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Search Results for " flufenamic acid-d4 "

3

抑制剂 & 化合物

1

同位素

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Cat. No. Product Name Target Signaling Pathways
T71301 Opaganib HCl

Others Others
ABC294640, also known as Opaganib, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. This may eventually lead to the induction of apoptosis a...
T6750 Opaganib

ABC294640

S1P Receptor GPCR/G Protein
Opaganib (ABC294640) 是选择性和竞争性的鞘氨醇激酶 2 (SK2) 抑制剂,Ki 为 9.8 μM。
T0858 Flufenamic acid

Arlef,Nichisedan,氟灭酸,氟芬那酸,Achless

Potassium Channel; Calcium Channel; Chloride channel; COX; AMPK; Parasite Chromatin/Epigenetic; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
Flufenamic acid (Arlef) 是一种非甾体类抗炎剂,是一种邻氨基苯甲酸衍生物,具有镇痛、抗炎和解热的特性。 它用于肌肉骨骼和关节疾病。

化合物

Opaganib HCl
Cat.No: T71301
Synonym:
Target: Others
Opaganib
Cat.No: T6750
Synonym: ABC294640
Target: S1P Receptor
Flufenamic acid
Cat.No: T0858
Synonym: Arlef,Nichisedan,氟灭酸,氟芬那酸,Achless
Target: Potassium Channel, Calcium Channel, Chloride channel, COX, AMPK, Parasite
Cat. No. Product Name Target Signaling Pathways
T71303 Flufenamic Acid-d4

Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP or A23187 in human polymorphonuclear...

同位素

Flufenamic Acid-d4
Cat.No: T71303
Synonym:
Target:
TargetMol Loading
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