9
4
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22864 |
Immethridine dihydrobromide
|
Others | Others |
Immethridine dihydrobromide is a histamine H3 receptor agonist. | |||
T6801 |
CeMMEC13
|
Carboxypeptidase; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Proteases/Proteasome |
CeMMEC13 是一种异喹啉酮,可选择性抑制 TAF1 的第二个溴结构域,IC50为 2.1 μM。 | |||
T4345 |
CeMMEC1
CeMMEC1 HCl |
Epigenetic Reader Domain; Carboxypeptidase; DNA/RNA Synthesis | Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome |
CeMMEC1 是一种 BRD4 抑制剂,对 TAF1 有很好的亲和力,IC50为0.9 μM。 | |||
T22863 |
Immepip dihydrobromide
|
Others | Others |
Immepip dihydrobromide is a histamine H3 receptor agonist. | |||
T73408 | Immepip | ||
Immepip 是一种 H3激动剂。Immepip 可以减少皮质组胺的释放。Immepip 可用于神经系统疾病的研究。 | |||
T77799 |
CeMMEC1 HCl
|
||
CeMMEC1是一种衍生自N-methylisoquinolinone的化合物,具有抑制TAF1第二溴结构域的功能。 | |||
T26977 |
CeMMEC2
CeMMEC-2,CeMMEC 2 |
||
CeMMEC2, a novel inhibitor of BRD4, binds both the first and the second bromodomain of BRD4. | |||
T32019 |
Guanyl-damme
Guanyl damme |
||
Guanyl-damme is an analog of stable met-enkephalin. | |||
T16467 | Pentaethylene glycol monomethyl ether | Others | Others |
Pentaethylene glycol monomethyl ether (PEG-MME) is a PEG-based PROTAC linker, which is employed for the synthesis of PROTACs[1]. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7682 |
Asymmetric dimethylarginine
|
Endogenous Metabolite; NO Synthase; NOD | Immunology/Inflammation; Metabolism; NF-κB |
Asymmetric dimethylarginine 是内源性一氧化氮合成酶抑制剂,可以作为内皮功能障碍的标志。 | |||
T73068 |
Mammea A/BA
|
||
Mammea A/BA 对克氏锥虫 (T. cruzi) 显示出有效抗性。通过诱导线粒体功能障碍、产生活性氧 (ROS)、DNA 片段化以及增加酸性液泡数量,Mammea A/BA 触发细胞死亡机制,包括细胞凋亡 (apoptosis)、细胞自噬 (autophagy) 和细胞坏死,对于南美锥虫病的研究具有潜在应用价值。 | |||
T33171 |
Mammeisin
|
||
Mammeisin is a constituent of Mammea americana. | |||
T38331 |
Commendamide
|
||
Commendamide is a natural bacterial product that was discovered in a screen for commensal bacteria effector genes (Cbegs). Cbeg12 is a bacterial effector gene that encodes for its production. Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM. |