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Search Results for " il-13 "
Targets Recommended: IL Receptor

27

抑制剂 & 化合物

2

天然产物

44

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Cat. No. Product Name Target Signaling Pathways
T76704 Tralokinumab

CAT-354,LP 0162

IL Receptor Immunology/Inflammation
Tralokinumab 是一种全人源 IgG4 单克隆抗体,对单独的 IL-13 亲和力较高。Tralokinumab 具有潜在的抗炎活性,可预防IL-13与受体相互作用和随后的下游信号传导,可用于研究特应性皮炎 (AD) 。
T76773 Rolinsatamab

IL Receptor Immunology/Inflammation
Rolinsatamab 是一种完全人源化的选择性单克隆抗体,是一种有效的 IL-4 和 IL-13 双重抑制剂。Rolinsatamab 嵌合抗原受体序列 T 细胞。Rolinsatamab 可用于预防和治疗免疫疾病。
T76896 Abrezekimab

UCB4144,VR 942

IL Receptor Immunology/Inflammation
Abrezekimab (VR 942) 由 CDP7766、亮氨酸和海藻糖组成。Abrezekimab 是一种人源化靶向人 IL-13 的抗体。Abrezekimab 制止与 IL-13Rα1 亚基的结合。Abrezekimab 可用于研究哮喘和肺部疾病相关的生物障碍。
T36527 IL-4-inhibitor-1

IL Receptor Immunology/Inflammation
IL-4-inhibitor-1 是 IL-4 的抑制剂 (EC50 = 1.81 µM)。
T13666 Dupilumab

REGN-668,SAR-231893

IL Receptor Immunology/Inflammation
Dupilumab (REGN-668) 是一种用于AD 的全身免疫调节剂。Dupilumab 是一种针对白细胞介素-4受体α亚基的完全人类单克隆抗体,可抑制IL-4和IL-13下游信号传导,具有改善特应性皮炎的作用。
T5416 T-5224

MMP Proteases/Proteasome
T-5224 是选择性的转录因子c-Fos/activator protein (AP)-1抑制剂,具有抗炎作用,能够特异性抑制 c-Fos/c-Jun 的 DNA 结合活性,但对其他转录因子的结合活性无影响。它抑制 IL-1β 诱导的 Mmp-3、Mmp-13、Adamts-5 转录上调。
T80610 Romilkimab

SAR156597

Romilkimab (SAR156597),一种特异性结合IL-4与IL-13的嵌合人源化IG抗体。
T76942 Cendakimab

Cendakimab (RPC4046; ABT 308; CC-93538)为一种选择性人源化IL-13重组单克隆抗体,对人野生型和变异型IL-13显示出高亲和力和效力。该抗体通过阻断IL-13IL-13Rα1及IL-13Rα2的结合,抑制作用力分别在ELISA测定中的IC50值为352 pM与631 pM。Cendakimab还能识别野生型和R110Q多态变体IL-13,其结合亲和力分别为52 pM与50 pM。其显示出针对IL-13相关过敏/炎症性疾病的潜在治疗作用,如哮喘和嗜酸性粒细胞性食管炎。
T9901A-011 Lunsekimig

SAR443765

Lunsekimig (SAR443765) 是一种 IL-13/TSLP 双抗,将靶向 IL-13 和靶向 TSLP 的重链可变区 (VHH) 连接在一起的纳米抗体,可用于哮喘研究。
T70001 Pyrazinib

Pyrazinib is a novel inhibitor of angiogenesis and metabolism of oesophageal adenocarcinoma (oac) radioresistance, significantly inhibiting the secretion of il-6, il-4, il-8 and il-13 cytokines from in oac radioresistant cells
T76686 Lebrikizumab

Lebrikizumab 为 IgG4 类型的人源化单克隆抗体,具有特异性地结合并抑制白介素 13 (interleukin-13; IL-13) 功能的能力,主要用于哮喘相关研究。
T81098 Stapokibart

CM310

Stapokibart (CM310) 是一款针对IL-4Rα的人源化单克隆抗体,有效抑制IL-4及IL-13与该受体亚基的结合。该药物对人类、食蟹猴和大鼠的IL-4Rα都有作用。
T73018 NLRP3-IN-13

