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Search Results for " hx "

Targets Recommended: Retinoid Receptor

24

抑制剂 & 化合物

1

天然产物

15

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T22843	HX 531	Retinoid Receptor	Metabolism
	HX 531 是的RXR 拮抗剂 (IC50:18 nM) 。它能减少高脂饮食小鼠的骨骼肌、白色脂肪组织和肝脏中的甘油三酯含量。
T32107	HX-603 HX 603
	HX-603 is a selectivity agonist of RXR that inhibits the activation of RAR-RXR heterodimers as well as RXR homodimers.
T21369	Mecillinam Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX	Antibacterial	Microbiology/Virology
	Mecillinam (Hexacillin) 是一种有抗革兰氏阴性菌活性的 β 内酰胺类广谱抗生素。
T70237	HX-600
	HX-600 is a synthetic agonist for the RXR-Nurr1 heterodimer complex. HX-600 prevents ischemia-induced neuronal damage.
T22844	HX 630	Others	Others
	RXR agonist
T3647	HTHQ HX 1171,HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone),1-O-hexyl-2,3,5-trimethylhydroquinone	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	HTHQ (HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone)) 是一种强力的亲脂性酚类抗氧化剂。它通过与活性氧直接反应，清除 ROS，从而形成更稳定的自由基，具有很强的抗氧化活性。
T25510	HX1 HX 1,HX-1
	HX1 is a potent reversible myeloperoxidase (MPO) inhibitor.
T80984	Tilogotamab GEN-1029,HexaBody-DR5/DR5,Hx-DR5-01/05
	Tilogotamab (GEN-1029)为针对5型死亡受体（DR5）上两个独立表位的激动性六聚体形成增强混合物，能特异性结合并激活DR5，适用于多发性骨髓瘤（MM）研究。
T70236	Isonitrosoacetone
	Isonitrosoacetone is an acetylcholinesterase reactivator.
T75015	HX103
	HX103 是一种基于表皮生长因子受体 (EGFR)-酪氨酸激酶抑制剂 (TKI) 的荧光探针。HX103 抑制 EGFR19 del、EGFRL858R、EGFRwild type 和 EGFRT790M，IC50分别为1.3、1.5、4.0 和 977 nM。HX103 可用于定量活性 EGFR，可用于 NSCLC 的研究。
T82568	DHX9-IN-2	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	DHX9-IN-2 是一种针对ATP依赖型RNA解螺旋酶A(DHX9)的抑制剂，具有抗癌和抗肿瘤活性，可用于研究癌症。
T32108	HXJ42 HXJ-42,HXJ 42	Others	Others
	HXJ42 是一种 PP1 类似物，可选择性地有效作用于野生型 ZAP-70 (AS)。
T13613	ChX710	STING	Immunology/Inflammation
	ChX710可以引发 I 型干扰素对细胞溶质 DNA 的反应，其特异性细胞干扰素刺激基因 (ISG) 诱导 ISRE 启动子序列和干扰素调节因子 (IRF) 3 的磷酸化。
T76465	Biotinyl-Ahx-Amyloid β-Protein (1-42) (ammonium)
	Biotinyl-Ahx-Amyloid β-Protein (1-42) ammonium 为N-末端接有生物素的 Amyloid β-Protein (1-42)，主要存在于阿尔茨海默病患者血管与脑组织中的淀粉样沉积物中。
T80120	FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578)	HSV	Microbiology/Virology
	FITC-εAhx-HHV-2 EnvelopeGlycoproteinG (561-578) 是带有FITC标记的糖蛋白G (gG-2)的免疫原性片段，涵盖了其氨基酸序列的561至578位点。此段具有广泛的与单纯疱疹病毒2型(HSV-2)血清呈现交叉反应的特性。
T41062	HXR9
	HXR9 is a cell-permeable peptide that acts as a competitive antagonist of the HOX/PBX interaction. It effectively inhibits the binding between HOX proteins and the transcription factor PBX, specifically in paralogue groups 1 to 8. HXR9 selectively impairs cell proliferation and induces apoptosis in cells with a high expression of the HOXA/PBX3 genes, for instance, MLL-rearranged leukemic cells.
T80127	FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro	Integrin	Cytoskeletal Signaling
	FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro为FITC标记的GRGDSP，后者为整联蛋白(integrin)抑制剂，能阻止肿瘤细胞与血管内皮细胞粘附，进而抑制肿瘤转移。
T82569	DHX9-IN-1
	DHX9-IN-1，作为ATP依赖性RNA解螺旋酶A (DHX9) 的抑制剂，表现出9.45 nM的IC50值，并具有抗肿瘤活性。
T74097	THX-B
	THX-B为一高效非多肽类p75NTR（神经营养蛋白受体p75）拮抗剂，适用于糖尿病、肾病、神经退行性及炎症性疾病研究。
T17793	DBCO-PEG4-Ahx-DM1	Others	Others
	DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate that combines the microtubulin inhibitor DM1 (mertansine), which is an antibody-conjugatable maytansinoid designed to reduce systemic toxicity and improve tumor-specific delivery, with the linker DBCO-PEG4-Ahx, for the development of antibody drug conjugates (ADCs).
T65558	Boc-Asp(OcHx)-OH
	Boc-Asp(OcHx)-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65558，CAS号为 73821-95-1。
T76213	HXR9 hydrochloride
	HXR9 hydrochloride 是一种针对 HOX/PBX 相互作用的细胞渗透性肽类竞争性拮抗剂。它通过阻碍 HOX 蛋白与 PBX，一个与旁系同源基因组 1 至 8 结合的第二转录因子，之间的相互作用来发挥作用。特别地，HXR9 hydrochloride 能够选择性抑制细胞增殖，并在表达 HOXA/PBX3 基因高水平的细胞中，如 MLL 重排的白血病细胞，促进细胞凋亡。
T65684	H-Asp(OcHx)-OH
	H-Asp(OcHx)-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65684，CAS号为 112259-66-2。
T81433	p-NH2-CHX-A"-DTPA
	p-NH2-CHX-A"-DTPA 是双功能螯合剂。

