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Search Results for " dez "

Targets Recommended: Mitophagy p38 MAPK Autophagy

5

抑制剂 & 化合物

3

天然产物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T1764	Adezmapimod PB 203580,4-(4-氟苯基)-2-(4-甲基亚磺酰基苯基)-5-(4-吡啶基)-1H-咪唑,RWJ 64809,SB203580	Mitophagy; p38 MAPK; Autophagy	Autophagy; MAPK
	Adezmapimod (SB 203580) 是一种 p38 MAPK 抑制剂 (IC50=0.3-0.5 μM)，具有选择性和 ATP 竞争性。Adezmapimod 具有自噬和线粒体自噬的激活活性。Adezmapimod 显示出比 PKB、LCK 和 GSK-3β 高 100 倍以上的选择性。
T16718	Radezolid RX-1741,雷得唑来	Antibacterial; Antibiotic	Microbiology/Virology
	Radezolid (RX-1741) 是一种噁唑烷酮类抗生素。它对衣原体，军团菌葡萄球菌，和Linezolid 耐药菌株有活性。
T27157	Dezapelisib INCB-040093,INCB 040093,INCB040093
	Dezapelisib is an orally bioavailable, selective inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinases (PI3K). INCB040093 prevents both the production of the second messenger phosphatidylinositol-3,4,5-trisp
T31406	Dezaguanine Dezaguanina,NSC 261726,CI-908,CI 908
	Dezaguanine is a novel antipurine antimetabolite with significant activity against transplantable rodent solid tumors, particularly breast adenocarcinoma.
T23986	Dezinamide ADD94057,ADD-94057,ADD 94057
	Dezinamide is a potential antiepileptic drug. It shows preliminary evidence of efficacy and safety in an open-label study.

化合物

Cat.No: T1764

Synonym: PB 203580,4-(4-氟苯基)-2-(4-甲基亚磺酰基苯基)-5-(4-吡啶基)-1H-咪唑,RWJ 64809,SB203580

Target: Mitophagy, p38 MAPK, Autophagy

Cat.No: T16718

Synonym: RX-1741,雷得唑来

Target: Antibacterial, Antibiotic

Cat.No: T27157

Synonym: INCB-040093,INCB 040093,INCB040093

Cat.No: T31406

Synonym: Dezaguanina,NSC 261726,CI-908,CI 908

Cat.No: T23986

Synonym: ADD94057,ADD-94057,ADD 94057

Cat. No.	Product Name	Target	Signaling Pathways
TN1731	Hernandezine	TNF; ROS; P-gp; AMPK	Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; PI3K/Akt/mTOR signaling
	Hernandezine 是 AMPK 激动剂的激动剂，也是癌细胞中 ABCB1 介导的 MDR 的特异性逆转剂。
TN6336	Lespedezaflavanone H
	Lespedezaflavanone H 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6336，CAS号为 138822-59-0。
TN6069	Thalidezine
	Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death, it can inhibit the growth of mouse L1210 cells in vitro. Thalidezine possesses antimicrobial activity against Mycobacterium sme

天然产物

Cat.No: TN1731

Target: TNF, ROS, P-gp, AMPK

Lespedezaflavanone H

Cat.No: TN6336

Cat.No: TN6069

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01082	CMKLR1 Protein, Human, Recombinant (His) CMKLR1,G-protein coupled receptor ChemR23,G-protein coupled ...	Human	E. coli
	CMKLR1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.1 kDa and the accession number is Q99788.

重组蛋白

CMKLR1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01082

Species: Human

Expression System: E. coli

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