NLRP3-IN-13 是一种有效的选择性NLRP3抑制剂 (IC50: 2.1 μM)。NLRP3-IN-13 抑制NLRP3和 NLRC4 炎性体,并抑制NLRP3介导的 IL-1β 产生。NLRP3-IN-13 还抑制NLRP3ATPase 活性。NLRP3-IN-13可用于神经炎症疾病的研究。
T60921 PF-07038124

PF-07038124是 PDE4 的抑制剂。PF-07038124 对 PDE4B2 的 IC50值为0.5 nM。PF-07038124 对IFNγ、IL-4 和 IL-13具有抑制活性,IC50值分别为 1.06、4.1 和125 nM。
T81314 Rademikibart

CBP-201

Rademikibart (CBP-201) 是一款针对IL-4Rα的人源化单克隆抗体,其与人IL-4Rα的结合亲和力KD值为20.7 pM。该抗体不与其他物种的IL-4Rα发生交互作用。Rademikibart 能够抑制PBMC中IL-4及IL-13介导的STAT6信号通路、TF-1细胞的增殖以及TARC的产生,显示出其在中到重度Th2型炎症性疾病研究中的应用潜力。
T76906 Anrukinzumab

Anrukinzumab (IMA-638),一种针对人IL-13的人源化单克隆抗体,展示了在食蟹猕猴肺部炎症模型中显著的疗效。Anrukinzumab 目前被用于溃疡性结肠炎(UC)和哮喘的研究中。
T80599 Dectrekumab

QAX576

Dectrekumab (QAX576) 是针对IL-13的人源化单克隆抗体。它能显著降低嗜酸性粒细胞性食管炎 (EoE) 患者上皮内的嗜酸性粒细胞数量,并改善食管疾病相关的转录失调情况,适用于免疫炎症研究。
T36623 Antileukinate

Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 μM), prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. At 53 mg/kg, antileukinate has been shown to protect mice against acute pancreatitis and associated lung injury.
T71143 Ambroxol-d5

Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous part...
T37564 C4 Ceramide (d18:1/4:0)

C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)

C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. [1] C4 Ceramide is cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively). [2] C4 Ceramide also increases maturation and stability of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing...
T36998 7β,27-dihydroxy Cholesterol

7β,27-DHC,7β,27-dihydroxy Cholesterol

7β,27-dihydroxy Cholesterol is an oxysterol and agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and RORγt. [1] It activates RORγ- or RORγt-dependent signaling with EC50 values of 691 and 1,045 nM, respectively, in reporter assays using HEK293T cells expressing the recombinant human receptors. 7β,27-dihydroxy Cholesterol is selective for RORγ and RORγt over a panel of eight additional nuclear receptors at 30 &#181M. It increases IL-17A production in Th17-polarized isolated hum...
T36320 C6 L-threo Ceramide (d18:1/6:0)

C6 L-threo Ceramide (d18:1/6:0)

C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 L-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 L-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.
T71933 GNE-3500

GNE-3500 is a Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C (RORc or RORγ) Inverse Agonist. Retinoic acid receptor-related orphan receptor C (RORc, RORγ, or NR1F3) is a nuclear receptor that plays a major role in the production of interleukin (IL)-17. Considerable efforts have been directed toward the discovery of selective RORc inverse agonists as potential treatments of inflammatory diseases such as psoriasis and rheumatoid arthritis. GNE-3500 poss...
T37565 C6 D-threo Ceramide (d18:1/6:0)

C6 D-threo Ceramide (d18:1/6:0)

C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater...
T35927 C2 L-threo Ceramide (d18:1/2:0)

C2 L-threo Ceramide (d18:1/2:0)

C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1...
T35864 T-5342126

T-5342126 is a toll-like receptor 4 (TLR4) antagonist.1It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50= 27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood (IC50s = 110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-depen...
T35406 α-MSH TFA

α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.1It is an agonist of melanocortin receptor 3 (MC3R) and MC4R that induces cAMP production in Hepa cells expressing the human receptors (EC50s = 0.16 and 56 nM, respectively).2α-MSH (100 pM) reducesS. aureuscolony formation andC. albicansgerm tube fo...

