillin methylacetate

Mecillinam acetylmethyl ester

Amdinocillin methylacetate is a Synthetic penicillin.
T74378 Temocillin

Temocillin为6-α-甲氧基青霉素衍生物,为半合成β-内酰胺类抗生素,对多数需氧革兰氏阴性菌展现特定抗菌活性。
T12722L Ribocil-C

Antibacterial Microbiology/Virology
Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor.
TP2396 Ociltide

Ociltidum

Ociltide is a bioactive chemical.
T6582L Mezlocillin

Bay-f 1353,Meslocillin,Melocin,Baypen,Mezlin

Meloxicillin is a broad-spectrum penicillin antibiotic that is active against both Gram-negative bacteria and some Gram-positive bacteria. Unlike most other broad-spectrum penicillin, it is excreted by the liver and can therefore be used to treat biliary
T25072 Amantocillin

Amantocillin is an antibiotic.
T31898 Fuzlocillin

Fuzlocillinum,Fuzlocilline

Fuzlocillin is a bio-active chemical. Detailed information has not been published.
T30271 Azidocillin sodium salt

Nalpen,Globacillin,Longatren

Azidocillin sodium salt is a type of penicillin.

化合物

Tocilizumab
Cat.No: T9911
Synonym:
Target: Interleukin
Azlocillin sodium salt
Cat.No: T0049
Synonym: Sodium azlocillin,Azlocillin sodium,阿洛西林钠
Target: Antibacterial, Antibiotic, Parasite
Dizocilpine Maleate
Cat.No: T3320
Synonym: (+)-Mk-801 Hydrogen Maleate,MK 801,地卓亚平马来酸盐,Dizocilpine hydrogen maleate,地佐环平马来酸盐,(+)-MK 801 maleate,(+)-MK 801 (Maleate)
Target: NMDAR, iGluR
Rociletinib
Cat.No: T2369
Synonym: AVL-301,CNX-419,CO-1686
Target: EGFR
Ribocil
Cat.No: T13869L
Synonym:
Target: Antibacterial
Dizocilpine
Cat.No: T6259
Synonym: 地佐环平,MK-801
Target: NMDAR, iGluR
(-)-Dizocilpine maleate
Cat.No: T6352
Synonym: C13737,(-)-MK 801 (Maleate),(-)-MK 801马来酸,(-)-MK 801 Maleate
Target: NMDAR, iGluR
Targocil
Cat.No: T4208
Synonym:
Target: Antibacterial
Mezlocillin Sodium
Cat.No: T6582
Synonym: 美洛西林钠,Baycipen
Target: Antibacterial, Antibiotic
Azidocillin
Cat.No: T75324
Synonym:
Target:
Ribocil-C R enantiomer
Cat.No: T12723
Synonym:
Target: Others
Idrocilamide
Cat.No: T27585
Synonym: Brolitene
Target:
Temocillin disodium
Cat.No: T40699
Synonym: BRL 17421 disodium
Target:
Ribocil-C Racemate
Cat.No: T12722
Synonym:
Target: Others
Ribocil B
Cat.No: T13869
Synonym: Ribocil S enantiomer,ent-Ribocil A
Target: Others
Clometocillin
Cat.No: T30981
Synonym: Penicilline 356
Target:
Amphocil
Cat.No: T30040
Synonym: Amphotericin B cholesteryl sulfate
Target:
Rociletinib hydrobromide
Cat.No: T14993
Synonym: AVL-301 hydrobromide,CO-1686 (hydrobromide),CNX-419 hydrobromide
Target: Others
Azlocillin
Cat.No: T21105
Synonym: Azlocilline,Azlin
Target:
Thiocillin I
Cat.No: T13149
Synonym:
Target: Antibacterial
Monocillinol B
Cat.No: T125095
Synonym:
Target:
Isocil
Cat.No: T24179
Synonym: Hyvar,Herbicide 82
Target:
Ketocillin sodium
Cat.No: T32388
Synonym:
Target:
Amdinocillin methylacetate
Cat.No: T29959
Synonym: Mecillinam acetylmethyl ester
Target:
Temocillin
Cat.No: T74378
Synonym:
Target:
Ribocil-C
Cat.No: T12722L
Synonym:
Target: Antibacterial
Ociltide
Cat.No: TP2396
Synonym: Ociltidum
Target:
Mezlocillin
Cat.No: T6582L
Synonym: Bay-f 1353,Meslocillin,Melocin,Baypen,Mezlin
Target:
Amantocillin
Cat.No: T25072
Synonym:
Target:
Fuzlocillin
Cat.No: T31898
Synonym: Fuzlocillinum,Fuzlocilline
Target:
Azidocillin sodium salt
Cat.No: T30271
Synonym: Nalpen,Globacillin,Longatren
Target:
Cat. No. Product Name Target Signaling Pathways
T17261 Xantocillin