化合物

Cat.No: T22843

Target: Retinoid Receptor

Cat.No: T32107

Synonym: HX 603

Cat.No: T21369

Synonym: Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX

Target: Antibacterial

Cat.No: T70237

Cat.No: T22844

Target: Others

Cat.No: T3647

Synonym: HX 1171,HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone),1-O-hexyl-2,3,5-trimethylhydroquinone

Target: Reactive Oxygen Species

Cat.No: T25510

Synonym: HX 1,HX-1

Cat.No: T80984

Synonym: GEN-1029,HexaBody-DR5/DR5,Hx-DR5-01/05

Isonitrosoacetone

Cat.No: T70236

Cat.No: T75015

Cat.No: T82568

Target: DNA/RNA Synthesis

Cat.No: T32108

Synonym: HXJ-42,HXJ 42

Target: Others

Cat.No: T13613

Target: STING

Biotinyl-Ahx-Amyloid β-Protein (1-42) (ammonium)

Cat.No: T76465

FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578)

Cat.No: T80120

Target: HSV

Cat.No: T41062

FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro

Cat.No: T80127

Target: Integrin

Cat.No: T82569

Cat.No: T74097

DBCO-PEG4-Ahx-DM1

Cat.No: T17793

Target: Others

Boc-Asp(OcHx)-OH

Cat.No: T65558

HXR9 hydrochloride

Cat.No: T76213

Cat.No: T65684

p-NH2-CHX-A"-DTPA

Cat.No: T81433

Cat. No.	Product Name	Target	Signaling Pathways
T29462	5-OH-HxMF
	5-OH-HxMF is an inducer of neurite growth in PC12 cells through the camp / PKA / CREB pathway.