化合物

Tralokinumab
Cat.No: T76704
Synonym: CAT-354,LP 0162
Target: IL Receptor
Rolinsatamab
Cat.No: T76773
Synonym:
Target: IL Receptor
Abrezekimab
Cat.No: T76896
Synonym: UCB4144,VR 942
Target: IL Receptor
IL-4-inhibitor-1
Cat.No: T36527
Synonym:
Target: IL Receptor
Dupilumab
Cat.No: T13666
Synonym: REGN-668,SAR-231893
Target: IL Receptor
T-5224
Cat.No: T5416
Synonym:
Target: MMP
Romilkimab
Cat.No: T80610
Synonym: SAR156597
Target:
Cendakimab
Cat.No: T76942
Synonym:
Target:
Lunsekimig
Cat.No: T9901A-011
Synonym: SAR443765
Target:
Pyrazinib
Cat.No: T70001
Synonym:
Target:
Lebrikizumab
Cat.No: T76686
Synonym:
Target:
Stapokibart
Cat.No: T81098
Synonym: CM310
Target:
NLRP3-IN-13
Cat.No: T73018
Synonym:
Target:
PF-07038124
Cat.No: T60921
Synonym:
Target:
Rademikibart
Cat.No: T81314
Synonym: CBP-201
Target:
Anrukinzumab
Cat.No: T76906
Synonym:
Target:
Dectrekumab
Cat.No: T80599
Synonym: QAX576
Target:
Antileukinate
Cat.No: T36623
Synonym:
Target:
Ambroxol-d5
Cat.No: T71143
Synonym:
Target:
C4 Ceramide (d18:1/4:0)
Cat.No: T37564
Synonym: C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)
Target:
7β,27-dihydroxy Cholesterol
Cat.No: T36998
Synonym: 7β,27-DHC,7β,27-dihydroxy Cholesterol
Target:
C6 L-threo Ceramide (d18:1/6:0)
Cat.No: T36320
Synonym: C6 L-threo Ceramide (d18:1/6:0)
Target:
GNE-3500
Cat.No: T71933
Synonym:
Target:
C6 D-threo Ceramide (d18:1/6:0)
Cat.No: T37565
Synonym: C6 D-threo Ceramide (d18:1/6:0)
Target:
C2 L-threo Ceramide (d18:1/2:0)
Cat.No: T35927
Synonym: C2 L-threo Ceramide (d18:1/2:0)
Target:
T-5342126
Cat.No: T35864
Synonym:
Target:
α-MSH TFA
Cat.No: T35406
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN1189 13-Methylberberine chloride

13-甲基小檗碱,13-Methylberberine

Others Others
13-Methylberberine chloride 是一种黄连素类似物,可增加 IL-12 的产生,并在 LPS 激活的巨噬细胞转录后抑制 iNOS 的表达,具有抗脂肪和抗肿瘤作用。
T35741 Gliovirin

Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decrease...

天然产物

13-Methylberberine chloride
Cat.No: TN1189
Synonym: 13-甲基小檗碱,13-Methylberberine
Target: Others
Gliovirin
Cat.No: T35741
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01993 IL-13 Protein, Human, Recombinant

IL-13,P600,interleukin 13,ALRH,白介...

Human CHO Cells
IL-13 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.5 kDa and the accession number is AAK53823.1.
TMPY-03123 IL-13 Protein, Mouse, Recombinant

白细胞介素,Il-13,白介素,interleukin 13

Mouse HEK293 Cells
IL-13 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.35 kDa and the accession number is P20109.
TMPJ-00575 IL-13 Protein, Human, Recombinant (His)

Interleukin-13,IL-13,白介素,白细胞介素

Human HEK293 Cells
IL-13 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 13-30 KDa and the accession number is AAH96139.
TMPY-00840 IL-13 Protein, Human, Recombinant (hFc)

IL-13,白介素,白细胞介素,ALRH,interleukin 13

Human HEK293 Cells
IL-13 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is AAK53823.1.
TMPJ-00890 IL-13 Protein, Mouse, Recombinant (aa 26-131, His)

Interleukin-13,T-Cell Activation Protein P600,白细胞介素...

Mouse HEK293 Cells
IL-13 Protein, Mouse, Recombinant (aa 26-131, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 15-30 KDa and the accession number is P20109.
TMPJ-00889 IL-13 Protein, Mouse, Recombinant (aa 22-131, His)

T-Cell Activation Protein P600,IL-13,白细胞介素...