Others Others
Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.
T13967 Xanthocillin X permethyl ether

Others Others
Xanthocillin X permethyl ether is a natural product isolated from fungal extracts, has Aβ-42 lowering activity.

天然产物

Xantocillin
Cat.No: T17261
Synonym:
Target: Others
Xanthocillin X permethyl ether
Cat.No: T13967
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPK-01231 CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated

OCILmember D,LLT1,CLAX,CLEC2D,CLAXLLT-1,LLT-1,O...

Human HEK293 Cells
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies.
TMPK-01230 CLEC2D Protein, Human, Recombinant (hFc & Avi)

Lectin-like NK cell receptor,LLT-1,OCIL,LLT1,Lectin...

Human HEK293 Cells
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies. However, this implication may be confounded by highly active anti-retroviral treatment (HAART).
TMPJ-01252 CLEC2D Protein, Mouse, Recombinant (His)

Clec2d,Clr-b,Clrb,Ocil,Osteoclast inhibitory lectin...

Mouse HEK293 Cells
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and immunity. The C-type lectin receptor Clec2d as a sensor of cell death, which directly detects histones released during necrosis and thus contributes to inflammation and immunopathology. The Clec2d pathway may also be exploited to favor a pro-inflammatory anti-tumor response. And tu...
TMPY-02248 Myocilin Protein, Human, Recombinant (His)

myocilin, trabecular meshwork inducible glucocortic...

Human HEK293 Cells
Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC, and GLC1A, is a protein that contains one olfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid outflow in the trabecular meshwork. Myocilin / MYOC is expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart, and other tissues. Myocilin / MYOC is expressed predominantly in the retina. In normal eyes, it is found in the ...
TMPH-02792 Myocilin Protein, Mouse, Recombinant (His)

Mouse E. coli
Myocilin Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.4 kDa and the accession number is O70624.
TMPH-02793 Myocilin Protein, Mouse, Recombinant (His & Myc)

Mouse Baculovirus Insect Cells
Myocilin Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 35.2 kDa and the accession number is O70624.
TMPY-04040 CLEC2D Protein, Rat, Recombinant (hFc)

C-type lectin domain family 2, member D

Rat HEK293 Cells
Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were detected primarily in hematopoietic cell lines and were found to be co-induced by the same activation signals. Although very low amounts of putative soluble CLEC2D protein isoforms could be produced by transfectants, CLEC2D isoforms 2 and 4 were efficiently expressed. CLEC2D uses g...

重组蛋白

CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-01231
Species: Human
Expression System: HEK293 Cells
CLEC2D Protein, Human, Recombinant (hFc & Avi)
Cat.No: TMPK-01230
Species: Human
Expression System: HEK293 Cells
CLEC2D Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01252
Species: Mouse
Expression System: HEK293 Cells
Myocilin Protein, Human, Recombinant (His)
Cat.No: TMPY-02248
Species: Human
Expression System: HEK293 Cells
Myocilin Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02792
Species: Mouse
Expression System: E. coli
Myocilin Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02793
Species: Mouse
Expression System: Baculovirus Insect Cells
CLEC2D Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-04040
Species: Rat
Expression System: HEK293 Cells
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