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Search Results for " isatin "

14

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T60272	Isatin-β-thiosemicarbazone IBT	HSV	Microbiology/Virology
	Isatin-β-thiosemicarbazone 是一种有效的单纯疱疹病毒 (HSV) 抑制剂。Isatin-β-thiosemicarbazone 在对 HSV-1 和 HSV-2 都具有抑制作用，表现出抗病毒活性。Isatin-β-thiosemicarbazone 是一种有效的抗痘病毒剂 (anti-poxvirus）可用用于治疗猴痘病毒、正痘病毒和牛痘病毒。
T21219	Isatin-O Isatin-3-oxime
	Isatin-O acts as a neutral BBB crossing reactivator for acetylcholinesterase inhibited by paraoxon and is also an anticonvulsant.
T71987	5-hydroxy Isatin
	5-hydroxy Isatin is an inhibitor of monoamine oxidase A and also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.
T71349	GRC-6211
	GRC-6211 is an oral specific TRPV1 antagonist which decreases bladder overactivity and noxious bladder input in cystitis animal models.
Fr13755	5-Fluoroisatin 5-氟靛红
	Compound Fr13755 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 Fr13755，CAS号为 443-69-6。
T77568	6,7-dimethylisatin 6,7-dimethyl-1H-indole-2,3-dione	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) 对 hGAT3 的抑制效力为108μM，对 hBGT1，hGAT2 也具有抑制作用。
T7311	Oxyphenisatin acetate	Autophagy	Autophagy
	Oxyphenisatin acetate 是oxyphenisatin 的前体药物，可抑制乳腺癌细胞系 MCF7、T47D、HS578T 和 MDA-MB-468 的生长。
T7071	Oxyphenisatine Oxyphenisatin
	Oxyphenisatine (Oxyphenisatin) 是与相关的bisacodyl, picosulfate 钠和酚酞，是具有抗癌活性的的氧联苯沙星的前体药，常作为泻药使用，长期使用会造成肝损伤。
T124719	Anisatin
	Anisatin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124719。
T34748	Sulisatin disodium salt DAN603,Sulisatin sodium,DAN-603,DAN 603,Laxitex
	Sulisatin disodium salt is a laxative.
T26237	Sulisatin DAN 603,Laxitex,DAN603,Sulisatinum,DAN-603
	Sulisatin 是一种泻药。它在大肠中被肠道菌群水解为其二苯衍生物BHMI，BHMI 负责药物的通便活性。
T33704	N-Methylisatin beta-4',4'-diethylthiosemicarbazone
	N-Methylisatin beta-4',4'-diethylthiosemicarbazone is a bioactive chemical.
T36189	CAY10406
	CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. The non-trifluoromethyl compound exhibits Ki values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are 'effector caspases' that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently a...
T72260	Antileishmanial agent-13
	Antileishmanial agent-13 是一种喹啉-靛蓝杂交物，可作为抗利什曼病试剂，抑制L. MajorLeishmania 株系。Antileishmanial agent-13 通过抗叶酸机制获得其抗利什曼病活性。Antileishmanial agent-13 对前鞭毛体和无鞭毛体均具有较强的抑制作用，IC50分别为 0.604 μM 和 0.508 μM。

化合物

Isatin-β-thiosemicarbazone

Cat.No: T60272

Synonym: IBT

Target: HSV

Cat.No: T21219

Synonym: Isatin-3-oxime

5-hydroxy Isatin

Cat.No: T71987

Cat.No: T71349

Cat.No: Fr13755

Synonym: 5-氟靛红

6,7-dimethylisatin

Cat.No: T77568

Synonym: 6,7-dimethyl-1H-indole-2,3-dione

Target: GABA Receptor

Oxyphenisatin acetate

Cat.No: T7311

Target: Autophagy

Cat.No: T7071

Synonym: Oxyphenisatin

Cat.No: T124719

Sulisatin disodium salt

Cat.No: T34748

Synonym: DAN603,Sulisatin sodium,DAN-603,DAN 603,Laxitex

Cat.No: T26237

Synonym: DAN 603,Laxitex,DAN603,Sulisatinum,DAN-603

N-Methylisatin beta-4',4'-diethylthiosemicarbazone

Cat.No: T33704

Cat.No: T36189

Antileishmanial agent-13

Cat.No: T72260

Cat. No.	Product Name	Target	Signaling Pathways
T6862	Isatin Pseudoisatin,板蓝根,Indoline-2,3-dione,2,3-Indolinedione	Apoptosis; MAO; Monoamine Oxidase	Apoptosis; Metabolism; Neuroscience
	Isatin (2,3-Indolinedione) 是一种单胺氧化酶抑制剂，IC50为3 μM。它也可作为心钠肽刺激和一氧化氮刺激的鸟苷酸环化酶活性的拮抗剂，显示对血清素系统有影响。
TN7147	6-Hydroxyisatin 6-Hydroxy-1H-indole-2,3-dione,ZINC14455608,6-hydroxyindoline-2,3-dione,6-羟基靛红,6-hydroxy-2,3-dihydro-1H-indole-2,3-dione	Others	Others
	6-Hydroxyisatin (ZINC14455608) 是一种海洋来源的天然产物，存在于 Streptomyces sp.。
T83419	1α-Hydroxy-3-deoxypseudoanisatin
	1α-Hydroxy-3-deoxypseudoanisatin (Iso-γ-fagarine) 是倍半萜类化合物，可从八角(Illicium merrillianum)果皮中分离。
TN4800	Pisatin	NADPH-oxidase; P450	Immunology/Inflammation; Metabolism
	Pisatin is an isoflavonoid phytoalexin synthesized by pea (Pisum sativum L.).

天然产物

Cat.No: T6862

Synonym: Pseudoisatin,板蓝根,Indoline-2,3-dione,2,3-Indolinedione

Target: Apoptosis, MAO, Monoamine Oxidase

6-Hydroxyisatin

Cat.No: TN7147

Synonym: 6-Hydroxy-1H-indole-2,3-dione,ZINC14455608,6-hydroxyindoline-2,3-dione,6-羟基靛红,6-hydroxy-2,3-dihydro-1H-indole-2,3-dione

Target: Others

1α-Hydroxy-3-deoxypseudoanisatin

Cat.No: T83419

Cat.No: TN4800

Target: NADPH-oxidase, P450

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