Mouse HEK293 Cells
IL-13 Protein, Mouse, Recombinant (aa 22-131, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 14-30 KDa and the accession number is P20109.
TMPJ-00596 IL-13 Protein, Human, Recombinant (mFc)

Interleukin-13,白介素,IL-13,白细胞介素

Human HEK293 Cells
IL-13 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 38-60 KDa and the accession number is AAK53823.
TMPY-01258 IL-13RA1 Protein, Human, Recombinant (His)

NR4,interleukin 13 receptor, alpha 1,CD213...

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-00841 IL-13RA2 Protein, Human, Recombinant (His)

CT19,interleukin 13 receptor, alpha 2,CD213

Human HEK293 Cells
IL-13RA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q14627.
TMPY-01170 IL-13RA1 Protein, Mouse, Recombinant (His)

interleukin 13 receptor, α1,CD213a1,Il...

Mouse HEK293 Cells
IL-13RA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is O09030.
TMPJ-00594 IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated

Interleukin-13,白细胞介素,IL-13,白介素

Human HEK293 Cells
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 22-35 KDa and the accession number is AAK53823.
TMPK-00617 IL-13 Protein, Human, Recombinant (His & Avi)

NC30,ALRH,IL13,MGC116786,MGC116789,P600,MG...

Human HEK293 Cells
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macro...
TMPY-00982 IL-13 Protein, Cynomolgus, Recombinant

白介素,interleukin 13,白细胞介素

Cynomolgus HEK293 Cells
IL-13 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.3 kDa and the accession number is Q0PW92.
TMPK-00244 IL-13RA2 Protein, Mouse, Recombinant (His)

IL13RA2,IL13R,IL

Mouse HEK293 Cells
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2. IL-13RA2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells...
TMPK-00243 IL-13Ra2 Protein, Human, Recombinant (hFc)

CD213a2,IL13RA2,IL13...

Human HEK293 Cells
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2. IL-13Ra2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells...
TMPK-00272 IL-13RA1 Protein, Human, Recombinant (His & Avi), Biotinylated

AI882074,IL-13 R alpha 1,IL-1...

Human HEK293 Cells
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2. IL-13RA1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HE...
TMPY-01074 IL-13RA1 Protein, Human, Recombinant (His & hFc)

NR4,CD213A1,interleukin 13 receptor, alpha...

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 65 kDa and the accession number is P78552-1.
TMPK-00273 IL-13Ra1 Protein, Human, Recombinant (hFc)

NR4,CD213A1,IL-13 R alpha 1,CT19,...

Human HEK293 Cells
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2. IL-13Ra1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells...
TMPY-00842 IL-13RA2 Protein, Human, Recombinant (His & hFc)

CT19,IL13BP,interleukin 13 recept...

Human HEK293 Cells
IL-13RA2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q14627.
TMPY-06579 IL-13RA1 Protein, Human, Recombinant(aa 1-343, His & Avi), Biotinylated

IL-13Ra,CD213A1,interleukin 1...

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant(aa 1-343, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 40.15 kDa and the accession number is NP_001551.1.
TMPY-06590 IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc)

CD213A1,interleukin 13 receptor, alpha 1,N...

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.62 kDa and the accession number is NP_001551.1.
TMPY-05123 IL-13RA1 Protein, Human, Recombinant (His), Biotinylated

CD213A1,interleukin 13 receptor, alpha 1,<...

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-05334 IL-13RA2 Protein, Human, Recombinant (His), Biotinylated

CT19,IL-13R,IL13BP,inter...

Human HEK293 Cells
IL-13RA2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q14627.
TMPY-05795 IL-13RA1 Protein, Mouse, Recombinant (mFc)

IL-13r[a],interleukin 13 receptor...

Mouse HEK293 Cells
IL-13RA1 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 62.41 kDa and the accession number is O09030.
TMPY-05432 IL-13RA1 Protein, Mouse, Recombinant (hFc)

IL-13r[a],AI882074,NR4,Il13

Mouse HEK293 Cells
IL-13RA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.8 kDa and the accession number is O09030.
TMPJ-00270 IL-13RA1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Interleukin-13 receptor subunit α-1,NR4,Interleukin...

