Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3060 |
Fasudil hydrochloride
Fasudil (HA-1077) HCl,盐酸法舒地尔,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877 |
ROCK; Serine/threonin kinase; Calcium Channel; HIV Protease; PKA; PKC; Autophagy | Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors |
Fasudil hydrochloride (HA-1077) 是一种非特异性RhoA/ROCK 抑制剂,也抑制蛋白激酶,对 ROCK1、PKA、PKC 和 MLCK 的 Ki 值分别为 0.33 μM、1.0 μM、9.3 μM 和 55 μM。 | |||
T70108 | Fasudil hydrochloride hydrate | ||
Fasudil hydrochloride hydrate is an HCl salt of Fasudil -- a Rho-kinase (ROCK) inhibitor that has been shown to be effective in hindering the development of mature Cerebral Cavernous Malformation (CCM) lesions as well as reducing portal venous pressure in cirrhotic rats. | |||
T70107 |
Olcorolimus
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Olcorolimus inhibits single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mRNA expression for interleukin (IL)-4 and IL-5 | |||
T64582 | Fasudil hydrochloride semihydrate | ||
Fasudil hydrochloride semihydrate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64582。 |