Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0825 |
Ebselen
SPI-1005,PZ-51,依布硒,CCG-39161 |
Phosphatase; Virus Protease; Calcium Channel; COX; HIV Protease | Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome |
Ebselen (CCG-39161) 是一种谷胱甘肽过氧化物酶模拟物,是电压依赖性钙通道阻断剂。它抑制Mpro 和COVID-19病毒,是HIV-1衣壳 CTD 二聚化的抑制剂,具有抗炎、抗癌和抗氧化活性。 | |||
T15685 | L-690330 | Others | Others |
L-690330 is a competitive inositol monophosphatase inhibitor (Kis: 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase). L-690330 shows 10-fold more sensitive than a mouse and rat IMPase. | |||
T60820 | L-690330 hydrate | ||
L-690330 hydrate 是肌醇单磷酸酶(IMPase)的竞争性抑制剂。L-690330 hydrate 对人和牛额叶皮质 IMPase 的为 Ki 值为 0.30 μM 和 0.42 μM。L-690330 hydrate 对重组人和牛 IMPase 的 Ki 值为 0.27 μM 和 0.19 μM。 | |||
T11797 |
L-690488
|
Others | Others |
L-690488 has more effective cell penetration than L-690330. L-690488 is a prodrug of L-690330 and is a selective inositol monophosphatase (IMPase) inhibitor. |