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Search Results for " mrs "

Targets Recommended: Adenosine Receptor

72

抑制剂 & 化合物

1

天然产物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T16136	MRS-1706	Adenosine Receptor	GPCR/G Protein; Neuroscience
	MRS-1706 是一种选择性A2B 腺苷受体的反向激动剂，对人 A2B、A2A、A1和 A3受体的Ki 值分别为 1.39、112、157 和 230 nM。
T6172	MRS 2578	Apoptosis; P2Y Receptor	Apoptosis; GPCR/G Protein; Neuroscience
	MRS 2578 是一种选择性强的P2Y6 受体拮抗剂，IC50为 37 nM，对 P2Y1、P2Y2、P2Y4 和 P2Y11 受体显示出不显着的抑制作用。
T16140	MRS 1754	Adenosine Receptor	GPCR/G Protein; Neuroscience
	MRS 1754 是A2B 腺苷受体选择性拮抗剂，对人和大鼠的 A1和 A3受体的亲和力非常低。
T12107	MRS-3777 hemioxalate	Adenosine Receptor	GPCR/G Protein; Neuroscience
	MRS-3777 hemioxalate 是一种选择性腺苷 A3 受体拮抗剂，可逆转其相应激动剂的抗伤害感受作用，可用于研究炎症性疼痛。
T23016	MRS1220 MRS 1220	Adenosine Receptor	GPCR/G Protein; Neuroscience
	MRS1220 是一种高效、选择性的人 A3 腺苷受体 (hA3AR) 拮抗剂，Ki 为 0.59 nM，可用于中枢神经系统疾病的研究。MRS1220 在体内还减少了胶质母细胞瘤的肿瘤大小和血管形成。
T28096	MRS 4062 triethylammonium salt MRS-4062,MRS4062,MRS 4062
	MRS 4062 triethylammonium salt is a selective P2Y4 receptor agonist (EC50 values are 23, 640, and 740 nM for hP2Y4, hP2Y2 and hP2Y6 respectively).
T37129	MRS 2905
	Potent and selective P2Y14 receptor agonist (EC50 = 0.92 nM). Exhibits >2000-fold selectivity over P2Y6. Das et al (2010) Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups J.Med.Chem. 53 471 PMID:19902968 \|Lazarowski et al (2015) UDP-sugars as extracellular signaling molecules: cellular and physiologic consequences of P2Y14 receptor activation. Mol.Pharmacol. 88 151 PMID:25829059
T23020	MRS 2219	Others	Others
	P2X1 receptor potentiator
T69255	MRS-2339
	MRS-2339 is a P2X receptor activator.
T16135	MRS 1523	Others	Others
	MRS 1523 can exert an antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons. MRS 1523 is an effective and selective adenosine A3 receptor antagonist Ki: 18.9 nM and 113 n
T23019	MRS 2211	Others	Others
	P2Y13 receptor antagonist
T23017	MRS 1334	Others	Others
	antagonist for the human adenosine A3 receptor
T23024	MRS 2690	Others	Others
	P2Y14 receptor agonist
T16134	MRS-1191	Others	Others
	MRS-1191 is an effective and selective A3 adenosine receptor antagonist (KB: 92 nM, a Ki: 31.4 nM for human A3 receptor and an IC50: 120 nM for CHO cells).
T23022	MRS 2365	Others	Others
	Highly potent, selective P2Y1 receptor agonist
T25837	MRS-1477
	MRS-1477 is used as a TRPV1 positive allosteric modulator (PAM).
T23026	MRS 2768 tetrasodium salt	Others	Others
	MRS 2768 tetrasodium salt is a P2Y2 agonist.
T23025	MRS 2693 trisodium salt	Others	Others
	MRS 2693 trisodium salt is a P2Y6 agonist.
T12108	MRS1845	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).
TP2271	MRS 2957 triethylammonium salt	Others	Others
	MRS 2957 triethylammonium salt is a P2Y6 agonist.
T33507	MRS923 MRS 923,MRS-923
	MRS923 is a bioactive chemical.
T33504	MRS1486 MRS 1486,MRS-1486