Mouse HEK293 Cells
Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TRAF3IP1 and binds with low affinity to interleukin-13(IL3). IL-13RA1, together with IL4RA, can form a functional receptor for IL13. It also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace th...
TMPH-00493 IL-13 Protein, Canine, Recombinant (His)

Canine E. coli
IL-13 Protein, Canine, Recombinant (His) is expressed in E. coli.
TMPY-02136 IL-13 Protein, Cynomolgus, Recombinant (His)

白细胞介素,interleukin 13,白介素

Cynomolgus HEK293 Cells
IL-13 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.5 kDa and the accession number is Q0PW92.
TMPH-00551 IL-13 Protein, Equus caballus, Recombinant (His)

Horse P. pastoris (Yeast)
IL-13 Protein, Equus caballus, Recombinant (His) is expressed in Yeast.
TMPJ-01210 IL-33 Protein, Mouse, Recombinant

Interleukin-1 family member 11,白细胞介素,NF-HEV and

Mouse E. coli
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up‑regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL‑1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produ...
TMPY-06981 IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

interleukin 1 α,IL1,白介素,IL-1F1,IL...

Human E. coli
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage...
TMPJ-00387 IL-4R alpha Protein, Mouse, Recombinant (hFc)

Soluble IL-4R-alpha,Interleukin-4 receptor subunit ...

Mouse HEK293 Cells
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ...
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain)

HME,ME,MMP-12,MME,matrix metallopeptidase 12

Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ...
TMPK-00035 IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated

binetrakin,BCGF1,IL4,白介素,白细胞介素,BSF1,IL-4,M...

Human HEK293 Cells
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor.
TMPY-02790 IL-4 Protein, Canine, Recombinant

白介素,interleukin 4,白细胞介素

Canine E. coli
IL-4 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is O77762.
TMPK-00034 IL-4 Protein, Human, Recombinant (His & Avi)

IL4,B cell growth factor 1,interleukin 4,BCGF1,BSF1...

Human HEK293 Cells
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. . IL-4 Protein, Human, Recombinant (His...
TMPK-00919 IL-4 Protein, Cynomolgus, Recombinant (His)

BCGF-1,BSF-1,MGC79402,binetrakin,BCGF1,BSF1,BCDF,IL...

Cynomolgus HEK293 Cells
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. . IL-4 Protein, Cynomolgus, Recombinant...
TMPY-05353 CCL26 Protein, Human, Recombinant

MIP-4alpha,SCYA26,MIP-4a,chemokine (C-C motif) ligand 26,IMA...

Human Baculovirus Insect Cells
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3), which is also expressed by several different cell types, including basophils, dendritic cells, smooth muscle cells, epithelial cells and fibroblasts. The sequence similarity between the three eotaxins is limited (<4%), but their functional properties are very similar. Eotaxin-1 ...
TMPJ-01056 IL-18 Protein, Mouse, Recombinant (His)

Interferon γ-inducing factor,Interleukin-1 gamma,Igif,IL...

Mouse E. coli
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins...
TMPH-03267 CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)

Clm1,Cd300lf,CD300 antigen-like family member F,CLM...

Rat E. coli
Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell ...
TMPH-03116 IL-4R Protein, Pig, Recombinant (His)

Sus scrofa (Pig) E. coli
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. IL-4R Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted mo...
TMPH-03266 CHI3L1 Protein, Rat, Recombinant (His)

Chi3l1,Cartilage glycoprotein 39,CGP-39,GP-39,Chiti...

Rat E. coli
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mu...
TMPK-01373 Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc)

FINC,LETS,GFND,SMDCF,GFND2,ED-B,MSF,FNZ,FN1,FN,CIG

Human HEK293 Cells
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicte...
TMPK-01391 Fibronectin Protein, Human, Recombinant (aa 1266-1356, His)

FN1,LETS,GFND,MSF,FNZ,CIG,ED-B,FN,SMDCF,GFND2,FINC

Human HEK293 Cells
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 1266-1356, His) is expressed in HEK293 mammalian cells with C-His tag. The predicte...

