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Search Results for " cn2 "

7

抑制剂 & 化合物

20

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T82700	Cn2 toxin β-Mammal toxin Cn2
	Cn2 toxin为一β类毒素，具有与电压门控钠通道（Nav）的电压感应域结合的能力。
T11373	GCN2-IN-1 A-92	Others	Others
	GCN2-IN-1 (A-92) 是一种有效的一般性调控阻遏蛋白激酶 2 抑制剂，可作为化疗药物用于癌症治疗的研究。
T11374	GCN2-IN-6	Others; PERK	Apoptosis; Others
	GCN2-IN-6 经酶法和细胞分析证实，是一种口服有效GCN2抑制剂，IC50分别为1.8 nM 和9.3 nM。GCN2-IN-6 还是 eIF2α 激酶PERK 抑制剂，在酶法测定和细胞测定中的IC50分别为 0.26 nM 和 230 nM。
T7494	TCN238 TCN 238	GluR	Neuroscience
	TCN238 是一种可口服的代谢型谷氨酸受体 4 正变构调节剂，EC50值为 1 μM。
T11375	GCN2iB	Others; Autophagy	Autophagy; Others
	GCN2iB 是一种 ATP 竞争性的一般控制非抑制性 2 抑制剂，IC50 为 2.4 nM。
T69829	GCN2iB acetate
	GCN2iB is a GCN2 inhibitor. GCN2iB may be useful for the treatment of cancer. The inhibition of GCN2 sensitizes cancer cells with low basal-level expression of asparagine synthetase (ASNS) to the antileukemic agent L-asparaginase (ASNase) in vitro and in vivo.
T63699	GCN2-IN-7
	GCN2-IN-7 是选择性的、口服具有活力的 general control nonderepressible 2(GCN2) 抑制剂，其 IC50 值为 5 nM，在体内表现出抗肿瘤效果。

