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Cat. No. | Product Name | Target | Signaling Pathways |
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T76148 |
Glucose oxidase
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Endogenous Metabolite | Metabolism |
Glucose oxidase 是从真菌黑曲霉中提取的酶,是食品工业中一种重要的工业用酶, 广泛用于葡萄酒、啤酒、果汁、奶粉等食品脱氧、面粉改良、防止食品褐变等方面。Glucose oxidase 具有抗氧化和潜在的抗癌活性。 | |||
T6651 |
Safinamide mesylate
PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate,沙芬酰胺甲磺酸盐 |
MAO; Monoamine Oxidase | Metabolism; Neuroscience |
Safinamide mesylate (EMD 1195686 mesylate) 是选择性的、有效的、可逆的单胺氧化酶 B 的抑制剂,对 MAO-A 选择性较低。它能够阻断钠通道和调节谷氨酸释放。它具有神经保护作用,可用于研究帕金森病、缺血脑卒中等疾病。 | |||
T40844 |
2,4-Dimethoxybenzyl alcohol
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2,4-Dimethoxybenzyl alcohol, an aromatic alcohol, is utilized as a substrate by glucose-methanol-choline (GMC) oxidoreductase, which exhibits aryl-alcohol oxidase properties. | |||
T37786 |
1-thio-β-D-Glucose (sodium salt)
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1-thio-β-D-Glucose is an analog of β-D-glucose in which sulfur replaces the hydroxyl group at the one position. The thiol group allows diverse chemical reactions, including click chemistry and polymerization. 1-thio-β-D-Glucose can be labeled with technetium-99m for analytical and diagnostic procedures. It can also be used as a substrate for glucose oxidase, which leads to the production of 1-thio-β-D-gluconic acid. | |||
T73896 |
Glucose-6-phosphate dehydrogenase
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Glucose-6-phosphate dehydrogenase 是戊糖磷酸途径的限速酶。Glucose-6-phosphate dehydrogenase 是抗氧化途径、一氧化氮合酶、NADPH 氧化酶、细胞色素 p450 等系统中 NADPH 的主要来源。Glucose-6-phosphate dehydrogenase 可用于糖尿病、醛固酮诱导的内皮功能障碍和癌症的研究。 | |||
T36418 |
O-Desmethyl-N-deschlorobenzoyl Indomethacin
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O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin .1It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 μM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase.2It has also been used in the synthesis of prostaglandin D2receptor antagonists.3 1.Evans, M.A., Papazafiratou, C., Bhat, R., et al.Indomethacin metabolism ... | |||
T35860 |
AP39
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AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP39 (30-300 nM) dose-dependently increases H2S levels in endothelial cells, predominantly in mitochondrial regions. It stimulates mitochondrial electron transport and improves cellular bioenergetic function at lower concentrations (30-100 nM), while having an i... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN2126 |
Quercetin-3-O-glucose-6''-acetate
6"-O-Acetylisoquercitrin,槲皮素-3-O-葡萄糖苷-6′′-乙酯 |
NADPH-oxidase; ROS; NADPH | Immunology/Inflammation; Metabolism |
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) 是 NADPH 氧化酶的抑制剂。 Quercetin-3-O-glucose-6''-acetate 具有抗氧化活性。 | |||
T19117 |
3-Deoxyglucosone
3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose |
GPX; Glucagon Receptor | GPCR/G Protein; oxidation-reduction |
3-Deoxyglucosone(3-Deoxy-D-glucosone) 是美拉德反应和多元醇反应的中间体途径合成。3-Deoxyglucosone 与蛋白质氨基快速反应形成晚期糖基化末端蛋白 (AGEs)。3-Deoxyglucosone 可使谷胱甘肽过氧化物酶失活,可与低葡萄糖协同作用以增强 GLP-1 分泌,可以作为糖尿病生物学检测的标志物。 | |||
TN6515 |
Selaginellin
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Selaginellin has a neuroprotective effect against L-glutamate-induced neurotoxicity through mechanisms related to anti-oxidation and anti-apoptosis via scavenging reactive oxygen species and up-regulating the expression of klotho gene. Selaginellin shows |