天然产物

Cat.No: T29462

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03345	Sonic Hedgehog Protein, Mouse, Recombinant (His) Hhg1,Hxl3,9530036O11Rik,Dsh,Hx,sonic hedge...	Mouse	HEK293 Cells
	Sonic Hedgehog Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is Q62226.
TMPY-00980	Hemopexin Protein, Human, Recombinant (His) hemopexin,HX	Human	HEK293 Cells
	Hemopexin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.7 kDa and the accession number is P02790.
TMPY-01603	Hemopexin Protein, Mouse, Recombinant (His) hemopexin,Hpxn,hx	Mouse	HEK293 Cells
	Hemopexin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is Q91X72.
TMPK-00778	HPN Protein, Human, Recombinant (His) Hemopexin,Hepsin,HPN,FLJ56652,HPX,HX,TMPRSS1,Hpxn	Human	HEK293 Cells
	HPN Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42 kDa and the accession number is P05981.
TMPK-00724	HPN Protein, Mouse, Recombinant (His) Hemopexin,TMPRSS1,Hpxn,HPX,FLJ56652,Hepsin,HPN,HX	Mouse	HEK293 Cells
	HPN Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.2 kDa and the accession number is O35453-1.
TMPY-04192	HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) Gag-p24	HIV	E. coli
	HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P04591.
TMPH-01993	PDHX Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. PDHX Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 55.5 kDa and the accession number is O00330.
TMPH-00980	DHX33 Protein, Human, Recombinant (His) ATP-dependent RNA helicase DHX33,DEAH box protein 3...	Human	E. coli
	DHX33 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-04150	HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) Gag-Pol	HIV	E. coli
	HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 53.6 kDa and the accession number is P04585.
TMPY-00410	EPHX2 Protein, Human, Recombinant (His) SEH,CEH,epoxide hydrolase 2, cytoplasmic	Human	Baculovirus Insect Cells
	Genetic variation in EPHX2 was significantly associated with risk of incident CHD in Caucasians, implicating EPHX2 as a potential cardiovascular disease-susceptibility gene. Single nucleotide polymorphisms (SNPs) in the human EPHX2 gene had been implicated in susceptibility to cardiovascular disease, including stroke. The human EPHX2 mutations may in part explain the genetic variability in sensitivity to ischemic brain injury and stroke outcome. Epoxide hydrolase is involved in metabolism of vas...
TMPH-00974	DHX9 Protein, Human, Recombinant (His & SUMO) Nuclear DNA helicase II,ATP-dependent RNA helicase A,NDH II,...	Human	E. coli
	DHX9 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00973	DHX36 Protein, Human, Recombinant (His & Myc) DEAH-box protein 36,G4R1,ATP-dependent DNA/RNA helicase D	Human	E. coli
	DHX36 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is Q9H2U1.
TMPH-01298	EPHX1 Protein, Human, Recombinant (His)	Human	E. coli
	Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol.
TMPY-04161	HIV-p66/RT-p66 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) Gag-Pol	HIV	E. coli
	HIV-p66/RT-p66 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 66.7 kDa and the accession number is P04585.
TMPY-00320	APOA1BP Protein, Human, Recombinant (His) YJEFN1,apolipoprotein A-I binding protein,AIBP	Human	HEK293 Cells
	APOA1BP, now renamed NAXE, encodes an epimerase essential in the cellular metabolite repair for NADHX and NADPHX. The enzyme catalyzes the epimerization of NAD(P)HX, thereby avoiding the accumulation of toxic metabolites.Pathogenic biallelic mutations in NAXE in children from four families with (sub-) acute-onset ataxia, cerebellar edema, spinal myelopathy, and skin lesions.

重组蛋白

Sonic Hedgehog Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03345

Species: Mouse

Expression System: HEK293 Cells

Hemopexin Protein, Human, Recombinant (His)

Cat.No: TMPY-00980

Species: Human

Expression System: HEK293 Cells

Hemopexin Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01603

Species: Mouse

Expression System: HEK293 Cells

HPN Protein, Human, Recombinant (His)

Cat.No: TMPK-00778

Species: Human

Expression System: HEK293 Cells

HPN Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00724

Species: Mouse

Expression System: HEK293 Cells

HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His)

Cat.No: TMPY-04192

Species: HIV

Expression System: E. coli

PDHX Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01993

Species: Human

Expression System: E. coli

DHX33 Protein, Human, Recombinant (His)

Cat.No: TMPH-00980

Species: Human

Expression System: E. coli

HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)

Cat.No: TMPY-04150

Species: HIV

Expression System: E. coli

EPHX2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00410

Species: Human

Expression System: Baculovirus Insect Cells

DHX9 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-00974

Species: Human

Expression System: E. coli

DHX36 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00973

Species: Human

Expression System: E. coli

EPHX1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01298

Species: Human

Expression System: E. coli

HIV-p66/RT-p66 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)

Cat.No: TMPY-04161

Species: HIV

Expression System: E. coli

APOA1BP Protein, Human, Recombinant (His)

Cat.No: TMPY-00320

Species: Human

Expression System: HEK293 Cells

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