重组蛋白

IL-13 Protein, Human, Recombinant
Cat.No: TMPY-01993
Species: Human
Expression System: CHO Cells
IL-13 Protein, Mouse, Recombinant
Cat.No: TMPY-03123
Species: Mouse
Expression System: HEK293 Cells
IL-13 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00575
Species: Human
Expression System: HEK293 Cells
IL-13 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00840
Species: Human
Expression System: HEK293 Cells
IL-13 Protein, Mouse, Recombinant (aa 26-131, His)
Cat.No: TMPJ-00890
Species: Mouse
Expression System: HEK293 Cells
IL-13 Protein, Mouse, Recombinant (aa 22-131, His)
Cat.No: TMPJ-00889
Species: Mouse
Expression System: HEK293 Cells
IL-13 Protein, Human, Recombinant (mFc)
Cat.No: TMPJ-00596
Species: Human
Expression System: HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01258
Species: Human
Expression System: HEK293 Cells
IL-13RA2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00841
Species: Human
Expression System: HEK293 Cells
IL-13RA1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01170
Species: Mouse
Expression System: HEK293 Cells
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00594
Species: Human
Expression System: HEK293 Cells
IL-13 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00617
Species: Human
Expression System: HEK293 Cells
IL-13 Protein, Cynomolgus, Recombinant
Cat.No: TMPY-00982
Species: Cynomolgus
Expression System: HEK293 Cells
IL-13RA2 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00244
Species: Mouse
Expression System: HEK293 Cells
IL-13Ra2 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00243
Species: Human
Expression System: HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00272
Species: Human
Expression System: HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-01074
Species: Human
Expression System: HEK293 Cells
IL-13Ra1 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00273
Species: Human
Expression System: HEK293 Cells
IL-13RA2 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00842
Species: Human
Expression System: HEK293 Cells
IL-13RA1 Protein, Human, Recombinant(aa 1-343, His & Avi), Biotinylated
Cat.No: TMPY-06579
Species: Human
Expression System: HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc)
Cat.No: TMPY-06590
Species: Human
Expression System: HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05123
Species: Human
Expression System: HEK293 Cells
IL-13RA2 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05334
Species: Human
Expression System: HEK293 Cells
IL-13RA1 Protein, Mouse, Recombinant (mFc)
Cat.No: TMPY-05795
Species: Mouse
Expression System: HEK293 Cells
IL-13RA1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05432
Species: Mouse
Expression System: HEK293 Cells
IL-13RA1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00270
Species: Mouse
Expression System: HEK293 Cells
IL-13 Protein, Canine, Recombinant (His)
Cat.No: TMPH-00493
Species: Canine
Expression System: E. coli
IL-13 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-02136
Species: Cynomolgus
Expression System: HEK293 Cells
IL-13 Protein, Equus caballus, Recombinant (His)
Cat.No: TMPH-00551
Species: Horse
Expression System: P. pastoris (Yeast)
IL-33 Protein, Mouse, Recombinant
Cat.No: TMPJ-01210
Species: Mouse
Expression System: E. coli
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
Cat.No: TMPY-06981
Species: Human
Expression System: E. coli
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00387
Species: Mouse
Expression System: HEK293 Cells
MMP-12 Protein, Human, Recombinant (catalytic domain)
Cat.No: TMPY-02869
Species: Human
Expression System: E. coli
IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00035
Species: Human
Expression System: HEK293 Cells
IL-4 Protein, Canine, Recombinant
Cat.No: TMPY-02790
Species: Canine
Expression System: E. coli
IL-4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00034
Species: Human
Expression System: HEK293 Cells
IL-4 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00919
Species: Cynomolgus
Expression System: HEK293 Cells
CCL26 Protein, Human, Recombinant
Cat.No: TMPY-05353
Species: Human
Expression System: Baculovirus Insect Cells
IL-18 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01056
Species: Mouse
Expression System: E. coli
CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03267
Species: Rat
Expression System: E. coli
IL-4R Protein, Pig, Recombinant (His)
Cat.No: TMPH-03116
Species: Sus scrofa (Pig)
Expression System: E. coli
CHI3L1 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03266
Species: Rat
Expression System: E. coli
Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc)
Cat.No: TMPK-01373
Species: Human
Expression System: HEK293 Cells
Fibronectin Protein, Human, Recombinant (aa 1266-1356, His)
Cat.No: TMPK-01391
Species: Human
Expression System: HEK293 Cells
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