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Search Results for " ciprofloxacin "

20

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1640	Ciprofloxacin Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ciprofloxacin (Bay-09867) 是一种有高抗菌活性的氟喹诺酮类抗生素。
T0250	Ciprofloxacin monohydrochloride Bay-09867 (hydrochloride),Ciprofloxacin HCl,盐酸环丙沙星,环丙沙星盐酸盐,Ciprofloxacin hydrochloride	DNA gyrase; Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) 是一种高抗菌活性的氟喹诺酮类抗生素。
T1733	Ciprofloxacin EP IMpurity A Q-Acid,Fluoroquinolonic Acid,环丙羧酸,Ciprofloxacin Impurity A	Antibiotic	Microbiology/Virology
	Ciprofloxacin EP IMpurity A (Fluoroquinolonic Acid) 是一种抗生素和抗菌剂。
T36030	Desethylene Ciprofloxacin (hydrochloride)
	Desethylene ciprofloxacin is a major metabolite of ciprofloxacin . It is also a degradation product of ciprofloxacin that can be created through advanced oxygenation processes as a potential way to remove ciprofloxacin from wastewater. It is also created during degradation of ciprofloxacin by chlorination.
T66299	Ciprofloxacin lactate
	Ciprofloxacin lactate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66299，CAS号为 97867-33-9。
T8606	n-acetylciprofloxacin N-乙酰基环丙沙星,3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1	Others	Others
	n-acetylciprofloxacin (3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1) 是 H37Rv 的抑制剂。
T29531	ABT-719 HCl A-816719.1,A 816719.1,ABT-719,ABT719,ABT 719,ABT-719 hydrochloride
	ABT-719 is a 2-pyridinone antimicrobial agent that is more effective against Enterococcus faecalis strains than ciprofloxacin and vancomycin, which showed resistance to ciprofloxacin and vancomycin covering a range of MIC.
T26928	BV600022 BV-600022,BV 600022
	BV600022 is an osteoadsorptive bisphosphonate-ciprofloxacin conjugate with antibacterial activity.
T75001	Antibacterial agent 128
	Antibacterial agent 128 是一种带有可裂解接头的铁载体类似物-环丙沙星 (Ciprofloxacin (Ciprofloxacin )) 偶联物。Antibacterial agent 128 显示出针对铜绿假单胞菌 (MIC 值为 0.25-64 μg/mL) 和类鼻疽伯克氏菌 (MIC 值为 1-32 μg/mL) 的抗生素活性。
T37729	IMP-1700
	IMP-1700 is an inhibitor of bacterial DNA repair.1It potentiates the activity of the quinolone antibiotic ciprofloxacin against methicillin-resistantS. aureus(MRSA) with a combination index value of 0.7. IMP-1700 inhibits the ciprofloxacin-induced bacterial SOS response, a process that repairs DNA damage, in a reporter assay in a concentration-dependent manner. It is also active againstE. coli, as well as methicillin-resistant and -sensitive S. aureus, when used alone (EC50s = 0.5, 0.21, and 3.8...
T28576	Ro 24-6392 Ro 246392,Ro-24-6392
	Ro 24-6392 is an ester-linked co-drug combining ciprofloxacin and desacetylcefotaxime. Ro 24-6392 demonstrats activity against a wide spectrum of aerobic bacteria.
T63157	Antifungal agent 16
	Antifungal agent 16 的抗菌活性与环丙沙星相当，且抗真菌活性高于氟康唑。
T72479	Anticancer agent 66
	Anticancer agent 66 是一种抗癌剂。Anticancer agent 66 在 MCF-7 细胞中诱导细胞凋亡 (apoptosis) 并增加亚 G1 细胞群。Anticancer agent 66 是一种环丙沙星类似物。
T63917	Anticancer agent 67
	Anticancer agent 67 是环丙沙星类似物，是一种抗癌剂，在 MCF-7 细胞中能够诱导细胞凋亡 (apoptosis) 并增加亚 G1 细胞群。
T79202	Anticancer agent 118
	Anticanceragent 118是一种N-酰化环丙沙星衍生物，展现了针对革兰氏阳性(bacterial)菌株的高度活性，以及对前列腺癌PC3细胞的抗增殖能力，适用于抗肿瘤研究。
T78935	Quorum Sensing-IN-2
	Quorum Sensing-IN-2（compound 23e）是一款不影响细菌生长的群体感应抑制剂，具有减少细菌致病性的功能。该化合物在抑制细菌感染方面表现出效力，同时具有极低的溶血活性。在铜绿假单胞菌PAO1引起的菌血症模型中，Quorum Sensing-IN-2与环丙沙星共同作用，显示了协同效应。
T65396	Piperazine 2HCl
	Piperazine (2HCl) is gamma-aminobutyric acid (GABA) agonists and its major effects appear to be on the central nervous system. Piperazine was the anthelmintic with the greatest number of reports of toxicoses and suspected toxicoses in cats. Piperazine neurotoxicity in cats and dogs usually was manifested by muscle tremors, ataxia, and/or behavioral disturbances within 24 hours after estimated daily dose(s) between 20 and 110 mg/kg[1]. For di-substituted derivatives, ciprofloxacin was selected an...
T28314	PD 117588 PD117588,PD-117588
	PD 117588 is a quinolone against bacterial isolates from cancer patients. PD 117558 has a broad antimicrobial spectrum with excellent activity against all Gram-positive isolates (including methicillin-resistant Staphylococcus aureus, coagulase-negative st
T78732	BO-1
	BO-1是一种苯甲酸酯类抗菌活性化合物。它能够抑制多重耐药金黄色葡萄球菌，同时与环丙沙星等抗生素显示协同效应。此外，BO-1可逆转该菌株的耐药性，并在小鼠体内降低IL-6及C反应蛋白的水平。
T75296	Pazufloxacin
	Pazufloxacin (T-3761)是氟喹诺酮类广谱抗生素。

