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Targets Recommended: Histone Demethylase HDAC

8

抑制剂 & 化合物

5

天然产物

8

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T10864 Corin

Histone Demethylase; HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
Corin 是 HDAC1(IC50 = 147 nM) 和 LSD1(Ki = 110 nM) 的不可逆抑制剂。
T34879 Tiliacorine

Tiliacorine is a dibenzodioxin biphenylalkaloid.
T31500 Dinklacorine

Dinklacorine is a biphenyl dibenzodioxin alkaloid.
T2774L Lycorine hydrochloride monohydrate

Lycorine hydrochloride monohydrate is a bioactive chemical.
T124860 Hypecorinine

Hypecorinine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124860。
T35238 Yanangcorinin

Yanangcorinine

Yanangcorinin is a biochemical.
T33030 Lycorine methiodide

Lycorine methiodide is a bioactive chemical.
T125103 Pseudolycorine

Pseudolycorine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125103。

化合物

Corin
Cat.No: T10864
Synonym:
Target: Histone Demethylase, HDAC
Tiliacorine
Cat.No: T34879
Synonym:
Target:
Dinklacorine
Cat.No: T31500
Synonym:
Target:
Lycorine hydrochloride monohydrate
Cat.No: T2774L
Synonym:
Target:
Hypecorinine
Cat.No: T124860
Synonym:
Target:
Yanangcorinin
Cat.No: T35238
Synonym: Yanangcorinine
Target:
Lycorine methiodide
Cat.No: T33030
Synonym:
Target:
Pseudolycorine
Cat.No: T125103
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3324 Lycorine

Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱

Apoptosis; Virus Protease; Antibacterial; AChR; Fatty Acid Synthase Apoptosis; Metabolism; Microbiology/Virology; Neuroscience
Lycorine (Narcissine) 是从金眼科植物科中提取的一种天然生物碱。它是一种具有口服活性的SCAP 抑制剂,Kd 值 15.24 nM。它也是黑色素瘤血管生成抑制剂,有用于前列腺癌和代谢疾病的研究潜力。
T3S1729 Dihydrolycorine

Others Others
Dihydrolycorine 是分离自Lycoris radiate 草药中,是一种真核细胞中蛋白质合成的抑制剂。
T2774 Lycorine hydrochloride

石蒜碱,Licorine hydrochloride,Galanthidine hydrochloride,Narcissine hydrochloride,Lycorine chloride,Amarylline hydrochloride,盐酸石蒜碱

Virus Protease; HCV Protease; Antibacterial; Autophagy Autophagy; Microbiology/Virology; Proteases/Proteasome
Lycorine hydrochloride (Narcissine hydrochloride) 是黑色素瘤血管生成抑制剂,是一种来自石蒜的主要活性成分,抑制 Hey1B 细胞的有丝分裂增殖,IC50值为 1.2 μM,具有抗肿瘤活性。
T82590 Delcorine

Delcorine,一种C19-二萜生物碱,源自Delphinium anthriscifolium var. savatieri草药全草的分离提取。
TN4388 Kielcorin

Antifection Microbiology/Virology
Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolated human neutrophils (IC (50) = 965.21 ± 65.80 uM). trans-Kielcorin has hepatoprotective activity, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes.

天然产物

Lycorine
Cat.No: T3324
Synonym: Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱
Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase
Dihydrolycorine
Cat.No: T3S1729
Synonym:
Target: Others
Lycorine hydrochloride
Cat.No: T2774
Synonym: 石蒜碱,Licorine hydrochloride,Galanthidine hydrochloride,Narcissine hydrochloride,Lycorine chloride,Amarylline hydrochloride,盐酸石蒜碱
Target: Virus Protease, HCV Protease, Antibacterial, Autophagy
Delcorine
Cat.No: T82590
Synonym:
Target:
Kielcorin
Cat.No: TN4388
Synonym:
Target: Antifection
Cat. No. Product Name Species Expression System
TMPH-00986 CORIN Protein, Human, Recombinant (His)

TMPRSS10,Pro-ANP-converting enzyme,Heart-specific serine pro...

Human E. coli
CORIN Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.0 kDa and the accession number is Q9Y5Q5.
TMPY-01608 Decorin Protein, Human, Recombinant (His)

PGS2,PG40,CSCD,decorin,SLRR1B,DSPG2,PGII

Human HEK293 Cells
Decorin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is P07585-1.
TMPH-00264 Decorin Protein, Bovine, Recombinant (His)

Decorin,Bone proteoglycan II,DCN,PG-S2

Bovine E. coli
May affect the rate of fibrils formation. Decorin Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.5 kDa and the accession number is P21793.
TMPH-02337 Hydrophobin-1 Protein, Hypocrea jecorina, Recombinant (His & SUMO)

Hypocrea jecorina E. coli
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures. Hydrophobin-1 Protein, Hypocrea jecorina, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 23.5 kDa and the accession number is P52754.
TMPY-05038 Decorin Protein, Human, Recombinant

PGS2,decorin,PG40,CSCD,PGII,SLRR1B,DSPG2

Human HEK293 Cells
Decorin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38 kDa and the accession number is P07585-1.
TMPJ-00924 Decorin Protein, Mouse, Recombinant (His)

PG40,Bone proteoglycan II,Decorin,Dcn,PG-S2

Mouse HEK293 Cells
Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a guardian from the matrix. Mature human Decorin contains 12 tandem LRR and shares 80% and 78% aa sequence identity with mouse and rat Decorin, respectively. Decorin embraces numerous functions including: regulation of collagen fibrillogenesis, hepatic carcinogenesis, fetal membrane a...
TMPY-00774 Decorin Protein, Human, Recombinant (hFc)

PGII,CSCD,DSPG2,PGS2,PG40,decorin,SLRR1B

Human HEK293 Cells
Decorin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63. kDa and the accession number is P07585-1.
TMPH-02338 HFBII Protein, Hypocrea jecorina, Recombinant (B2M & His & JD)

Hypocrea jecorina E. coli
Responsible for spore hydrophobicity and protection. HFBII Protein, Hypocrea jecorina, Recombinant (B2M & His & JD) is expressed in E. coli expression system with N-10xHis-B2M-JD tag. The predicted molecular weight is 12.7 kDa and the accession number is P79073.

重组蛋白

CORIN Protein, Human, Recombinant (His)
Cat.No: TMPH-00986
Species: Human
Expression System: E. coli
Decorin Protein, Human, Recombinant (His)
Cat.No: TMPY-01608
Species: Human
Expression System: HEK293 Cells
Decorin Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00264
Species: Bovine
Expression System: E. coli
Hydrophobin-1 Protein, Hypocrea jecorina, Recombinant (His & SUMO)
Cat.No: TMPH-02337
Species: Hypocrea jecorina
Expression System: E. coli
Decorin Protein, Human, Recombinant
Cat.No: TMPY-05038
Species: Human
Expression System: HEK293 Cells
Decorin Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00924
Species: Mouse
Expression System: HEK293 Cells
Decorin Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00774
Species: Human
Expression System: HEK293 Cells
HFBII Protein, Hypocrea jecorina, Recombinant (B2M & His & JD)
Cat.No: TMPH-02338
Species: Hypocrea jecorina
Expression System: E. coli
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