	MRS1486 is a bioactive chemical.
T33502	MRS1132 MRS 1132,MRS-1132
	MRS1132 is a bioactive chemical.
T28106	MRS5698 MRS 5698,MRS-5698
	MRS5698 is a high affinity and selective agonist of A3 adenosine receptor (Ki ~ 3 nM) protects against chronic neuropathic pain. MRS5698 displays >1000-fold selectivity over A1 and A2A adenosine receptors
T33496	MRS1062 MRS-1062,MRS 1062
	MRS1062 is a bioactive chemical.
T28097	MRS1067 MRS 1067,MRS-1067
	MRS1067 is an antagonist of A3 adenosine receptor.
T28101	MRS2496 MRS 2496,MRS-2496
	MRS2496 is a P2Y(1) receptor antagonist.
T33500	MRS1086 MRS-1086,MRS 1086
	MRS1086 is a bioactive chemical.
T33499	MRS1084 MRS 1084,MRS-1084
	MRS1084 is a bioactive chemical.
T33495	MRS1042 MRS-1042,MRS 1042
	MRS1042 is a bioactive chemical.
T33498	MRS1066 MRS 1066,MRS-1066
	MRS1066 is a bioactive chemical.
T28098	MRS1097 MRS-1097,MRS 1097
	MRS1097 is a selective antagonist A3 adenosine receptor.
T24499	MRS4478 MRS-4478,MRS 4478
	MRS4478 is an effective inhibitor of the P2Y14 Receptor.
T33505	MRS1505 MRS-1505,MRS 1505
	MRS1505 is a bioactive chemical.
T28099	MRS2179 MRS 2179,MRS-2179
	MRS2179 is a competitive P2Y1 receptor antagonist (Kb = 100 nM) with no appreciable activity at P2Y2, P2Y4, or P2Y6 at concentrations up to 30 µM, or at P2Y12 and P2Y13. It inhibits ADP-induced platelet shape change and aggregation (pA2 = 6.55) in vitro a
T33497	MRS1065 MRS 1065,MRS-1065
	MRS1065 is a bioactive chemical.
T28105	MRS3558 MRS-3558,MRS 3558
	MRS3558 is an agonist of A3 adenosine receptors.
T33503	MRS1476 MRS-1476,MRS 1476
	MRS1476 is a bioactive chemical.
T24498	MRS4458 MRS 4458,MRS-4458
	MRS4458 is an effective inhibitor of the P2Y14 Receptor.
T23021	MRS2279 MRS 2279	Others	Others
	Selective, high affinity competitive antagonist of the P2Y1 receptor
T33501	MRS1093 MRS-1093,MRS 1093
	MRS1093 is a bioactive chemical.
T28100	MRS2298 MRS-2298,MRS 2298
	MRS2298, a potent antagonists of the P2Y 1 receptor, has antiaggregatory activity in human platelets.
T28103	MRS2603 MRS-2603,MRS 2603
	MRS2603 is an antagonist of P2Y1 and P2Y13 receptors in 1321N1 human astrocytoma cells.
T33506	MRS2220 MRS 2220,MRS-2220
	MRS2220 is a selective enhancer of the ATP effects at fast desensitizing P2X (P2X1 and P2X3) receptors.
T28102	MRS2567 MRS-2567,MRS 2567
	MRS2567 is a potent P2Y6 nucleotide receptors antagonists.
T33494	MRS1041 MRS-1041,MRS 1041
	MRS1041 is a bioactive chemical.
T24497	MRS2500 MRS-2500,MRS 2500
	MRS2500 is a highly potent and selective platelet P2Y1 receptor antagonist.
T28104	MRS2802 GTPL-5909,GTPL 5909,MRS-2802,GTPL5909,MRS 2802
	MRS2802 is a P2Y14 receptor agonist, its EC50 value for P2Y14 receptor is 63 nM.
T68827	MRS2690
	MRS2690 is a potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.
T23023	MRS2500 tetraammonium MRS 2500 tetraammonium salt	Others	Others
	Highly potent and selective antagonist of the platelet P2Y1 receptor