化合物

Cat.No: T82700

Synonym: β-Mammal toxin Cn2

Cat.No: T11373

Synonym: A-92

Target: Others

Cat.No: T11374

Target: Others, PERK

Cat.No: T7494

Synonym: TCN 238

Target: GluR

Cat.No: T11375

Target: Others, Autophagy

Cat.No: T69829

Cat.No: T63699

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00361	Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His) Toxin 2,Beta-mammal toxin Cn2,Tox...	Centruroides noxius	P. pastoris (Yeast)
	Mammal beta-toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the activation voltage to more negative potentials. This toxin is active against mammals. Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 9.6 kDa and the accession number is P01495.
TMPY-01773	CNDP2 Protein, Human, Recombinant (His) CNDP dipeptidase 2 (metallopeptidase M...	Human	Baculovirus Insect Cells
	CNDP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.2 kDa and the accession number is CAC69883.1.
TMPH-01199	CNDP2 Protein, Human, Recombinant (E. coli, His) HEL-S-13,CPGL,Threonyl dipeptidase,PEPA,CNDP dipept...	Human	E. coli
	CNDP2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPY-01739	CNDP2 Protein, Mouse, Recombinant (His) C76600,Dip-2,Pep-1,Cn2,0610010E05...	Mouse	Baculovirus Insect Cells
	CNDP2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.22 kDa and the accession number is Q9D1A2.
TMPY-01003	TCN2 Protein, Human, Recombinant (His) II,TC-2,D22S750,TC,TCII,TC2	Human	HEK293 Cells
	TCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P20062-1.
TMPY-00873	Lipocalin-2/LCN2 Protein, Human, Recombinant (His) MSFI,24p3,lipocalin 2,NGAL,Lipocalin-2...	Human	HEK293 Cells
	Lipocalin-2/LCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P80188-1.
TMPY-00988	Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) 24p3,lipocalin 2,AW212	Mouse	HEK293 Cells
	Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.3 kDa and the accession number is P11672.
TMPY-02316	Lipocalin-2/LCN2 Protein, Rat, Recombinant (His) lipocalin 2	Rat	Baculovirus Insect Cells
	Lipocalin-2/LCN2 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 21.9 kDa and the accession number is P30152.
TMPJ-01163	CTGF/CCN2 Protein, Human, Recombinant (HEK293, His) CTGF,Connective tissue growth factor	Human	HEK293 Cells
	Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physio...
TMPY-05203	Lipocalin-2/LCN2 Protein, Mouse, Recombinant lipocalin 2,AW21222<...	Mouse	HEK293 Cells
	Lipocalin-2/LCN2 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.9 kDa and the accession number is P11672.
TMPJ-01113	RCN2 Protein, Human, Recombinant (His) Reticulocalbin-2,ERC55,RCN2,E6BP	Human	HEK293 Cells
	Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 cou...
TMPK-01000	CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated CTGF,CCN2,IBP-8,IGFBP8,Fisp12,CTG...	Human	HEK293 Cells
	Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells. CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells wi...
TMPJ-01162	CTGF/CCN2 Protein, Human, Recombinant (hFc) IGFBP8,Connective tissue growth factor,Hypertrophic chondroc...	Human	HEK293 Cells
	CTGF/CCN2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 67-81 KDa and the accession number is Q5M8T4.
TMPK-00672	CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His) CTGRP,CTGF,IBP-8,CCN2,NOV2,HCS	Rhesus	HEK293 Cells
	Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells. CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His ta...
TMPH-01069	CTGF/CCN2 Protein, Human, Recombinant (His) Hypertrophic chondrocyte-specific protein 24,CC...	Human	E. coli
	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. CTGF/CCN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.1 kDa and...
TMPJ-01161	CTGF/CCN2 Protein, Human, Recombinant IGFBP-8,CCN family member 2,IBP-8,Connecti...	Human	HEK293 Cells
	CTGF/CCN2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-25 KDa and the accession number is Q5M8T4.
TMPY-03697	SCN2B Protein, Human, Recombinant (His) ATFB14,sodium channel, voltage gated, type II beta subunit,s...	Human	HEK293 Cells
	SCN2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.7 kDa and the accession number is O60939.
TMPH-02568	CTGF/CCN2 Protein, Mouse, Recombinant (GST) betaIG-M2,Connective tissue growth factor,Protein F...	Mouse	E. coli
	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
TMPY-02192	TCN2 Protein, Mouse, Recombinant (His) Tcn-2,transcobalamin II,AW208754	Mouse	HEK293 Cells
	TCN2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is O88968.
TMPY-03183	SCN2B Protein, Human, Recombinant (hFc) sodium channel, voltage gated, type II beta subunit,sodium c...	Human	HEK293 Cells
	SCN2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is O60939.

重组蛋白

Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His)

Cat.No: TMPH-00361

Species: Centruroides noxius

Expression System: P. pastoris (Yeast)

CNDP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01773

Species: Human

Expression System: Baculovirus Insect Cells

CNDP2 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01199

Species: Human

Expression System: E. coli

CNDP2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01739

Species: Mouse

Expression System: Baculovirus Insect Cells

TCN2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01003

Species: Human

Expression System: HEK293 Cells

Lipocalin-2/LCN2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00873

Species: Human

Expression System: HEK293 Cells

Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00988

Species: Mouse

Expression System: HEK293 Cells

Lipocalin-2/LCN2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-02316

Species: Rat

Expression System: Baculovirus Insect Cells

CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)

Cat.No: TMPJ-01163

Species: Human

Expression System: HEK293 Cells

Lipocalin-2/LCN2 Protein, Mouse, Recombinant

Cat.No: TMPY-05203

Species: Mouse

Expression System: HEK293 Cells

RCN2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01113

Species: Human

Expression System: HEK293 Cells

CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01000

Species: Human

Expression System: HEK293 Cells

CTGF/CCN2 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01162

Species: Human

Expression System: HEK293 Cells

CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00672

Species: Rhesus

Expression System: HEK293 Cells

CTGF/CCN2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01069

Species: Human

Expression System: E. coli

CTGF/CCN2 Protein, Human, Recombinant

Cat.No: TMPJ-01161

Species: Human

Expression System: HEK293 Cells

SCN2B Protein, Human, Recombinant (His)

Cat.No: TMPY-03697

Species: Human

Expression System: HEK293 Cells

CTGF/CCN2 Protein, Mouse, Recombinant (GST)

Cat.No: TMPH-02568

Species: Mouse

Expression System: E. coli

TCN2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02192

Species: Mouse

Expression System: HEK293 Cells

SCN2B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03183

Species: Human

Expression System: HEK293 Cells

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