化合物

Ciprofloxacin

Cat.No: T1640

Synonym: Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867

Target: Topoisomerase, Antibacterial, Antibiotic

Ciprofloxacin monohydrochloride

Cat.No: T0250

Synonym: Bay-09867 (hydrochloride),Ciprofloxacin HCl,盐酸环丙沙星,环丙沙星盐酸盐,Ciprofloxacin hydrochloride

Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic

Ciprofloxacin EP IMpurity A

Cat.No: T1733

Synonym: Q-Acid,Fluoroquinolonic Acid,环丙羧酸,Ciprofloxacin Impurity A

Target: Antibiotic

Desethylene Ciprofloxacin (hydrochloride)

Cat.No: T36030

Ciprofloxacin lactate

Cat.No: T66299

n-acetylciprofloxacin

Cat.No: T8606

Synonym: N-乙酰基环丙沙星,3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1

Target: Others

Cat.No: T29531

Synonym: A-816719.1,A 816719.1,ABT-719,ABT719,ABT 719,ABT-719 hydrochloride

Cat.No: T26928

Synonym: BV-600022,BV 600022

Antibacterial agent 128

Cat.No: T75001

Cat.No: T37729

Cat.No: T28576

Synonym: Ro 246392,Ro-24-6392

Antifungal agent 16

Cat.No: T63157

Anticancer agent 66

Cat.No: T72479

Anticancer agent 67

Cat.No: T63917

Anticancer agent 118

Cat.No: T79202

Quorum Sensing-IN-2

Cat.No: T78935

Piperazine 2HCl

Cat.No: T65396

Cat.No: T28314

Synonym: PD117588,PD-117588

Cat.No: T78732

Cat.No: T75296

Cat. No.	Product Name	Target	Signaling Pathways
T8130	Ciprofloxacin hydrochloride monohydrate Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,环丙沙星盐酸盐一水合物,Ceprimax,盐酸环丙沙星(一水物),Ciloxan	Antibacterial; Antibiotic	Microbiology/Virology
	Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) 是一种具有高效抗菌活性的氟喹诺酮类抗生素。
TN3404	Altholactone	BCL; p38 MAPK; ROS; Akt; Caspase; Antifection; p53	Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of various types of cancer cells through inducing apoptosis via oxidative stress, including bladd

天然产物

Ciprofloxacin hydrochloride monohydrate

Cat.No: T8130

Synonym: Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,环丙沙星盐酸盐一水合物,Ceprimax,盐酸环丙沙星(一水物),Ciloxan

Target: Antibacterial, Antibiotic

Cat.No: TN3404

Target: BCL, p38 MAPK, ROS, Akt, Caspase, Antifection, p53

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