化合物

Cat.No: T16136

Target: Adenosine Receptor

Cat.No: T6172

Target: Apoptosis, P2Y Receptor

Cat.No: T16140

Target: Adenosine Receptor

MRS-3777 hemioxalate

Cat.No: T12107

Target: Adenosine Receptor

Cat.No: T23016

Synonym: MRS 1220

Target: Adenosine Receptor

MRS 4062 triethylammonium salt

Cat.No: T28096

Synonym: MRS-4062,MRS4062,MRS 4062

Cat.No: T37129

Cat.No: T23020

Target: Others

Cat.No: T69255

Cat.No: T16135

Target: Others

Cat.No: T23019

Target: Others

Cat.No: T23017

Target: Others

Cat.No: T23024

Target: Others

Cat.No: T16134

Target: Others

Cat.No: T23022

Target: Others

Cat.No: T25837

MRS 2768 tetrasodium salt

Cat.No: T23026

Target: Others

MRS 2693 trisodium salt

Cat.No: T23025

Target: Others

Cat.No: T12108

Target: Calcium Channel

MRS 2957 triethylammonium salt

Cat.No: TP2271

Target: Others

Cat.No: T33507

Synonym: MRS 923,MRS-923

Cat.No: T33504

Synonym: MRS 1486,MRS-1486

Cat.No: T33502

Synonym: MRS 1132,MRS-1132

Cat.No: T28106

Synonym: MRS 5698,MRS-5698

Cat.No: T33496

Synonym: MRS-1062,MRS 1062

Cat.No: T28097

Synonym: MRS 1067,MRS-1067

Cat.No: T28101

Synonym: MRS 2496,MRS-2496

Cat.No: T33500

Synonym: MRS-1086,MRS 1086

Cat.No: T33499

Synonym: MRS 1084,MRS-1084

Cat.No: T33495

Synonym: MRS-1042,MRS 1042

Cat.No: T33498

Synonym: MRS 1066,MRS-1066

Cat.No: T28098

Synonym: MRS-1097,MRS 1097

Cat.No: T24499

Synonym: MRS-4478,MRS 4478

Cat.No: T33505

Synonym: MRS-1505,MRS 1505

Cat.No: T28099

Synonym: MRS 2179,MRS-2179

Cat.No: T33497

Synonym: MRS 1065,MRS-1065

Cat.No: T28105

Synonym: MRS-3558,MRS 3558

Cat.No: T33503

Synonym: MRS-1476,MRS 1476

Cat.No: T24498

Synonym: MRS 4458,MRS-4458

Cat.No: T23021

Synonym: MRS 2279

Target: Others

Cat.No: T33501

Synonym: MRS-1093,MRS 1093

Cat.No: T28100

Synonym: MRS-2298,MRS 2298

Cat.No: T28103

Synonym: MRS-2603,MRS 2603

Cat.No: T33506

Synonym: MRS 2220,MRS-2220

Cat.No: T28102

Synonym: MRS-2567,MRS 2567

Cat.No: T33494

Synonym: MRS-1041,MRS 1041

Cat.No: T24497

Synonym: MRS-2500,MRS 2500

Cat.No: T28104

Synonym: GTPL-5909,GTPL 5909,MRS-2802,GTPL5909,MRS 2802

Cat.No: T68827

MRS2500 tetraammonium

Cat.No: T23023

Synonym: MRS 2500 tetraammonium salt

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T33508	MRS928 3,5,7-Trimethoxyflavone,MRS-928,MRS 928	Others	Others
	MRS928 (3,5,7-Trimethoxyflavone) 是一种生物活性化学品。它具有作为植物代谢物的作用。它来自高良姜素。

天然产物

Cat.No: T33508

Synonym: 3,5,7-Trimethoxyflavone,MRS-928,MRS 928

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00528	CD204/MSR1 Protein, Mouse, Recombinant (His) MSR,Scara1,macrophage scavenger receptor 1,MSR-A,Scvr,MR...	Mouse	HEK293 Cells
	CD204/MSR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is AAH03814.1.
TMPH-02503	DEFA1 Protein, Mouse, Recombinant (GST & His) HP-1,HNP-1,Defensin, alpha 1,DEFA1,DEFA2,MRS,Neutro...	Mouse	E. coli
	Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 34.1 kDa and the accession number is P11477.
TMPH-01772	DEFA1 Protein, Human, Recombinant (GST) MRS,HP1,HP-1,DEFA1,DEF1,Defensin, alpha 1,Neutrophi...	Human	E. coli
	Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665.
TMPH-03529	Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His) CHIPS,Chemotaxis inhibitory protein,chp	Staphylococcus aureus	P. pastoris (Yeast)
	Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Re...
TMPH-03532	ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO) Clumping factor B,clfB,Fibrinogen receptor B,Fibrinogen-bind...	Staphylococcus aureus	E. coli
	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps. ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 69.8 kDa and the accession number is Q6GDH2.

重组蛋白

CD204/MSR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00528

Species: Mouse

Expression System: HEK293 Cells

DEFA1 Protein, Mouse, Recombinant (GST & His)

Cat.No: TMPH-02503

Species: Mouse

Expression System: E. coli

DEFA1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01772

Species: Human

Expression System: E. coli

Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)

Cat.No: TMPH-03529

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO)

Cat.No: TMPH-03532

Species: Staphylococcus aureus

Expression System: E. coli

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